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Article: Corrigendum: Enhanced intrinsic functional connectivity in the visual system of visual artist: implications for creativity.

Hong, Tzu-Yi / Yang, Ching-Ju / Shih, Chung-Heng / Fan, Sheng-Fen / Yeh, Tzu-Chen / Yu, Hsin-Yen / Chen, Li-Fen / Hsieh, Jen-Chuen

Frontiers in neuroscience

2023 Volume 17, Page(s) 1258987

Abstract: This corrects the article DOI: 10.3389/fnins.2023.1114771.]. ...

Abstract	[This corrects the article DOI: 10.3389/fnins.2023.1114771.].
Language	English
Publishing date	2023-08-24
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2023.1258987
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effect of home telehealth care on blood pressure control: A public healthcare centre model.

Lu, Ju-Fen / Chen, Ching-Min / Hsu, Chien-Yeh

Journal of telemedicine and telecare

2017 Volume 25, Issue 1, Page(s) 35–45

Abstract: Objective: This study aimed to evaluate the effectiveness of home telehealth care combined with case management by public health nurses, in improving blood pressure control in patients with hypertension.: Methods: This cohort study examined the data ... ...

Abstract	Objective: This study aimed to evaluate the effectiveness of home telehealth care combined with case management by public health nurses, in improving blood pressure control in patients with hypertension. Methods: This cohort study examined the data of patients with hypertension obtained from a telehealth service centre database, between July 2011- June 2012. Eligible patients were adults (≥40 years old) with both prehypertension and hypertension, living alone or in the remote suburbs of metropolitan areas. Demographic data were collected from 12 district public health centre in Taipei, Taiwan. Following enrolment, patients received an appropriate and validated home telehealth device kit for automatic blood pressure monitoring and automated modem via a telephone line or a desktop computer with Internet connection to enable data transmission between the patient's home and telehealth service centre. Patients were instructed to upload the measured data immediately every day. The study outcomes included blood pressure and home telehealth service utilisation. Results: Of the 432 patients recruited, 408 (94%) completed data collection. Linear regression analysis found an average 22.1 mm Hg reduction in systolic blood pressure after one year. The mean slope of systolic blood pressure was classified as decreased or non-decreased. An systolic blood pressure decreasing trend was observed in 52.2% patients, while 47.8% patients showed an increasing systolic blood pressure trend. Patients in the decreased systolic blood pressure group tended to be older ( p = 0. 0001), with a greater proportion of hypertension alarms ( p = 0. 001), improved self-blood pressure monitoring behaviour ( p = 0.009) and higher self-measured blood pressure monitoring frequency ( p = 0. 010). Patients in the decreased systolic blood pressure group had a higher self-measured blood pressure monitoring frequency (odds ratio = 0.95, 95% confidence interval, 0.91-0.99, p = 0. 013) than their counterparts. Conclusions: Home telehealth care combined with care management by public health nurses based in public health care centre was feasible and effective for improving blood pressure control among patients with hypertension. Further studies should conduct a thorough analysis of the cost-effectiveness of this intervention. A randomised controlled trial with a longer follow-up period is required to examine the effects of the improved home telehealth device kit on the care of patients with hypertension.
MeSH term(s)	Adult ; Aged ; Blood Pressure ; Blood Pressure Determination/statistics & numerical data ; Blood Pressure Monitoring, Ambulatory/statistics & numerical data ; Cardiovascular Diseases/prevention & control ; Cohort Studies ; Female ; Home Care Services/statistics & numerical data ; Humans ; Hypertension/prevention & control ; Internet ; Male ; Middle Aged ; Taiwan ; Telemedicine/statistics & numerical data
Language	English
Publishing date	2017-10-17
Publishing country	England
Document type	Journal Article
ZDB-ID	1340281-x
ISSN	1758-1109 ; 1357-633X
ISSN (online)	1758-1109
ISSN	1357-633X
DOI	10.1177/1357633X17734258
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Zs.A 4525: Show issues

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Article: Embodied metacognition as strengthened functional connection between neural correlates of metacognition and dance in dancers: exploring creativity implications.

Yang, Ching-Ju / Yu, Hsin-Yen / Hong, Tzu-Yi / Cheng, Li-Kai / Li, Wei-Chi / Yeh, Tzu-Chen / Chen, Li-Fen / Hsieh, Jen-Chuen

Frontiers in human neuroscience

2024 Volume 18, Page(s) 1347386

Abstract: Introduction: Dance education fosters embodied metacognition, enhancing student's creativity. This study examines the crucial role of functional connectivity (FC) between the neural correlates of metacognition (NCM) and dance (NCD) as the neurological ... ...

