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  1. Article ; Online: Correction to "Electrochemical Oxidation of Δ

    Darzi, Evan R / Garg, Neil K

    Organic letters

    2023  Volume 25, Issue 43, Page(s) 7946

    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Published Erratum
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c02968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online ; E-Book: Handbook of Inpatient Endocrinology

    Garg, Rajesh K. / Hennessey, James V. / Malabanan, Alan Ona / Garber, Jeffrey R.

    2020  

    Abstract: A user-friendly, pocket-sized reference for all physicians faced with endocrine care and challenges in hospitalized patients, this handbook covers the most common issues leading to an inpatient endocrine consult, providing differential diagnoses, a ... ...

    Author's details edited by Rajesh K. Garg, James V. Hennessey, Alan Ona Malabanan, Jeffrey R. Garber
    Abstract A user-friendly, pocket-sized reference for all physicians faced with endocrine care and challenges in hospitalized patients, this handbook covers the most common issues leading to an inpatient endocrine consult, providing differential diagnoses, a reasonable and practical approach to investigating and managing the condition, and advice for follow-up. Conditions discussed include thyrotoxicosis and thyroid storm, calcium disorders, osteoporosis, Cushing's syndrome, pheochromocytoma and paraganglioma, primary hyperaldosteronism, hypoglycemia in diabetic and non-diabetic patients, and endocrine issues during pregnancy, among others. Suggestions for further reading are included, providing more context for well-established clinical approaches. Written by experts with years of experience providing endocrinology consultations in a hospital setting, Handbook of Inpatient Endocrinology is a valuable, high-yield resource for endocrine residents and fellows, but it will be equally useful for any busy hospitalist or primary care physician when endocrinology consults are not available.
    Keywords Endocrinology  ; Critical care medicine ; Endocrinology ; Intensive / Critical Care Medicine ; Malalties de les glàndules endocrines ; Pacients ; Endocrinologia
    Subject code 616.4
    Language English
    Size 1 online resource (XVI, 364 p. 12 illus., 5 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-38976-6 ; 3-030-38975-8 ; 978-3-030-38976-5 ; 978-3-030-38975-8
    DOI 10.1007/978-3-030-38976-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Conference proceedings ; Online: Analysis of spatiotemporal variations in surface temperature and thermal comfort level hotspots for Dehradun, India using Landsat series of satellites

    Mishra, K. / Garg, R.

    XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

    2023  

    Abstract: Unprecedented infrastructure creation and unchecked migration from rural areas have caused considerable warming of Dehradun’s urban environment. Estimating the distribution of high and low surface temperature (ST) and thermal comfort level (TCL) clusters ...

    Abstract Unprecedented infrastructure creation and unchecked migration from rural areas have caused considerable warming of Dehradun’s urban environment. Estimating the distribution of high and low surface temperature (ST) and thermal comfort level (TCL) clusters over space and time through satellite-derived measurements is needed to formulate a heat mitigation strategy for the long-term sustenance of the rapid development of this northwestern Himalayan city. Thirty-one cloud-free Landsat-5 and 8 images have been used herein to retrieve ST for winter, summer, monsoon and post-monsoon seasons of 1991, 1998, 2008 and 2018. Using the Anselin Local Moran's I and optimized Getis-Ord GI* statistics, ST hotspots and coldspots have been determined, whereas land surface temperature variation index (LSTVI) has been used to estimate the TCL. Findings indicate an increase of over 9 °C in the average ST per season during these twenty-seven years. The number of hotspots and the area under them has increased consistently from 1991 to 2018. Predominant in the city core, these hotspots have spread with the city’s southward expansion in the southwest-southest direction, while coldspots are retained in the isolated densely vegetated pockets of the north, west and east. A seasonal impact on the ST’s intensity is evident in the hotspots and coldspots with extremes in summer and winter. LSTVI categorization puts more than 50% of the city area under worst TCL conditions, with a continuous areal increment in the considered timeframe. These observations necessitate immediate overhauling of recent policies on developmental activities in the identified areas to prevent future hydroclimatological disasters.
    Language English
    Publishing date 2023-07-11
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Unravelling Differential DNA Methylation Patterns in Genotype Dependent Manner under Salinity Stress Response in Chickpea.

    Gupta, Khushboo / Garg, Rohini

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: DNA methylation is one of the epigenetic mechanisms that govern gene regulation in response to abiotic stress in plants. Here, we analyzed the role of epigenetic variations by exploring global DNA methylation and integrating it with differential gene ... ...

