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  1. Article ; Online: Accelerate the elimination of rubella through supplementary immunisation activities in China.

    Chong, Ka Chun / Jia, Katherine Min

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 7, Page(s) 899–900

    MeSH term(s) China/epidemiology ; Humans ; Immunization ; Rubella/epidemiology ; Rubella/prevention & control ; Vaccination
    Language English
    Publishing date 2021-01-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30715-5
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    Zs.A 5743: Show issues Location:
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  2. Article ; Online: Inferring Incidence of Unreported SARS-CoV-2 Infections Using Seroprevalence of Open Reading Frame 8 Antigen, Hong Kong.

    Zhao, Shi / Mok, Chris Ka Pun / Tang, Yun Sang / Chen, Chunke / Sun, Yuanxin / Chong, Ka Chun / Hui, David S C

    Emerging infectious diseases

    2024  Volume 30, Issue 2, Page(s) 325–328

    Abstract: We tested seroprevalence of open reading frame 8 antigens to infer the number of unrecognized SARS-CoV-2 Omicron infections in Hong Kong during 2022. We estimate 33.6% of the population was infected, 72.1% asymptomatically. Surveillance and control ... ...

    Abstract We tested seroprevalence of open reading frame 8 antigens to infer the number of unrecognized SARS-CoV-2 Omicron infections in Hong Kong during 2022. We estimate 33.6% of the population was infected, 72.1% asymptomatically. Surveillance and control activities during large-scale outbreaks should account for potentially substantial undercounts.
    MeSH term(s) Humans ; Hong Kong/epidemiology ; Seroepidemiologic Studies ; COVID-19/epidemiology ; Incidence ; Open Reading Frames ; SARS-CoV-2
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid3002.231332
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  3. Article ; Online: Development and validation of a Chinese Drinking Expectancies Questionnaire for young adults: A Hong Kong study.

    Chan, Rufina H W / Dong, Dong / Chong, Ka-Chun / Kim, Jean H

    Drug and alcohol review

    2023  Volume 43, Issue 1, Page(s) 233–244

    Abstract: Introduction: Drinking expectancies, the perceived consequences of alcohol consumption, are noted to predict drinking behaviours. However, there is comparatively little research of drinking expectancies in non-Western populations. This study aimed to ... ...

    Abstract Introduction: Drinking expectancies, the perceived consequences of alcohol consumption, are noted to predict drinking behaviours. However, there is comparatively little research of drinking expectancies in non-Western populations. This study aimed to develop and validate a Chinese Drinking Expectancy Questionnaire (CDEQ-Adult) for Chinese young adults.
    Methods: Face and content validity were first assessed of items generated from literature review and previously conducted focus groups. Exploratory (EFA) and confirmatory factor analyses (CFA) were conducted with split-half samples from a random telephone survey that was conducted on Hong Kong Chinese adults between the ages of 18-34 (n = 675). The instrument's convergent validity and internal reliability were also examined.
    Results: The preliminary instrument items showed good content validity (Item Content Validity Index range: 0.8-1.0). The EFA yielded a 31-item, five-factor model consisting of five domains: Negative Consequences, Interpersonal Benefits, Increased Confidence, Health Benefits and Tension/Stress Reduction (variance explained 63.7%). The CFA revealed that the fit indices for the five-factor model using diagonal weighted least squares estimator were χ
    Discussion and conclusions: The CDEQ-Adult is a culturally relevant instrument for assessing drinking expectancies in Chinese young adults for use in future studies.
    MeSH term(s) Humans ; Young Adult ; Adolescent ; Adult ; Hong Kong ; Reproducibility of Results ; Surveys and Questionnaires ; Psychometrics ; Factor Analysis, Statistical
    Language English
    Publishing date 2023-08-11
    Publishing country Australia
    Document type Review ; Journal Article
    ZDB-ID 1080442-0
    ISSN 1465-3362 ; 0959-5236
    ISSN (online) 1465-3362
    ISSN 0959-5236
    DOI 10.1111/dar.13733
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  4. Article ; Online: Superspreading potential of SARS-CoV-2 Delta variants under intensive disease control measures in China.

    Zhao, Shi / Guo, Zihao / Chong, Marc Ka Chun / He, Daihai / Wang, Maggie H

    Journal of travel medicine

    2022  Volume 29, Issue 3

    MeSH term(s) COVID-19/prevention & control ; China/epidemiology ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-03-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taac025
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  5. Article ; Online: Infection rate in Guangzhou after easing the zero-COVID policy: seroprevalence results to ORF8 antigen.

