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  1. Article ; Online: Ketoacidosis in a Toddler: A Case Report.

    Nathan, Suresh K / Sethuraman, Usha / Prout, Andrew

    Clinical pediatrics

    2024  , Page(s) 99228231223309

    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231223309
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluation and Management of Elevated BP in Children in the ED.

    Awad, Lilian / Sethuraman, Usha

    Current hypertension reports

    2023  Volume 26, Issue 3, Page(s) 99–105

    Abstract: Purpose of review: Pediatric hypertension has been on the rise over the past four decades. While most cases are evaluated and managed in the primary healthcare setting, some children may be referred to the emergency department (ED) for an expedited ... ...

    Abstract Purpose of review: Pediatric hypertension has been on the rise over the past four decades. While most cases are evaluated and managed in the primary healthcare setting, some children may be referred to the emergency department (ED) for an expedited workup of elevated blood pressure or for management of hypertensive crisis.
    Recent findings: Acute severe hypertension without end-organ damage and hypertensive emergency are life-threatening conditions that healthcare providers must be prepared to accurately recognize and treat as pediatric hypertension increases in prevalence. In this article, we review the most recent definitions of elevated blood pressure and hypertension and discuss the updated literature on the evaluation and management of hypertension and hypertensive crisis of children in the ED.
    MeSH term(s) Child ; Humans ; Hypertension/diagnosis ; Hypertension/drug therapy ; Blood Pressure/physiology ; Hypertensive Crisis ; Emergency Service, Hospital ; Prevalence
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057367-4
    ISSN 1534-3111 ; 1522-6417
    ISSN (online) 1534-3111
    ISSN 1522-6417
    DOI 10.1007/s11906-023-01283-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison of Paladai Cup Against Nifty Cup Feeding in Preterm Low-Birth-Weight Infants: An Open-Labeled Randomized Controlled Trial.

    Duruvasal, Priya Dharshini / Devi, Usha / Patil, Utkarsh / Sethuraman, Giridhar

    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

    2024  

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2234680-6
    ISSN 1556-8342 ; 1556-8253
    ISSN (online) 1556-8342
    ISSN 1556-8253
    DOI 10.1089/bfm.2023.0308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Aphallia in a neonate with VACTERL malformation: report of a rare association.

    Krishnamoorthy, Kiruthi / Sethuraman, Giridhar / Devi, Usha

    Clinical dysmorphology

    2023  Volume 32, Issue 2, Page(s) 74–76

    MeSH term(s) Infant, Newborn ; Humans ; Kidney ; Abnormalities, Multiple ; Heart Defects, Congenital ; Limb Deformities, Congenital ; Anal Canal ; Trachea ; Spine
    Language English
    Publishing date 2023-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1121482-x
    ISSN 1473-5717 ; 0962-8827
    ISSN (online) 1473-5717
    ISSN 0962-8827
    DOI 10.1097/MCD.0000000000000445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comparison of anaphylaxis epidemiology between urban and suburban pediatric emergency departments.

    Gurkha, Dhritiman / Podolsky, Robert / Sethuraman, Usha / Levasseur, Kelly

    BMC pediatrics

    2023  Volume 23, Issue 1, Page(s) 85

    Abstract: Background: Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. To date, there are no published data on epidemiology of pediatric anaphylaxis in Michigan. Our objective was to describe and compare the time trends in ... ...

