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Article ; Online: Estimating morning and evening commute period O

Hsu, Chin-Yu / Lee, Ruei-Qin / Wong, Pei-Yi / Candice Lung, Shih-Chun / Chen, Yu-Cheng / Chen, Pau-Chung / Adamkiewicz, Gary / Wu, Chih-Da

Journal of environmental management

2023 Volume 351, Page(s) 119725

Abstract: Elevated levels of ground-level ozone (O ...

Abstract	Elevated levels of ground-level ozone (O
MeSH term(s)	Air Pollutants/analysis ; Artificial Intelligence ; Environmental Monitoring/methods ; Taiwan ; Air Pollution/analysis ; Particulate Matter/analysis
Chemical Substances	Air Pollutants ; Particulate Matter
Language	English
Publishing date	2023-12-07
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.119725
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Article ; Online: Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules.

Ma, Bowen / Khan, Khadija Shahed / Xu, Tongyang / Xeque Amada, Josefina / Guo, Zhihao / Huang, Yunpeng / Yan, Yu / Lam, Henry / Cheng, Alfred Sze-Lok / Ng, Billy Wai-Lung

Journal of the American Chemical Society

2024 Volume 146, Issue 14, Page(s) 9779–9789

Abstract: Protein O-linked β- ...

Abstract	Protein O-linked β-
MeSH term(s)	Humans ; Nuclear Proteins/metabolism ; Transcription Factors/metabolism ; Protein Processing, Post-Translational ; Neoplasms ; N-Acetylglucosaminyltransferases/metabolism ; Acetylglucosamine/metabolism ; Bromodomain Containing Proteins ; Cell Cycle Proteins/metabolism
Chemical Substances	Nuclear Proteins ; Transcription Factors ; N-Acetylglucosaminyltransferases (EC 2.4.1.-) ; Acetylglucosamine (V956696549) ; BRD4 protein, human ; Bromodomain Containing Proteins ; Cell Cycle Proteins
Language	English
Publishing date	2024-04-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c14380
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Article ; Online: Photolysis of O

Chou, Sheng-Lung / Lo, Jen-Iu / Peng, Yu-Chain / Lu, Hsiao-Chi / Cheng, Bing-Ming / Ogilvie, J F

Physical chemistry chemical physics : PCCP

2018 Volume 20, Issue 11, Page(s) 7730–7738

Abstract: Irradiation at 173 or 143 nm of samples ... ...

Abstract	Irradiation at 173 or 143 nm of samples of
Language	English
Publishing date	2018-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/c8cp00078f
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Article ; Online: Thresholds of photolysis of O

Lo, Jen-Iu / Chou, Sheng-Lung / Peng, Yu-Chain / Lu, Hsiao-Chi / Ogilvie, J F / Cheng, Bing-Ming

Physical chemistry chemical physics : PCCP

2018 Volume 20, Issue 19, Page(s) 13113–13117

Abstract: ... of O3 and emission lines from atomic O (1D2 → 3P1,2), molecular O2 (A' 3Δu → X 3Σg) and radical OH ... hence the threshold for dissociation of O2. The thresholds of emission from excited O (1D2), O2 (A' 3Δu) and OH (A 2Σ+ ... The results indicate that, once O3 was generated, it was readily photolyzed to produce the long-lived atom O ...

Abstract	Irradiation of O2 dispersed in solid Ne with ultraviolet light produced infrared absorption lines of O3 and emission lines from atomic O (1D2 → 3P1,2), molecular O2 (A' 3Δu → X 3Σg) and radical OH (A 2Σ+ → X 2ΠI) in the visible and near-ultraviolet regions. The threshold wavelength for the formation of O3 was determined to be 200 ± 4 nm, corresponding to energy 6.20 ± 0.12 eV, which is hence the threshold for dissociation of O2. The thresholds of emission from excited O (1D2), O2 (A' 3Δu) and OH (A 2Σ+) were all observed to be 200 ± 4 nm, the same as for the formation of O3 in this photochemical system. The results indicate that, once O3 was generated, it was readily photolyzed to produce the long-lived atom O (1D2). Further reactions of O (1D2) with O3 produced excited O2 (A' 3Δu); reaction with water yielded radical OH (A 2Σ+). These results enhance our understanding of the evolution of the transformation of oxygen and open a window for the understanding of complicated processes in the solid phase.
Language	English
Publishing date	2018-05-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/c8cp01375f
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Article ; Online: Omics and mechanistic insights into di-(2-ethylhexyl) phthalate degradation in the O

Wang, Po-Hsiang / Chen, Yi-Lung / Wu, Tien-Yu / Wu, Yu-Wei / Wang, Tzi-Yuan / Shih, Chao-Jen / Wei, Sean Ting-Shyang / Lai, Yi-Li / Liu, Cheng-Xuan / Chiang, Yin-Ru

Chemosphere

2022 Volume 299, Page(s) 134406

Abstract: ... this bottleneck and deconstructed the microbial synergy in O ...

