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  1. Article: [No title information]

    Pot, Caroline

    Revue medicale suisse

    2024  Volume 20, Issue 858, Page(s) 163–165

    Title translation Traitements de la sclérose en plaques en 2024.
    MeSH term(s) Humans ; Multiple Sclerosis/therapy
    Language French
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2024.20.858.163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: [No title information]

    Pot, Caroline

    Revue medicale suisse

    2020  Volume 16, Issue 679, Page(s) 184–185

    Title translation Rôle de la nutrition et de la flore intestinale dans les maladies autoimmunes - Que sait-on vraiment ? Représentation et connaissances scientifiques.
    MeSH term(s) Autoimmune Diseases/microbiology ; Gastrointestinal Microbiome ; Health Knowledge, Attitudes, Practice ; Humans ; Nutritional Status
    Language French
    Publishing date 2020-01-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Implication of Oxysterols and Phytosterols in Aging and Human Diseases.

    Vigne, Solenne / Pot, Caroline

    Advances in experimental medicine and biology

    2023  Volume 1440, Page(s) 231–260

    Abstract: Cholesterol is easily oxidized and can be transformed into numerous oxidation products, among which oxysterols. Phytosterols are plant sterols related to cholesterol. Both oxysterols and phytosterols can have an impact on human health and diseases ... ...

    Abstract Cholesterol is easily oxidized and can be transformed into numerous oxidation products, among which oxysterols. Phytosterols are plant sterols related to cholesterol. Both oxysterols and phytosterols can have an impact on human health and diseases.Cholesterol is a member of the sterol family that plays essential roles in biological processes, including cell membrane stability and myelin formation. Cholesterol can be metabolized into several molecules including bile acids, hormones, and oxysterols. On the other hand, phytosterols are plant-derived compounds structurally related to cholesterol, which can also have an impact on human health. Here, we review the current knowledge about the role of oxysterols and phytosterols on human health and focus on the impact of their pathways on diseases of the central nervous system (CNS), autoimmune diseases, including inflammatory bowel diseases (IBD), vascular diseases, and cancer in both experimental models and human studies. We will first discuss the implications of oxysterols and then of phytosterols in different human diseases.
    MeSH term(s) Humans ; Phytosterols ; Oxysterols/metabolism ; Cholesterol ; Sterols ; Autoimmune Diseases
    Chemical Substances Phytosterols ; Oxysterols ; Cholesterol (97C5T2UQ7J) ; Sterols
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-43883-7_12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3192: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Einzelsignatur: Show issues

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  4. Article ; Online: Closing the scissor-shaped curve: Strategies to promote gender equality in academia.

    Joyce, Johanna A / Masina, Slavica / Michalik, Liliane / Pot, Caroline / Sempoux, Christine / Amati, Francesca

    Cell

    2024  Volume 187, Issue 6, Page(s) 1335–1342

    Abstract: Gender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reaching leadership positions. This commentary discusses ... ...

    Abstract Gender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reaching leadership positions. This commentary discusses the "scissor-shaped curve" and examines effective strategies to fix it, including data-driven initiatives that we have implemented at our university.
    MeSH term(s) Humans ; Female ; Gender Equity ; Academia ; Leadership ; Universities
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2024.01.050
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1167: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 58: Show issues

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  5. Article: Traitements de la sclérose en plaques : mise à jour.

    Uginet, Marjolaine / Lefeuvre, Lucie / Lerusse, Julien / Pot, Caroline / Du Pasquier, Renaud / Lalive, Patrice H

    Revue medicale suisse

    2024  Volume 20, Issue 871, Page(s) 837–842

    Abstract: The management of multiple sclerosis (MS) has undergone a veritable revolution in recent years, with the arrival of highly effective treatments. In some cases, therapeutic discussions even precede the first clinical signs of the disease. The aim of this ... ...