    Abstract Background: Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. To date, there are no published data on epidemiology of pediatric anaphylaxis in Michigan. Our objective was to describe and compare the time trends in incidence of anaphylaxis in urban and suburban populations of Metro Detroit.
    Methods: We performed a retrospective study of Pediatric Emergency Department (ED) anaphylaxis visits from January 1, 2010, to December 1, 2017. The study was conducted at 1 suburban ED (SED) and 1 urban ED (UED). We identified cases using an International Classification of Diseases (ICD) 9 and 10 query of the electronic medical record. Patients were included if they aged 0-17 years and met the 2006 National Institute of Allergy and Infectious Disease and the Food Allergy and Anaphylaxis Network diagnostic criteria for anaphylaxis. The anaphylaxis rate was calculated as the number of detected cases divided by the total number of pediatric emergency room visits for that month. Anaphylaxis rates were compared between the two EDs using Poisson regression.
    Results: A total of 8,627 patient encounters had ICD codes for anaphylaxis, of which 703 visits fulfilled the inclusion criteria and were used in subsequent analyses. Overall, the incidence of anaphylaxis was more common in males and in children < 4 years of age in both centers. Although the total number of anaphylaxis related visits was higher at UED over the eight-year time frame for this study, the anaphylaxis rate (cases per 100,000 ED visits) throughout the study was higher at the SED. While the observed anaphylaxis rate at UED was 10.47 - 162.05 cases per 100,000 ED visits, the observed anaphylaxis rate at SED was 0 - 556.24 cases per 100,000 ED visits.
    Conclusion: Pediatric anaphylaxis rates differ significantly between urban and suburban populations in metro Detroit EDs. The rate of anaphylaxis related visits to the ED has significantly increased over the past 8 years in the metro Detroit area, with significantly higher rise in suburban compared to urban ED. More studies are needed to explore the reasons for this observed difference in increase rates.
    MeSH term(s) Male ; Child ; Humans ; Child, Preschool ; Anaphylaxis/epidemiology ; Anaphylaxis/etiology ; Anaphylaxis/diagnosis ; Retrospective Studies ; Food Hypersensitivity/complications ; Emergency Service, Hospital ; Incidence
    Language English
    Publishing date 2023-02-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-03898-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Infrahyoid Thyroglossal Duct Cyst Causing Airway Compromise in a Neonate: Surgical Management and Review of Literature.

    Mangalath, Sruthi / Devi, Usha / Sethuraman, Giridhar / Gurunathan, Moorthy

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2022  Volume 75, Issue 2, Page(s) 979–983

    Abstract: Thyroglossal duct cyst (TGDC) rarely becomes symptomatic in the neonatal period unlike other congenital neck swellings which present with high airway obstruction. An infrahyoid TGDC presenting with airway compromise in a neonate is even rarer. We hereby ... ...

    Abstract Thyroglossal duct cyst (TGDC) rarely becomes symptomatic in the neonatal period unlike other congenital neck swellings which present with high airway obstruction. An infrahyoid TGDC presenting with airway compromise in a neonate is even rarer. We hereby report a newborn with significant respiratory distress necessitating intubation and ventilation since birth. He had multiple extubation failures and signs of upper airway obstruction post-extubation. Computed tomography demonstrated a cystic lesion, probably an infrahyoid TGDC compressing the laryngeal lumen. The cyst was removed by Sistrunk procedure and histopathology confirmed the diagnosis. The child was discharged 5 days after surgery and was asymptomatic on follow-ups.
    Language English
    Publishing date 2022-11-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-022-03252-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Delayed cord clamping versus cord milking in vigorous neonates ≥35 weeks gestation born via cesarean: A Randomized clinical trial.

    Murali, Mithuna / Sethuraman, Giridhar / Vasudevan, Jaishree / Umadevi, L / Devi, Usha

    Journal of neonatal-perinatal medicine

    2023  Volume 16, Issue 4, Page(s) 597–603

    Abstract: Background: Delayed cord clamping (DCC) is the recommended strategy in neonates not requiring resuscitation, but umbilical cord milking (UCM) can also be used in term babies. DCC has been found to offer advantages more than just placental transfusion.!## ...

    Abstract Background: Delayed cord clamping (DCC) is the recommended strategy in neonates not requiring resuscitation, but umbilical cord milking (UCM) can also be used in term babies. DCC has been found to offer advantages more than just placental transfusion.
    Objective: To compare the neonatal outcomes of DCC and UCM at birth in vigorous neonates ≥35 weeks born via cesarean section.
    Methods: We included all vigorous neonates born ≥35 weeks of gestation through the cesarean section in this open-label randomized controlled trial. They were randomized into Group-A (DCC-cord was clamped 60 s after birth) or Group B(UCM). For neonates in Group B, the intact cord was milked at 25 cm from the stump 3 times towards the neonate and then clamped. The primary outcome was hematocrit at 72 h of life. Secondary outcomes were serum ferritin between 6 and 10 weeks of life, serum bilirubin at 72 h of life, need and duration of phototherapy, respiratory distress, hypoglycemia, hypotension, and sepsis.
    Results: Baseline characteristics were similar in both the groups. The mean hematocrit at 72 h was more in the DCC group compared to the UCM group [(55.60±4.50) vs (53.89±4.44), MD (95% CI) = 1.71 (0.26, 3.16); p = 0.021]. There was no significant difference in median serum ferritin between the groups [102.88(84.67-173.24) vs 137.93(85.15-230.40); p = 0.173]. There was no significant difference in clinical outcomes.
    Conclusion: In neonates born via cesarean section, DCC resulted in improved hematocrit levels by 72 hours compared to UCM. DCC results in better placental transfusion.
    MeSH term(s) Female ; Humans ; Infant ; Infant, Newborn ; Pregnancy ; Cesarean Section ; Constriction ; Ferritins ; Infant, Premature ; Placenta ; Time Factors ; Umbilical Cord ; Umbilical Cord Clamping
    Chemical Substances Ferritins (9007-73-2)
    Language English
    Publishing date 2023-11-25
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 2435387-5
    ISSN 1878-4429 ; 1934-5798
    ISSN (online) 1878-4429
    ISSN 1934-5798
    DOI 10.3233/NPM-230069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Association between respiratory rate oxygenation index and need for positive pressure ventilation in children on high flow nasal cannula for bronchiolitis.

