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Article ; Online: Data Quality in Healthcare for the Purpose of Artificial Intelligence: A Case Study on ECG Digitalization.

Ranjbar, Arian / Ravn, Jesper

Studies in health technology and informatics

2023 Volume 305, Page(s) 471–474

Abstract: The quantity of data generated within healthcare is increasing exponentially. Following this development, the interest of using data driven methodologies such as machine learning is on a steady rise. However, the quality of the data also needs to be ... ...

Abstract	The quantity of data generated within healthcare is increasing exponentially. Following this development, the interest of using data driven methodologies such as machine learning is on a steady rise. However, the quality of the data also needs to be considered, since information generated for human interpretation may not be optimal for quantitative computer-based analysis. This work investigates dimensions of data quality for the purpose of artificial intelligence applications in healthcare. Particularly, ECG is studied which traditionally rely on analog prints for initial examination. A digitalization process for ECG is implemented, together with a machine learning model for heart failure prediction, to quantitatively compare results based on data quality. The digital time series data provide a significant accuracy increase, compared to scans of analog plots.
MeSH term(s)	Humans ; Artificial Intelligence ; Data Accuracy ; Machine Learning ; Delivery of Health Care ; Electrocardiography
Language	English
Publishing date	2023-06-19
Publishing country	Netherlands
Document type	Journal Article
ISSN	1879-8365
ISSN (online)	1879-8365
DOI	10.3233/SHTI230534
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Article: Mortality patterns in patients with Staphylococcus aureus bacteremia during the COVID-19 pandemic: Predictors and insights.

Abdollahi, Arash / Nojomi, Marzieh / Karimi, Yeganeh / Ranjbar, Mitra

Heliyon

2024 Volume 10, Issue 2, Page(s) e24511

Abstract: Objectives: This paper aims to determine the : Methods: A total of 167 SAB samples were collected between March 2020 and March 2022 at a teaching hospital in Tehran, Iran. The patient's baseline data and antibiograms were collected. The outcome of ... ...

Abstract	Objectives: This paper aims to determine the Methods: A total of 167 SAB samples were collected between March 2020 and March 2022 at a teaching hospital in Tehran, Iran. The patient's baseline data and antibiograms were collected. The outcome of the study was in-hospital mortality. Results: The overall in-hospital mortality rate was 41.9 %, with higher mortality observed in patients over 60 years old (P = 0.032), those with community-acquired Conclusion: SAB remains a challenging infection that is amplified by the pandemic. Older age and ICU admission are significant mortality predictors. In settings with a high prevalence of MRSA, factors like age, sex, and quality of care outweigh pathogen-related factors such as antibiotic resistance.
Language	English
Publishing date	2024-01-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e24511
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Article ; Online: Motivating and inhibiting factors influencing the application of mhealth technology in post-abortion care: a review study.

Zolfaqari, Zahra / Ayatollahi, Haleh / Ranjbar, Fahimeh / Abasi, Arezoo

BMC pregnancy and childbirth

2024 Volume 24, Issue 1, Page(s) 73

Abstract: Background: Abortion and its complications are challenges that endanger women's health, especially in developing countries. It seems that the application of mhealth technology can be useful as a safe and affordable strategy in post-abortion care. The ... ...

Abstract	Background: Abortion and its complications are challenges that endanger women's health, especially in developing countries. It seems that the application of mhealth technology can be useful as a safe and affordable strategy in post-abortion care. The purpose of this study was to identify factors influencing the use of mhealth technology in post-abortion care. Methods: This was a review study conducted in 2023 and articles published in English between 2010 and 1st November 2023 were searched in PubMed, Scopus, ProQuest, Web of Science, and Embase databases as well as Google Scholar. Data were collected using a data extraction form and were analyzed narratively. Results: The influencing factors could be divided into the motivating and inhibiting factors. The motivating factors included the subgroups of the individual factors (e.g., saving time), technical factors (e.g., usability), economic factors (e.g., saving costs), and ethico-legal factors (e.g., improving security and confidentiality of the information). Similarly, the inhibiting factors consisted of individual factors (e.g., fear of expressing abortion), technical factors (e.g., a lack of access to the network and the Internet), economic factors (e.g., inappropriate patient financial status), and ethico-legal (e.g., concerns over the security and confidentiality of information). Conclusion: This study underscores the importance of considering various technical and non-technical factors influencing the design and implementation of mHealth technology in post-abortion care. Developers need to address these factors to ensure successful technology adoption and mitigate risks. The findings contribute to the enhancement of women's health and offer insights for future technology acceptance models in the mHealth field.
MeSH term(s)	Pregnancy ; Humans ; Female ; Abortion, Induced ; Databases, Factual ; Fear ; Internet
Language	English
Publishing date	2024-01-22
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	2059869-5
ISSN	1471-2393 ; 1471-2393
ISSN (online)	1471-2393
ISSN	1471-2393
DOI	10.1186/s12884-024-06253-0
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Article ; Online: Comparing the performance of machine learning methods in estimating the shear wave transit time in one of the reservoirs in southwest of Iran.

