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Article ; Online: Severe Agitation in a Teenager With Spastic Cerebral Palsy: A Clinical Challenge.

Greenky, David / Khan, Naghma S

2020 Volume 36, Issue 12, Page(s) e745–e746

Abstract: Neuroleptic malignant syndrome is a challenging diagnosis because it mimics many other conditions. We present a case of a 16-year-old boy with spastic cerebral palsy who presented with severe agitation, hyperthermia, and autonomic dysfunction. He arrived ...

Abstract	Neuroleptic malignant syndrome is a challenging diagnosis because it mimics many other conditions. We present a case of a 16-year-old boy with spastic cerebral palsy who presented with severe agitation, hyperthermia, and autonomic dysfunction. He arrived to a community pediatric hospital without a caregiver to provide a detailed history, which further complicated his management.
MeSH term(s)	Adolescent ; Cerebral Palsy ; Humans ; Male ; Neuroleptic Malignant Syndrome ; Psychomotor Agitation
Language	English
Publishing date	2020-05-29
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	632588-9
ISSN	1535-1815 ; 0749-5161
ISSN (online)	1535-1815
ISSN	0749-5161
DOI	10.1097/PEC.0000000000002118
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Article: A panel cointegration analysis of linkages between international trade and tourism: case of India and South Asian Association for Regional Cooperation (SAARC) countries.

Azmi, Shujaat Naeem / Khan, Tasneem / Azmi, Wajahat / Azhar, Naghma

Quality & quantity

2023 , Page(s) 1–20

Abstract: The study is undertaken to examine international trade and tourism nexus in case of India and SAARC countries. To achieve the objective, panel cointegration is employed over the period of 22 years (1997 to 2018). The results from both first and second ... ...

Abstract	The study is undertaken to examine international trade and tourism nexus in case of India and SAARC countries. To achieve the objective, panel cointegration is employed over the period of 22 years (1997 to 2018). The results from both first and second generation cointegration tests indicated the existence of long run equilibrium among tourism, export, and import. Albeit there are differences between short-term and long-term associations, the findings from autoregressive distributed lag approach indicates strong long-term linkages between trade and tourism. A possible channel of exports exerting a positive influence on tourist arrival is that the products in foreign markets increase the recognition and image of a country eventually leading to more tourists. Moreover, increased exports are expected to increase business trips further increasing the leisure trips and hence a strong linkage between export and tourism. On the other hand, a possible explanation of positive effect of imports on tourism could be that the destination countries which provide tourists with products according to their home taste encourage tourists to travel to these countries. The findings provided in the paper have strong implications for expanding India's tourism footprint in the region.
Language	English
Publishing date	2023-01-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2003280-8
ISSN	1573-7845 ; 0033-5177
ISSN (online)	1573-7845
ISSN	0033-5177
DOI	10.1007/s11135-022-01602-7
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Article ; Online: Tea Polyphenols in Promotion of Human Health.

Khan, Naghma / Mukhtar, Hasan

Nutrients

2018 Volume 11, Issue 1

Abstract: Tea is the most widely used beverage worldwide. Japanese and Chinese people have been drinking tea for centuries and in Asia, it is the most consumed beverage besides water. It is a rich source of pharmacologically active molecules which have been ... ...

Abstract	Tea is the most widely used beverage worldwide. Japanese and Chinese people have been drinking tea for centuries and in Asia, it is the most consumed beverage besides water. It is a rich source of pharmacologically active molecules which have been implicated to provide diverse health benefits. The three major forms of tea are green, black and oolong tea based on the degree of fermentation. The composition of tea differs with the species, season, leaves, climate, and horticultural practices. Polyphenols are the major active compounds present in teas. The catechins are the major polyphenolic compounds in green tea, which include epigallocatechin-3-gallate (EGCG), epigallocatechin, epicatechin-3-gallate and epicatechin, gallocatechins and gallocatechin gallate. EGCG is the predominant and most studied catechin in green tea. There are numerous evidences from cell culture and animal studies that tea polyphenols have beneficial effects against several pathological diseases including cancer, diabetes and cardiovascular diseases. The polyphenolic compounds present in black tea include theaflavins and thearubigins. In this review article, we will summarize recent studies documenting the role of tea polyphenols in the prevention of cancer, diabetes, cardiovascular and neurological diseases.
MeSH term(s)	Cardiovascular Diseases/prevention & control ; Central Nervous System Diseases/prevention & control ; Diabetes Mellitus/prevention & control ; Humans ; Neoplasms/prevention & control ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Tea/chemistry
Chemical Substances	Polyphenols ; Tea
Language	English
Publishing date	2018-12-25
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu11010039
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Article: Tea Polyphenols in Promotion of Human Health

