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  1. Article ; Online: The relative age effect and its influence on athletic performance in Chinese junior female' tennis players.

    Aku, Yisheng / Yang, Chengbo

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0298975

    Abstract: The relative age effect (RAE) has been the focus of numerous studies; however, there are still fewer studies in women's sports than in men's sports. In this study, all female players (N = 2,255) who participated in Chinese junior tennis competitions (U12, ...

    Abstract The relative age effect (RAE) has been the focus of numerous studies; however, there are still fewer studies in women's sports than in men's sports. In this study, all female players (N = 2,255) who participated in Chinese junior tennis competitions (U12, U14, U16, and the National Junior Team) from 2014 to 2019 were investigated in terms of competitors' birth dates and year-end rankings. For the purposes of the analysis, the birth dates were also separated into quarters and half years. The study's objectives were to analyze the prevalence of the RAE among young Chinese female tennis players and to further examine how the RAE affects athletic performance. Differences between the observed and expected distributions of birth dates were tested using the chi-square statistic, and subsequent calculations were tested using odds ratios. The RAE was discovered to be present in every group of Chinese junior female tennis players (p < 0.001), with the proportions of those born in the first half of the year being 56.4% (U12), 53.1% (U14), and 57.0% (U16), respectively. The RAE for athletes selected for the National Women's Junior Tennis Team was even more significant, with the percentage of birth dates in the first half of the year at 61.2%. Finally, we observed a tendency for the effect of the RAE on the athletic performance of adolescent female tennis players to diminish with age.
    MeSH term(s) Male ; Adolescent ; Humans ; Female ; Tennis ; Athletic Performance ; Men ; Athletes ; China ; Age Factors
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The relative age effect among Chinese junior men's tennis players and its impact on sports performance.

    Yisheng Aku / Cheng-Bo Yang

    PLoS ONE, Vol 18, Iss 10, p e

    2023  Volume 0292443

    Abstract: The relative age effect (RAE) has been the subject of many studies, but no relevant literature has discussed the phenomenon of RAE in Chinese tennis. Numerous studies have demonstrated that RAE significantly contributes to brain drain and other ... ...

    Abstract The relative age effect (RAE) has been the subject of many studies, but no relevant literature has discussed the phenomenon of RAE in Chinese tennis. Numerous studies have demonstrated that RAE significantly contributes to brain drain and other occurrences that create inequity. This paper analyzes the birth dates and year-end rankings of all male players (N = 2697) who participated in China's junior tennis tournaments (U12, U14, U16) between 2014 and 2019 and who were selected for China's National Junior Team in 2019 and 2020; the paper classifies the birth dates into quarters and semesters. One of the research objectives of this study is to analyze whether RAE exists in Chinese junior men's tennis and whether RAE exerts an effect on athletes' performance. Differences between the observed and expected birthdate distributions were tested using chi-square statistics, and subsequent calculations were tested using odds ratios. The study found that RAE was present in all Chinese junior male tennis sports groups (p<0.001). The percentages of athletes born in the first half of the year were 56.4% (U12), 60.4% (U14), and 60.4% (U16), and the percentages of those born in the first quarter were 34.1% (U12), 36.4% (U14), and 37.1% (U16). Athletes with birth dates closer to the beginning of the year had a higher probability of achieving excellent athletic performance as a result of RAE, whereas those who were born near the end of the year had a more difficult time achieving strong athletic performance.
    Keywords Medicine ; R ; Science ; Q
    Subject code 796
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The relative age effect among Chinese junior men's tennis players and its impact on sports performance.

    Aku, Yisheng / Yang, Cheng-Bo

    PloS one

    2023  Volume 18, Issue 10, Page(s) e0292443

    Abstract: The relative age effect (RAE) has been the subject of many studies, but no relevant literature has discussed the phenomenon of RAE in Chinese tennis. Numerous studies have demonstrated that RAE significantly contributes to brain drain and other ... ...

