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  1. Article: Unusual immunohistochemical "null" pattern of four mismatch repair proteins in gastric cancer: A case report.

    Yue, Meng / Liu, Jun-Ying / Liu, Yue-Ping

    World journal of clinical cases

    2021  Volume 9, Issue 21, Page(s) 6102–6109

    Abstract: Background: Immunohistochemical (IHC) staining for mismatch repair (MMR) proteins is useful for gastric cancer treatment and prognosis. Different IHC staining patterns reflect the complex biological phenomena underlying MMR deficiency. We herein report ... ...

    Abstract Background: Immunohistochemical (IHC) staining for mismatch repair (MMR) proteins is useful for gastric cancer treatment and prognosis. Different IHC staining patterns reflect the complex biological phenomena underlying MMR deficiency. We herein report a rare IHC staining pattern of four MMR-related proteins in gastric cancer.
    Case summary: A "null" IHC staining pattern of four MMR-related proteins, including MLH1, PMS2, MSH2, and MSH6, in a 67-year-old male patient with gastric cancer pT3N3aM0 revealed promoter hypermethylation of
    Conclusion: Abnormal MMR protein expression, helpful for individualized follow-up care, helped identify a sporadic case lacking familial clinical management implications.
    Language English
    Publishing date 2021-07-21
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v9.i21.6102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Tsʻan ping ti fa sheng liu hsing yü yü fang

    Wang, Yü-hsing / Liu, Ching-ho / Tsʻui, Yüan-jen

    1991  

    Title translation Silkworm disease and prevention.
    Title variant Can bing da fa sheng liu xing yu yu fang
    Author's details Wang Yü-hsing, Liu Ching-ho, Tsʻui Yüan-jen pien chu
    Keywords Silkworms/Diseases.
    Language Chinese
    Size 2, 81 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Shan-tung kʻo hsüeh chi shu chʻu pan she ; Shan-tung sheng hsin hua shu tien fa hsing
    Publishing place Chi-nan shih
    Document type Book
    ISBN 7533108647 ; 9787533108649
    Database NAL-Catalogue (AGRICOLA)

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  3. Book: Shou jou chu yang chih yü fang ping

    Ma, Jen-liu / Wang, Jui-chʻi

    1993  

    Title translation Lean meat hog raising and their disease control.
    Title variant Sourouzhu yangzhiyufangbing
    Author's details Ma Jen-liu, Wang Jui-chʻi pien chu ; Ma Yü-tʻang shen chiao
    Keywords Swine ; Swine/Diseases
    Language Chinese
    Size 1, 10, 419 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Shan-hsi kʻo hsüeh chi shu chʻu pan she ; Shan-hsi sheng hsin hua shu tien fa hsing
    Publishing place Tʻai-yüan
    Document type Book
    ISBN 7537706409 ; 9787537706407
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Erythematöse Gesichtsschwellung mit schwärzlicher Schorfbildung.

    Jiang, Yan-Yun / Liu, Wen-Jing / Zeng, Yue-Ping

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2021  Volume 19, Issue 7, Page(s) 1084–1087

    Language English
    Publishing date 2021-05-24
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14440_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6148: Show issues Location:
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  5. Article ; Online: Blackish necrotic eschar with swelling erythema on the face.

    Jiang, Yan-Yun / Liu, Wen-Jing / Zeng, Yue-Ping

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2021  Volume 19, Issue 7, Page(s) 1084–1087

    MeSH term(s) Edema ; Erythema/diagnosis ; Face ; Humans
    Language English
    Publishing date 2021-04-11
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14440
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6148: Show issues Location:
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  6. Book: Yü ping t'iao cha shou ts'e

    Chen, Chi-liu

    1981  

    Title translation A handbook of fish diseases survey.
    Institution Chung-kuo k'o hsüeh yüan. / Yü ping hsüeh yen chiu shih
    Author's details Chung-kuo k'o hsüeh yüan shui sheng sheng wu yen chiu so yü ping hsüeh yen chiu shih pien chu, [Chü pien Chen Chi Liu]. --
    Keywords Fishes/Diseases ; Fishes/Diseases/Identification/Handbooks, manuals, etc.
    Language Chinese
    Size 3, 278 p., [1] p. of col. plates :, ill. ;, 19 cm.
    Edition Ti erh pan. --
    Publisher Shang-hai k'o hsüeh chi shu ch'u pan she
    Publishing place Shang-hai
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Clinical observation of pediatric-type follicular lymphomas in adult: Two case reports.

