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Article ; Online: Flavin Mononucleotide-Dependent l-Lactate Dehydrogenases: Expanding the Toolbox of Enzymes for l-Lactate Biosensors.

Tsvik, Lidiia / Steiner, Beate / Herzog, Peter / Haltrich, Dietmar / Sützl, Leander

ACS omega

2022 Volume 7, Issue 45, Page(s) 41480–41492

Abstract: The development of L-lactate biosensors has been hampered in recent years by the lack ... of availability and knowledge about a wider range and diversity of L-lactate-oxidizing enzymes that can be used ... as bioelements in these sensors. For decades, L-lactate oxidase of ...

Abstract	The development of L-lactate biosensors has been hampered in recent years by the lack of availability and knowledge about a wider range and diversity of L-lactate-oxidizing enzymes that can be used as bioelements in these sensors. For decades, L-lactate oxidase of
Language	English
Publishing date	2022-10-31
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.2c05257
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: L-band vegetation optical depth as an indicator of plant water potential in a temperate deciduous forest stand

N. M. Holtzman / L. D. L. Anderegg / S. Kraatz / A. Mavrovic / O. Sonnentag / C. Pappas / M. H. Cosh / A. Langlois / T. Lakhankar / D. Tesser / N. Steiner / A. Colliander / A. Roy / A. G. Konings

Biogeosciences, Vol 18, Pp 739-

2021 Volume 753

Abstract: ... remote sensing to test the link between remotely sensed VOD and plant water potential. We placed an L-band ...

Abstract	Vegetation optical depth (VOD) retrieved from microwave radiometry correlates with the total amount of water in vegetation, based on theoretical and empirical evidence. Because the total amount of water in vegetation varies with relative water content (as well as with biomass), this correlation further suggests a possible relationship between VOD and plant water potential, a quantity that drives plant hydraulic behavior. Previous studies have found evidence for that relationship on the scale of satellite pixels tens of kilometers across, but these comparisons suffer from significant scaling error. Here we used small-scale remote sensing to test the link between remotely sensed VOD and plant water potential. We placed an L-band radiometer on a tower above the canopy looking down at red oak forest stand during the 2019 growing season in central Massachusetts, United States. We measured stem xylem and leaf water potentials of trees within the stand and retrieved VOD with a single-channel algorithm based on continuous radiometer measurements and measured soil moisture. VOD exhibited a diurnal cycle similar to that of leaf and stem water potential, with a peak at approximately 05:00 eastern daylight time (UTC − 4). VOD was also positively correlated with both the measured dielectric constant and water potentials of stem xylem over the growing season. The presence of moisture on the leaves did not affect the observed relationship between VOD and stem water potential. We used our observed VOD–water-potential relationship to estimate stand-level values for a radiative transfer parameter and a plant hydraulic parameter, which compared well with the published literature. Our findings support the use of VOD for plant hydraulic studies in temperate forests.
Keywords	Ecology ; QH540-549.5 ; Life ; QH501-531 ; Geology ; QE1-996.5
Subject code	580
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Copernicus Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: L-band vegetation optical depth as an indicator of plant water potential in a temperate deciduous forest stand

Holtzman, Nataniel M. / Anderegg, Leander D. L. / Kraatz, Simon / Mavrovic, Alex / Sonnentag, Oliver / Pappas, Christoforos / Cosh, Michael H. / Langlois, Alexandre / Lakhankar, Tarendra / Tesser, Derek / Steiner, Nicholas / Colliander, Andreas / Roy, Alexandre / Konings, Alexandra G.

eISSN: 1726-4189

2021

Abstract: ... remote sensing to test the link between remotely sensed VOD and plant water potential. We placed an L-band ...

Abstract	Vegetation optical depth (VOD) retrieved from microwave radiometry correlates with the total amount of water in vegetation, based on theoretical and empirical evidence. Because the total amount of water in vegetation varies with relative water content (as well as with biomass), this correlation further suggests a possible relationship between VOD and plant water potential, a quantity that drives plant hydraulic behavior. Previous studies have found evidence for that relationship on the scale of satellite pixels tens of kilometers across, but these comparisons suffer from significant scaling error. Here we used small-scale remote sensing to test the link between remotely sensed VOD and plant water potential. We placed an L-band radiometer on a tower above the canopy looking down at red oak forest stand during the 2019 growing season in central Massachusetts, United States. We measured stem xylem and leaf water potentials of trees within the stand and retrieved VOD with a single-channel algorithm based on continuous radiometer measurements and measured soil moisture. VOD exhibited a diurnal cycle similar to that of leaf and stem water potential, with a peak at approximately 05:00 eastern daylight time (UTC − 4). VOD was also positively correlated with both the measured dielectric constant and water potentials of stem xylem over the growing season. The presence of moisture on the leaves did not affect the observed relationship between VOD and stem water potential. We used our observed VOD–water-potential relationship to estimate stand-level values for a radiative transfer parameter and a plant hydraulic parameter, which compared well with the published literature. Our findings support the use of VOD for plant hydraulic studies in temperate forests.
Subject code	580
Language	English
Publishing date	2021-02-01
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Vivre l’anarchie ici et maintenant

