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  1. Article ; Online: The Burden of Memory: Response to Ortega.

    Rijkers, Ger

    Trends in immunology

    2020  Volume 41, Issue 10, Page(s) 856

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Immunologic Memory ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-28
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2036831-8
    ISSN 1471-4981 ; 1471-4906
    ISSN (online) 1471-4981
    ISSN 1471-4906
    DOI 10.1016/j.it.2020.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: "Get a shot of rhythm and blues": Songs on corona and COVID-19 vaccination.

    Rijkers, Ger T / Braas, Olivier

    Vaccine: X

    2022  Volume 10, Page(s) 100155

    Language English
    Publishing date 2022-03-19
    Publishing country England
    Document type Journal Article
    ISSN 2590-1362
    ISSN (online) 2590-1362
    DOI 10.1016/j.jvacx.2022.100155
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  4. Article ; Online: Tuberculosis, the unsung infectious disease.

    Rijkers, Ger T

    Tuberculosis (Edinburgh, Scotland)

    2019  Volume 115, Page(s) 24–25

    MeSH term(s) Humans ; Music ; Mycobacterium tuberculosis ; Singing ; Terminology as Topic ; Tuberculosis
    Language English
    Publishing date 2019-01-24
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2046804-0
    ISSN 1873-281X ; 1472-9792
    ISSN (online) 1873-281X
    ISSN 1472-9792
    DOI 10.1016/j.tube.2019.01.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Back to the Future: Immune Protection or Enhancement of Future Coronaviruses.

    Bartels, Merit / Sala Solé, Eric / Sauerschnig, Lotte M / Rijkers, Ger T

    Microorganisms

    2024  Volume 12, Issue 3

    Abstract: Before the emergence of SARS-CoV-1, MERS-CoV, and most recently, SARS-CoV-2, four other coronaviruses (the alpha coronaviruses NL63 and 229E and the beta coronaviruses OC43 and HKU1) had already been circulating in the human population. These circulating ...

    Abstract Before the emergence of SARS-CoV-1, MERS-CoV, and most recently, SARS-CoV-2, four other coronaviruses (the alpha coronaviruses NL63 and 229E and the beta coronaviruses OC43 and HKU1) had already been circulating in the human population. These circulating coronaviruses all cause mild respiratory illness during the winter seasons, and most people are already infected in early life. Could antibodies and/or T cells, especially against the beta coronaviruses, have offered some form of protection against (severe) COVID-19 caused by infection with SARS-CoV-2? Related is the question of whether survivors of SARS-CoV-1 or MERS-CoV would be relatively protected against SARS-CoV-2. More importantly, would humoral and cellular immunological memory generated during the SARS-CoV-2 pandemic, either by infection or vaccination, offer protection against future coronaviruses? Or rather than protection, could antibody-dependent enhancement have taken place, a mechanism by which circulating corona antibodies enhance the severity of COVID-19? Another related phenomenon, the original antigenic sin, would also predict that the effectiveness of the immune response to future coronaviruses would be impaired because of the reactivation of memory against irrelevant epitopes. The currently available evidence indicates that latter scenarios are highly unlikely and that especially cytotoxic memory T cells directed against conserved epitopes of human coronaviruses could at least offer partial protection against future coronaviruses.
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12030617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cutting the Stone: Health Defined in the Era of Value-based Care.

    Rijkers, Ger

    Cureus

    2017  Volume 9, Issue 2, Page(s) e1023

    Abstract: The immune system contributes to the maintenance of health by preventing and limiting the clinical consequences of infections by pathogenic microorganisms. During the evolution of Homo sapiens, those with the fittest immune system survived. The immune ... ...