    Liu, Yao / Xing, Hui / Liu, Yue-Ping

    World journal of clinical cases

    2021  Volume 9, Issue 31, Page(s) 9542–9548

    Abstract: Background: Pediatric-type follicular lymphoma (PTFL) is a unique pathological type in the 4: Case summary: Two cases of PTFL were reported and their clinicopathological features, differential diagnosis, therapy and prognosis were discussed. PTFL ... ...

    Abstract Background: Pediatric-type follicular lymphoma (PTFL) is a unique pathological type in the 4
    Case summary: Two cases of PTFL were reported and their clinicopathological features, differential diagnosis, therapy and prognosis were discussed. PTFL showed gray-brown tough texture in general performance. The histological manifestations of PTFL were similar to that of adult-follicular lymphoma (FL). Under low power microscope, the structure of lymph nodes was destroyed in different degree, the follicles were closely arranged, expanded and irregular, and the mantle zone became thin or disappeared. In addition, the "starry sky phenomenon" could be seen. At high magnification, the follicles were mainly composed of single medium-sized central cells, and some of them mainly consisted of centroblastic cells to characterize scattered chromatin and inconspicuous nucleoli. Immunohistochemical showed the tumor cells expressed CD20, PAX5, CD79a and CD10, BCL6, FOXP-1, which were limited in germinal center; Ki-67 was highly expressed in germinal center. CD21 and CD23 showed nodular and expanded follicular dendritic cells. Immunoglobulin gene rearrangement was positive for IGH and IGK. The two patients underwent surgical resection with no complications. After discharge, the two patients with a close review for 18 mo and 5 mo respectively and showed no evidence of recurrence.
    Conclusion: PTFL in adult is generally supposed to be extremely rare. PTFL displayed characteristic morphological, immunophenotypic, and molecular biological changes which are a kind of neoplasm with satisfactory prognosis after surgical excision.
    Language English
    Publishing date 2021-11-30
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v9.i31.9542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Long-read assembled metagenomic approaches improve our understanding on metabolic potentials of microbial community in mangrove sediments.

    Zhang, Zhi-Feng / Liu, Li-Rui / Pan, Yue-Ping / Pan, Jie / Li, Meng

    Microbiome

    2023  Volume 11, Issue 1, Page(s) 188

    Abstract: Background: Mangrove wetlands are coastal ecosystems with important ecological features and provide habitats for diverse microorganisms with key roles in nutrient and biogeochemical cycling. However, the overall metabolic potentials and ecological roles ...

    Abstract Background: Mangrove wetlands are coastal ecosystems with important ecological features and provide habitats for diverse microorganisms with key roles in nutrient and biogeochemical cycling. However, the overall metabolic potentials and ecological roles of microbial community in mangrove sediment are remained unanswered. In current study, the microbial and metabolic profiles of prokaryotic and fungal communities in mangrove sediments were investigated using metagenomic analysis based on PacBio single-molecule real time (SMRT) and Illumina sequencing techniques.
    Results: Comparing to Illumina short reads, the incorporation of PacBio long reads significantly contributed to more contiguous assemblies, yielded more than doubled high-quality metagenome-assembled genomes (MAGs), and improved the novelty of the MAGs. Further metabolic reconstruction for recovered MAGs showed that prokaryotes potentially played an essential role in carbon cycling in mangrove sediment, displaying versatile metabolic potential for degrading organic carbons, fermentation, autotrophy, and carbon fixation. Mangrove fungi also functioned as a player in carbon cycling, potentially involved in the degradation of various carbohydrate and peptide substrates. Notably, a new candidate bacterial phylum named as Candidatus Cosmopoliota with a ubiquitous distribution is proposed. Genomic analysis revealed that this new phylum is capable of utilizing various types of organic substrates, anaerobic fermentation, and carbon fixation with the Wood-Ljungdahl (WL) pathway and the reverse tricarboxylic acid (rTCA) cycle.
    Conclusions: The study not only highlights the advantages of HiSeq-PacBio Hybrid assembly for a more complete profiling of environmental microbiomes but also expands our understanding of the microbial diversity and potential roles of distinct microbial groups in biogeochemical cycling in mangrove sediment. Video Abstract.
    MeSH term(s) Metagenome/genetics ; Microbiota/genetics ; Metagenomics ; Fermentation ; Carbon
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Video-Audio Media ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2697425-3
    ISSN 2049-2618 ; 2049-2618
    ISSN (online) 2049-2618
    ISSN 2049-2618
    DOI 10.1186/s40168-023-01630-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [AI-assisted Prediction of Lymph Node Metastasis of Breast Cancer: Current and Prospective Research].