Abstract	Introduction: Dance education fosters embodied metacognition, enhancing student's creativity. This study examines the crucial role of functional connectivity (FC) between the neural correlates of metacognition (NCM) and dance (NCD) as the neurological foundation for dancers' embodied metacognition. The investigation also explores whether these consolidated FCs inform the general creativity in dancers. Methods: The research involved 29 dancers and 28 non-dancer controls. The study examined resting-state connections of the NCM through seed-based FC analysis. Correlation analyses were employed to investigate the connections between the targeted NCM-NCD FCs, initiated from the Results: Dancers demonstrated heightened FC between NCM and NCD compared to non-dancer controls. The targeted regions included the putamen, globus pallidus, posterior cerebellum, and anterior insula of NCD. The dancers exhibited higher originality scores. In dancers, the enhanced FC showed a negative correlation with originality and a positive correlation with flexibility. Conversely, the controls exhibited no significant correlations. Discussion: Extended dance training enhances the NCM-NCD connection signifying embodied metacognition. This interconnectedness may serve as the neural predisposition for fostering general creativity performance in dancers. Dancers with heightened levels of originality could leverage the relatively weaker NCM-NCD FCs to facilitate better integration and coordination of creative cognitive processes. Our findings suggest that the consolidated functional connections as sculpted by domain-specific training may inform general creativity.
Language	English
Publishing date	2024-02-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2425477-0
ISSN	1662-5161
ISSN	1662-5161
DOI	10.3389/fnhum.2024.1347386
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Article: Enhanced intrinsic functional connectivity in the visual system of visual artist: Implications for creativity.

Hong, Tzu-Yi / Yang, Ching-Ju / Shih, Chung-Heng / Fan, Sheng-Fen / Yeh, Tzu-Chen / Yu, Hsin-Yen / Chen, Li-Fen / Hsieh, Jen-Chuen

Frontiers in neuroscience

2023 Volume 17, Page(s) 1114771

Abstract: Introduction: This study sought to elucidate the cognitive traits of visual artists (VAs) from the perspective of visual creativity and the visual system (i.e., the most fundamental neural correlate).: Methods: We examined the local and long-distance ...

Abstract	Introduction: This study sought to elucidate the cognitive traits of visual artists (VAs) from the perspective of visual creativity and the visual system (i.e., the most fundamental neural correlate). Methods: We examined the local and long-distance intrinsic functional connectivity (FC) of the visual system to unravel changes in brain traits among VAs. Twenty-seven university students majoring in visual arts and 27 non-artist controls were enrolled. Results: VAs presented enhanced local FC in the right superior parietal lobule, right precuneus, left inferior temporal gyrus (ITG), left superior parietal lobule, left angular gyrus, and left middle occipital gyrus. VAs also presented enhanced FC with the ITG that targeted the visual area (occipital gyrus and cuneus), which appears to be associated with visual creativity. Discussion: The visual creativity of VAs was correlated with strength of intrinsic functional connectivity in the visual system. Learning-induced neuroplasticity as a trait change observed in VAs can be attributed to the macroscopic consolidation of consociated neural circuits that are engaged over long-term training in the visual arts and aesthetic experience. The consolidated network can be regarded as virtuoso-specific neural fingerprint.
Language	English
Publishing date	2023-02-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2023.1114771
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Article ; Online: Psychological distress among immigrant women who divorced: Resilience as a mediator.

Chen, I-Hui / Niu, Shu-Fen / Yeh, Yueh-Chen / Chen, I-Ju / Kuo, Shu-Fen

Archives of psychiatric nursing

2022 Volume 39, Page(s) 1–6

Abstract: Purpose: The purpose of this study was to investigate relationships among the demands of immigration, resilience, and psychological distress in divorced immigrant women, and determine the mediating effects of resilience on the relationship between ... ...

Abstract	Purpose: The purpose of this study was to investigate relationships among the demands of immigration, resilience, and psychological distress in divorced immigrant women, and determine the mediating effects of resilience on the relationship between demands of immigration and psychological distress. Design: The cross-sectional study included 117 women who had immigrated and married Taiwanese men but later got divorced. Methods: The Chinese health questionnaire-12 scale, the resilience scale-Chinese version, and the demands of immigration (DI) scale were used to measure in this study. A multiple regression and Sobel test were used to examine whether resilience mediated the relationship between demands of immigration and psychological distress. Findings: In this study, 47% of the divorced immigrant women were experiencing psychological distress, and 25.6% exhibited high levels of demands of immigration. Women with psychological distress had higher demand scores (t = 2.592, p = 0.011) and lower resilience scores (t = -3.965, p < 0.001) compared to women without psychological distress. The demands of immigration negatively predicted resilience (t = -3.050, p = 0.003). Finally, resilience mediated the association of demands of immigration with psychological distress (z = 2.497, p = 0.0125). Conclusions: Relationships among the demands of immigration, resilience, and psychological distress in divorced immigrant women were demonstrated in this study. Resilience played an important role in the relationship between demands of immigration and psychological distress. Clinical relevance: Tailored programs that foster resilience to reduce risks of demands of immigration and psychological distress in this vulnerable population should be developed.
MeSH term(s)	Cross-Sectional Studies ; Divorce ; Emigrants and Immigrants ; Emigration and Immigration ; Female ; Humans ; Male ; Psychological Distress ; Resilience, Psychological ; Stress, Psychological
Language	English
Publishing date	2022-02-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639197-7
ISSN	1532-8228 ; 0883-9417
ISSN (online)	1532-8228
ISSN	0883-9417
DOI	10.1016/j.apnu.2021.11.006
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Zs.A 2271: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Rejuvenating the Aging Heart by Enhancing the Expression of the

