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  1. Article: YouTube as a source of information for cryptococcal infection: A cross-sectional study.

    Liao, Kaijun / Feng, Zhiqiang / Lu, Dongli / Xia, Jianping / Wu, Zhaochun / Jiang, Zhenghua / Chen, Kun / Qiu, Hongqiang

    Digital health

    2024  Volume 10, Page(s) 20552076241249668

    Abstract: Objective: Immunocompromised individuals, particularly HIV patients, worldwide are at risk from cryptococcal infection. There are a number of videos of cryptococcal infection and more and more individuals may search these videos, but the quality of ... ...

    Abstract Objective: Immunocompromised individuals, particularly HIV patients, worldwide are at risk from cryptococcal infection. There are a number of videos of cryptococcal infection and more and more individuals may search these videos, but the quality of videos on YouTube is unclear. This study set out to assess the content and quality of YouTube videos regarding cryptococcal infection.
    Methods: The keywords "
    Results: A total of 46 videos were located, and the ratings provided by the two raters were identical. Our scoring algorithm determined that 54.3% (n = 25), 32.6% (n = 15) and 13.0% (n = 6) of the videos were poor, decent and exceptional, respectively. Regarding quality, no difference was identified between the various video categories. The global quality scale, number of views, days posted, content score and DISCERN showed a significant positive relationship.
    Conclusions: Professional individuals or healthcare organizations should be encouraged to submit high-quality videos for the expanding internet population, as only a small proportion of available videos had exceptional quality.
    Language English
    Publishing date 2024-04-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076241249668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Highly stretchable polyvinyl alcohol composite conductive hydrogel sensors reinforced by cellulose nanofibrils and liquid metal for information transmission.

    Hang, Tianyi / Chen, Yiming / Yin, Fuqiang / Shen, Jiahui / Li, Xiping / Li, Zhaochun / Zheng, Jiajia

    International journal of biological macromolecules

    2023  Volume 258, Issue Pt 1, Page(s) 128855

    Abstract: Conductive hydrogels have received widespread attention in the field of flexible sensors. However, a single network structure inside the hydrogel sensor usually makes it difficult to bear larger mechanical loadings, greatly limiting practical ... ...

    Abstract Conductive hydrogels have received widespread attention in the field of flexible sensors. However, a single network structure inside the hydrogel sensor usually makes it difficult to bear larger mechanical loadings, greatly limiting practical applications. Developing a recoverable conductive hydrogel sensor with high toughness and adaptability is still challenging. Herein, a high-performance polyvinyl alcohol (PVA)-based conductive composite hydrogel was constructed, assisted by green cellulose nanofibrils (CNFs), magnesium chloride (MgCl
    MeSH term(s) Polyvinyl Alcohol ; Cellulose ; Electric Conductivity ; Hydrogels ; Metals
    Chemical Substances polyvinyl alcohol hydrogel ; Polyvinyl Alcohol (9002-89-5) ; Cellulose (9004-34-6) ; Hydrogels ; Metals
    Language English
    Publishing date 2023-12-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.128855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Surveillance and analysis of avian influenza viruses in the external environment of poultry in Anqing City, Anhui Province

    WU Zhaochun / HUANG Xu / WANG Jinsheng / QIAN Yezhong / WANG Jin / CHEN Jiwen / LI Yuxin

    Shanghai yufang yixue, Vol 35, Iss 11, Pp 1058-

    2023  Volume 1062

    Abstract: ObjectiveTo determine the prevalence of avian influenza viruses in the external environment of poultry in Anqing City, Anhui Province, and provide scientific evidence for prevention and control of animal-derived influenza in humans.MethodsA total of 28 ... ...