    Ding, Yan / Han, Meng-Xue / Liu, Yue-Ping

    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

    2021  Volume 52, Issue 2, Page(s) 162–165

    Abstract: One of the most important application of artificial intelligence (AI) in pathology is prediction, using morphological features, of patient prognosis and response to specific treatments. As one of the most common kinds of malignancies in the world and the ...

    Abstract One of the most important application of artificial intelligence (AI) in pathology is prediction, using morphological features, of patient prognosis and response to specific treatments. As one of the most common kinds of malignancies in the world and the crucial important cause of death due to malignant tumor among women, breast cancer has become the center of attention in clinical services. Axillary lymph node metastasis is an important prognostic factor in breast cancer. The accuracy of the assessment of axillary lymph node metastasis bears heavily on clinical diagnosis and treatment. At present, based on the principle of non-invasive procedures, many studies have been done to develop models that can be used to predict sentinel lymph node metastasis of breast cancer. However, different clinical and pathological parameters are used in these predictive models. How to analyze the clinical and pathological data of breast cancer patients in a more comprehensive way and how to establish a prediction model with better precision have become the future direction of development. In this paper, we describe the research progress of AI in pathology and the current status of its use in breast cancer research. We have conducted in-depth reflection and looked into the future of ways to predict effectively breast cancer lymph node metastasis and to establish more accurate and effective deep-learning algorithm based on AI assistance so as to continuously improve the diagnosis and treatment of breast cancer.
    MeSH term(s) Artificial Intelligence ; Breast Neoplasms/surgery ; Female ; Humans ; Lymph Nodes ; Lymphatic Metastasis ; Prospective Studies ; Sentinel Lymph Node ; Sentinel Lymph Node Biopsy
    Language Chinese
    Publishing date 2021-05-06
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2106840-9
    ISSN 1672-173X
    ISSN 1672-173X
    DOI 10.12182/20210360102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes.

    Li, Jing / Tan, Yu-Fen / Zhou, Si-Qian / Liu, Shao / Wang, Wen-Xuan / Jiang, Yue-Ping / Long, Hong-Ping / Liu, Ji-Kai

    Phytochemistry

    2023  Volume 210, Page(s) 113652

    Abstract: Three undescribed methylsuccinic acid derivatives, xylaril acids A-C, and two undescribed enoic acid derivatives, xylaril acids D-E, were isolated from the fungus Xylaria longipes. The structures of the undescribed compounds were deduced by spectroscopic ...

    Abstract Three undescribed methylsuccinic acid derivatives, xylaril acids A-C, and two undescribed enoic acid derivatives, xylaril acids D-E, were isolated from the fungus Xylaria longipes. The structures of the undescribed compounds were deduced by spectroscopic means, including HRESIMS and 1D/2D NMR spectroscopy, as well as ECD calculations. The absolute configuration of xylaril acids A was further determined by single-crystal X-ray diffraction experiments. All the isolated compounds displayed neuroprotective activities against oxygen-glucose deprivation/reperfusion injury in PC12 cells by enhancing cell viability and inhibiting cell apoptosis.
    MeSH term(s) Rats ; Animals ; Xylariales/chemistry ; Ascomycota ; Magnetic Resonance Spectroscopy ; Molecular Structure
    Chemical Substances methylsuccinic acid (H1547KG7UZ)
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 208884-8
    ISSN 1873-3700 ; 0031-9422
    ISSN (online) 1873-3700
    ISSN 0031-9422
    DOI 10.1016/j.phytochem.2023.113652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Z 1586: Show issues
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