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  1. Article: CT-Guided Pericardial Drainage: A Safe and Viable Alternative to Ultrasound-Guided Drainage.

    Ingber, Ross B / Al-Roubaie, Mustafa / Lodhi, Umairullah / Greben, Craig

    Seminars in interventional radiology

    2022  Volume 39, Issue 3, Page(s) 329–333

    Language English
    Publishing date 2022-08-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0042-1751284
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  2. Article ; Online: Comparing Outcomes of CT-Guided Percutaneous Pericardial Drainage with Surgical Pericardial Window in Patients with Symptomatic Pericardial Effusions.

    Ingber, Ross B / Lodhi, Umairullah / Mootz, Joseph / Siegel, Adam / Al-Roubaie, Mustafa / Greben, Craig

    Academic radiology

    2023  Volume 30, Issue 11, Page(s) 2533–2540

    Abstract: Rationale and objectives: To compare short-term outcomes of CT-guided percutaneous pericardial drainage (PPD) versus subxiphoid surgical pericardial window (PW) drainage and analyze the risk factors associated with their outcomes.: Materials and ... ...

    Abstract Rationale and objectives: To compare short-term outcomes of CT-guided percutaneous pericardial drainage (PPD) versus subxiphoid surgical pericardial window (PW) drainage and analyze the risk factors associated with their outcomes.
    Materials and methods: A retrospective chart review of patients who underwent either percutaneous drainage with drainage catheter placement or PW with surgical drain placement for symptomatic pericardial effusion between January 1, 2006 and August 31, 2016 was performed after institutional review board approval (decision number 16-783). The primary objective was to test for associations between the short-term (≤30 days post procedure) complication and recurrence rates in patients with symptomatic pericardial effusions. The secondary objectives were to test for associations between short-term complications with changes in vital signs.
    Results: Of the 257 procedures included in the final analysis, 142 were in the percutaneous drainage group. Short-term complication rate was significantly greater (p < 0.001) in patients undergoing PW, 17% (19/114), as compared with PPD, 2% (3/142). The estimated odds of having complications in the PW cohort was 9 times greater than the percutaneous drainage cohort (OR = 9.3, 95% CI:  2.7-32.3). No significant difference was observed between whether or not a patient experienced a short-term recurrence and any of the explanatory variables (patient demographics, imaging, and vital signs).
    Conclusion: CT-guided PPD is a safer alternative to surgical PW as it leads to fewer complications without a significant difference in recurrence rate of pericardial effusion.
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2023.02.014
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  3. Article: CT-Guided Pericardial Drainage: A Safe and Viable Alternative to Ultrasound-Guided Drainage

    Ingber, Ross B. / Al-Roubaie, Mustafa / Lodhi, Umairullah / Greben, Craig

    Seminars in Interventional Radiology

    (Thoracic Interventions)

    2022  Volume 39, Issue 03, Page(s) 329–333

    Series title Thoracic Interventions
    Language English
    Publishing date 2022-06-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0042-1751284
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  4. Article ; Conference proceedings: A Practical Approach to Performing a Contrast-Enhanced Ultrasound-Guided Percutaneous Liver Biopsy

    Monsuruddin, Shahir / Lodhi, Umairullah / Burke, Brian

    Digestive Disease Interventions

    2019  Volume 03, Issue S 01

    Event/congress Abstracts of 5th Annual Meeting of the American Society of Digestive Disease Interventions, New York, 2018-10-17
    Language English
    Publishing date 2019-03-01
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2472-873X ; 2472-8721
    ISSN (online) 2472-873X
    ISSN 2472-8721
    DOI 10.1055/s-0039-1689036
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  5. Article ; Conference proceedings: Role of Percutaneous Biliary Stenting in Managing High-Grade Malignant Biliary Obstruction

    Lodhi, Umairullah / Isa, Arton / Latzman, Jonathan

    Digestive Disease Interventions

    2019  Volume 03, Issue S 01

    Event/congress Abstracts of 5th Annual Meeting of the American Society of Digestive Disease Interventions, New York, 2018-10-17
    Language English
    Publishing date 2019-03-01
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2472-873X ; 2472-8721
    ISSN (online) 2472-873X
    ISSN 2472-8721
    DOI 10.1055/s-0039-1689035
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  6. Article ; Online: Initial Institutional Experience With Cryoablation Therapy for Breast Fibroadenomas: Technique, Molecular Science, and Post-Therapy Imaging Follow-up.