Anne Steiner

Cahiers d’histoire. , Vol 133, Pp 43-

milieux libres et colonies libertaires à la Belle Époque

2016 Volume 58

Abstract: ... testent la validité de l’hypothèse communiste (travailler et produire en dehors de tout rapport d ... utopistes, beaucoup plus souples dans la forme, plus respectueux de l’individualité et plus modestes ... quant aux fins poursuivies. Il s’agit moins, en effet, de former les cellules de l’humanité future ...

Abstract	Dans un contexte de forte mobilisation ouvrière (plus de 1000 grèves par an en moyenne entre 1905 et 1912), des militants anarchistes, sceptiques quant aux possibilités de grève générale et d’insurrection, testent la validité de l’hypothèse communiste (travailler et produire en dehors de tout rapport d’exploitation et de domination) dans le cadre de communautés de vie et de travail appelées alors « milieux libres ». Les dispositifs qu’ils inventent sont très différents de ceux qu’ont imaginés les socialistes utopistes, beaucoup plus souples dans la forme, plus respectueux de l’individualité et plus modestes quant aux fins poursuivies. Il s’agit moins, en effet, de former les cellules de l’humanité future que de se donner les moyens, en échappant au salariat, de vivre ici et maintenant en anarchiste.
Keywords	Anarchie ; utopie ; milieux libres ; communauté ; colonie ; individualité ; History (General) and history of Europe ; D
Language	French
Publishing date	2016-10-01T00:00:00Z
Publisher	Association Paul Langevin
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Vivre l’anarchie ici et maintenant

Anne Steiner

Cahiers d’histoire., Vol 133, Pp 43-

milieux libres et colonies libertaires à la Belle Époque

2016 Volume 58

Abstract	Dans un contexte de forte mobilisation ouvrière (plus de 1000 grèves par an en moyenne entre 1905 et 1912), des militants anarchistes, sceptiques quant aux possibilités de grève générale et d’insurrection, testent la validité de l’hypothèse communiste (travailler et produire en dehors de tout rapport d’exploitation et de domination) dans le cadre de communautés de vie et de travail appelées alors « milieux libres ». Les dispositifs qu’ils inventent sont très différents de ceux qu’ont imaginés les socialistes utopistes, beaucoup plus souples dans la forme, plus respectueux de l’individualité et plus modestes quant aux fins poursuivies. Il s’agit moins, en effet, de former les cellules de l’humanité future que de se donner les moyens, en échappant au salariat, de vivre ici et maintenant en anarchiste.
Keywords	Anarchie ; utopie ; milieux libres ; communauté ; colonie ; individualité ; History (General) and history of Europe ; D
Language	French
Publishing date	2016-10-01T00:00:00Z
Publisher	Association Paul Langevin
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: L-band vegetation optical depth as an indicator of plant water potential in a temperate deciduous forest stand

Holtzman, Nataniel / Anderegg, Leander D. L. / Kraatz, Simon / Mavrovic, Alex / Sonnentag, Oliver / Pappas, Christoforos / Cosh, Michael H. / Langlois, Alexandre / Lakhankar, Tarendra / Tesser, Derek / Steiner, Nicholas / Colliander, Andreas / Roy, Alexandre / Konings, Alexandra G.

eISSN: 1726-4189

2020

Abstract: ... remote sensing to test the link between remotely sensed VOD and plant water potential. We placed an L-band ...

Abstract	Vegetation optical depth (VOD) retrieved from microwave radiometry correlates with the total amount of water in vegetation, based on theoretical and empirical evidence. Because the total amount of water in vegetation varies with relative water content (as well as with biomass), this correlation further suggests a possible relationship between VOD and plant water potential, a quantity that drives plant hydraulic behavior. Previous studies have found evidence for that relationship on the scale of satellite pixels tens of kilometers across, but these comparisons suffer from significant scaling error. Here we used small-scale remote sensing to test the link between remotely sensed VOD and plant water potential. We placed an L-band radiometer on a tower above the canopy looking down at red oak forest stand during the 2019 growing season in central Massachusetts, United States. We measured stem xylem and leaf water potentials of trees within the stand, and retrieved VOD with a single-channel algorithm based on continuous radiometer measurements and measured soil moisture. VOD exhibited a diurnal cycle similar to that of leaf and stem water potential, with a peak at approximately 5 AM. VOD was also positively correlated with both the measured dielectric constant and water potentials of stem xylem over the growing season. The presence of moisture on the leaves did not affect the observed relationship between VOD and stem water potential. We used our observed VOD-water potential relationship to estimate stand-level values for a radiative transfer parameter and a plant hydraulic parameter, which compared well with the published literature. Our findings support the use of VOD for plant hydraulic studies in temperate forests.
Subject code	580
Language	English
Publishing date	2020-10-16
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Above and belowground traits impacting transpiration decline during soil drying in 48 maize (Zea mays L.) genotypes