Khan, Naghma / Mukhtar, Hasan

Nutrients. 2018 Dec. 25, v. 11, no. 1

2018

Abstract	Tea is the most widely used beverage worldwide. Japanese and Chinese people have been drinking tea for centuries and in Asia, it is the most consumed beverage besides water. It is a rich source of pharmacologically active molecules which have been implicated to provide diverse health benefits. The three major forms of tea are green, black and oolong tea based on the degree of fermentation. The composition of tea differs with the species, season, leaves, climate, and horticultural practices. Polyphenols are the major active compounds present in teas. The catechins are the major polyphenolic compounds in green tea, which include epigallocatechin-3-gallate (EGCG), epigallocatechin, epicatechin-3-gallate and epicatechin, gallocatechins and gallocatechin gallate. EGCG is the predominant and most studied catechin in green tea. There are numerous evidences from cell culture and animal studies that tea polyphenols have beneficial effects against several pathological diseases including cancer, diabetes and cardiovascular diseases. The polyphenolic compounds present in black tea include theaflavins and thearubigins. In this review article, we will summarize recent studies documenting the role of tea polyphenols in the prevention of cancer, diabetes, cardiovascular and neurological diseases.
Keywords	Chinese people ; active ingredients ; animal models ; black tea ; cardiovascular diseases ; catechin ; cell culture ; climate ; diabetes ; epicatechin ; epigallocatechin gallate ; fermentation ; green tea ; horticulture ; human health ; leaves ; medicinal properties ; neoplasms ; nervous system diseases ; oolong tea ; tea (beverage) ; theaflavins ; Asia
Language	English
Dates of publication	2018-1225
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu11010039
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Rational Ionothermal Copolymerization of TCNQ with PCN Semiconductor for Enhanced Photocatalytic Full Water Splitting.

Hayat, Asif / Shaishta, Naghma / Mane, Sunil Kumar Baburao / Khan, Javid / Hayat, Ashiq

ACS applied materials & interfaces

2019 Volume 11, Issue 50, Page(s) 46756–46766

Abstract: Photocatalytic full water splitting remains the perfect way to generate oxygen ( ... ...

Abstract	Photocatalytic full water splitting remains the perfect way to generate oxygen (O
Language	English
Publishing date	2019-12-06
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.9b15537
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Article ; Online: Molecular engineering of carbon nitride towards photocatalytic H

Hayat, Asif / Shaishta, Naghma / Uddin, Ikram / Khan, Muhammad / Mane, Sunil Kumar Baburao / Hayat, Ashiq / Ullah, Ikram / Ur Rehman, Ata / Ali, Tariq / Manjunatha, G

Journal of colloid and interface science

2021 Volume 597, Page(s) 39–47

Abstract: The development of superior heterogeneous catalyst for hydrogen ( ... ...

Abstract	The development of superior heterogeneous catalyst for hydrogen (H
Language	English
Publishing date	2021-03-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	241597-5
ISSN	1095-7103 ; 0021-9797
ISSN (online)	1095-7103
ISSN	0021-9797
DOI	10.1016/j.jcis.2021.03.159
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Article ; Online: Dietary agents for prevention and treatment of lung cancer.

Khan, Naghma / Mukhtar, Hasan

Cancer letters

2015 Volume 359, Issue 2, Page(s) 155–164

Abstract: Lung cancer is a prominent cause of cancer-associated mortality worldwide. The main reason for high mortality due to lung cancer is attributable to the fact that the diagnosis is generally made when it has spread beyond a curable stage and cannot be ... ...