Abstract	Di-(2-ethylhexyl) phthalate (DEHP) represents the most used phthalate plasticizer with an annual production above the millions of tons worldwide. Due to its inadequate disposal, outstanding chemical stability, and extremely low solubility (3 mg/L), endocrine-disrupting DEHP often accumulates in urban estuarine sediments at concentrations above the predicted no-effect concentration (20-100 mg/kg). Our previous study suggested that microbial DEHP degradation in estuarine sediments proceeds synergistically where DEHP side-chain hydrolysis to form phthalic acid represents a bottleneck. Here, we resolved this bottleneck and deconstructed the microbial synergy in O
MeSH term(s)	Biodegradation, Environmental ; Diethylhexyl Phthalate/metabolism ; Phthalic Acids/metabolism ; Thauera
Chemical Substances	Phthalic Acids ; phthalic acid (6O7F7IX66E) ; Diethylhexyl Phthalate (C42K0PH13C)
Language	English
Publishing date	2022-03-28
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2022.134406
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Article ; Online: Synthesis and Characterization of MWCNT-COOH/Fe 3 O 4 and CNT-COOH/Fe 3 O 4 /NiO Nanocomposites

Adina Stegarescu / Humberto Cabrera / Hanna Budasheva / Maria-Loredana Soran / Ildiko Lung / Francesca Limosani / Dorota Korte / Matteo Amati / Gheorghe Borodi / Irina Kacso / Ocsana Opriş / Monica Dan / Stefano Bellucci

Nanomaterials, Vol 12, Iss 3008, p

Assessment of Adsorption and Photocatalytic Performance

2022 Volume 3008

Abstract: ... carbon nanotubes (MWCNTs), using tartrazine as a model pollutant, is demonstrated. MWCNT-COOH/Fe 3 O 4 and MWCNT ... COOH/Fe 3 O 4 /NiO nanocomposites were prepared by precipitation of metal oxides in the presence ... analysis. It was found that the optimal adsorption conditions were pH 4 for MWCNT-COOH/Fe 3 O 4 and pH 3 ...

Abstract	In this study the adsorption and photodegradation capabilities of modified multi-walled carbon nanotubes (MWCNTs), using tartrazine as a model pollutant, is demonstrated. MWCNT-COOH/Fe 3 O 4 and MWCNT-COOH/Fe 3 O 4 /NiO nanocomposites were prepared by precipitation of metal oxides in the presence of MWCNTs. Their properties were examined by X-ray diffraction in powder (XRD), Fourier-transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), Raman spectroscopy, synchrotron-based Scanning PhotoElectron Microscopy (SPEM), and Brunauer-Emmett-Teller (BET) analysis. It was found that the optimal adsorption conditions were pH 4 for MWCNT-COOH/Fe 3 O 4 and pH 3 for MWCNT-COOH/Fe 3 O 4 /NiO, temperature 25 °C, adsorbent dose 1 g L −1 , initial concentration of tartrazine 5 mg L −1 for MWCNT-COOH/Fe 3 O 4 and 10 mg L −1 for MWCNT-COOH/Fe 3 O 4 /NiO and contact time 5 min for MWCNT-COOH/Fe 3 O 4 /NiO and 15 min for MWCNT-COOH/Fe 3 O 4 . Moreover, the predominant degradation process was elucidated simultaneously, with and without simulated sunlight irradiation, using thermal lens spectrometry (TLS) and UV–Vis absorption spectrophotometry. The results indicated the prevalence of the photodegradation mechanism over adsorption from the beginning of the degradation process.
Keywords	carbon nanotubes ; magnetite ; tartrazine ; photodegradation ; adsorption ; water decontamination ; Chemistry ; QD1-999
Subject code	290 ; 669
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article: Understanding the formation mechanism of consumers' behavioral intention on Double 11 shopping carnival: Integrating S-O-R and ELM theories.

Shiau, Wen-Lung / Zhou, Mengru / Liu, Chang

Frontiers in psychology

2022 Volume 13, Page(s) 984272

Abstract: ... likelihood model (ELM) and stimulus-organism-response (S-O-R) theory to study the dual-processing path ...