    Abstract ObjectiveTo determine the prevalence of avian influenza viruses in the external environment of poultry in Anqing City, Anhui Province, and provide scientific evidence for prevention and control of animal-derived influenza in humans.MethodsA total of 28 farmers’ markets/farms in 10 counties (cities, districts) of Anqing City, Anhui Province, were selected as surveillance sites by simple random sampling strategy. Poultry faeces and other related samples were collected for 6 consecutive weeks. Real-time fluorescence quantitative PCR was used to examine the nucleic acids of influenza A virus. Subtypes H5, H7, and H9 of avian influenza virus were further tested in the positive samples.ResultsA total of 426 specimens were collected, among which 113 tested positive with a positive rate of 26.53%. Among the positive specimens, 104 were determined to be subtype H9, accounting for 92.04%. It did not significantly differ in the positive rate between the main and non-main urban areas (χ2<0.01, P>0.05) or among the specimens collected in different weeks (χ2=7.57, P>0.05). However, it significantly differed in the positive rate among the specimens collected in the third week and other weeks (χ2=6.89, P<0.05). Furthermore, among the different sampling sites, farms had the highest positive rate of 46.67%. Among the specimens from different sources, the surface-coated specimens from poultry cages had the highest positive rate of 34.78%.ConclusionAvian influenza viruses are prevalent in the external environment of poultry in Anqing City. It warrants strengthening the surveillance and risk assessment to reduce the virus transmission in the external environment and risk of human infection with animal-derived influenza.
    Keywords external environment ; avian influenza virus ; surveillance ; Medicine ; R
    Language Chinese
    Publishing date 2023-11-01T00:00:00Z
    Publisher Shanghai Preventive Medicine Association
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: High-performance composite elastomers with abundant heterostructures for enhanced electromagnetic wave absorption with ultrabroad bandwidth.

    Hang, Tianyi / Zheng, Jiajia / Zou, Yijie / Jiang, Shaohua / Zhao, Yuchen / Li, Zhaochun / Zhou, Lijie / Li, Xiping / Tong, Guoxiu / Chen, Yiming

    Journal of colloid and interface science

    2023  Volume 650, Issue Pt A, Page(s) 437–445

    Abstract: Two-dimensional (2D) MXene has attracted vast attention in electromagnetic wave absorption (EWA), but there remains a contradiction between maintaining impedance matching and enhancing dielectric loss. Herein, the multi-scale architectures of ecoflex/2D ... ...

    Abstract Two-dimensional (2D) MXene has attracted vast attention in electromagnetic wave absorption (EWA), but there remains a contradiction between maintaining impedance matching and enhancing dielectric loss. Herein, the multi-scale architectures of ecoflex/2D MXene (Ti
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2023.07.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Zero-Shot Position Debiasing for Large Language Models

    Liu, Zhongkun / Chen, Zheng / Zhang, Mengqi / Ren, Zhaochun / Chen, Zhumin / Ren, Pengjie

    2024  

    Abstract: Fine-tuning has been demonstrated to be an effective method to improve the domain performance of large language models (LLMs). However, LLMs might fit the dataset bias and shortcuts for prediction, leading to poor generation performance. Experimental ... ...

    Abstract Fine-tuning has been demonstrated to be an effective method to improve the domain performance of large language models (LLMs). However, LLMs might fit the dataset bias and shortcuts for prediction, leading to poor generation performance. Experimental result shows that LLMs are prone to exhibit position bias, i.e., leveraging information positioned at the beginning or end, or specific positional cues within the input. Existing works on mitigating position bias require external bias knowledge or annotated non-biased samples, which is unpractical in reality. In this work, we propose a zero-shot position debiasing (ZOE) framework to mitigate position bias for LLMs. ZOE leverages unsupervised responses from pre-trained LLMs for debiasing, thus without any external knowledge or datasets. To improve the quality of unsupervised responses, we propose a master-slave alignment (MSA) module to prune these responses. Experiments on eight datasets and five tasks show that ZOE consistently outperforms existing methods in mitigating four types of position biases. Besides, ZOE achieves this by sacrificing only a small performance on biased samples, which is simple and effective.