Koehler, Tina / Schaum, Carolin / Tung, Shu-Yin / Steiner, Franziska / Tyborski, Nicolas / Wild, Andreas J. / Akale, Asegidew / Pausch, Johanna / Lueders, Tillmann / Wolfrum, Sebastian / Mueller, Carsten / Vidal, Alix / Vahl, Wouter / Groth, Jennifer / Eder, Barbara / Ahmed, Mutez / Carminati, Andrea

Annals of Botany

2023 Volume 131, Issue 2

Abstract: ... We investigate the response of 48 contrasting maize (Zea mays L.) genotypes to soil drying, utilizing a novel ...

Abstract	Background and Aim: Stomatal regulation allows plants to promptly respond to water stress. However, our understanding of the impact of above and belowground hydraulic traits on stomatal regulation remains incomplete. The objective of this study was to investigate how key plant hydraulic traits impact transpiration of maize during soil drying. We hypothesize that stomatal response to soil drying is related to a loss in soil hydraulic conductivity at the root-soil interface, which in turn depends on plant hydraulic traits. Methods: We investigate the response of 48 contrasting maize (Zea mays L.) genotypes to soil drying, utilizing a novel phenotyping facility. In this context, we measure the relationship between leaf water potential, soil water potential, soil water content and transpiration, as well as root, rhizosphere and aboveground plant traits. Key Results: Genotypes differed in their responsiveness to soil drying. The critical soil water potential at which plants started decreasing transpiration was related to a combination of above- and belowground traits: genotypes with a higher maximum transpiration and plant hydraulic conductance as well as a smaller root and rhizosphere system closed stomata at less negative soil water potentials. Conclusions: Our results demonstrate the importance of belowground hydraulics for stomatal regulation and hence drought responsiveness during soil drying. Furthermore, this finding supports the hypothesis that stomata start to close when soil hydraulic conductivity drops at the root-soil interface.
Keywords	Life Science
Language	English
Publishing country	nl
Document type	Article ; Online
ZDB-ID	1461328-1
ISSN	1095-8290 ; 0305-7364
ISSN (online)	1095-8290
ISSN	0305-7364
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Thesis: Strukturanalyse und biogeochemische Prozessaufklärung am Beispiel zweier unterschiedlich depositionsbelasteter Kiefernforstökosysteme (Pinus sylvestris L.) des nordostdeutschen Tieflandes

Steiner, Andreas J. K.

(Cottbuser Schriften zu Bodenschutz und Rekultivierung ; 36)

2006

Author's details	Andreas J. K. Steiner
Series title	Cottbuser Schriften zu Bodenschutz und Rekultivierung ; 36
Collection
Keywords	Deutschland ; Kiefernwald ; Luftverunreinigender Stoff ; Deposition ; Forstökologie
Subject	Ablagerung ; Deposition ; Luftfremder Stoff ; Luftschadstoff ; Luft ; Pinetum sylvestris ; Kiefer
Language	German
Size	XIX, 414 S. : Ill., graph. Darst.
Publisher	Brandenburgische Techn. Univ
Publishing place	Cottbus
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Cottbus, Techn. Univ., Diss., 2006
Note	Zsfassung in engl. Sprache
HBZ-ID	HT014810106
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
068/1140	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: N-Thio-β-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.

Martelli, Giulia / Pessatti, Tomas Bohn / Steiner, Eva Maria / Cirillo, Martina / Caso, Carolina / Bisognin, Francesco / Landreh, Michael / Monte, Paola Dal / Giacomini, Daria / Schnell, Robert

Cell chemical biology

2021 Volume 28, Issue 9, Page(s) 1321–1332.e5

Abstract: ... remodeling. Novel N-thio-β-lactams were designed, synthesized, and characterized on the L,D-transpeptidase-2 ...