Abstract	Double 11 shopping carnival, celebrated by the most successful electronic-commerce (e-commerce) Chinese company, Alibaba, has always been the online shopping festival with the highest turnover and involves the largest number of consumers and enterprises in China. This study integrates the elaboration likelihood model (ELM) and stimulus-organism-response (S-O-R) theory to study the dual-processing path of information, which drives customers' behavioral intention on Double 11. There are 454 valid samples of data are collected, and the research model is tested using the partial least squares method. Results show that in the Double 11 context, two different processing mechanisms affect consumers' behavioral intention. Thereinto, consumers' behavioral intention is more affected by the peripheral path than the central path. The affective experience affected by the information stimulus has a greater impact on the behavioral intention than cognitive experience. Furthermore, we find situational involvement have different moderating effects on the relationship between two experiences and behavioral intention.
Language	English
Publishing date	2022-09-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.984272
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Article ; Online: The Effect of Annealing Ambience on the Material and Photodetector Characteristics of Sputtered ZnGa 2 O 4 Films

Anoop Kumar Singh / Shiau-Yuan Huang / Po-Wei Chen / Jung-Lung Chiang / Dong-Sing Wuu

Nanomaterials, Vol 11, Iss 2316, p

2021 Volume 2316

Abstract: Spinel ZnGa 2 O 4 films were grown on c-plane sapphire substrates at the substrate temperature ... on the microstructural and optoelectronic properties of ZnGa 2 O 4 films was systematically investigated in various ... ambiences, such as air, nitrogen, and oxygen. The X-ray diffraction patterns of annealed ZnGa 2 O 4 films ...

Abstract	Spinel ZnGa 2 O 4 films were grown on c-plane sapphire substrates at the substrate temperature of 400 °C by radio-frequency magnetron sputtering. Post thermal annealing was employed at the annealing temperature of 700 °C in order to enhance their crystal quality. The effect of thermal annealing on the microstructural and optoelectronic properties of ZnGa 2 O 4 films was systematically investigated in various ambiences, such as air, nitrogen, and oxygen. The X-ray diffraction patterns of annealed ZnGa 2 O 4 films showed the crystalline structure to have (111) crystallographic planes. Transmission electron micrographs verified that ZnGa 2 O 4 film annealed under air ambience possesses a quasi-single-crystalline structure. This ZnGa 2 O 4 film annealed under air ambience exhibited a smooth surface, an excellent average transmittance above 82% in the visible region, and a wide bandgap of 5.05 eV. The oxygen vacancies under different annealing ambiences were revealed a substantial impact on the material and photodetector characteristics by X-ray photoelectron spectrum investigations. ZnGa 2 O 4 film exhibits optimal performance as a metal-semiconductor-metal photodetector when annealed under air ambience. Under these conditions, ZnGa 2 O 4 film exhibits a higher photo/dark current ratio of ~10 4 order, as well as a high responsivity of 2.53 A/W at the bias of 5 V under an incident optical light of 240 nm. These results demonstrate that quasi-single-crystalline ZnGa 2 O 4 films have significant potential in deep-ultraviolet applications.
Keywords	ZnGa 2 O 4 ; annealing ambience ; wide bandgap ; metal-semiconductor-metal photodetector ; responsivity ; Chemistry ; QD1-999
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Auramine O, an incense smoke ingredient, promotes lung cancer malignancy.

Tung, Jia-Chen / Huang, Wei-Chien / Yang, Juan-Cheng / Chen, Guan-Yu / Fan, Chi-Chen / Chien, Yu-Chuan / Lin, Pei-Shan / Candice Lung, Shih-Chun / Chang, Wei-Chao

Environmental toxicology

2017 Volume 32, Issue 11, Page(s) 2379–2391

Abstract: ... of lung cancer. Based on this hypothesis, we identified a major compound auramine O (AuO) from the water-soluble ... between burning incense and lung cancer in epidemiological studies remains controversy ... effect on malignant transformation; but, it dramatically promotes lung cancer malignancy. AuO accumulates ...

