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  1. Article: First Reported Case of Atypical Meningioma in an Individual with Down Syndrome.

    Vanderschelden, Rachel / Golshani, Kiarash / Evans, Mark G

    Case reports in neurology

    2022  Volume 14, Issue 1, Page(s) 191–196

    Abstract: Individuals with Down syndrome are at decreased risk of developing most types of solid tumors, including central nervous system malignancies. Several mechanisms have been proposed to explain how additional genetic material on chromosome 21 may confer ... ...

    Abstract Individuals with Down syndrome are at decreased risk of developing most types of solid tumors, including central nervous system malignancies. Several mechanisms have been proposed to explain how additional genetic material on chromosome 21 may confer this increased protection. Only two individuals with Down syndrome and meningioma have been described in the medical literature, whose tumors were both World Health Organization (WHO) grade 1. Here, we report the first individual with Down syndrome to our knowledge who developed an atypical meningioma, WHO grade 2. We also provide a hypothesis for how this tumor could have arisen in the setting of trisomy 21.
    Language English
    Publishing date 2022-04-04
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2505302-4
    ISSN 1662-680X
    ISSN 1662-680X
    DOI 10.1159/000523665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reconciling Regulation with Scientific Autonomy in Dual-Use Research.

    Evans, Nicholas G / Selgelid, Michael J / Simpson, Robert Mark

    The Journal of medicine and philosophy

    2022  Volume 47, Issue 1, Page(s) 72–94

    Abstract: In debates over the regulation of communication related to dual-use research, the risks that such communication creates must be weighed against against the value of scientific autonomy. The censorship of such communication seems justifiable in certain ... ...

    Abstract In debates over the regulation of communication related to dual-use research, the risks that such communication creates must be weighed against against the value of scientific autonomy. The censorship of such communication seems justifiable in certain cases, given the potentially catastrophic applications of some dual-use research. This conclusion however, gives rise to another kind of danger: that regulators will use overly simplistic cost-benefit analysis to rationalize excessive regulation of scientific research. In response to this, we show how institutional design principles and normative frameworks from free speech theory can be used to help extend the argument for regulating dangerous dual-use research beyond overly simplistic cost-benefit reasoning, but without reverting to an implausibly absolutist view of scientific autonomy.
    MeSH term(s) Communication ; Dissent and Disputes ; Humans ; Personal Autonomy
    Language English
    Publishing date 2022-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197282-0
    ISSN 1744-5019 ; 0360-5310
    ISSN (online) 1744-5019
    ISSN 0360-5310
    DOI 10.1093/jmp/jhab041
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1265: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Sensor-Based Detection of Predator Influence on Livestock: A Case Study Exploring the Impacts of Wild Dogs (

    Evans, Caitlin A / Trotter, Mark G / Manning, Jaime K

    Animals : an open access journal from MDPI

    2022  Volume 12, Issue 3

    Abstract: In Australia, wild dogs are one of the leading causes of sheep losses. A major problem with managing wild dogs in Australia's rangeland environments is that sheep producers are often unaware of their presence until injuries or deaths are observed. One ... ...

    Abstract In Australia, wild dogs are one of the leading causes of sheep losses. A major problem with managing wild dogs in Australia's rangeland environments is that sheep producers are often unaware of their presence until injuries or deaths are observed. One option for earlier detection of wild dogs is on-animal sensors, such as Global Positioning System (GPS) tracking collars, to detect changes in the behaviour of sheep due to the presence of wild dogs. The current study used spatio-temporal data, derived from GPS tracking collars, deployed on sheep from a single rangeland property to determine if there were differences in the behaviour of sheep when in the presence, or absence, of a wild dog. Results indicated that the presence of a wild dog influenced the daily behaviours of sheep by increasing the daily distance travelled. Differences in sheep diurnal activity were also observed during periods where a wild dog was present or absent on the property. These results highlight the potential for on-animal sensors to be used as a monitoring tool for sheep flocks directly impacted by wild dogs, although further work is needed to determine the applicability of these results to other sheep production regions of Australia.
    Language English
    Publishing date 2022-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12030219
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  4. Article: Case report: The activity of multi-kinase VEGF inhibitor, Pazopanib, in metastatic undifferentiated round cell sarcomas harboring

    Campoverde, Leticia / Camacho, Felipe / Alessandrino, Francesco / Evans, Mark G / Elliot, Andrew / Rosenberg, Andrew / Trent, Jonathan

    Frontiers in oncology

    2023  Volume 13, Page(s) 1215003

    Abstract: Soft tissue sarcomas ... ...