Yeh, Chi-Hsiao / Chou, Yi-Ju / Chu, Ting-Kuan / Tsai, Ting-Fen

International journal of molecular sciences

2021 Volume 22, Issue 21

Abstract: Aging is the major risk factor for cardiovascular disease, which is the leading cause of mortality worldwide among aging populations. ...

Abstract	Aging is the major risk factor for cardiovascular disease, which is the leading cause of mortality worldwide among aging populations.
MeSH term(s)	Aging/genetics ; Animals ; Autophagy/genetics ; Autophagy-Related Proteins/biosynthesis ; Autophagy-Related Proteins/genetics ; Cellular Senescence/genetics ; Endomyocardial Fibrosis/genetics ; Endomyocardial Fibrosis/physiopathology ; Heart/physiology ; Longevity/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Rejuvenation/physiology ; Sirtuins/metabolism ; Transcriptome/genetics
Chemical Substances	Autophagy-Related Proteins ; Nerve Tissue Proteins ; Noxp70 protein, mouse ; Sirtuins (EC 3.5.1.-)
Language	English
Publishing date	2021-10-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms222111487
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Article: Trait representation of embodied cognition in dancers pivoting on the extended mirror neuron system: a resting-state fMRI study.

Yang, Ching-Ju / Yu, Hsin-Yen / Hong, Tzu-Yi / Shih, Chung-Heng / Yeh, Tzu-Chen / Chen, Li-Fen / Hsieh, Jen-Chuen

Frontiers in human neuroscience

2023 Volume 17, Page(s) 1173993

Abstract: Introduction: Dance is an art form that integrates the body and mind through movement. Dancers develop exceptional physical and mental abilities that involve various neurocognitive processes linked to embodied cognition. We propose that dancers' primary ...

Abstract	Introduction: Dance is an art form that integrates the body and mind through movement. Dancers develop exceptional physical and mental abilities that involve various neurocognitive processes linked to embodied cognition. We propose that dancers' primary trait representation is movement-actuated and relies on the extended mirror neuron system (eMNS). Methods: A total of 29 dancers and 28 non-dancer controls were recruited. A hierarchical approach of intra-regional and inter-regional functional connectivity (FC) analysis was adopted to probe trait-like neurodynamics within and between regions in the eMNS during rest. Correlation analyses were employed to examine the associations between dance training, creativity, and the FC within and between different brain regions. Results: Within the eMNS, dancers exhibited increased intra-regional FC in various brain regions compared to non-dancers. These regions include the left inferior frontal gyrus, left ventral premotor cortex, left anterior insula, left posterior cerebellum (crus II), and bilateral basal ganglia (putamen and globus pallidus). Dancers also exhibited greater intrinsic inter-regional FC between the cerebellum and the core/limbic mirror areas within the eMNS. In dancers, there was a negative correlation observed between practice intensity and the intrinsic FC within the eMNS involving the cerebellum and basal ganglia. Additionally, FCs from the basal ganglia to the dorsolateral prefrontal cortex were found to be negatively correlated with originality in dancers. Discussion: Our results highlight the proficient communication within the cortical-subcortical hierarchy of the eMNS in dancers, linked to the automaticity and cognitive-motor interactions acquired through training. Altered functional couplings in the eMNS can be regarded as a unique neural signature specific to virtuoso dancers, which might predispose them for skilled dancing performance, perception, and creation.
Language	English
Publishing date	2023-07-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2425477-0
ISSN	1662-5161
ISSN	1662-5161
DOI	10.3389/fnhum.2023.1173993
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Article ; Online: NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia.

