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  1. Article ; Online: Urinary microRNA in Diabetic Kidney Disease: A Literature Review.

    Lee, Chin-Chan / Chen, Chia-Chun / Hsu, Cheng-Kai / Chen, Yih-Ting / Chen, Chun-Yu / Yang, Kai-Jie / Hung, Ming-Jui / Wu, I-Wen

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 2

    Abstract: Diabetic kidney disease is the most common primary disease of end-stage kidney disease globally; however, a sensitive and accurate biomarker to predict this disease remains awaited. microRNAs are endogenous single-stranded noncoding RNAs that have ... ...

    Abstract Diabetic kidney disease is the most common primary disease of end-stage kidney disease globally; however, a sensitive and accurate biomarker to predict this disease remains awaited. microRNAs are endogenous single-stranded noncoding RNAs that have intervened in different post-transcriptional regulations of various cellular biological functions. Previous literatures have reported its potential role in the pathophysiology of diabetic kidney disease, including regulation of Transforming Growth Factor-β1-mediated fibrosis, extracellular matrix and cell adhesion proteins, cellular hypertrophy, growth factor, cytokine production, and redox system activation. Urinary microRNAs have emerged as a novel, non-invasive liquid biopsy for disease diagnosis. In this review, we describe the available experimental and clinical evidence of urinary microRNA in the context of diabetic kidney disease and discuss the future application of microRNA in routine practice.
    MeSH term(s) Humans ; Diabetic Nephropathies/metabolism ; MicroRNAs/genetics ; Kidney/pathology ; Gene Expression Regulation ; Gene Expression ; Diabetes Mellitus/pathology
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59020354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Long-term impacts of endocrine-disrupting chemicals exposure on kidney function: A community-based cohort study.

    Chen, Chun-Yu / Lee, Chin-Chan / Hsu, Heng-Jung / Wu, I-Wen / Chen, Yung-Chang / Pan, Heng-Chih / Chen, Yih-Ting / Hsu, Cheng-Kai / Sun, Chiao-Yin

    Environmental toxicology and pharmacology

    2024  Volume 106, Page(s) 104379

    Abstract: This study explores the extended renal effects of endocrine-disrupting chemicals (EDCs) exposure, a linkage already established with adverse health outcomes, notably chronic kidney disease. To delve deeper, the Chang Gung Community Research Center ... ...

    Abstract This study explores the extended renal effects of endocrine-disrupting chemicals (EDCs) exposure, a linkage already established with adverse health outcomes, notably chronic kidney disease. To delve deeper, the Chang Gung Community Research Center conducted a longitudinal study with 887 participants. Among them, 120 individuals were scrutinized based on EDC scores, analyzing 17 urinary EDCs and renal function. Findings revealed elevated mono-(2-ethylhexyl) phthalate (MEHP) and bisphenol A levels in higher EDC exposure cases. MEHP notably correlated with increased urinary albumin-to-creatinine ratio (UACR), predicting a > 15% decline in estimated glomerular filtration rate. Higher MEHP levels also hinted at declining renal function. UACR escalation linked significantly with specific EDCs: MEHP, methylparaben, nonylphenol, and 4-tert-octylphenol. This research underscores enduring renal hazards tied to environmental EDC exposure, particularly MEHP, emphasizing the urgent call for robust preventive public health strategies.
    MeSH term(s) Humans ; Cohort Studies ; Longitudinal Studies ; Diethylhexyl Phthalate/analogs & derivatives ; Endocrine Disruptors/toxicity ; Kidney
    Chemical Substances mono-(2-ethylhexyl)phthalate (FU2EWB60RT) ; Diethylhexyl Phthalate (C42K0PH13C) ; Endocrine Disruptors
    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1318302-3
    ISSN 1872-7077 ; 1382-6689
    ISSN (online) 1872-7077
    ISSN 1382-6689
    DOI 10.1016/j.etap.2024.104379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Incidence and mortality of pulmonary embolism in COVID-19: a systematic review and meta-analysis.

    Liao, Shu-Chen / Shao, Shih-Chieh / Chen, Yih-Ting / Chen, Yung-Chang / Hung, Ming-Jui

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 464

    MeSH term(s) COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Incidence ; Pandemics ; Pneumonia, Viral/epidemiology ; Pulmonary Embolism/epidemiology ; Pulmonary Embolism/mortality
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country England
    Document type Letter ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03175-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection: a systematic review and meta-analysis.

    Chen, Yih-Ting / Shao, Shih-Chieh / Lai, Edward Chia-Cheng / Hung, Ming-Jui / Chen, Yung-Chang

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 439

    MeSH term(s) Acute Kidney Injury/mortality ; Acute Kidney Injury/virology ; COVID-19 ; Coronavirus Infections/complications ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Severe Acute Respiratory Syndrome/complications
    Keywords covid19
    Language English
    Publishing date 2020-07-16
    Publishing country England
    Document type Letter ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03134-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Performance of urinary C-C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis.