    Title translation Treatments for multiple sclerosis: update.
    Abstract The management of multiple sclerosis (MS) has undergone a veritable revolution in recent years, with the arrival of highly effective treatments. In some cases, therapeutic discussions even precede the first clinical signs of the disease. The aim of this review is to present the therapeutic arsenal of progression-preventing treatments available in 2024 for MS, with anti-CD20 antibodies taking pride of place, also available for certain progressive forms of MS. The use of these immunosuppressants requires in-depth knowledge of their mechanisms of action, in order to understand their risks, such as the occurrence of opportunistic infections.
    MeSH term(s) Humans ; Multiple Sclerosis/therapy ; Multiple Sclerosis/drug therapy ; Immunosuppressive Agents/therapeutic use ; Disease Progression
    Chemical Substances Immunosuppressive Agents
    Language French
    Publishing date 2024-04-26
    Publishing country Switzerland
    Document type Journal Article ; Review ; English Abstract
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2024.20.871.837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Maladie du spectre des anticorps anti-MOG.

    Lerusse, Julien / Uginet, Marjolaine / Théaudin, Marie / Bernard-Valnet, Raphaël / Pot, Caroline / Lalive, Patrice H

    Revue medicale suisse

    2024  Volume 20, Issue 871, Page(s) 828–832

    Abstract: Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease (MOGAD) is an autoimmune disease responsible for demyelination of the central nervous system that can occur in adults or children. Overlapping phenotypes between MOGAD, multiple sclerosis ( ... ...

    Title translation Anti-MOG associated disease.
    Abstract Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease (MOGAD) is an autoimmune disease responsible for demyelination of the central nervous system that can occur in adults or children. Overlapping phenotypes between MOGAD, multiple sclerosis (MS) and neuromyelitis optica spectrum disease (NMOSD) have been described. The diagnostic criteria for MOGAD were proposed by a panel of international experts and published in 2023. Defining clinical, biological and imaging characteristics specific to this entity helps to improve diagnostic specificity. In this article, we present the clinical characteristics suggestive of MOGAD and discuss the importance of the antibody detection method and therapeutic management.
    MeSH term(s) Humans ; Myelin-Oligodendrocyte Glycoprotein/immunology ; Neuromyelitis Optica/diagnosis ; Neuromyelitis Optica/immunology ; Autoantibodies/immunology ; Autoantibodies/blood ; Multiple Sclerosis/diagnosis ; Multiple Sclerosis/immunology ; Adult ; Child ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/immunology
    Chemical Substances Myelin-Oligodendrocyte Glycoprotein ; Autoantibodies
    Language French
    Publishing date 2024-04-26
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2024.20.871.828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Troubles cognitifs dans la sclérose en plaques : quand y penser ?

    Perrenoud, Matthieu / Blosch, Laurène / Du Pasquier, Renaud / Pot, Caroline

    Revue medicale suisse

    2023  Volume 19, Issue 824, Page(s) 791–793

    Abstract: Cognitive disorders are present in 30 to 45% of relapsing-remitting forms of multiple sclerosis and in up to 50-75% of progressive forms. They bear a negative impact on the quality of life and predict an unfavorable disease progression. According to ... ...

    Title translation Cognitive impairment in multiple sclerosis: when to think about it?
    Abstract Cognitive disorders are present in 30 to 45% of relapsing-remitting forms of multiple sclerosis and in up to 50-75% of progressive forms. They bear a negative impact on the quality of life and predict an unfavorable disease progression. According to guidelines, screening based on objective measurement such as the Single Digit Modality Test (SDMT) should be performed at the time of diagnosis and then on an annual basis. Confirmation of diagnosis and management are performed in collaboration with neuropsychologists. Increased awareness from patients and healthcare professionals is important to ensure earlier management and prevent negative consequences on the patients professional and family life.
    MeSH term(s) Humans ; Multiple Sclerosis/complications ; Multiple Sclerosis/diagnosis ; Quality of Life ; Multiple Sclerosis, Relapsing-Remitting/diagnosis ; Multiple Sclerosis, Relapsing-Remitting/psychology ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Cognition Disorders/diagnosis ; Neuropsychological Tests
    Language French
    Publishing date 2023-05-03
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.824.791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: How Microbiota-Derived Metabolites Link the Gut to the Brain during Neuroinflammation.