    Huang, Junyuan / Zhao, Shi / Chong, Ka Chun / Zhou, Yingchun / Lu, Weiguo / Fang, Fang / Cheung, Peter Pak Hang / Lai, Kiu Cheung / Hui, David Sc / Mok, Chris Ka Pun

    The Lancet. Infectious diseases

    2023  Volume 23, Issue 4, Page(s) 403–404

    MeSH term(s) Humans ; COVID-19/epidemiology ; Seroepidemiologic Studies ; SARS-CoV-2 ; Viral Proteins
    Chemical Substances Viral Proteins
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00112-3
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  6. Article ; Online: Superspreading potential of infection seeded by the SARS-CoV-2 Omicron BA.1 variant in South Korea.

    Guo, Zihao / Zhao, Shi / Ryu, Sukhyun / Mok, Chris Ka Pun / Hung, Chi Tim / Chong, Ka Chun / Yeoh, Eng Kiong

    The Journal of infection

    2022  Volume 85, Issue 3, Page(s) e77–e79

    MeSH term(s) COVID-19 ; Humans ; Republic of Korea/epidemiology ; SARS-CoV-2
    Language English
    Publishing date 2022-06-01
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2022.05.041
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  7. Article ; Online: Exposure to Neighborhood Greenness and Hypertension Incidence in Adults: A Longitudinal Cohort Study in Taiwan.

    Zeng, Yi Qian / Chong, Ka Chun / Chang, Ly-Yun / Liang, Xue / Guo, Li-Hao / Dong, Guanghui / Tam, Tony / Lao, Xiang Qian

    Environmental health perspectives

    2024  Volume 132, Issue 3, Page(s) 37001

    Abstract: Background: There are few studies on the health effects of long-term exposure to neighborhood greenness in a longitudinal setting, especially in Asian countries with high population densities.: Objectives: This study investigates the association ... ...

    Abstract Background: There are few studies on the health effects of long-term exposure to neighborhood greenness in a longitudinal setting, especially in Asian countries with high population densities.
    Objectives: This study investigates the association between long-term exposure to neighborhood greenness and hypertension among adults in Taiwan.
    Methods: We selected 125,537 participants (
    Results: Compared with living in areas within the first quartile of neighborhood greenness, living in areas within the second, third, and fourth quartiles of neighborhood greenness was found to be associated with a lower risk of hypertension, with hazard ratios (HRs) and 95% confidence intervals (CIs) of 0.95 (95% CI: 0.91, 1.00), 0.95 (95% CI: 0.90, 0.99), and 0.93 (95% CI: 0.88, 0.97), respectively. Each 0.1-unit increase in the NDVI was associated with a 24% lower risk of developing hypertension (
    Discussion: Our findings suggest the protective effects of neighborhood greenness on hypertension development, especially in males and well-educated individuals. Our results reinforced the importance of neighborhood greenness for supporting health. https://doi.org/10.1289/EHP13071.
    MeSH term(s) Male ; Adult ; Humans ; Longitudinal Studies ; Taiwan/epidemiology ; Incidence ; Cohort Studies ; Hypertension/epidemiology ; Air Pollution ; China/epidemiology ; Particulate Matter
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP13071
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    Zs.B 1360: Show issues Location:
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  8. Article ; Online: Metabolic dysfunction-associated profiles and subsequent site-specific risk of obesity-related cancers among Chinese patients with diabetes: a retrospective cohort study.

    Yau, Sarah Tsz Yui / Leung, Eman / Wong, Martin Chi Sang / Hung, Chi Tim / Chong, Ka Chun / Lee, Albert / Yeoh, Eng Kiong

    BMJ open

    2024  Volume 14, Issue 4, Page(s) e082414

    Abstract: Objectives: To compare metabolic dysfunction-associated profiles between patients with diabetes who developed different obesity-related site-specific cancers and those who remained free of cancer during follow-up.: Design: Retrospective cohort study.! ...