    Comment: 16 pages, 22 figures
    Keywords Computer Science - Computation and Language ; Computer Science - Artificial Intelligence ; Computer Science - Machine Learning ; I.2.7
    Subject code 004
    Publishing date 2024-01-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Anti-freezing, recoverable and transparent conductive hydrogels co-reinforced by ethylene glycol as flexible sensors for human motion monitoring.

    Li, Zhaochun / Yin, Fuqiang / He, Weiwei / Hang, Tianyi / Li, Zhihui / Zheng, Jiajia / Li, Xiping / Jiang, Shaohua / Chen, Yiming

    International journal of biological macromolecules

    2023  Volume 230, Page(s) 123117

    Abstract: Wearable flexible sensors based on conductive hydrogels have received extensive attention in the fields of electronic skin and smart monitoring. However, conductive hydrogels contain a large amount of water, which greatly affects their performances in ... ...

    Abstract Wearable flexible sensors based on conductive hydrogels have received extensive attention in the fields of electronic skin and smart monitoring. However, conductive hydrogels contain a large amount of water, which greatly affects their performances in harsh environments. It is therefore necessary to prepare hydrogel sensors that are stable at low temperatures. Herein, metal ions (MgCl
    MeSH term(s) Humans ; Cold Temperature ; Electric Conductivity ; Hydrogels ; Water ; Ethylene Glycols
    Chemical Substances polyvinyl alcohol hydrogel ; Hydrogels ; Water (059QF0KO0R) ; Ethylene Glycols
    Language English
    Publishing date 2023-01-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.123117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Melatonin regulates trophoblast pyroptosis, invasion and migration in preeclampsia by inhibiting HtrA1 transcription through the microRNA-520c-3p/SETD7 axis.

    Liu, Zhaochun / Chen, Bin / Chang, Jing / Feng, Lulu / Zhao, Xia

    American journal of reproductive immunology (New York, N.Y. : 1989)

    2022  Volume 87, Issue 4, Page(s) e13523

    Abstract: Objective: Melatonin has an inhibitory effect on preeclampsia (PE). This study was launched to explore the way that melatonin regulated trophoblast migration, invasion, and pyroptosis in PE and to provide new ideas for the diagnosis and treatment of PE.! ...

    Abstract Objective: Melatonin has an inhibitory effect on preeclampsia (PE). This study was launched to explore the way that melatonin regulated trophoblast migration, invasion, and pyroptosis in PE and to provide new ideas for the diagnosis and treatment of PE.
    Methods: Expression levels of melatonin receptors (MT1 and MT2), microRNA (miR)-520c-3p, SETD7, and HtrA1 in placental tissues and HTR8/SVneo cells were measured by RT-qPCR and Western blot. Scratch, Transwell, and Western blot assays were performed to detect migration, invasion, and pyroptosis of hypoxia/reoxygenation (H/R)-treated HTR8/SVneo cells. Dual-luciferase reporter assay was utilized to verify the targeting relationship between miR-520c-3p and SETD7. ChIP experiment was conducted to detect the enrichment of H3K4me3 and SETD7 in HtrA1 promoter.
    Results: Low expression of MT1, MT2, and miR-520c-3p and high expression of SETD7 and HtrA1 were observed in the placental tissues of PE patients and H/R-treated HTR8/Svneo cells. A high concentration of melatonin promoted migration and invasion and inhibited pyroptosis of PE cell models. Knockdown of miR-520c-3p, overexpression of SETD7, or overexpression of HtrA1 impaired migration and invasion and accelerated pyroptosis of H/R-treated HTR8/SVneo cells, but these outcomes could be reversed by treatment with 1000 μM melatonin. miR-520c-3p targeted SETD7 which promoted histone methylation in the promoter region of HtrA1.
    Conclusion: Melatonin may inhibit HtrA1 transcription through the miR-520c-3p/SETD7 axis to promote trophoblast invasion and migration and reduce trophoblast pyroptosis in PE.
    MeSH term(s) Cell Movement/genetics ; Cell Proliferation ; Female ; High-Temperature Requirement A Serine Peptidase 1/metabolism ; Histone-Lysine N-Methyltransferase/metabolism ; Humans ; Melatonin/pharmacology ; MicroRNAs/genetics ; Placenta/metabolism ; Pre-Eclampsia/genetics ; Pregnancy ; Pyroptosis ; Trophoblasts/metabolism
    Chemical Substances MIRN520 microRNA, human ; MicroRNAs ; Histone-Lysine N-Methyltransferase (EC 2.1.1.43) ; SETD7 protein, human (EC 2.1.1.43) ; High-Temperature Requirement A Serine Peptidase 1 (EC 3.4.21.-) ; HTRA1 protein, human (EC 3.4.21.-) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2022-02-24
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604542-x
    ISSN 1600-0897 ; 0271-7352 ; 8755-8920 ; 1046-7408
    ISSN (online) 1600-0897
    ISSN 0271-7352 ; 8755-8920 ; 1046-7408
    DOI 10.1111/aji.13523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Application Effects of SBAR Communication Mode in ICU Nursing Physical Restraint Shift.

