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  1. Article ; Online: Implementation of a group coaching initiative for paediatric trainees approaching career transitions.

    Davies, Sarah / Round, Jonathan / Ravindran, Saranya / Bailey, Sheena / Skidmore, Angela / Pattani, Hina / Radia, Trisha

    Archives of disease in childhood. Education and practice edition

    2024  

    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2148818-6
    ISSN 1743-0593 ; 1743-0585
    ISSN (online) 1743-0593
    ISSN 1743-0585
    DOI 10.1136/archdischild-2023-325389
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  2. Article ; Online: When child mental health meets acute paediatrics: A virtual training programme.

    Davies, Sarah / Radia, Trisha / Bedford, Stacey / McDougall, Marilyn

    Medical education

    2022  Volume 56, Issue 11, Page(s) 1132–1133

    MeSH term(s) Child ; Education, Medical, Graduate ; Humans ; Mental Health ; Pediatrics
    Language English
    Publishing date 2022-08-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.14906
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  3. Article ; Online: A case report of pyogenic sacroiliitis in a 9-month-old child.

    Thomas, Sarah / Haque, Saira / Radia, Trisha

    Archive of clinical cases

    2022  Volume 9, Issue 3, Page(s) 108–111

    Abstract: A very rare condition, pyogenic sacroiliitis is responsible for 1-2% of all osteoarticular infections in children. Diagnosis is often delayed in the pediatric population due to non-specific signs and symptoms during presentation, difficulty in assessing ... ...

    Abstract A very rare condition, pyogenic sacroiliitis is responsible for 1-2% of all osteoarticular infections in children. Diagnosis is often delayed in the pediatric population due to non-specific signs and symptoms during presentation, difficulty in assessing the joint, more common differential diagnosis and low yield diagnostic findings in conventional radiography. A delayed diagnosis of this condition can lead to permanent joint damage. A 9-month-old presented to the emergency department with a history of fever, being unsettled and clingy along with refusal to weight bear over the past few days. On initial assessment, she was found to be tachycardic and afebrile with abnormal posture of her left leg held in external rotation at the hip joint. On examination, she refused to weight bear, presented with alternating tenderness of her left and right hip joints and spinal tenderness at the L5 position. Investigations done showed slightly raised inflammatory counts, normal hip and pelvic radiographs, normal hip ultrasound and blood culture growing staphylococcus aureus and Magnetic Resonance Imaging spine showing right sacroiliitis leading the diagnosis of pyogenic sacroiliitis. This case report highlights the importance of examination of the back and the importance of avoiding fixation error by history. Although rare, clinicians should consider the diagnosis of sacroiliitis in children who present with fever, being unsettled with decreased and painful movements around the pelvic region.
    Language English
    Publishing date 2022-09-26
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2788093-X
    ISSN 2360-6975 ; 2360-6975
    ISSN (online) 2360-6975
    ISSN 2360-6975
    DOI 10.22551/2022.36.0903.10213
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  4. Article ; Online: Racial microaggressions within respiratory and critical care medicine.

    Babla, Kunal / Lau, Sinny / Akindolie, Omowunmi / Radia, Trisha / Modi, Neena / Kingdon, Camilla / Bush, Andy / Gupta, Atul

    The Lancet. Respiratory medicine

    2021  Volume 9, Issue 3, Page(s) e27–e28

    MeSH term(s) Aggression ; Critical Care ; Health Personnel/psychology ; Humans ; Pulmonary Medicine ; Racism
    Language English
    Publishing date 2021-03-02
    Publishing country England
    Document type Letter
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00001-1
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  5. Article ; Online: Paediatric sepsis, the under-recognised killer: quality improvement initiative of outreach teaching in paediatric sepsis.

    Stewart, Claire Elizabeth / Radia, Trisha / Ghafoor, Kazim

    Archives of disease in childhood. Education and practice edition

    2017  Volume 102, Issue 5, Page(s) 278–280

    Abstract: Sepsis is the leading cause of child's death, yet it is well known that the rapid initiation of simple, timely interventions reduces morbidity and mortality. This paper shares our findings on the barriers doctors in training have identified to delivering ...

    Abstract Sepsis is the leading cause of child's death, yet it is well known that the rapid initiation of simple, timely interventions reduces morbidity and mortality. This paper shares our findings on the barriers doctors in training have identified to delivering such care. We also share the results of a pilot paediatric intensive care unit outreach teaching programme designed to directly address these highlighted concerns.
    Language English
    Publishing date 2017-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2148818-6
    ISSN 1743-0593 ; 1743-0585
    ISSN (online) 1743-0593
    ISSN 1743-0585
    DOI 10.1136/archdischild-2016-312203
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  6. Article ; Online: COVID-19 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review of critically unwell children and the association with underlying comorbidities.

    Williams, Nia / Radia, Trisha / Harman, Katharine / Agrawal, Pankaj / Cook, James / Gupta, Atul

    European journal of pediatrics

    2020  Volume 180, Issue 3, Page(s) 689–697

    Abstract: Data show that children are less severely affected with SARS-Covid-19 than adults; however, there have been a small proportion of children who have been critically unwell. In this systematic review, we aimed to identify and describe which underlying ... ...

