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  1. Article ; Online: Comparison of outcomes following radiological reduction of intussusception with or without sedation.

    Pagliara, Camilla / Zambaiti, Elisa / Fati, Federica / Guanà, Riccardo / Scottoni, Federico / Gennari, Fabrizio / Gamba, Piergiorgio

    Minerva pediatrics

    2023  

    Abstract: Background: Non-operative radiological reduction (NORR) is usually the first line treatment in pediatric ileo-colic intussusception. The aim of our study was to compare outcomes of NORR with or without sedation.: Methods: All patients undergoing to ... ...

    Abstract Background: Non-operative radiological reduction (NORR) is usually the first line treatment in pediatric ileo-colic intussusception. The aim of our study was to compare outcomes of NORR with or without sedation.
    Methods: All patients undergoing to contrast enema NORR for intussusception between 01.01.2015 to 31.12.2020 in two hospitals were included: in one centre patients were sedated (A) while in the other patients were awake (B). Primary outcome was the rate of radiological reduction. Secondary outcomes were length-of-stay, complications and recurrence rate.
    Results: Seventy-seven and 49 patients were included in group A and B respectively. Successful reduction rate was 72.7% in group A and 61.2% in group B (P>0.05). There were no complications related to the procedure among the 2 groups. Adverse events to sedation were observed in 3 patients.
    Conclusions: NORR has similar success rate when performed under sedation or awake, despite the former being graved by additional anesthesiologic risks and thus warrant careful indications.
    Language English
    Publishing date 2023-06-19
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062664-X
    ISSN 2724-5780
    ISSN (online) 2724-5780
    DOI 10.23736/S2724-5276.23.07149-5
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  2. Article ; Online: Accuracy of point-of-care ultrasound in the diagnosis of acute appendicitis in a pediatric emergency department.

    Balbo, Stefano / Pini, Cecilia Maria / Raffaldi, Irene / Delmonaco, Angelo Giovanni / Castagno, Emanuele / Guanà, Riccardo / Di Rosa, Gianpaolo / Bondone, Claudia

    Journal of clinical ultrasound : JCU

    2024  

    Abstract: Purpose: To investigate the accuracy of point-of-care ultrasound (PoCUS) in diagnosing acute appendicitis in children; to evaluate the concordance between PoCUS performed by a pediatric emergency physician (PedEm) and ultrasonography (US) performed by a ...

    Abstract Purpose: To investigate the accuracy of point-of-care ultrasound (PoCUS) in diagnosing acute appendicitis in children; to evaluate the concordance between PoCUS performed by a pediatric emergency physician (PedEm) and ultrasonography (US) performed by a radiologist; to draw a "learning curve."
    Methods: We prospectively enrolled children aged 0-14 years old led to the Emergency Department of Regina Margherita Children's Hospital, from January 2021 to June 2021, with suspected acute appendicitis. PoCUS was performed by a single trained PedEm, blindly to the radiologist's scan. A "self-assessment score" and the "time of duration of PoCUS" were recorded for each patient. Final diagnosis of appendicitis was made by a pediatric surgeon.
    Results: We enrolled 62 children (2-14 years). Overall sensitivity of PoCUS was 88%, specificity 90%; PPV 90.6%, and NPV 86.6%. Global concordance between the PedEm and the radiologist was good/excellent (k 0.74). The mean duration of PoCUS significantly decreased during the study period, while the self-assessment score increased.
    Conclusion: This is a preliminary study that shows the effectiveness of PoCUS in diagnosing acute appendicitis; furthermore, it shows how the PedEm's performance may improve over time. The learning curve showed how the experience of the PedEm affects the accuracy of PoCUS.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189393-2
    ISSN 1097-0096 ; 0091-2751
    ISSN (online) 1097-0096
    ISSN 0091-2751
    DOI 10.1002/jcu.23658
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  3. Article: A case of vanishing gastroschisis with short bowel syndrome treated by total parenteral nutrition and intestinal lengthening procedures.

    Guanà, Riccardo / Marocco, Lucia / Garofalo, Salvatore / Zambaiti, Elisa / Pane, Alessandro / Scottoni, Federico / Fusaro, Fabio / Perucca, Giulia / Gennari, Fabrizio

    SAGE open medical case reports

    2023  Volume 11, Page(s) 2050313X231157490

    Abstract: The diagnosis of vanishing gastroschisis is made when in the presence of a full-thickness intrauterine abdominal wall defect the eviscerated loops are incarcerated in the fascial interruption. Four types of vanishing gastroschisis are described (A-D). We ...