    Ding, Yanzhi / Wang, Guoying / Chen, He / Kang, Jin / Wu, Zhaochun

    Alternative therapies in health and medicine

    2022  Volume 28, Issue 6, Page(s) 112–117

    Abstract: Context: Correct and effective handovers of patients' information during shift changes can ensure patients' safety and can help an incoming shift of nurses to continuously monitor patients' psychological problems and avoid unnecessary physical ... ...

    Abstract Context: Correct and effective handovers of patients' information during shift changes can ensure patients' safety and can help an incoming shift of nurses to continuously monitor patients' psychological problems and avoid unnecessary physical restraints. Development of a standard procedure for handover of patients who have been physically restrained has important clinical significance related to the smooth continuation of nursing work and assurance of the quality of care.
    Objective: The study intended to investigate the clinical effects of the situation-background-assessment-recommendation (SBAR) communication mode on the quality of the information passed during shift changes about patients in intensive care units (ICUs) who had been physically restrained and to compare it to the clinical effects obtained using traditional methods of communication.
    Design: The study was a retrospective analysis of the process used by nurses who were passing patient's information during shift changes when caring for patients who had been physically restrained.
    Setting: The study took place in an ICU at the Second Hospital of Hebei Medical University in Shijiazhuang, Hebei, China.
    Participants: Participants were 21 nurses caring for 239 ICU patients under physical restraint at the Second Hospital.
    Intervention: Of the 239 patients, 118 had been hospitalized between March 1 and March 15, 2018 and were assigned to the control group, and 121 had been hospitalized between June 1 and June 15, 2018 and were assigned to the intervention group. An ICU Physical Restraint Handover Order was established according to the SBAR communication mode. The intervention group used the SBAR communication mode and the control group used the hospital's routine communication mode for the physical restraint of a patient during a nursing shift.
    Outcome measures: The study measured the differences between the groups in the nurses' passing rates based on standards for the use of physical restraints, the quality of handover of information during shift changes about patients under physical restraint, the quality of the documentation written by nurses about the physical restraint, and the nurses' satisfaction with the handover of information during a shift change.
    Results: Among the patient, 112 in the intervention group (92.56%) and 92 in the control group (77.97%) were qualified for physical restraint. A statistically significant difference existed between the two groups in the passing rate for the use of physical restraints (P = .001). The quality score for the handovers during shift changes of patients under physical restraint in the intervention group was 95.46 ± 2.50 and for the control group was 91.08 ± 3.57, with the difference being statistically significant (P = .030). The quality score for the nursing documentation for the intervention group, at 97.21 ± 1.49, was higher than that of the control group, at 90.78 ± 3.42, and the difference was statistically significant (P < .001). The nurses' satisfaction score for the intervention group, at 98.14 ± 1.01 was higher than that of the control group, at 92.57 ± 1.86, and the difference was statistically significant (P = .006).
    Conclusions: The use of the SBAR communication mode to improve the information passed to nurses about patients under physical restraint during a shift change can improve the quality of the physical restraint and nurses' satisfaction and has a better clinical-application effect than the traditional methods used during shift changes.
    MeSH term(s) China ; Communication ; Humans ; Intensive Care Units ; Restraint, Physical ; Retrospective Studies
    Language English
    Publishing date 2022-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Intent-calibrated Self-training for Answer Selection in Open-domain Dialogues