    Abstract Data show that children are less severely affected with SARS-Covid-19 than adults; however, there have been a small proportion of children who have been critically unwell. In this systematic review, we aimed to identify and describe which underlying comorbidities may be associated with severe SARS-CoV-2 disease and death. The study protocol was in keeping with Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. A total of 1726 articles were identified of which 28 studies fulfilled the inclusion criteria. The 28 studies included 5686 participants with confirmed SARS-CoV-2 infection ranging from mild to severe disease. We focused on the 108 patients who suffered from severe/critical illness requiring ventilation, which included 17 deaths. Of the 108 children who were ventilated, the medical history was available for 48 patients. Thirty-six of the 48 patients (75%) had documented comorbidities of which 11/48 (23%) had pre-existing cardiac disease. Of the 17 patients who died, the past medical history was reported in 12 cases. Of those, 8/12 (75%) had comorbidities.Conclusion: Whilst only a small number of children suffer from COVID-19 disease compared to adults, children with comorbidities, particularly pre-existing cardiac conditions, represent a large proportion of those that became critically unwell. What is Known: • Children are less severely affected by SARS-CoV-2 than adults. • There are reports of children becoming critically unwell with SARS-CoV-2 and requiring intensive care. What is New: • The majority of children who required ventilation for SARS-CoV-2 infection had underlying comorbidities. • The commonest category of comorbidity in these patients was underlying cardiac disease.
    MeSH term(s) Adolescent ; COVID-19/diagnosis ; COVID-19/epidemiology ; Child ; Comorbidity ; Critical Illness ; Global Health ; Humans ; Prognosis ; Risk Factors ; Severity of Illness Index
    Keywords covid19
    Language English
    Publishing date 2020-09-10
    Publishing country Germany
    Document type Journal Article ; Systematic Review
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-020-03801-6
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  7. Article ; Online: Multi-system inflammatory syndrome in children & adolescents (MIS-C): A systematic review of clinical features and presentation.

    Radia, Trisha / Williams, Nia / Agrawal, Pankaj / Harman, Katharine / Weale, Jonathan / Cook, James / Gupta, Atul

    Paediatric respiratory reviews

    2020  Volume 38, Page(s) 51–57

    Abstract: Multisystem Inflammatory Syndrome in Children (MIS-C) is a new phenomenon reported worldwide with temporal association with Covid-19. The objective of this paper is to evaluate reported cases in children and adolescents. From 1726 papers, 35 documented ... ...

    Abstract Multisystem Inflammatory Syndrome in Children (MIS-C) is a new phenomenon reported worldwide with temporal association with Covid-19. The objective of this paper is to evaluate reported cases in children and adolescents. From 1726 papers, 35 documented papers related to MIS-C cases identified 783 individual cases of MIS-C between March-June 2020; with 55% being male (n = 435) and a median age of 8.6 years (IQR, 7-10 years; range 3 months-20 years). Patients with MIS-C were noted to have a high frequency of gastrointestinal symptoms (71%) including abdominal pain (34%) and diarrhea (27%). Cough and respiratory distress were reported in 4.5% and 9.6% cases respectively. Blood parameters showed neutrophilia in 345/418 (83%) of cases and a high CRP in 587/626 (94%). 362/619 (59%) cases were SARS-CoV-2 infection positive (serology or PCR) however only 41% demonstrated pulmonary changes on chest imaging. Severity of illness was high with 68% cases requiring intensive care admission; 63% requiring inotropic support; 244/783 (28%) cases needing some form of respiratory support (138 mechanically ventilated), and 31 required extra-corporeal membrane oxygenation. Treatment strategies included intravenous immunoglobulin (63%) and intravenous steroids (44%). 29 cases received Infliximab, 47 received IL1 (interleukin) receptor antagonist, and 47 received IL6-receptor antagonist. 12/783 (1.5%) children died. In summary, a higher incidence of gastrointestinal symptoms were noted in MIS-C. In contrast to acute Covid-19 infection in children, MIS-C appears to be a condition of higher severity with 68% of cases having required critical care support.
    MeSH term(s) Adolescent ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/therapy ; Child ; Female ; Humans ; Male ; Systemic Inflammatory Response Syndrome/complications ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/therapy
    Keywords covid19
    Language English
    Publishing date 2020-08-11
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2147664-0
    ISSN 1526-0550 ; 1526-0542
    ISSN (online) 1526-0550
    ISSN 1526-0542
    DOI 10.1016/j.prrv.2020.08.001
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  8. Article ; Online: Ethnicity and COVID-19 in children with comorbidities.

    Harman, Katharine / Verma, Anita / Cook, James / Radia, Trisha / Zuckerman, Mark / Deep, Akash / Dhawan, Anil / Gupta, Atul

    The Lancet. Child & adolescent health

    2020  Volume 4, Issue 7, Page(s) e24–e25

    MeSH term(s) Adolescent ; Betacoronavirus ; COVID-19 ; Child ; Child, Preschool ; Chronic Disease/ethnology ; Comorbidity ; Coronavirus Infections/ethnology ; Ethnic Groups/statistics & numerical data ; Female ; Health Status Disparities ; Humans ; Male ; Pandemics ; Pneumonia, Viral/ethnology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country England
    Document type Letter
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(20)30167-X
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  9. Article: Ethnicity and COVID-19 in children with comorbidities

    Harman, Katharine / Verma, Anita / Cook, James / Radia, Trisha / Zuckerman, Mark / Deep, Akash / Dhawan, Anil / Gupta, Atul

    Lancet Child Adolesc Health

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #401776
    Database COVID19

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  10. Article ; Online: Ethnicity and COVID-19 in children with comorbidities

    Harman, Katharine / Verma, Anita / Cook, James / Radia, Trisha / Zuckerman, Mark / Deep, Akash / Dhawan, Anil / Gupta, Atul

    The Lancet Child & Adolescent Health

    2020  Volume 4, Issue 7, Page(s) e24–e25

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2352-4642
    DOI 10.1016/s2352-4642(20)30167-x
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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