    Abstract The relative age effect (RAE) has been the subject of many studies, but no relevant literature has discussed the phenomenon of RAE in Chinese tennis. Numerous studies have demonstrated that RAE significantly contributes to brain drain and other occurrences that create inequity. This paper analyzes the birth dates and year-end rankings of all male players (N = 2697) who participated in China's junior tennis tournaments (U12, U14, U16) between 2014 and 2019 and who were selected for China's National Junior Team in 2019 and 2020; the paper classifies the birth dates into quarters and semesters. One of the research objectives of this study is to analyze whether RAE exists in Chinese junior men's tennis and whether RAE exerts an effect on athletes' performance. Differences between the observed and expected birthdate distributions were tested using chi-square statistics, and subsequent calculations were tested using odds ratios. The study found that RAE was present in all Chinese junior male tennis sports groups (p<0.001). The percentages of athletes born in the first half of the year were 56.4% (U12), 60.4% (U14), and 60.4% (U16), and the percentages of those born in the first quarter were 34.1% (U12), 36.4% (U14), and 37.1% (U16). Athletes with birth dates closer to the beginning of the year had a higher probability of achieving excellent athletic performance as a result of RAE, whereas those who were born near the end of the year had a more difficult time achieving strong athletic performance.
    MeSH term(s) Humans ; Male ; Age Factors ; Athletes ; Athletic Performance ; East Asian People ; Men ; Tennis ; Child ; Adolescent
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0292443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: An extended Bayesian semi-mechanistic dose-finding design for phase I oncology trials using pharmacokinetic and pharmacodynamic information.

    Yang, Chao / Li, Yisheng

    Statistics in medicine

    2023  Volume 43, Issue 4, Page(s) 689–705

    Abstract: We propose a model-based, semi-mechanistic dose-finding (SDF) design for phase I oncology trials that incorporates pharmacokinetic/pharmacodynamic (PK/PD) information when modeling the dose-toxicity relationship. This design is motivated by a phase Ib/II ...

    Abstract We propose a model-based, semi-mechanistic dose-finding (SDF) design for phase I oncology trials that incorporates pharmacokinetic/pharmacodynamic (PK/PD) information when modeling the dose-toxicity relationship. This design is motivated by a phase Ib/II clinical trial of anti-CD20/CD3 T cell therapy in non-Hodgkin lymphoma patients; it extends a recently proposed SDF model framework by incorporating measurements of a PD biomarker relevant to the primary dose-limiting toxicity (DLT). We propose joint Bayesian modeling of the PK, PD, and DLT outcomes. Our extensive simulation studies show that on average the proposed design outperforms some common phase I trial designs, including modified toxicity probability interval (mTPI) and Bayesian optimal interval (BOIN) designs, the continual reassessment method (CRM), as well as an SDF design assuming a latent PD biomarker (SDF-woPD), in terms of the percentage of correct selection of maximum tolerated dose (MTD) and average number of patients allocated to MTD, under a variety of dose-toxicity scenarios. When the working PK model and the class of link function between the cumulative PD effect and DLT probability is correctly specified, the proposed design also yields better estimated dose-toxicity curves than CRM and SDF-woPD. Our sensitivity analyses suggest that the design's performance is reasonably robust to prior specification for the parameter in the link function, as well as misspecification of the PK model and class of the link function.
    MeSH term(s) Humans ; Bayes Theorem ; Neoplasms/drug therapy ; Computer Simulation ; Biomarkers ; Maximum Tolerated Dose ; Dose-Response Relationship, Drug ; Research Design
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-12-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.9980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Research on the potential for China to achieve carbon neutrality: A hybrid prediction model integrated with elman neural network and sparrow search algorithm.

    Yang, Meng / Liu, Yisheng

    Journal of environmental management

    2022  Volume 329, Page(s) 117081

    Abstract: China's carbon reduction is of substantial significance in combating global climate change. In the context of the COVID-19 epidemic hit and economic and social development uncertainty, this study intends to discover whether China can attain the strategic ...