    Abstract DNA methylation is one of the epigenetic mechanisms that govern gene regulation in response to abiotic stress in plants. Here, we analyzed the role of epigenetic variations by exploring global DNA methylation and integrating it with differential gene expression in response to salinity stress in tolerant and sensitive chickpea genotypes. Genome-wide DNA methylation profiles showed higher CG methylation in the gene body regions and higher CHH methylation in the TE body regions. The analysis of differentially methylated regions (DMRs) suggested more hyper-methylation in response to stress in the tolerant genotype compared to the sensitive genotype. We observed higher enrichment of CG DMRs in genes and CHH DMRs in transposable elements (TEs). A positive correlation of gene expression with CG gene body methylation was observed. The enrichment analysis of DMR-associated differentially expressed genes revealed they are involved in biological processes, such as lateral root development, transmembrane transporter activity, GTPase activity, and regulation of gene expression. Further, a high correlation of CG methylation with CHG and CHH methylation under salinity stress was revealed, suggesting crosstalk among the methylation contexts. Further, we observed small RNA-mediated CHH hypermethylation in TEs. Overall, the interplay between DNA methylation, small RNAs, and gene expression provides new insights into the regulatory mechanism underlying salinity stress response in chickpeas.
    MeSH term(s) DNA Methylation ; Cicer/genetics ; Salt Stress/genetics ; Genotype ; Biological Phenomena ; Gene Expression Regulation, Plant
    Language English
    Publishing date 2023-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24031863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Knowledge, attitude, and practices about breast cancer among women in a high-altitude sub-Himalayan region: Are we reaching the unreached?

    Choudhary, Deepti / Lata, Kirti / Thapliyal, Mamta / Tiwari, Ajeet R / Kumar, Rahul / Garg, Pankaj K

    Journal of family medicine and primary care

    2024  Volume 13, Issue 2, Page(s) 743–747

    Abstract: Background: Breast cancer awareness and early detection are critical for reducing the global burden of the disease. This study assessed breast cancer awareness among women in a high-altitude sub-Himalayan region of North India.: Materials and methods!# ...

    Abstract Background: Breast cancer awareness and early detection are critical for reducing the global burden of the disease. This study assessed breast cancer awareness among women in a high-altitude sub-Himalayan region of North India.
    Materials and methods: A cross-sectional survey was conducted among women attending the gynecology outpatient clinic in a district hospital. A structured questionnaire was used to collect data on breast cancer knowledge, attitudes, and practices. Participants received posttest health education and counseling on breast cancer prevention strategies.
    Result: The study included 188 participants with a mean age of 31.0 ± 8.8 years. The findings revealed inadequate knowledge about breast cancer among a significant portion of the cohort. Misconceptions about risk factors, such as breastfeeding, oral contraceptive use, and past wrongdoings, were observed. Only half of the participants believed early-stage breast cancer could be effectively treated. Limited awareness of screening methods, including self-breast examination and mammography, was noted. Barriers to breast self-examination (BSE) included considering it unnecessary and lacking knowledge about its execution.
    Conclusion: This study highlights insufficient breast cancer awareness in the high-altitude sub-Himalayan region. Targeted interventions, including health campaigns and electronic media, should be prioritized to improve knowledge and promote early detection practices.
    Language English
    Publishing date 2024-03-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_1326_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Insight into the Natural Biomolecules (BMs): Promising Candidates as Zika Virus Inhibitors.

    Dobhal, Kiran / Garg, Ruchika / Singh, Alka / Semwal, Amit

    Infectious disorders drug targets

    2024  

    Abstract: Zika virus (ZIKV) is among the relatively new infectious disease threats that include SARS-CoV2, coronavirus, monkeypox (Mpox) virus, etc. ZIKV has been reported to cause severe health risks to the fetus. To date, satisfactory treatment is still not ... ...

    Abstract Zika virus (ZIKV) is among the relatively new infectious disease threats that include SARS-CoV2, coronavirus, monkeypox (Mpox) virus, etc. ZIKV has been reported to cause severe health risks to the fetus. To date, satisfactory treatment is still not available for the treatment of ZIKV infection. This review examines the last five years of work using natural biomolecules (BMs) to counteract the ZIKV through virtual screening and in vitro investigations. Virtual screening has identified doramectin, pinocembrin, hesperidins, epigallocatechin gallate, pedalitin, and quercetin as potentially active versus ZIKV infection. In vitro, testing has shown that nordihydroguaiaretic acid, mefloquine, isoquercitrin, glycyrrhetinic acid, patentiflorin-A, rottlerin, and harringtonine can reduce ZIKV infections in cell lines. However, in vivo, testing is limited, fortunately, emetine, rottlerin, patentiflorin-A, and lycorine have shown in vivo anti- ZIKV potential. This review focuses on natural biomolecules that show a particularly high selective index (>10). There is limited in vivo and clinical trial data for natural BMs, which needs to be an active area of investigation. This review aims to compile the known reference data and discuss the barriers associated with discovering and using natural BM agents to control ZIKV infection.
    Language English
    Publishing date 2024-02-02
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2234298-9
    ISSN 2212-3989 ; 1871-5265
    ISSN (online) 2212-3989
    ISSN 1871-5265
    DOI 10.2174/0118715265272414231226092146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5598: Show issues Location:
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  7. Article ; Online: True mesothelial cyst of the adrenal gland: its clinical profile and management.

    Saini, Vikram / Garg, Richa / Kataria, Kamal / Nelson, Thirugnanasambandam

    BMJ case reports

    2024  Volume 17, Issue 2

    Abstract: The incidence of adrenal cysts is 0.06% and only 9% of these are true mesothelial cysts. Here, we present a case of a true mesothelial cyst together with a review of the literature. A female in her 30s presented to the surgical outpatient department ... ...