Abstract	Burning incense to worship deities is a popular religious ritual in large parts of Asia, and is a popular custom affecting more than 1.5 billion adherents. Due to incomplete combustion, burning incense has been well recognized to generate airborne hazards to human health. However, the correlation between burning incense and lung cancer in epidemiological studies remains controversy. Therefore, we speculated that some unknown materials in incense smoke are involved in the initiation or progression of lung cancer. Based on this hypothesis, we identified a major compound auramine O (AuO) from the water-soluble fraction of incense burned condensate using mass spectrometry. AuO is commonly used in incense manufacture as a colorant. Due to thermostable, AuO released from burned incenses becomes an unexpected air pollutant. AuO is classified as a Group 2B chemical by the International Agency of Research on Cancer (IARC), however, the damage of AuO to the respiratory system remains elusive. Our study revealed that AuO has no apparent effect on malignant transformation; but, it dramatically promotes lung cancer malignancy. AuO accumulates in the nucleus and induces the autophagy activity in lung tumor cells. AuO significantly enhances migration and invasive abilities and the in vitro and in vivo stemness features of lung tumor cells through activating the expression of aldehyde dehydrogenase family 1 member A1 (ALDH1A1), and ALDH1A1 knockdown attenuates AuO-induced autophagy activity and blocks AuO-induced lung tumor malignancy. In conclusion, we found that AuO, an ingredient of incense smoke, significantly increases the metastatic abilities and stemness characters of lung tumor cells through the activation of ALDH1A1, which is known to be associated with poor outcome and progression of lung cancer. For public health, reducing or avoiding the use of AuO in incense is recommended.
MeSH term(s)	Adenocarcinoma/chemically induced ; Adenocarcinoma/pathology ; Adenocarcinoma of Lung ; Air Pollutants/analysis ; Air Pollutants/toxicity ; Air Pollution, Indoor ; Aldehyde Dehydrogenase/genetics ; Aldehyde Dehydrogenase/metabolism ; Aldehyde Dehydrogenase 1 Family ; Animals ; Benzophenoneidum/toxicity ; Cell Line, Tumor ; Coloring Agents/toxicity ; Epithelial Cells/drug effects ; Epithelial Cells/pathology ; Humans ; Lung Neoplasms/chemically induced ; Lung Neoplasms/pathology ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Metastasis ; Respiratory Mucosa/drug effects ; Respiratory Mucosa/pathology ; Retinal Dehydrogenase ; Smoke/adverse effects ; Smoke/analysis ; Spheroids, Cellular/pathology
Chemical Substances	Air Pollutants ; Coloring Agents ; Smoke ; Benzophenoneidum (2465-27-2) ; Aldehyde Dehydrogenase 1 Family (EC 1.2.1) ; Aldehyde Dehydrogenase (EC 1.2.1.3) ; ALDH1A1 protein, human (EC 1.2.1.36) ; Retinal Dehydrogenase (EC 1.2.1.36)
Language	English
Publishing date	2017-07-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	1463449-1
ISSN	1522-7278 ; 1520-4081
ISSN (online)	1522-7278
ISSN	1520-4081
DOI	10.1002/tox.22451
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Zs.A 2676: Show issues

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Article ; Online: O-Glycosylation-mediated signaling circuit drives metastatic castration-resistant prostate cancer.

Tzeng, Sheue-Fen / Tsai, Chin-Hsien / Chao, Tai-Kuang / Chou, Yu-Ching / Yang, Yu-Chih / Tsai, Mong-Hsun / Cha, Tai-Lung / Hsiao, Pei-Wen

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

2018 , Page(s) fj201800687

Abstract: ... sialyltransferase 1 (ST3GAL1), and resulting mucin-type O-glycans during the progression of CRPC. Furthermore ... galectin-4 engaged with C1GALT1-dependent O-glycans to promote castration resistance and metastasis ... cellular mucin-type O-glycosylation to allow for galectin-4 binding. In clinical prostate cancer, high ...

Abstract	Disseminated castration-resistant prostate cancer (CRPC) is a common disease in men that is characterized by limited survival and resistance to androgen-deprivation therapy. The increase in human epidermal growth factor receptor 2 (HER2) signaling contributes to androgen receptor activity in a subset of patients with CRPC; however, enigmatically, HER2-targeted therapies have demonstrated a lack of efficacy in patients with CRPC. Aberrant glycosylation is a hallmark of cancer and involves key processes that support cancer progression. Using transcriptomic analysis of prostate cancer data sets, histopathologic examination of clinical specimens, and in vivo experiments of xenograft models, we reveal in this study a coordinated increase in glycan-binding protein, galectin-4, specific glycosyltransferases of core 1 synthase, glycoprotein- N-acetylgalactosamine 3-β-galactosyltransferase 1 (C1GALT1) and ST3 beta-galactoside α-2,3-sialyltransferase 1 (ST3GAL1), and resulting mucin-type O-glycans during the progression of CRPC. Furthermore, galectin-4 engaged with C1GALT1-dependent O-glycans to promote castration resistance and metastasis by activating receptor tyrosine kinase signaling and cancer cell stemness properties mediated by SRY-box 9 (SOX9). This galectin-glycan interaction up-regulated the MYC-dependent expression of C1GALT1 and ST3GAL1, which altered cellular mucin-type O-glycosylation to allow for galectin-4 binding. In clinical prostate cancer, high-level expression of C1GALT1 and galectin-4 together predict poor overall survival compared with low-level expression of C1GALT1 and galectin-4. In summary, MYC regulates abnormal O-glycosylation, thus priming cells for binding to galectin-4 and downstream signaling, which promotes castration resistance and metastasis.-Tzeng, S.-F., Tsai, C.-H., Chao, T.-K., Chou, Y.-C., Yang, Y.-C., Tsai, M.-H., Cha, T.-L., Hsiao, P.-W. O-Glycosylation-mediated signaling circuit drives metastatic castration-resistant prostate cancer.
Language	English
Publishing date	2018-06-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	639186-2
ISSN	1530-6860 ; 0892-6638
ISSN (online)	1530-6860
ISSN	0892-6638
DOI	10.1096/fj.201800687
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