Dehghani, MohammadRasool / Jahani, Shahryar / Ranjbar, Ali

Scientific reports

2024 Volume 14, Issue 1, Page(s) 4744

Abstract: Shear wave transit time is a crucial parameter in petroleum engineering and geomechanical modeling with significant implications for reservoir performance and rock behavior prediction. Without accurate shear wave velocity information, geomechanical ... ...

Abstract	Shear wave transit time is a crucial parameter in petroleum engineering and geomechanical modeling with significant implications for reservoir performance and rock behavior prediction. Without accurate shear wave velocity information, geomechanical models are unable to fully characterize reservoir rock behavior, impacting operations such as hydraulic fracturing, production planning, and well stimulation. While traditional direct measurement methods are accurate but resource-intensive, indirect methods utilizing seismic and petrophysical data, as well as artificial intelligence algorithms, offer viable alternatives for shear wave velocity estimation. Machine learning algorithms have been proposed to predict shear wave velocity. However, until now, a comprehensive comparison has not been made on the common methods of machine learning that had an acceptable performance in previous researches. This research focuses on the prediction of shear wave transit time using prevalent machine learning techniques, along with a comparative analysis of these methods. To predict this parameter, various input features have been employed: compressional wave transit time, density, porosity, depth, Caliper log, and Gamma-ray log. Among the employed methods, the random forest approach demonstrated the most favorable performance, yielding R-squared and RMSE values of 0.9495 and 9.4567, respectively. Furthermore, the artificial neural network, LSBoost, Bayesian, multivariate regression, and support vector machine techniques achieved R-squared values of 0.878, 0.8583, 0.8471, 0.847 and 0.7975, RMSE values of 22.4068, 27.8158, 28.0138, 28.0240 and 37.5822, respectively. Estimation analysis confirmed the statistical reliability of the Random Forest model. The formulated strategies offer a promising framework applicable to shear wave velocity estimation in carbonate reservoirs.
Language	English
Publishing date	2024-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-55535-2
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Article ; Online: Margin status impact on recurrence of phyllodes tumors in high-risk groups: a retrospective observational study.

Ranjbar, Aliyeh / Zangouri, Vahid / Shokripour, Mansoureh

BMC cancer

2024 Volume 24, Issue 1, Page(s) 48

Abstract: Background: Phyllodes tumor (PT) is an fibroepithelial tumor with potential for local recurrence. The optimal margin for surgical resection of PT is still debated, particularly in cases of positive margins. This study aimed to identify the risk factors ... ...

Abstract	Background: Phyllodes tumor (PT) is an fibroepithelial tumor with potential for local recurrence. The optimal margin for surgical resection of PT is still debated, particularly in cases of positive margins. This study aimed to identify the risk factors for phyllodes tumor recurrence and the effect of a free margin on tumor recurrence by considering these risk factors. Materials and methods: This is a retrospective observational study of patients diagnosed with PT who had undergone surgical management. The data were collected from medical records from 2001 to 2020 in the breast clinic of Shahid Motahhari Clinic of Shiraz. Patients were followed up for at least 3 years after the operation to be checked for local recurrence or distant metastasis at regular intervals. Results: This retrospective study included 319 patients with PT who underwent surgical management. Of these patients, 83.9% (n = 267), 7.6% (n = 24), and 8.5% (n = 27) were classified as benign, borderline, and malignant, respectively. 8.8% of all patients and 7.6% of non-malignant cases experienced local recurrence, and risk factors for recurrence included oral contraceptive use, smoking, size > 4 cm, stromal overgrowth, and stromal cell atypia. A negative surgical margin decreased the prevalence of recurrence in tumors > 4 cm and with stromal overgrowth significantly. Conclusion: The study found that a negative margin in all patients did not reduce the recurrence rate in benign and borderline phyllodes tumors, suggesting close follow up as a reasonable alternative. However, a negative margin may be effective in reducing recurrence in certain high-risk groups.
MeSH term(s)	Humans ; Female ; Phyllodes Tumor/epidemiology ; Phyllodes Tumor/surgery ; Retrospective Studies ; Neoplasm Recurrence, Local/epidemiology ; Stromal Cells ; Breast Neoplasms/epidemiology ; Breast Neoplasms/surgery
Language	English
Publishing date	2024-01-09
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-023-11805-2
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Article ; Online: Coenzyme Q10 and exercise training reinstate middle cerebral artery occlusion-induced behavioral deficits and hippocampal long-term potentiation suppression in aging rats.