    Rebeaud, Jessica / Peter, Benjamin / Pot, Caroline

    International journal of molecular sciences

    2022  Volume 23, Issue 17

    Abstract: Microbiota-derived metabolites are important molecules connecting the gut to the brain. Over the last decade, several studies have highlighted the importance of gut-derived metabolites in the development of multiple sclerosis (MS). Indeed, microbiota- ... ...

    Abstract Microbiota-derived metabolites are important molecules connecting the gut to the brain. Over the last decade, several studies have highlighted the importance of gut-derived metabolites in the development of multiple sclerosis (MS). Indeed, microbiota-derived metabolites modulate the immune system and affect demyelination. Here, we discuss the current knowledge about microbiota-derived metabolites implications in MS and in different mouse models of neuroinflammation. We focus on the main families of microbial metabolites that play a role during neuroinflammation. A better understanding of the role of those metabolites may lead to new therapeutical avenues to treat neuroinflammatory diseases targeting the gut-brain axis.
    MeSH term(s) Animals ; Brain/metabolism ; Gastrointestinal Microbiome ; Mice ; Microbiota ; Multiple Sclerosis/metabolism ; Neuroinflammatory Diseases
    Language English
    Publishing date 2022-09-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231710128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Traitements de la sclérose en plaques : quand les arrêter ?

    Bernard-Valnet, Raphaël / Lalive, Patrice H / Bréville, Gautier / Théaudin, Marie / Pot, Caroline / Du Pasquier, Renaud

    Revue medicale suisse

    2024  Volume 20, Issue 871, Page(s) 843–847

    Abstract: Aging in multiple sclerosis (MS) leads to altered clinical manifestations, where the pathophysiology shifts towards compartmentalized inflammation that drives clinical progression independent of relapse activity. Consequently, the effectiveness of ... ...

    Title translation Discontinuing disease-modifying therapies in multiple sclerosis.
    Abstract Aging in multiple sclerosis (MS) leads to altered clinical manifestations, where the pathophysiology shifts towards compartmentalized inflammation that drives clinical progression independent of relapse activity. Consequently, the effectiveness of disease-modifying therapies (DMTs) diminishes in older patients, coinciding with an elevated risk of adverse events. This raises the question of whether MS therapies should be discontinued after a certain age, which is often proposed for patients over 55 years. Studies on treatment discontinuation have shown a slight increase in disease activity, yet without significant disability progression. This suggests that the decision to stop DMTs should be discussed with older patients, considering existing comorbidities. Following the cessation of therapy, meticulous monitoring is essential.
    MeSH term(s) Humans ; Multiple Sclerosis/drug therapy ; Disease Progression ; Age Factors ; Middle Aged ; Withholding Treatment
    Language French
    Publishing date 2024-04-26
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2024.20.871.843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: How Microbiota-Derived Metabolites Link the Gut to the Brain during Neuroinflammation

    Jessica Rebeaud / Benjamin Peter / Caroline Pot

    International Journal of Molecular Sciences, Vol 23, Iss 10128, p

    2022  Volume 10128

    Abstract: Microbiota-derived metabolites are important molecules connecting the gut to the brain. Over the last decade, several studies have highlighted the importance of gut-derived metabolites in the development of multiple sclerosis (MS). Indeed, microbiota- ... ...

    Abstract Microbiota-derived metabolites are important molecules connecting the gut to the brain. Over the last decade, several studies have highlighted the importance of gut-derived metabolites in the development of multiple sclerosis (MS). Indeed, microbiota-derived metabolites modulate the immune system and affect demyelination. Here, we discuss the current knowledge about microbiota-derived metabolites implications in MS and in different mouse models of neuroinflammation. We focus on the main families of microbial metabolites that play a role during neuroinflammation. A better understanding of the role of those metabolites may lead to new therapeutical avenues to treat neuroinflammatory diseases targeting the gut–brain axis.
    Keywords neuroinflammation ; multiple sclerosis ; experimental autoimmune encephalomyelitis ; gut–brain axis ; microbiota-derived metabolites ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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