    Sheth, Monica / Lodhi, Umairullah / Chen, Brandon / Park, Young / McElligott, Suzanne

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2019  Volume 38, Issue 10, Page(s) 2769–2776

    Abstract: Cryoablation is a safe and effective nonsurgical treatment for breast fibroadenomas (FAs). The treatment response is inversely related to the tumor size, with lesions less than 2 cm showing an optimal response. Ultrasound (US) imaging follow-up of the ... ...

    Abstract Cryoablation is a safe and effective nonsurgical treatment for breast fibroadenomas (FAs). The treatment response is inversely related to the tumor size, with lesions less than 2 cm showing an optimal response. Ultrasound (US) imaging follow-up of the ablated tumor is recommended at 6-month intervals for 2 years at our institution. Although a decrease in the size of the FA clinically and on US imaging is the expected treatment response, variations can be seen. Knowledge of typical US changes over time is imperative to prevent unnecessary rebiopsy or excision in patients who have undergone cryoablation. We will review the initial patient selection criteria, cryoablation technique, and US findings at regular follow-up intervals after cryoablation of FAs through a series of cases treated at our institution.
    MeSH term(s) Breast/diagnostic imaging ; Breast/surgery ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/surgery ; Cryosurgery/methods ; Female ; Fibroadenoma/diagnostic imaging ; Fibroadenoma/surgery ; Humans ; Treatment Outcome ; Ultrasonography, Mammary/methods
    Language English
    Publishing date 2019-03-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.14980
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  7. Article: Multisystem Radiologic Manifestations of Erdheim-Chester Disease.

    Lodhi, Umairullah / Sarmast, Uzair / Khan, Saadullah / Yaddanapudi, Kavitha

    Case reports in radiology

    2016  Volume 2016, Page(s) 2670495

    Abstract: Erdheim-Chester Disease is a rare form of multiorgan non-Langerhans' cell histiocytosis that affects individuals between the ages of 50 and 70 with an equal distribution among males and females. It is associated with significant morbidity and mortality ... ...

    Abstract Erdheim-Chester Disease is a rare form of multiorgan non-Langerhans' cell histiocytosis that affects individuals between the ages of 50 and 70 with an equal distribution among males and females. It is associated with significant morbidity and mortality that is mostly due to infiltration of critical organs. Some of the sites that Erdheim-Chester Disease affects include the skeletal system, central nervous system, cardiovascular system, lungs, kidneys (retroperitoneum), and skin. The most common presenting symptom of Erdheim-Chester Disease is bone pain although a large majority of patients are diagnosed incidentally during a workup for a different disease process. Diagnosing Erdheim-Chester Disease is challenging due its rarity and mimicry to other infiltrative processes. Therefore, a multimodality diagnostic approach is employed with imaging being at the forefront. As of date, a comprehensive radiologic review of the manifestations of Erdheim-Chester Disease has rarely been reported. Here we present radiologic findings of an individual suffering from Erdheim-Chester Disease.
    Language English
    Publishing date 2016-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2627655-0
    ISSN 2090-6870 ; 2090-6862
    ISSN (online) 2090-6870
    ISSN 2090-6862
    DOI 10.1155/2016/2670495
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  8. Article ; Online: Multisystem Radiologic Manifestations of Erdheim-Chester Disease

    Umairullah Lodhi / Uzair Sarmast / Saadullah Khan / Kavitha Yaddanapudi

    Case Reports in Radiology, Vol

    2016  Volume 2016

    Abstract: Erdheim-Chester Disease is a rare form of multiorgan non-Langerhans’ cell histiocytosis that affects individuals between the ages of 50 and 70 with an equal distribution among males and females. It is associated with significant morbidity and mortality ... ...