Ranjbar, Kamal / Komaki, Alireza / Fayazi, Bayan / Zarrinkalam, Ebrahim

Psychopharmacology

2024

Abstract: Rational: Patients experience post-stroke cognitive impairment during aging. To date, no specific treatment solution has been reported for this disorder.: Objective: The purpose of this study was to evaluate the effects of exercise training and ... ...

Abstract	Rational: Patients experience post-stroke cognitive impairment during aging. To date, no specific treatment solution has been reported for this disorder. Objective: The purpose of this study was to evaluate the effects of exercise training and coenzyme Q10 supplementation on middle cerebral artery occlusion (MCAO) induced behavioral impairment, long-term potentiation inhibition and cerebral infarction size in aging rats. Methods: Fifty aging male rats underwent MCAO surgery and were randomly distributed in to the following groups: 1-Sham, 2- control, 3- Coenzyme Q10, 4- Exercise training and 5- Exercise training with Q10 supplementation (Ex + Q10). Aerobic training groups were allowed to run on a treadmill for 12 weeks. Q10 (50 mg/kg) was administered intragastrically by gavage. Morris water maze, shuttle box and elevated plus maze tests were used to evaluate cognitive function. The population spike (PS) amplitude and slope of excitatory postsynaptic potentials (EPSP) in the dentate gyrus area were recorded as a result of perforant pathway electrical stimulation. Results: Our study showed that Q10 and aerobic training alone ameliorate spatial memory in the acquisition phase, but have no effect on spatial memory in the retention phase. Q10 and exercise training synergistically promoted spatial memory in the retention phase. Q10 and exercise training separately and simultaneously mitigated cerebral ischemia-induced passive avoidance memory impairment in acquisition and retention phases. The EPSP did not differ between the groups, but exercise training and Q10 ameliorate the PS amplitude in hippocampal responses to perforant path stimulation. Exercising and Q10 simultaneously reduced the cerebral infarction volume. Conclusion: Collectively, the findings of the present study imply that 12 weeks of aerobic training and Q10 supplementation alone can simultaneously reverse cerebral ischemia induced neurobehavioral deficits via amelioration of synaptic plasticity and a reduction in cerebral infarction volume in senescent rats.
Language	English
Publishing date	2024-04-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	130601-7
ISSN	1432-2072 ; 0033-3158
ISSN (online)	1432-2072
ISSN	0033-3158
DOI	10.1007/s00213-024-06583-z
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Article ; Online: Validation of Free Formaldehyde Determination Method in DT Vaccine and Tetanus Toxoid Antigen.

Zali, S / Es-Haghi, A / Ranjbar Rafie, H

Archives of Razi Institute

2023 Volume 78, Issue 3, Page(s) 881–888

Abstract: Validation is a Good Manufacturing Practice principle that proves any procedure, process, method, equipment, material, activity, or system actually leads to the expected results. This study validates the method for the determination of free formaldehyde ... ...

Abstract	Validation is a Good Manufacturing Practice principle that proves any procedure, process, method, equipment, material, activity, or system actually leads to the expected results. This study validates the method for the determination of free formaldehyde in biological products (including the diphtheria-tetanus vaccine and tetanus toxoid antigen). The operating procedure of this method is based on pharmacopoeial monographs. It also does not require full validation, although its suitability under the actual condition of use should be verified. Performance characterizations, such as accuracy, intra-precision (repeatability), intermediate precision (inter-precision), linearity, range, and the limit of quantitation, were investigated and calculated. Accuracy and precision were studied at different concentration levels by spiking known amounts of formaldehyde in real samples. The accuracy and precision results were expressed as the recovery and the relative standard deviation (RSD), respectively. Precision was expressed as intra-precision (repeatability) and inter-precision. Intra-precision or repeatability was performed by one operator in one day by adding three levels of concentration to the products. The inter-precision was conducted by one operator in three individual days within the same laboratory at three concentration levels. Range and linearity were assessed by investigating the correlation coefficient of the regression line between different concentrations of formaldehyde and their response. The acceptance criteria and limits were defined for these validation parameters in these biological products. The RSD for intra-day and inter-day precision studies was less than 5% in a medium concentration of linear range. At this concentration level, accuracy was 90%-110%. The method's linearity ranged between 0.0000039%-0.01% w/v of formaldehyde with a correlation coefﬁcient of 0.9999. The results exhibited sufficient linearity, accuracy, precision, and range. Therefore, this method can be used successfully to determine free formaldehyde for biological products.
MeSH term(s)	Animals ; Diphtheria-Tetanus Vaccine ; Tetanus Toxoid ; Formaldehyde
Chemical Substances	Diphtheria-Tetanus Vaccine ; Tetanus Toxoid ; Formaldehyde (1HG84L3525)
Language	English
Publishing date	2023-06-30
Publishing country	Iran
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2555498-0
ISSN	2008-9872 ; 0365-3439
ISSN (online)	2008-9872
ISSN	0365-3439
DOI	10.22092/ARI.2023.358602.2484
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Article: Synergistic effects of modified atmosphere packaging and cinnamaldehyde on bioactive compounds, aerobic mesophilic and psychrophilic bacteria of pomegranate arils during cold storage