    Abstract The incidence of adrenal cysts is 0.06% and only 9% of these are true mesothelial cysts. Here, we present a case of a true mesothelial cyst together with a review of the literature. A female in her 30s presented to the surgical outpatient department complaining of right flank pain. Her contrast-enhanced CT scan revealed a 7.5×6.5×4.5 cm right adrenal gland cyst. The patient underwent a laparoscopic right adrenalectomy. Immunohistopathology revealed the cyst to be mesothelial in nature. The majority of true mesothelial adrenal cysts are benign, unilateral and more common in women. Any adrenal cyst diagnosed as a functional lesion or one that may be malignant or with a diameter of 5 cm or greater requires surgical care whereas smaller lesions can be managed conservatively. Laparoscopic adrenalectomy for an adrenal cyst of diameter greater than 6 cm is a safe and feasible procedure in expert hands if there is no invasion of surrounding tissue.
    MeSH term(s) Humans ; Female ; Adrenal Gland Diseases/diagnostic imaging ; Adrenal Gland Diseases/surgery ; Adrenal Glands/diagnostic imaging ; Adrenal Glands/surgery ; Adrenal Glands/pathology ; Cysts/diagnostic imaging ; Cysts/surgery ; Adrenal Gland Neoplasms/surgery ; Adrenalectomy/methods ; Laparoscopy
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-258485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An innovative reconstruction of an enbloc resected composite giant chest and abdominal wall chondrosarcoma with 3D-composite mesh.

    Dantis, Klein / Singh, Ramandeep / Goel, Archit / Garg, Brijesh

    Journal of cardiothoracic surgery

    2024  Volume 19, Issue 1, Page(s) 126

    Abstract: Background: Chest wall chondrosarcomas, although common, pose unique challenges due to their aggressive nature, rarity of abdominal wall involvement, and propensity for recurrence. We highlight the critical role of meticulous surgical planning, ... ...

    Abstract Background: Chest wall chondrosarcomas, although common, pose unique challenges due to their aggressive nature, rarity of abdominal wall involvement, and propensity for recurrence. We highlight the critical role of meticulous surgical planning, multidisciplinary collaboration, and innovative reconstruction techniques in achieving optimal outcomes for patients with composite giant chest and abdominal wall chondrosarcoma.
    Case presentation: A 38-year-old female patient presented with progressive left chest and abdominal wall swelling for two years; on evaluation had a large lobulated lytic lesion arising from the left ninth rib, scalloping eighth and tenth ribs measuring 13.34 × 8.92 × 10.71 cm (anteroposterior/transverse/craniocaudal diameter) diagnosed with chondrosarcoma grade 2. A three-dimensional (3D) composite mesh was designed based on computed tomography using virtual surgical planning and computer-assisted design and manufacturing technology. She underwent wide local excision and reconstruction of the chest and abdominal wall with 3D-composite mesh under general anesthesia. The postoperative condition was uneventful, with no recurrence at 12 months follow-up.
    Conclusion: A 3D-composite mesh facilitates patient-specific, durable, and cost-effective chest and abdominal wall reconstruction.
    MeSH term(s) Female ; Humans ; Adult ; Plastic Surgery Procedures ; Abdominal Wall/surgery ; Abdominal Wall/pathology ; Surgical Mesh ; Thoracic Wall/surgery ; Thoracic Wall/pathology ; Chondrosarcoma/diagnostic imaging ; Chondrosarcoma/surgery ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/surgery ; Bone Neoplasms/pathology
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2227224-0
    ISSN 1749-8090 ; 1749-8090
    ISSN (online) 1749-8090
    ISSN 1749-8090
    DOI 10.1186/s13019-024-02595-0
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  9. Article: How to make your Abstract noticeable during submission for paper presentation in a Conference: Points to ponder!!!

    Ahuja, Vanita / Theerth, Kaushic / Garg, Rakesh

    Indian journal of anaesthesia

    2024  Volume 68, Issue Suppl 1, Page(s) S6–S7

    Language English
    Publishing date 2024-02-23
    Publishing country India
    Document type Editorial
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_165_24
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1841: Show issues Location:
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  10. Article ; Online: Weight Gain and Glycemic Control in Adults with Type 1 Diabetes in the T1D Exchange Registry.

    Bailey, Ryan / Calhoun, Peter / Garg, Satish K

    Diabetes technology & therapeutics

    2024  Volume 26, Issue 3, Page(s) 156–160

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Adult ; Female ; Humans ; Male ; Diabetes Mellitus, Type 1/drug therapy ; Blood Glucose ; Glycated Hemoglobin ; Glycemic Control ; Registries ; Insulin, Regular, Human ; Insulin/therapeutic use ; Weight Gain
    Chemical Substances Blood Glucose ; Glycated Hemoglobin ; Insulin, Regular, Human ; Insulin
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2023.0389
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    Zs.A 5269: Show issues Location:
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