    Abstract China's carbon reduction is of substantial significance in combating global climate change. In the context of the COVID-19 epidemic hit and economic and social development uncertainty, this study intends to discover whether China can attain the strategic destination of carbon peaking by 2030 and carbon neutrality by 2060 on schedule. Toward this aim, the grey relation analysis (GRA) is applied to filter the elements influencing carbon emissions to downgrade the dimensionality of indicators. A hybrid prediction is proposed integrated with Elman neural network (ENN) and sparrow search algorithm (SSA) to explore the potential for China to carbon neutrality from 2020 to 2060. The results reveal eight elements including GDP per capita, population, urbanization, total energy consumption and others are highly correlated with carbon emissions. China has a good chance of carbon peaking from 2028 to 2030, with a value of 11568.6-12330.5 Mt, while only one scenario can achieve carbon neutrality in 2060. In the neutral scenario, China should reach a proportion of renewable energy exceeding 80%, the urbanization rate reaching 85% and energy consumption controlling within 6.5 billion tons. A set of countermeasures for carbon abatement are presented to facilitate the implementation of carbon neutrality strategy.
    MeSH term(s) Humans ; Algorithms ; Carbon ; Carbon Dioxide ; China ; COVID-19 ; Economic Development ; Neural Networks, Computer ; Climate Change ; Renewable Energy ; Conservation of Natural Resources
    Chemical Substances Carbon (7440-44-0) ; Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2022-12-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2022.117081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Amplifying dual-visible-light photoswitching in aqueous media

    Wang, Wenhui / Yang, Weixin / Zhang, Zhiwei / Dai, Jinghong / Xu, Yisheng / Zhang, Junji

    Chemical science

    2024  Volume 15, Issue 15, Page(s) 5539–5547

    Abstract: Achieving visible-light photochromism is a long-term goal of chemists keen to exploit the opportunities of molecular photoswitches in multi-disciplinary research studies. Triplet-sensitization offers a flexible approach to building diverse visible-light ... ...

    Abstract Achieving visible-light photochromism is a long-term goal of chemists keen to exploit the opportunities of molecular photoswitches in multi-disciplinary research studies. Triplet-sensitization offers a flexible approach to building diverse visible-light photoswitches using existing photochromic scaffolds, circumventing the need for sophisticated molecular design and synthesis. Unfortunately, distance-dependence and environment-sensitivity of triplet-excited species remain as key challenges that severely impair sensitization efficiency and limit their practical availability. We present herein a nature-inspired nanoconfinement strategy in which a triplet-sensitized visible-light photoswitch/sensitizer system is assembled into nanoconfined micelles (
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d4sc00423j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Robust adaptive three-dimensional trajectory tracking control scheme design for small fixed-wing UAVs.

    Yang, Wenlong / Shi, Zongying / Zhong, Yisheng

    ISA transactions

    2023  Volume 141, Page(s) 377–391

    Abstract: This paper aims to tackle the three-dimensional trajectory tracking problems of small fixed-wing unmanned aerial vehicles subject to nonlinearities, uncertainties and wind disturbances via adaptive techniques. The control objective is to efficiently ... ...

    Abstract This paper aims to tackle the three-dimensional trajectory tracking problems of small fixed-wing unmanned aerial vehicles subject to nonlinearities, uncertainties and wind disturbances via adaptive techniques. The control objective is to efficiently control the thrust and the deflections of control surfaces to ensure the unmanned aerial vehicle arrives at a specified location within a given time frame. However, achieving this goal for small fixed-wing unmanned aerial vehicles can be challenging because the precise dynamic model and several parameters are not accessible, making most existing control strategies unworkable. Motivated by these facts, based on feedback linearization techniques, we derive linear models with equivalent disturbances to describe the translational dynamics without requiring precise aerodynamic force model information. To deal with the dilemmas where the norm bounds of equivalent disturbances depend on control inputs, system states, and unknown disturbances, a novel robust adaptive control strategy is designed for position control. Based on the assumption of two-time separation, the control scheme incorporates two parts, namely, a position controller containing the horizontal-plane and altitude parts and a robust filter-based attitude regulator. Also, to prevent chattering issues, we design a practical and robust adaptive position controller under which the tracking error is ultimately bounded The overall closed-loop stability is theoretically investigated based on the Lyapunov arguments. Hardware-in-loop simulation experiments are performed to testify our developed control scheme.
    Language English
    Publishing date 2023-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2023.06.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Shimmering emerging adulthood: in search of the invariant IDEA model for collectivistic countries.