    Abstract Soft tissue sarcomas harboring
    Language English
    Publishing date 2023-09-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1215003
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  5. Article ; Online: Sensor-based detection of a Haemonchus contortus (Barber's pole worm) infection in sheep

    Eloise S. Fogarty / Caitlin A. Evans / Mark G. Trotter / Jaime K. Manning

    Smart Agricultural Technology, Vol 3, Iss , Pp 100112- (2023)

    1480  

    Abstract: Haemonchus contortus, or Barber's Pole worm, is considered one of the most pathogenic parasites of sheep due to the production, profitability and animal welfare implications associated with infections. However, detection of H. contortus infections by ... ...

    Abstract Haemonchus contortus, or Barber's Pole worm, is considered one of the most pathogenic parasites of sheep due to the production, profitability and animal welfare implications associated with infections. However, detection of H. contortus infections by routine observation of sheep flocks is difficult, and producers are usually unaware of a problem until animals are severely infected. The aim of the current study was to explore the potential for accelerometer-based activity monitoring to detect H. contortus infections in sheep.A three-month clinical study was conducted in Central Queensland, Australia, whereby 45, 12-month-old merino wethers were randomly allocated to one of three treatment groups: control (n = 9), low H. contortus infection (n = 18) or high H. contortus infection (n = 18). Infection occurred on Day 0, and accelerometer sensors were attached to a halter and deployed on all animals from Day 21 to Day 70. Animals were sampled weekly (faecal and blood) and treated with an anthelmintic on Day 56. Following the clinical period, five study animals were observed for a total of five hours to compare direct behavioral observations against accelerometer data. This was then used to develop a machine learning (ML) model to classify the accelerometer data into active or inactive behavior, which was further summarized to determine the proportion of time spent active per day. The most valuable features in the selected ML model were movement variation (MV), maximum X-axis value (MaxX), standard deviation of the X-axis (SDX), maximum Y-axis value (MaxY) and standard deviation of the Z-axis (SDZ).Linear mixed-effects models identified a significant difference in all sheep activity pre- and post-anthelmintic drench on Day 56 (P < 0.001). Conversely, there was no significant difference between activity levels of infected animals compared to controls (P = 0.14). To further explore how the activity of sheep changed with clinical presentations of H. contortus infections, weekly faecal egg count (FEC) and blood packed ...
    Keywords Accelerometer ; Nematode ; Parasite ; Precision Livestock Management ; Remote detection ; Sheep ; Agriculture (General) ; S1-972 ; Agricultural industries ; HD9000-9495
    Subject code 630
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Sensor-Based Detection of Predator Influence on Livestock

    Caitlin A. Evans / Mark G. Trotter / Jaime K. Manning

    Animals, Vol 12, Iss 219, p

    A Case Study Exploring the Impacts of Wild Dogs ( Canis familiaris ) on Rangeland Sheep

    2022  Volume 219

    Abstract: In Australia, wild dogs are one of the leading causes of sheep losses. A major problem with managing wild dogs in Australia’s rangeland environments is that sheep producers are often unaware of their presence until injuries or deaths are observed. One ... ...

    Abstract In Australia, wild dogs are one of the leading causes of sheep losses. A major problem with managing wild dogs in Australia’s rangeland environments is that sheep producers are often unaware of their presence until injuries or deaths are observed. One option for earlier detection of wild dogs is on-animal sensors, such as Global Positioning System (GPS) tracking collars, to detect changes in the behaviour of sheep due to the presence of wild dogs. The current study used spatio-temporal data, derived from GPS tracking collars, deployed on sheep from a single rangeland property to determine if there were differences in the behaviour of sheep when in the presence, or absence, of a wild dog. Results indicated that the presence of a wild dog influenced the daily behaviours of sheep by increasing the daily distance travelled. Differences in sheep diurnal activity were also observed during periods where a wild dog was present or absent on the property. These results highlight the potential for on-animal sensors to be used as a monitoring tool for sheep flocks directly impacted by wild dogs, although further work is needed to determine the applicability of these results to other sheep production regions of Australia.
    Keywords behaviour ; on-animal sensors ; predation ; rangelands ; sheep ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Subject code 630
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue.