Abstract	Lung cancer is a prominent cause of cancer-associated mortality worldwide. The main reason for high mortality due to lung cancer is attributable to the fact that the diagnosis is generally made when it has spread beyond a curable stage and cannot be treated surgically or with radiation therapy. Therefore, new approaches like dietary modifications could be extremely useful in reducing lung cancer incidences. Several fruits and vegetables offer a variety of bioactive compounds to afford protection against several diseases, including lung cancer. A number of research studies involving dietary agents provide strong evidence for their role in the prevention and treatment of lung cancer, and have identified their molecular mechanisms of action and potential targets. In this review article, we summarize data from in-vitro and in-vivo studies and where available, in clinical trials, on the effects of some of the most promising dietary agents against lung cancer.
MeSH term(s)	Adenocarcinoma/drug therapy ; Adenocarcinoma/prevention & control ; Administration, Oral ; Animals ; Anticarcinogenic Agents/administration & dosage ; Antineoplastic Agents, Phytogenic/administration & dosage ; Catechin/administration & dosage ; Catechin/analogs & derivatives ; Curcumin/administration & dosage ; Flavonoids/administration & dosage ; Humans ; Indoles/administration & dosage ; Isothiocyanates/administration & dosage ; Lung Neoplasms/drug therapy ; Lung Neoplasms/prevention & control ; Plant Extracts/administration & dosage ; Polyphenols/administration & dosage
Chemical Substances	Anticarcinogenic Agents ; Antineoplastic Agents, Phytogenic ; Flavonoids ; Indoles ; Isothiocyanates ; Plant Extracts ; Polyphenols ; Catechin (8R1V1STN48) ; epigallocatechin gallate (BQM438CTEL) ; indole-3-carbinol (C11E72455F) ; Curcumin (IT942ZTH98) ; fisetin (OO2ABO9578)
Language	English
Publishing date	2015-04-10
Publishing country	Ireland
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	195674-7
ISSN	1872-7980 ; 0304-3835
ISSN (online)	1872-7980
ISSN	0304-3835
DOI	10.1016/j.canlet.2015.01.038
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Article ; Online: Tea and health: studies in humans.

Khan, Naghma / Mukhtar, Hasan

Current pharmaceutical design

2013 Volume 19, Issue 34, Page(s) 6141–6147

Abstract: Tea, next to water is the cheapest beverage humans consume. Drinking the beverage tea has been considered a healthpromoting habit since ancient times. The modern medicinal research is providing a scientific basis for this belief. The evidence supporting ... ...

Abstract	Tea, next to water is the cheapest beverage humans consume. Drinking the beverage tea has been considered a healthpromoting habit since ancient times. The modern medicinal research is providing a scientific basis for this belief. The evidence supporting the health benefits of tea drinking grows stronger with each new study that is published in the scientific literature. Tea plant Camellia sinensis has been cultivated for thousands of years and its leaves have been used for medicinal purposes. Tea is used as a popular beverage worldwide and its ingredients are now finding medicinal benefits. Encouraging data showing cancer-preventive effects of green tea from cell-culture, animal and human studies have emerged. Evidence is accumulating that black tea may have similar beneficial effects. Tea consumption has also been shown to be useful for prevention of many debilitating human diseases that include maintenance of cardiovascular and metabolic health. Various studies suggest that polyphenolic compounds present in green and black tea are associated with beneficial effects in prevention of cardiovascular diseases, particularly of atherosclerosis and coronary heart disease. In addition, anti-aging, antidiabetic and many other health beneficial effects associated with tea consumption are described. Evidence is accumulating that catechins and theaflavins, which are the main polyphenolic compounds of green and black tea, respectively, are responsible for most of the physiological effects of tea. This article describes the evidences from clinical and epidemiological studies in the prevention of chronic diseases like cancer and cardiovascular diseases and general health promotion associated with tea consumption.
MeSH term(s)	Animals ; Biological Availability ; Camellia sinensis/chemistry ; Clinical Trials as Topic ; Humans ; Polyphenols/isolation & purification ; Polyphenols/pharmacokinetics ; Polyphenols/pharmacology ; Polyphenols/therapeutic use ; Tea
Chemical Substances	Polyphenols ; Tea
Language	English
Publishing date	2013-02-28
Publishing country	United Arab Emirates
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	1304236-1
ISSN	1873-4286 ; 1381-6128
ISSN (online)	1873-4286
ISSN	1381-6128
DOI	10.2174/1381612811319340008
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Article: Rational Ionothermal Copolymerization of TCNQ with PCN Semiconductor for Enhanced Photocatalytic Full Water Splitting

Hayat, Asif / Shaishta, Naghma / Mane, Sunil Kumar Baburao / Khan, Javid / Hayat, Ashiq

ACS applied materials & interfaces. 2019 Nov. 25, v. 11, no. 50

2019

Abstract: Photocatalytic full water splitting remains the perfect way to generate oxygen (O2) and hydrogen (H2) gases driven by sunlight to address the future environmental issues as well as energy demands. Owing to its exceptional properties, polymeric carbon ... ...