    Kannikeswaran, Nirupama / Whittaker, Peter / Sethuraman, Usha

    European journal of pediatrics

    2022  Volume 181, Issue 11, Page(s) 3977–3983

    Abstract: Our objective was to evaluate the association of respiratory rate oxygenation index (ROX) with the need for positive pressure ventilation in children < 2 years of age with bronchiolitis on high flow nasal cannula (HFNC) therapy. We performed a single- ... ...

    Abstract Our objective was to evaluate the association of respiratory rate oxygenation index (ROX) with the need for positive pressure ventilation in children < 2 years of age with bronchiolitis on high flow nasal cannula (HFNC) therapy. We performed a single-center prospective observational study of a convenience sample of children < 2 years of age with bronchiolitis who had HFNC initiated in the pediatric emergency department between November and March, 2018-2020. ROX was calculated as pulse oximetry/FiO
    Conclusion: Low ROX index was associated with the need for PPV in children with bronchiolitis on HFNC. The risk stratification provided and ROX threshold for risk stratification require confirmation in other populations with a larger sample size.
    What is known: • Demographic and clinical factors associated with high flow nasal cannula (HFNC) therapy in children with bronchiolitis has been studied.
    What is new: • This is the first study to  report the utility of association of Respiratory Rate Oxygenation (ROX) index for need for positive pressure ventilation (PPV) in children  < 2 years of age with bronchiolitis on HFNC therapy. • ROX was lower in children who required PPV and children whose ROX was in the lowest quartile (< 5.39) were three times more likely to require PPV compared to those in the highest quartile (> 8.21).
    MeSH term(s) Bronchiolitis/therapy ; Cannula ; Child ; Continuous Positive Airway Pressure/methods ; Humans ; Noninvasive Ventilation ; Oxygen Inhalation Therapy/methods ; Respiratory Insufficiency ; Respiratory Rate
    Language English
    Publishing date 2022-09-14
    Publishing country Germany
    Document type Journal Article ; Observational Study
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-022-04607-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ralstonia mannitolilytica

    Rajendran, Usha Devi / Sundaramoorthy, Subha / Sethuraman, Giridhar

    Tropical doctor

    2021  Volume 52, Issue 1, Page(s) 216–217

    Abstract: Ralstonia ... ...

    Abstract Ralstonia mannitolilytica
    MeSH term(s) Cross Infection/diagnosis ; Cross Infection/drug therapy ; Cross Infection/epidemiology ; Gram-Negative Bacterial Infections/diagnosis ; Gram-Negative Bacterial Infections/drug therapy ; Gram-Negative Bacterial Infections/epidemiology ; Humans ; Infant, Newborn ; Intensive Care Units, Neonatal ; Ralstonia ; Sepsis/diagnosis ; Sepsis/drug therapy ; Sepsis/epidemiology
    Language English
    Publishing date 2021-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/00494755211036557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to Letter to the Editor by Kang-Auger G, et al.

    Kannikeswaran, Nirupama / Ehrman, Robert R / Vitale, Lisa / Oag, Katherine / Sundaralingam, Sureja / Spencer, Priya / Donoghue, Lydia / Sethuraman, Usha

    Journal of pediatric surgery

    2023  Volume 58, Issue 10, Page(s) 2063–2064

    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2023.06.002
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