    Evans, Mark G / Guccione, Jack P / Crymes, Anthony / Li, Xiaodong / Johnson, Cary A / Chandan, Vishal S / Lu, Yuxin

    Case reports in gastrointestinal medicine

    2023  Volume 2023, Page(s) 4073588

    Abstract: Collagenous gastritis has been reported as a rare cause of nausea, diarrhea, weight changes, and early satiety in female patients. Here, we describe two women aged 43 and 71 years who presented with similar symptoms. Gastric biopsies from both ... ...

    Abstract Collagenous gastritis has been reported as a rare cause of nausea, diarrhea, weight changes, and early satiety in female patients. Here, we describe two women aged 43 and 71 years who presented with similar symptoms. Gastric biopsies from both individuals showed thickened, irregular subepithelial collagen bands (>10
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627636-7
    ISSN 2090-6536 ; 2090-6528
    ISSN (online) 2090-6536
    ISSN 2090-6528
    DOI 10.1155/2023/4073588
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  8. Article: Splenic marginal zone B-cell lymphoma associated with ruptured breast implants: case report and review of the literature.

    Evans, Mark G / Mueller, Melissa A / Chen, Frederik / Nichter, Larry S

    Case reports in plastic surgery & hand surgery

    2021  Volume 8, Issue 1, Page(s) 46–49

    Abstract: We describe splenomegaly and bilateral grade 2 Baker breast capsular contracture in a woman who had undergone augmentation mammoplasty. This case represents the first documented instance of splenic marginal zone lymphoma, and is among the rare reports of ...

    Abstract We describe splenomegaly and bilateral grade 2 Baker breast capsular contracture in a woman who had undergone augmentation mammoplasty. This case represents the first documented instance of splenic marginal zone lymphoma, and is among the rare reports of B-cell lymphoma, arising in a patient with breast implants.
    Language English
    Publishing date 2021-04-05
    Publishing country United States
    Document type Case Reports
    ISSN 2332-0885
    ISSN 2332-0885
    DOI 10.1080/23320885.2021.1891903
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  9. Article ; Online: Characterization of ectopic myelinated nerve fibers in the retina of a cynomolgus monkey (Macaca fascicularis).

    Shirai, Norimitsu / Evans, Mark G

    Journal of medical primatology

    2018  Volume 47, Issue 3, Page(s) 198–200

    Abstract: We report histopathology of retinal myelination discovered in a cynomolgus monkey. It consisted of a uniform population of spindle cells arranged in fascicles within the retina at the optic disk. The present case is remarkable in that there is a paucity ... ...

    Abstract We report histopathology of retinal myelination discovered in a cynomolgus monkey. It consisted of a uniform population of spindle cells arranged in fascicles within the retina at the optic disk. The present case is remarkable in that there is a paucity of reports describing myelinated retinal nerve fibers in monkeys.
    MeSH term(s) Animals ; Choristoma/pathology ; Macaca fascicularis ; Male ; Monkey Diseases/pathology ; Nerve Fibers, Myelinated/pathology ; Retina/pathology
    Language English
    Publishing date 2018-02-15
    Publishing country Denmark
    Document type Case Reports
    ZDB-ID 121206-0
    ISSN 1600-0684 ; 0047-2565
    ISSN (online) 1600-0684
    ISSN 0047-2565
    DOI 10.1111/jmp.12335
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 819: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Testicular microlithiasis in a clinically healthy cynomolgus monkey (

    Shirai, Norimitsu / Evans, Mark G

    Journal of toxicologic pathology

    2018  Volume 31, Issue 2, Page(s) 147–150

    Abstract: The present article describes an occurrence of testicular microlithiasis in a cynomolgus monkey from a routine regulatory toxicology study. The monkey was from a negative control group. Microscopically, the lesion was characterized by multiple ... ...

    Abstract The present article describes an occurrence of testicular microlithiasis in a cynomolgus monkey from a routine regulatory toxicology study. The monkey was from a negative control group. Microscopically, the lesion was characterized by multiple extracellular mineralized calculi within seminiferous tubular epithelia of both testes without any tissue reaction or abnormal condition such as cryptorchidism, testicular neoplasm, or hypogonadism. The present case is remarkable in that there is a paucity of reports on spontaneous testicular microlithiasis in nonhuman primates. It is hoped that this case report will help to facilitate the differentiation of spontaneous changes from induced changes in nonhuman primate toxicology studies that are designed to use limited numbers of animals.
    Language English
    Publishing date 2018-02-18
    Publishing country Japan
    Document type Case Reports
    ZDB-ID 2128461-1
    ISSN 1881-915X ; 0914-9198
    ISSN (online) 1881-915X
    ISSN 0914-9198
    DOI 10.1293/tox.2017-0065
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