    Yerofeyeva, Victoria G / Wang, Pai / Yang, Yisheng / Serobyan, Astghik K / Grigoryan, Ani K / Nartova-Bochaver, Sofya K

    Frontiers in psychology

    2024  Volume 15, Page(s) 1349375

    Abstract: Emerging adulthood is the youth trajectory characterized by self-focus, identity exploration, feeling between adolescence and adulthood, instability, and experimentation. This trajectory was first identified in industrialized individualistic countries ... ...

    Abstract Emerging adulthood is the youth trajectory characterized by self-focus, identity exploration, feeling between adolescence and adulthood, instability, and experimentation. This trajectory was first identified in industrialized individualistic countries with gender equality and technological progress. To measure transition to adulthood, the Inventory of the Dimensions of Emerging Adulthood (
    Language English
    Publishing date 2024-04-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2024.1349375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer

    Wang, Lu / Yang, Da / Zhang, Yao / Jiao, Yisheng

    Frontiers in oncology

    2022  Volume 12, Page(s) 932689

    Abstract: Epithelial ovarian cancer (EOC) is one of the most lethal gynecological malignancies in women worldwide. G protein-coupled receptor 12 (GPR12) is a member of G protein-coupled receptors (GPCRs) and plays an important role in the regulation of cell ... ...

    Abstract Epithelial ovarian cancer (EOC) is one of the most lethal gynecological malignancies in women worldwide. G protein-coupled receptor 12 (GPR12) is a member of G protein-coupled receptors (GPCRs) and plays an important role in the regulation of cell proliferation and survival. However, its role in EOC is underappreciated. In this study, we found that GPR12 is highly expressed in the EOC tissues and can be an ideal biomarker to predict the prognosis of patients with EOC. GPR12 knockdown obviously inhibits the proliferation of EOC cells by inducing cellular apoptosis
    Language English
    Publishing date 2022-07-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.932689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Caseinophosphopeptides Overcome Calcium Phytate Inhibition on Zinc Bioavailability by Retaining Zinc from Coprecipitation as Zinc/Calcium Phytate Nanocomplexes.

    Feng, Yinong / Zhu, Suqin / Yang, Yisheng / Li, Shiyang / Zhao, Zifang / Wu, Haohao

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 9, Page(s) 4757–4764

    Abstract: Caseinophosphopeptides have shown great potential to increase zinc bioavailability from phytate-rich diets, but the mechanism of action remains unclear. Here, caseinophosphopeptides from a sodium caseinate hydrolysate dose-dependently retained zinc in ... ...

    Abstract Caseinophosphopeptides have shown great potential to increase zinc bioavailability from phytate-rich diets, but the mechanism of action remains unclear. Here, caseinophosphopeptides from a sodium caseinate hydrolysate dose-dependently retained zinc in solution against calcium phytate coprecipitation under physiologically relevant conditions. The 3 kDa ultrafiltration separation unveiled no added low-molecular-weight chelates of zinc and calcium by caseinophosphopeptides. Tyndall effect, dynamic light scattering measurements, transmission electron microscopy observation, electron diffraction pattern, X-ray diffraction spectrum, and energy-dispersive X-ray analysis demonstrated the caseinophosphopeptides-mediated formation of single-crystal zinc/calcium phytate nanocomplexes (Zn/CaPA-NCs) with a size and ζ-potential of 10-30 nm and -25 mV, respectively. Caseinophosphopeptides-stabilized Zn/CaPA-NCs were found to deliver bioavailable nanoparticulate zinc in mouse jejunal loop
    MeSH term(s) Humans ; Mice ; Animals ; Zinc/analysis ; Biological Availability ; Phytic Acid/analysis ; Caco-2 Cells ; Diet ; Calcium/metabolism
    Chemical Substances Zinc (J41CSQ7QDS) ; Phytic Acid (7IGF0S7R8I) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c07495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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