Abstract	Effective treatment of tuberculosis is frequently hindered by the emerging antimicrobial resistance of Mycobacterium tuberculosis. The present study evaluates monocyclic β-lactam compounds targeting the mycobacterial cell wall remodeling. Novel N-thio-β-lactams were designed, synthesized, and characterized on the L,D-transpeptidase-2, a validated target in M. tuberculosis. The candidates were evaluated in biochemical assays identifying five compounds presenting target-specific kinetic constants equal or superior to meropenem, a carbapenem currently considered for tuberculosis therapy. Mass spectrometry in line with the crystal structures of five target-ligand complexes revealed that the N-thio-β-lactams act via an unconventional mode of adduct formation, transferring the thio-residues from the lactam ring to the active-site cysteine of Ldt
MeSH term(s)	Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial/drug effects ; Microbial Sensitivity Tests ; Molecular Structure ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/enzymology ; Peptidyl Transferases/antagonists & inhibitors ; Peptidyl Transferases/metabolism ; beta-Lactams/chemical synthesis ; beta-Lactams/chemistry ; beta-Lactams/pharmacology
Chemical Substances	Anti-Bacterial Agents ; beta-Lactams ; Peptidyl Transferases (EC 2.3.2.12)
Language	English
Publishing date	2021-04-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2451-9448
ISSN (online)	2451-9448
DOI	10.1016/j.chembiol.2021.03.008
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Selective Regulation of 5-HT1B Serotonin Receptor Expression in the Striatum by Dopamine Depletion and Repeated L-DOPA Treatment: Relationship to L-DOPA-Induced Dyskinesias.

Padovan-Neto, Fernando E / Patterson, Santanna / F Voelkner, Nivea M / Altwal, Feras / Beverley, Joel A / West, Anthony R / Steiner, Heinz

Molecular neurobiology

2019 Volume 57, Issue 2, Page(s) 736–751

Abstract: ... depletion by 6-OHDA and subsequent treatment with L-DOPA (5 mg/kg; 4 weeks). Neither dopamine depletion nor ... L-DOPA treatment produced significant changes in 5-HT2C, 5-HT4, or 5-HT6 receptor expression ... throughout the striatum. Moreover, repeated L-DOPA treatment markedly further elevated 5-HT1B expression in the dopamine ...

Abstract	Dopamine and serotonin in the basal ganglia interact in a bidirectional manner. On the one hand, serotonin (5-HT) receptors regulate the effects of dopamine agonists on several levels, ranging from molecular signaling to behavior. These interactions include 5-HT receptor-mediated facilitation of dopamine receptor-induced gene regulation in striatal output pathways, which involves the 5-HT1B receptor and others. Conversely, there is evidence that dopamine action by psychostimulants regulates 5-HT1B receptor expression in the striatum. To further investigate the effects of dopamine and agonists on 5-HT receptors, we assessed the expression of 5-HT1B and other serotonin receptor subtypes in the striatum after unilateral dopamine depletion by 6-OHDA and subsequent treatment with L-DOPA (5 mg/kg; 4 weeks). Neither dopamine depletion nor L-DOPA treatment produced significant changes in 5-HT2C, 5-HT4, or 5-HT6 receptor expression in the striatum. In contrast, the 6-OHDA lesion caused a (modest) increase in 5-HT1B mRNA levels throughout the striatum. Moreover, repeated L-DOPA treatment markedly further elevated 5-HT1B expression in the dopamine-depleted striatum, an effect that was most robust in the sensorimotor striatum. A minor L-DOPA-induced increase in 5-HT1B expression was also seen in the intact striatum. These changes in 5-HT1B expression mimicked changes in the expression of neuropeptide markers (dynorphin, enkephalin mRNA) in striatal projection neurons. After repeated L-DOPA treatment, the severity of L-DOPA-induced dyskinesias and turning behavior was positively correlated with the increase in 5-HT1B expression in the associative, but not sensorimotor, striatum ipsilateral to the lesion, suggesting that associative striatal 5-HT1B receptors may play a role in L-DOPA-induced behavioral abnormalities.
MeSH term(s)	Animals ; Behavior, Animal ; Corpus Striatum/metabolism ; Dopamine/deficiency ; Dynorphins/metabolism ; Dyskinesia, Drug-Induced/genetics ; Dyskinesia, Drug-Induced/metabolism ; Dyskinesia, Drug-Induced/pathology ; Enkephalins/metabolism ; Gene Expression Regulation ; Levodopa/adverse effects ; Male ; Rats, Sprague-Dawley ; Receptor, Serotonin, 5-HT1B/metabolism ; Tyrosine 3-Monooxygenase/metabolism
Chemical Substances	Enkephalins ; Receptor, Serotonin, 5-HT1B ; Levodopa (46627O600J) ; Dynorphins (74913-18-1) ; Tyrosine 3-Monooxygenase (EC 1.14.16.2) ; Dopamine (VTD58H1Z2X)
Language	English
Publishing date	2019-08-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	645020-9
ISSN	1559-1182 ; 0893-7648
ISSN (online)	1559-1182
ISSN	0893-7648
DOI	10.1007/s12035-019-01739-x
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