    Deng, Wentao / Pei, Jiahuan / Ren, Zhaochun / Chen, Zhumin / Ren, Pengjie

    2023  

    Abstract: Answer selection in open-domain dialogues aims to select an accurate answer from candidates. Recent success of answer selection models hinges on training with large amounts of labeled data. However, collecting large-scale labeled data is labor-intensive ... ...

    Abstract Answer selection in open-domain dialogues aims to select an accurate answer from candidates. Recent success of answer selection models hinges on training with large amounts of labeled data. However, collecting large-scale labeled data is labor-intensive and time-consuming. In this paper, we introduce the predicted intent labels to calibrate answer labels in a self-training paradigm. Specifically, we propose the intent-calibrated self-training (ICAST) to improve the quality of pseudo answer labels through the intent-calibrated answer selection paradigm, in which we employ pseudo intent labels to help improve pseudo answer labels. We carry out extensive experiments on two benchmark datasets with open-domain dialogues. The experimental results show that ICAST outperforms baselines consistently with 1%, 5% and 10% labeled data. Specifically, it improves 2.06% and 1.00% of F1 score on the two datasets, compared with the strongest baseline with only 5% labeled data.

    Comment: This arXiv version is a pre-MIT Press publication version, this paper has been accepted by TACL. 16 pages, 3 figures, 4 tables
    Keywords Computer Science - Computation and Language
    Subject code 006
    Publishing date 2023-07-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Anti-freezing, recoverable and transparent conductive hydrogels co-reinforced by ethylene glycol as flexible sensors for human motion monitoring

    Li, Zhaochun / Yin, Fuqiang / He, Weiwei / Hang, Tianyi / Li, Zhihui / Zheng, Jiajia / Li, Xiping / Jiang, Shaohua / Chen, Yiming

    International Journal of Biological Macromolecules. 2023 Mar., v. 230 p.123117-

    2023  

    Abstract: Wearable flexible sensors based on conductive hydrogels have received extensive attention in the fields of electronic skin and smart monitoring. However, conductive hydrogels contain a large amount of water, which greatly affects their performances in ... ...

    Abstract Wearable flexible sensors based on conductive hydrogels have received extensive attention in the fields of electronic skin and smart monitoring. However, conductive hydrogels contain a large amount of water, which greatly affects their performances in harsh environments. It is therefore necessary to prepare hydrogel sensors that are stable at low temperatures. Herein, metal ions (MgCl₂) and ethylene glycol (EG) were combined with polyvinyl alcohol (PVA) to obtain a conductive PVA/EG hydrogel with tensile strength and elongation at break of 1.1 MPa and 442.3 %, respectively, which could withstand >6000-fold its own weight. The binary solvent system composed of water and EG contributed to the excellent anti-freezing properties and long-term storage (>1 week), flexibility, and stability of the hydrogel even at −20 °C. The wearable PVA/EG hydrogel as a flexible sensor possessed desirable sensing performances with a competitive GF value of 0.725 and fatigue resistance (50 cycles) when used to monitor various human motions and physiological signals. Overall, this hydrogel sensor shows strong potential for application in the fields of human motion monitoring, written information sensing, and information encryption and transmission.
    Keywords electronic equipment ; ethylene glycol ; humans ; hydrogels ; polyvinyl alcohol ; solvents ; storage time ; tensile strength ; Flexible sensor ; Human motion monitoring ; Information encryption transmission
    Language English
    Dates of publication 2023-03
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.123117
    Database NAL-Catalogue (AGRICOLA)

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