    Abstract Objectives: To compare metabolic dysfunction-associated profiles between patients with diabetes who developed different obesity-related site-specific cancers and those who remained free of cancer during follow-up.
    Design: Retrospective cohort study.
    Setting: Public general outpatient clinics in Hong Kong.
    Participants: Patients with diabetes without a history of malignancy (n=391 921).
    Primary outcome measures: The outcomes of interest were diagnosis of site-specific cancers (colon and rectum, liver, pancreas, bladder, kidney and stomach) during follow-up. Cox proportional hazards regression was applied to assess the associations between metabolic dysfunction and other clinical factors with each site-specific cancer.
    Results: Each 0.1 increase in waist-to-hip ratio was associated with an 11%-35% elevated risk of colorectal, bladder and liver cancers. Each 1% increase in glycated haemoglobin was linked to a 4%-9% higher risk of liver and pancreatic cancers. While low-density lipoprotein cholesterol and triglycerides were inversely associated with the risk of liver and pancreatic cancers, high-density lipoprotein cholesterol was negatively associated with pancreatic, gastric and kidney cancers, but positively associated with liver cancer. Furthermore, liver cirrhosis was linked to a 56% increased risk of pancreatic cancer. No significant association between hypertension and cancer risk was found.
    Conclusions: Metabolic dysfunction-associated profiles contribute to different obesity-related cancer outcomes differentially among patients with diabetes. This study may provide evidence to help identify cancer prevention targets during routine diabetes care.
    MeSH term(s) Humans ; Retrospective Studies ; Diabetes Mellitus/epidemiology ; Obesity/complications ; Hong Kong/epidemiology ; Kidney Neoplasms/epidemiology ; Kidney Neoplasms/etiology ; Cholesterol ; Pancreatic Neoplasms/etiology ; Pancreatic Neoplasms/complications ; Risk Factors
    Chemical Substances Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-082414
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  9. Article ; Online: The role of older adult-focused social vulnerability on the relationship between temperature and emergency department attendance in a subtropical Asian city.

    Ho, Janice Ying-En / Lai, Eric Tc / Chau, Pui Hing / Chong, Ka Chun / Woo, Jean

    Archives of gerontology and geriatrics

    2023  Volume 117, Page(s) 105195

    Abstract: Purpose: Older adults exhibit a wide range of capabilities and vulnerabilities that affect their capacity to respond to heat. This study analysed the associations between hot temperatures and Accident & Emergency (A&E) attendance taking into account ... ...

    Abstract Purpose: Older adults exhibit a wide range of capabilities and vulnerabilities that affect their capacity to respond to heat. This study analysed the associations between hot temperatures and Accident & Emergency (A&E) attendance taking into account older adult-focused social vulnerability.
    Methods: Daily A&E attendance data of Young-old (65-74) and Old-old (75+) was obtained for Hong Kong 2010-2019 hot seasons and stratified into three Social Vulnerability Index (SVI) groups (Low, Moderate, High). Mean temperature (lag 0-2) was analysed on A&E attendance at each SVI using Generalized Additive Models and Distributed Lag Non-linear Models.
    Results: High temperatures were associated with increased same-day (lag 0) relative risk (RR) of A&E attendance for Young-old and Old-old in High SVI districts, with RR being 1.024 (95 % CI: 1.011, 1.037) and 1.036 (95 % CI: 1.018, 1.053), respectively. The Old-old living in Moderate and Low SVI districts also demonstrated increased RR of 1.037 (95 % CI: 1.028, 1.047) and 1.022 (95 % CI: 1.009, 1.036), respectively. Fewer emergency visits were found on the subsequent day (lag 1) of hot temperatures.
    Conclusions: Older adults, both young-old and old-old, living in districts with higher social vulnerability tended to have increased risk of A&E attendance associated with same-day high temperature. With climate change and rapidly aging population, cities should prepare to meet needs of more vulnerable older adults in extreme heat.
    MeSH term(s) Humans ; Aged ; Temperature ; Cities ; Social Vulnerability ; Hot Temperature ; Emergency Service, Hospital
    Language English
    Publishing date 2023-09-11
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2023.105195
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    Zs.A 1729: Show issues Location:
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  10. Article ; Online: Hericium erinaceus

    Chau, Sze Chun / Chong, Pit Shan / Jin, Hongkai / Tsui, Ka Chun / Khairuddin, Sharafuddin / Tse, Anna Chung Kwan / Lew, Sze Yuen / Tipoe, George Lim / Lee, Chi Wai / Fung, Man-Lung / Wong, Kah Hui / Lim, Lee Wei

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects ... ...

    Abstract Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects of
    MeSH term(s) Rats ; Animals ; Cerebellar Ataxia/drug therapy ; Cerebellar Ataxia/genetics ; Cerebellar Ataxia/metabolism ; Hericium ; Disease Models, Animal ; Anti-Inflammatory Agents/therapeutic use
    Chemical Substances Anti-Inflammatory Agents
    Language English
    Publishing date 2023-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076089
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