    Abstract Erdheim-Chester Disease is a rare form of multiorgan non-Langerhans’ cell histiocytosis that affects individuals between the ages of 50 and 70 with an equal distribution among males and females. It is associated with significant morbidity and mortality that is mostly due to infiltration of critical organs. Some of the sites that Erdheim-Chester Disease affects include the skeletal system, central nervous system, cardiovascular system, lungs, kidneys (retroperitoneum), and skin. The most common presenting symptom of Erdheim-Chester Disease is bone pain although a large majority of patients are diagnosed incidentally during a workup for a different disease process. Diagnosing Erdheim-Chester Disease is challenging due its rarity and mimicry to other infiltrative processes. Therefore, a multimodality diagnostic approach is employed with imaging being at the forefront. As of date, a comprehensive radiologic review of the manifestations of Erdheim-Chester Disease has rarely been reported. Here we present radiologic findings of an individual suffering from Erdheim-Chester Disease.
    Keywords Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Interferon-α accelerates murine systemic lupus erythematosus in a T cell-dependent manner.

    Liu, Zheng / Bethunaickan, Ramalingam / Huang, Weiqing / Lodhi, Umairullah / Solano, Ingrid / Madaio, Michael P / Davidson, Anne

    Arthritis and rheumatism

    2010  Volume 63, Issue 1, Page(s) 219–229

    Abstract: Objective: To investigate the mechanism by which interferon-α (IFNα) accelerates systemic lupus erythematosus (SLE) in (NZB×NZW)F1 (NZB/NZW) mice.: Methods: NZB/NZW mice were treated with an adenovirus expressing IFNα. In some mice, T cells were ... ...

    Abstract Objective: To investigate the mechanism by which interferon-α (IFNα) accelerates systemic lupus erythematosus (SLE) in (NZB×NZW)F1 (NZB/NZW) mice.
    Methods: NZB/NZW mice were treated with an adenovirus expressing IFNα. In some mice, T cells were depleted with an anti-CD4 antibody. The production of anti-double-stranded DNA (anti-dsDNA) antibodies was measured by enzyme-linked immunosorbent assay and enzyme-linked immunospot assay. Germinal centers and antibody-secreting cells (ASCs) in spleens and IgG deposition and leukocyte infiltrates in kidneys were visualized by immunofluorescence staining. The phenotype of splenic cells was determined by flow cytometry. Finally, somatic hypermutation and gene usage in VH regions of IgG2a and IgG3 were studied by single-cell polymerase chain reaction.
    Results: IFNα-accelerated lupus in NZB/NZW mice was associated with elevated serum levels of IgG2 and IgG3 anti-dsDNA antibodies and accumulation of many IgG ASCs in the spleen, which did not develop into long-lived plasma cells. Furthermore, IgG2a and IgG3 antibodies in the mice were highly somatically mutated and used distinct repertoires of VH genes. The induction of SLE in the mice was associated with an increase in B cell Toll-like receptor 7 expression, increased serum levels of BAFF, interleukin-6 (IL-6), and tumor necrosis factor α, and induction of T cells expressing IL-21. Although IFNα drove a T cell-independent increase in serum levels of IgG, autoantibody induction and the development of nephritis were both completely dependent on CD4+ T cell help.
    Conclusion: These findings demonstrate that, although IFNα activates both innate and adaptive immune responses in NZB/NZW mice, CD4+ T cells are necessary for IFNα-driven induction of anti-dsDNA antibodies and clinical SLE.
    MeSH term(s) Adaptive Immunity/immunology ; Animals ; Autoantibodies/genetics ; Autoantibodies/immunology ; Cytokines/blood ; Cytokines/immunology ; Dependovirus ; Disease Progression ; Enzyme-Linked Immunosorbent Assay ; Female ; Immunity, Innate/immunology ; Immunohistochemistry ; Interferon-alpha/genetics ; Interferon-alpha/immunology ; Lupus Erythematosus, Systemic/blood ; Lupus Erythematosus, Systemic/genetics ; Lupus Erythematosus, Systemic/immunology ; Lupus Erythematosus, Systemic/pathology ; Mice ; Mice, Inbred NZB ; Reverse Transcriptase Polymerase Chain Reaction ; Spleen/immunology ; Spleen/pathology ; Statistics, Nonparametric ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology
    Chemical Substances Autoantibodies ; Cytokines ; Interferon-alpha
    Language English
    Publishing date 2010-10-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 127294-9
    ISSN 1529-0131 ; 0004-3591 ; 2326-5191
    ISSN (online) 1529-0131
    ISSN 0004-3591 ; 2326-5191
    DOI 10.1002/art.30087
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