    Abstract The diagnosis of vanishing gastroschisis is made when in the presence of a full-thickness intrauterine abdominal wall defect the eviscerated loops are incarcerated in the fascial interruption. Four types of vanishing gastroschisis are described (A-D). We report on the case of a newborn with a vanishing gastroschisis-D. Gastroschisis was diagnosed at the 19th week of gestation, confirmed at the 30th, when the herniated loops previously visible to the right of the funiculus were no longer visualized. At the 32nd week, delivery was induced. The neonate weighed 1600 g, and the abdomen was distended, free from skin defects. On surgical exploration, the jejunum was 13 cm in length, with a blind ending. The post-atretic intestine measured 22 cm. A jejunostomy and a colostomy were built. The child received total parenteral nutrition for 13 months due to short bowel syndrome and was then subjected to intestinal lengthening procedure when she was 18 months old. Vanishing gastroschisis is a rare entity with a worse prognosis of the "classic" gastroschisis.
    Language English
    Publishing date 2023-03-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X231157490
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  4. Article ; Online: An unusual case of acute postpartum bleeding in a mother and her newborn.

    Tessiatore, Patrizia / Guanà, Riccardo / Garofalo, Salvatore / Lemini, Riccardo / Marchese, Valentina / Pollio, Berardino / Gennari, Fabrizio

    Pediatrics and neonatology

    2020  Volume 61, Issue 4, Page(s) 455–456

    Language English
    Publishing date 2020-03-12
    Publishing country Singapore
    Document type Letter
    ZDB-ID 2441816-X
    ISSN 2212-1692 ; 1875-9572
    ISSN (online) 2212-1692
    ISSN 1875-9572
    DOI 10.1016/j.pedneo.2020.03.005
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  5. Article ; Online: A case of vanishing gastroschisis with short bowel syndrome treated by total parenteral nutrition and intestinal lengthening procedures

    Riccardo Guanà / Lucia Marocco / Salvatore Garofalo / Elisa Zambaiti / Alessandro Pane / Federico Scottoni / Fabio Fusaro / Giulia Perucca / Fabrizio Gennari

    SAGE Open Medical Case Reports, Vol

    2023  Volume 11

    Abstract: The diagnosis of vanishing gastroschisis is made when in the presence of a full-thickness intrauterine abdominal wall defect the eviscerated loops are incarcerated in the fascial interruption. Four types of vanishing gastroschisis are described (A–D). We ...

    Abstract The diagnosis of vanishing gastroschisis is made when in the presence of a full-thickness intrauterine abdominal wall defect the eviscerated loops are incarcerated in the fascial interruption. Four types of vanishing gastroschisis are described (A–D). We report on the case of a newborn with a vanishing gastroschisis-D. Gastroschisis was diagnosed at the 19th week of gestation, confirmed at the 30th, when the herniated loops previously visible to the right of the funiculus were no longer visualized. At the 32nd week, delivery was induced. The neonate weighed 1600 g, and the abdomen was distended, free from skin defects. On surgical exploration, the jejunum was 13 cm in length, with a blind ending. The post-atretic intestine measured 22 cm. A jejunostomy and a colostomy were built. The child received total parenteral nutrition for 13 months due to short bowel syndrome and was then subjected to intestinal lengthening procedure when she was 18 months old. Vanishing gastroschisis is a rare entity with a worse prognosis of the “classic” gastroschisis.
    Keywords Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Laparoscopic ovarian tissue collection for fertility preservation in children with malignancies: a multicentric experience.

    Perelli, Federica / Fusi, Giulia / Lonati, Luca / Gargano, Tommaso / Maffi, Michela / Avanzini, Stefano / Palo, Federico / Blanco Verdú, Maria Dolores / Del Cañizo López, Agustín / Garrido Colino, Carmen / Perucca, Giulia / Mattioli, Girolamo / Gennari, Fabrizio / Lima, Mario / Guanà, Riccardo

    Frontiers in surgery

    2024  Volume 11, Page(s) 1352698

    Abstract: Introduction: Long survivors after childhood cancer are increasing thanks to oncological improvements. Their quality of life and fertility-sparing should be considered in the early phases of each oncological pathway. Cryopreservation of ovarian tissue ... ...

    Abstract Introduction: Long survivors after childhood cancer are increasing thanks to oncological improvements. Their quality of life and fertility-sparing should be considered in the early phases of each oncological pathway. Cryopreservation of ovarian tissue removed before starting gonadotoxic therapies is the only fertility sparing procedure available for prepubertal children affected by cancer and it does not affect the timing of the start of the treatment.
    Materials and methods: The present study shows the surgical and clinical outcomes following laparoscopic ovarian tissue collection (LOTC) for a total of 311 patients aged between 0 and 17 years old from four different European Centers.
    Results: Only two major complications were reported according to the Clavien Dindo classification (0.6%).
    Discussion: LOTC can be considered a safe procedure.
    Language English
    Publishing date 2024-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2024.1352698
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  7. Article ; Online: Pediatric Wilkie's syndrome: Report of two monozygotic sisters managed conservatively.