    Abstract The immune system contributes to the maintenance of health by preventing and limiting the clinical consequences of infections by pathogenic microorganisms. During the evolution of Homo sapiens, those with the fittest immune system survived. The immune system of Homo sapiens was further improved and adapted by admixture with Neanderthal genes. Nowadays, the human immune system provides adequate protection against the majority of infections. For some 20 infectious diseases, the immune system needs to be improved by vaccination. Vaccination is the number one value-based healthcare intervention and has resulted in global eradication of smallpox. Eradication of poliomyelitis and measles is within reach. A continuous effort will be required for recently emerged pathogens, such as Ebola and HIV, as well as the most difficult - malaria and tuberculosis.
    Language English
    Publishing date 2017-02-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The function of the immune system according to The Other Side of Bob Dylan.

    Rijkers, Ger T

    European journal of immunology

    2017  Volume 47, Issue 7, Page(s) 1094–1095

    Language English
    Publishing date 2017-07
    Publishing country Germany
    Document type News
    ZDB-ID 120108-6
    ISSN 1521-4141 ; 0014-2980
    ISSN (online) 1521-4141
    ISSN 0014-2980
    DOI 10.1002/eji.201770075
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  8. Article: The Impact of SARS-CoV-2 Immune Status and Societal Restrictions in Controlling COVID-19 across the World.

    Stroo, Jasmijn / Lepolder, Michaëla / Murk, Jean-Luc / Rijkers, Ger T

    Vaccines

    2023  Volume 11, Issue 9

    Abstract: To control the COVID-19 pandemic, many countries implemented vaccination and imposed societal restrictions both at the national level and for international travel. As a check of corona status, COVID passes have been issued. A COVID pass could be obtained ...

    Abstract To control the COVID-19 pandemic, many countries implemented vaccination and imposed societal restrictions both at the national level and for international travel. As a check of corona status, COVID passes have been issued. A COVID pass could be obtained when either fully vaccinated against COVID-19, or after recovering from a documented COVID-19 episode, or after a recent (24-48 h) negative SARS-CoV-2 antigen test. A global analysis of SARS-CoV-2 immune status determined by past infection and/or vaccination, vaccination rates, as well as societal restrictions in controlling the COVID-19 pandemic is presented. The data show that across the world, vaccination was more effective in reducing SARS-CoV-2 infections with the delta variant than the omicron variant. Strict societal restrictions could control spread of the virus, but relief of the restrictions was associated with an increase in omicron infections. No significant difference in SARS-CoV-2 infections were found when comparing countries or territories which did or did not implement a COVID pass.
    Language English
    Publishing date 2023-08-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11091407
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  9. Article: Fixing a Hole: Preventing Pneumococcal Pneumonia by Vaccination.

    Rijkers, Ger T

    Frontiers in immunology

    2016  Volume 7, Page(s) 349

    Language English
    Publishing date 2016
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2016.00349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Impact of SARS-CoV-2 Immune Status and Societal Restrictions in Controlling COVID-19 across the World

    Jasmijn Stroo / Michaëla Lepolder / Jean-Luc Murk / Ger T. Rijkers

    Vaccines, Vol 11, Iss 1407, p

    2023  Volume 1407

    Abstract: To control the COVID-19 pandemic, many countries implemented vaccination and imposed societal restrictions both at the national level and for international travel. As a check of corona status, COVID passes have been issued. A COVID pass could be obtained ...

    Abstract To control the COVID-19 pandemic, many countries implemented vaccination and imposed societal restrictions both at the national level and for international travel. As a check of corona status, COVID passes have been issued. A COVID pass could be obtained when either fully vaccinated against COVID-19, or after recovering from a documented COVID-19 episode, or after a recent (24–48 h) negative SARS-CoV-2 antigen test. A global analysis of SARS-CoV-2 immune status determined by past infection and/or vaccination, vaccination rates, as well as societal restrictions in controlling the COVID-19 pandemic is presented. The data show that across the world, vaccination was more effective in reducing SARS-CoV-2 infections with the delta variant than the omicron variant. Strict societal restrictions could control spread of the virus, but relief of the restrictions was associated with an increase in omicron infections. No significant difference in SARS-CoV-2 infections were found when comparing countries or territories which did or did not implement a COVID pass.
    Keywords COVID pass ; SARS-CoV-2 antigen test ; SARS-CoV-2 antibodies ; societal restrictions ; Medicine ; R
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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