Abstract	Photocatalytic full water splitting remains the perfect way to generate oxygen (O2) and hydrogen (H2) gases driven by sunlight to address the future environmental issues as well as energy demands. Owing to its exceptional properties, polymeric carbon nitride (PCN) has been one of the most widely investigated semiconductor photocatalysts. Nevertheless, blank PCN characteristically displays restrained photocatalytic performance due to high-density defects in its framework that may perhaps perform the part of the recombination midpoint for photoproduced electron–hole pairs. Therefore, to overcome this problem, a simple approach to introduce 7,7,8,8-tetracyanoquinodimethane (TCNQ) with an electron-withdrawing characteristic modifier into the pristine PCN framework by the ionothermal method to enhance its optical, conductive, and photocatalytic properties has been undertaken. Results show that such integration of TCNQ results in the delocalization of the π-conjugated structure; significant changes in its chemical electronic configuration, band gap, and surface area; and enhanced production of electrons under visible light. As a result of this facile integration, our best sample (CNU-TCNQ9.0) produced a hydrogen evolution rate (HER) of 164.6 μmol h–1 for H2 and an oxygen evolution rate (OER) of 14.8 μmol h–1 for O2, which were found to be 2.4- and 2.6-fold greater than those produced with pure carbon nitride (CNU) sample, respectively. Hence, this work provides a reasonable alternative method to synthesize and design novel CNU-TCNQ backbone photocatalyst for organic photosynthesis, CO2 reduction, hydrogen evolution, etc.
Keywords	carbon dioxide ; carbon nitride ; copolymerization ; electrons ; energy ; gases ; hydrogen ; hydrogen production ; light ; oxygen ; oxygen production ; photocatalysis ; photocatalysts ; photosynthesis ; polymers ; semiconductors ; solar radiation ; surface area
Language	English
Dates of publication	2019-1125
Size	p. 46756-46766.
Publishing place	American Chemical Society
Document type	Article
ISSN	1944-8252
DOI	10.1021/acsami.9b15537
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Improving Discharge Instructions in a Pediatric Emergency Department: Impact of a Quality Initiative.

Akinsola, Bolanle / Cheng, John / Zmitrovich, April / Khan, Naghma / Jain, Shabnam

Pediatric emergency care

2017 Volume 33, Issue 1, Page(s) 10–13

Abstract: Background: Effective communication between physician and patient is essential to optimize care after discharge from the emergency department (ED). Written discharge care instructions (DCI) complement verbal instructions and have been shown to improve ... ...

Abstract	Background: Effective communication between physician and patient is essential to optimize care after discharge from the emergency department (ED). Written discharge care instructions (DCI) complement verbal instructions and have been shown to improve communication and patient management. In 2012, Centers for Medicare and Medicaid Services proposed a quality measure (OP-19) that assesses compliance with key elements considered essential for high-quality written DCI. Objective: To evaluate the impact of a QI intervention on improving quality of written DCI in a pediatric emergency department (PED). Methods: A QI initiative was conducted at a tertiary PED with greater than 60,000 annual visits. Based on Centers for Medicare and Medicaid Services OP-19 measure and group consensus, 8 elements were defined a priori as requisites for good quality DCI. These elements are:Providers reviewed a random sample of DCI of patients. Proportion of DCI that had each element documented was compared between preintervention phase (PRE) and postintervention phase (POST). Results: Three hundred twenty-nine DCI (PRE) and 1434 DCI (POST) were reviewed. The POST DCI showed statistically significant improvement for each of the 8 elements. The bundle measure (proportion containing all 8 elements) increased from 23% (PRE) to 79% (POST) (P < 0.001). Conclusions: The ED DCI improved in all 8 elements after a QI intervention. A detailed DCI at ED discharge enhances the patient's ability to comply with postdischarge treatment plan. Further studies are needed to evaluate the impact of improving DCI on ED return rates and other outcomes.
MeSH term(s)	Child ; Documentation/standards ; Emergency Service, Hospital/standards ; Female ; Health Services Research ; Humans ; Male ; Patient Discharge/standards ; Quality Improvement ; United States
Language	English
Publishing date	2017-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	632588-9
ISSN	1535-1815 ; 0749-5161
ISSN (online)	1535-1815
ISSN	0749-5161
DOI	10.1097/PEC.0000000000000816
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