    Guanà, Riccardo / Garofalo, Salvatore / Scottoni, Federico / Di Rosa, Gianpaolo / Gennari, Fabrizio

    Pediatrics and neonatology

    2020  Volume 62, Issue 2, Page(s) 227–228

    Language English
    Publishing date 2020-10-26
    Publishing country Singapore
    Document type Letter
    ZDB-ID 2441816-X
    ISSN 2212-1692 ; 1875-9572
    ISSN (online) 2212-1692
    ISSN 1875-9572
    DOI 10.1016/j.pedneo.2020.10.008
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  8. Article: Endobronchial Inflammatory Myofibroblastic Tumor in a 3-Year-Old Child.

    Guanà, Riccardo / Carpino, Andrea / Miglietta, Marta / Zambaiti, Elisa / Cerrina, Alessia / Lonati, Luca / Guerrera, Francesco / Vallero, Stefano / Garofalo, Salvatore / Bardessono, Marco / Maletta, Francesca / Shilly, Steffi / Gennari, Fabrizio

    European journal of pediatric surgery reports

    2023  Volume 11, Issue 1, Page(s) e5–e9

    Abstract: Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can occur at any age. However, it is primarily seen in children, with the most common site being in the lung parenchyma, usually present with rare endobronchial lesions. This case ... ...

    Abstract Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can occur at any age. However, it is primarily seen in children, with the most common site being in the lung parenchyma, usually present with rare endobronchial lesions. This case reports the incidence in a 3-year-old girl diagnosed with pericardiac pneumonia treated with antibiotics with no clinical improvement. A chest computed tomography (CT) scan identified a 1.5-cm lesion in the left main bronchus. Bronchoscopy revealed complete obstruction of the left main stem bronchus. A left posterolateral thoracotomy was performed. Additionally, a left sleeve upper bronchial resection was conducted under fibroendoscopic control. Definitive histology confirmed IMT. After 2 years of endoscopic follow-up, there is no evidence of recurrence.
    Language English
    Publishing date 2023-03-09
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2674016-3
    ISSN 2194-7627 ; 2194-7619
    ISSN (online) 2194-7627
    ISSN 2194-7619
    DOI 10.1055/s-0043-1764289
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  9. Article ; Online: Laparoendoscopic Management of Colonic Trichobezoar Causing Acute Large Bowel Obstruction in an Adolescent Girl.

    Guanà, Riccardo / Lonati, Luca / Cisarò, Fabio / Pizzol, Antonio / Garofalo, Salvatore / Scottoni, Federico / Pane, Alessandro / Marocco, Lucia / Gennari, Fabrizio

    JPGN reports

    2021  Volume 2, Issue 2, Page(s) e064

    Language English
    Publishing date 2021-04-12
    Publishing country United States
    Document type Case Reports
    ISSN 2691-171X
    ISSN (online) 2691-171X
    DOI 10.1097/PG9.0000000000000064
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  10. Article ; Online: Role of coagulation tests in the management of acute appendicitis in children.

    Guanà, Riccardo / Giuliano, Cristina / Pollio, Berardino / Perin, Silvia / Zambaiti, Elisa / Cerrina, Alessia / Pane, Alessandro / Scottoni, Federico / Lonati, Luca / Garofalo, Salvatore / Shilly, Steffi / Gennari, Fabrizio

    Minerva pediatrics

    2023  

    Abstract: Background: Acute appendicitis (AA) is one of the most common acute surgical conditions in children. Coagulation tests (CoTs) are usually utilized in preoperative assessment to rule out hemorrhagic risks. Our study aimed to evaluate the role of CoTs as ... ...

    Abstract Background: Acute appendicitis (AA) is one of the most common acute surgical conditions in children. Coagulation tests (CoTs) are usually utilized in preoperative assessment to rule out hemorrhagic risks. Our study aimed to evaluate the role of CoTs as predictors for the severity of AA.
    Methods: In a retrospective study, we compared the blood tests of two cohorts of pediatric patients with AA (group A and B) evaluated in the Emergency Department of a Pediatric Tertiary care hospital between January 2017 and January 2020. Children in Group A underwent appendectomies while those in Group B were treated with conservative management per hospital protocol. Group A was then subdivided into non-complicated (NCA) and complicated appendicitis (CA), and the CoTs were compared between the two subgroups.
    Results: Group A consisted of 198 patients and Group B of 150 patients. Blood tests, including CoTs and inflammatory markers, were compared between the 2 groups. We found a statistically significant difference in PT ratio mean value between Group A and B, suggesting that those who underwent appendicectomies had higher PT ratio values. From a pathophysiological point of view, we speculated that the variation of PT ratio in AA might be secondary to a vitamin K absorption deficit due to enteric inflammation.
    Conclusions: Our study underlined that a longer PT ratio could be helpful to distinguish CA from NCA. Further investigations may lead to the role of the PT ratio in the choice between conservative and surgical management.
    Language English
    Publishing date 2023-06-16
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062664-X
    ISSN 2724-5780
    ISSN (online) 2724-5780
    DOI 10.23736/S2724-5276.23.07200-2
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