Chen, Chih-Wei / Su, Chi / Huang, Chang-Yu / Huang, Xuan-Rong / Cuili, Xiaojing / Chao, Tung / Fan, Chun-Hsiang / Ting, Cheng-Wei / Tsai, Yi-Wei / Yang, Kai-Chien / Yeh, Ti-Yen / Hsieh, Sung-Tsang / Chen, Yi-Ju / Feng, Yuxi / Hunter, Tony / Chang, Zee-Fen

Nature communications

2024 Volume 15, Issue 1, Page(s) 2264

Abstract: NME3 is a member of the nucleoside diphosphate kinase (NDPK) family localized on the mitochondrial outer membrane (MOM). Here, we report a role of NME3 in hypoxia-induced mitophagy dependent on its active site phosphohistidine but not the NDPK function. ... ...

Abstract	NME3 is a member of the nucleoside diphosphate kinase (NDPK) family localized on the mitochondrial outer membrane (MOM). Here, we report a role of NME3 in hypoxia-induced mitophagy dependent on its active site phosphohistidine but not the NDPK function. Mice carrying a knock-in mutation in the Nme3 gene disrupting NME3 active site histidine phosphorylation are vulnerable to ischemia/reperfusion-induced infarction and develop abnormalities in cerebellar function. Our mechanistic analysis reveals that hypoxia-induced phosphatidic acid (PA) on mitochondria is essential for mitophagy and the interaction of DRP1 with NME3. The PA binding function of MOM-localized NME3 is required for hypoxia-induced mitophagy. Further investigation demonstrates that the interaction with active NME3 prevents DRP1 susceptibility to MUL1-mediated ubiquitination, thereby allowing a sufficient amount of active DRP1 to mediate mitophagy. Furthermore, MUL1 overexpression suppresses hypoxia-induced mitophagy, which is reversed by co-expression of ubiquitin-resistant DRP1 mutant or histidine phosphorylatable NME3. Thus, the site-specific interaction with active NME3 provides DRP1 a microenvironment for stabilization to proceed the segregation process in mitophagy.
MeSH term(s)	Animals ; Mice ; Dynamins/genetics ; Dynamins/metabolism ; Histidine/metabolism ; Hypoxia ; Mitophagy/genetics ; Ubiquitination
Chemical Substances	Dynamins (EC 3.6.5.5) ; Histidine (4QD397987E) ; Nme3 protein, mouse (EC 2.7.4.6) ; Dnm1l protein, mouse (EC 3.6.5.5)
Language	English
Publishing date	2024-03-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-024-46385-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Discovery of a Biomarker Signature That Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Cross Talk.

Wu, I-Wen / Tsai, Tsung-Hsien / Lo, Chi-Jen / Chou, Yi-Ju / Yeh, Chi-Hsiao / Cheng, Mei-Ling / Lai, Chi-Chun / Sytwu, Huey-Kang / Tsai, Ting-Fen

Diabetes care

2022 Volume 45, Issue 6, Page(s) e102–e104

MeSH term(s)	Biomarkers ; Diabetes Mellitus ; Diabetic Nephropathies ; Humans
Chemical Substances	Biomarkers
Language	English
Publishing date	2022-05-12
Publishing country	United States
Document type	Research Support, Non-U.S. Gov't ; Letter
ZDB-ID	441231-x
ISSN	1935-5548 ; 0149-5992
ISSN (online)	1935-5548
ISSN	0149-5992
DOI	10.2337/dc22-0145
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Zs.A 1434: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 365: Show issues

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Article: Enhanced white matter fiber tract of the cortical visual system in visual artists: implications for creativity.

Hong, Tzu-Yi / Yang, Ching-Ju / Cheng, Li-Kai / Li, Wei-Chi / Tseng, Wen-Yih Isaac / Yeh, Tzu-Chen / Yu, Hsin-Yen / Chen, Li-Fen / Hsieh, Jen-Chuen

Frontiers in neuroscience

2023 Volume 17, Page(s) 1248266

Abstract: Introduction: This study aimed to examine the white matter characteristics of visual artists (VAs) in terms of visual creativity and the structural connectivity within the cortical visual system.: Methods: Diffusion spectrum imaging was utilized to ... ...

Abstract	Introduction: This study aimed to examine the white matter characteristics of visual artists (VAs) in terms of visual creativity and the structural connectivity within the cortical visual system. Methods: Diffusion spectrum imaging was utilized to examine the changes in white matter within the cortical visual system of a group of VAs ( Results: Our study uncovered that VAs demonstrated increased normalized quantitative anisotropy in specific brain regions, including the right inferior temporal gyrus and right lateral occipital gyrus, along with the corresponding white matter fiber tracts connecting these regions. These enhancements within the cortical visual system were also found to be correlated with measures of visual creativity obtained through psychological assessments. Discussion: The noted enhancement in the white matter within the cortical visual system of VAs, along with its association with visual creativity, is consistent with earlier research demonstrating heightened functional connectivity in the same system among VAs. Our study's findings suggest a link between the visual creativity of VAs and structural alterations within the brain's visual system.
Language	English
Publishing date	2023-10-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2023.1248266
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