Ranjbar, Azam / Ramezanian, Asghar

Chemical and biological technologies in agriculture. 2022 Dec., v. 9, no. 1

2022

Abstract: BACKGROUND: Ready-to-eat pomegranate arils are very perishable. In this research, the effect of packaging with two kinds of films fumigated with cinnamaldehyde (0, 100, 150, and 200 μL L⁻¹), evaluated on bioactive compounds and microbial contamination of ...

Abstract	BACKGROUND: Ready-to-eat pomegranate arils are very perishable. In this research, the effect of packaging with two kinds of films fumigated with cinnamaldehyde (0, 100, 150, and 200 μL L⁻¹), evaluated on bioactive compounds and microbial contamination of pomegranate arils during cold storage. RESULTS: Polyethylene + polyester (PE + PES) film containing cinnamaldehyde, preserved lightness (L), and chroma index (C) as compared with biaxial-oriented polypropylene (BOPP) film containing cinnamaldehyde. Anthocyanin content and phenolic compounds decreased during storage. PE + PES film containing cinnamaldehyde caused a significant delay in decreasing the trend of total antioxidant activity (TAA) during storage. The lowest number of aerobic mesophilic bacteria and psychrophilic bacteria were related to PE + PES film containing cinnamaldehyde. CONCLUSIONS: Packaging with PE + PES film containing 200 μL L⁻¹ cinnamaldehyde was the best treatment for preservation of bioactive compounds and extending the shelf life of pomegranate arils up to 25 days. This new packaging technique is promising for the preservation of pomegranate ready-to-use arils.
Keywords	agriculture ; anthocyanins ; antioxidant activity ; aril ; cold storage ; microbial contamination ; polyesters ; polyethylene ; polypropylenes ; pomegranates ; ready-to-eat foods ; shelf life
Language	English
Dates of publication	2022-12
Size	p. 24.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	2762782-2
ISSN	2196-5641
ISSN	2196-5641
DOI	10.1186/s40538-022-00290-7
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Article ; Online: Palladium-Catalyzed Oxidative Annulation Leading to Substituted Pyrrolo[3,2,1-

Azizzade, Meysam / Rashidi Ranjbar, Parviz / Sajadi, Akram

Organic letters

2023 Volume 25, Issue 11, Page(s) 1823–1828

Abstract: A novel regioselective annulation of propargylic alcohols with simple carbazoles for the construction of [3,2,1- ...

Abstract	A novel regioselective annulation of propargylic alcohols with simple carbazoles for the construction of [3,2,1-
Language	English
Publishing date	2023-03-16
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.3c00244
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Article ; Online: CRISPR Typing of Clinical Strains of

Karimi, Zahra / Ranjbar, Reza / Najafi, Ali

Iranian journal of public health

2023 Volume 52, Issue 8, Page(s) 1758–1763

Abstract: Background: Salmonella: Methods: Salmonella: Results: Overall, 119 strains of various : Conclusion: CRISPR genotyping could provide serotype/spacers dictionary and it is performed at low cost and high speed in comparison to the other typing ... ...

Abstract	Background: Salmonella Methods: Salmonella Results: Overall, 119 strains of various Conclusion: CRISPR genotyping could provide serotype/spacers dictionary and it is performed at low cost and high speed in comparison to the other typing methods. Therefore, the assessment of CRISPR and spacer content can be considered as a powerful and practical discriminatory method for subtyping of
Language	English
Publishing date	2023-09-07
Publishing country	Iran
Document type	Journal Article
ISSN	2251-6093 ; 0304-4556
ISSN (online)	2251-6093
ISSN	0304-4556
DOI	10.18502/ijph.v52i8.13415
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