    Chen, Yih-Ting / Pan, Heng-Chih / Hsu, Cheng-Kai / Sun, Chiao-Yin / Chen, Chun-Yu / Chen, Yi-Hung / Hsu, Heng-Jung / Wu, I-Wen / Wu, Vin-Cent / Hoste, Eric

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 318

    Abstract: Background: Urinary C-C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its efficacy has been found to vary between different trials. The goal of this research was to ... ...

    Abstract Background: Urinary C-C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its efficacy has been found to vary between different trials. The goal of this research was to assess the predictive performance of urinary CCL14 as a marker for persistent AKI.
    Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched the PubMed, Embase, and Cochrane databases up to April 2023 for studies of adults (> 18 years) that reported the diagnostic performance of urinary CCL14. The sensitivity, specificity, number of events, true positive, and false positive results were extracted and evaluated. Hierarchical summary receiver operating characteristic curves (HSROCs) were used to summarize the pooled test performance, and the Grading of Recommendations, Assessment, Development and Evaluations criteria were used to appraise the quality of evidence.
    Results: We included six studies with 952 patients in this meta-analysis. The occurrence of persistent AKI among these patients was 39.6% (377/952). The pooled sensitivity and specificity results of urinary CCL14 in predicting persistent AKI were 0.81 (95% CI 0.72-0.87) and 0.71 (95% CI 0.53-0.84), respectively. The pooled positive likelihood ratio (LR) was 2.75 (95% CI 1.63-4.66), and the negative LR was 0.27 (95% CI 0.18-0.41). The HSROC with pooled diagnostic accuracy was 0.84.
    Conclusion: Our results suggest that urinary CCL14 can be used as an effective marker for predicting persistent AKI.
    MeSH term(s) Adult ; Humans ; Acute Kidney Injury/diagnosis ; Chemokines ; Databases, Factual ; Ligands ; ROC Curve
    Chemical Substances Chemokines ; Ligands ; CCL14 protein, human
    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04610-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effects of Low Protein Diet on Modulating Gut Microbiota in Patients with Chronic Kidney Disease: A Systematic Review and Meta-analysis of International Studies.

    Hsu, Cheng-Kai / Su, Shih-Chi / Chang, Lun-Ching / Shao, Shih-Chieh / Yang, Kai-Jie / Chen, Chun-Yu / Chen, Yih-Ting / Wu, I-Wen

    International journal of medical sciences

    2021  Volume 18, Issue 16, Page(s) 3839–3850

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Diet, Protein-Restricted ; Dysbiosis/epidemiology ; Dysbiosis/etiology ; Gastrointestinal Microbiome/physiology ; Humans ; Internationality ; Renal Insufficiency, Chronic/diet therapy ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/microbiology
    Language English
    Publishing date 2021-10-25
    Publishing country Australia
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2151424-0
    ISSN 1449-1907 ; 1449-1907
    ISSN (online) 1449-1907
    ISSN 1449-1907
    DOI 10.7150/ijms.66451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Incidence and mortality of pulmonary embolism in COVID-19

    Shu-Chen Liao / Shih-Chieh Shao / Yih-Ting Chen / Yung-Chang Chen / Ming-Jui Hung

    Critical Care, Vol 24, Iss 1, Pp 1-

    a systematic review and meta-analysis

    2020  Volume 5

    Keywords Pulmonary embolism ; COVID-19 ; Systematic review ; Meta-analysis ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection

    Yih-Ting Chen / Shih-Chieh Shao / Edward Chia-Cheng Lai / Ming-Jui Hung / Yung-Chang Chen

    Critical Care, Vol 24, Iss 1, Pp 1-

    a systematic review and meta-analysis

    2020  Volume 4

    Keywords Acute kidney injury ; Mortality ; COVID-19 ; MERS ; SARS ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Incidence of acute kidney injury in COVID-19 infection

    Yih-Ting Chen / Shih-Chieh Shao / Cheng-Kai Hsu / I-Wen Wu / Ming-Jui Hung / Yung-Chang Chen

    Critical Care, Vol 24, Iss 1, Pp 1-

    a systematic review and meta-analysis

    2020  Volume 4

    Keywords Acute kidney injury ; COVID-19 ; Incidence ; Meta-analysis ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Intraoperative open chest epicardial high-density mapping and ablation for refractory ventricular tachycardia at time of magnetically levitated left ventricular assist device implantation.

    Ho, Li-Ting / Lin, Lian-Yu / Chen, Yih-Sharng / Wang, Chih-Hsien

    JTCVS techniques

    2023  Volume 18, Page(s) 74–77

    Language English
    Publishing date 2023-01-21
    Publishing country United States
    Document type Case Reports
    ISSN 2666-2507
    ISSN (online) 2666-2507
    DOI 10.1016/j.xjtc.2023.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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