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  1. Article: Multitask learning and nonlinear optimal control of the COVID-19 outbreak: A geometric programming approach.

    Hayhoe, Mikhail / Barreras, Francisco / Preciado, Victor M

    Annual reviews in control

    2021  Volume 52, Page(s) 495–507

    Abstract: We propose a multitask learning approach to learn the parameters of a compartmental discrete-time epidemic model from various data sources and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and ... ...

    Abstract We propose a multitask learning approach to learn the parameters of a compartmental discrete-time epidemic model from various data sources and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with implementing non-pharmaceutical interventions. We develop an extension of the SEIR epidemic model that captures the effects of changes in human mobility on the spread of the disease. The parameters of the model are learned using a multitask learning approach that leverages both data on the number of deaths across a set of regions, and cellphone data on individuals' mobility patterns specific to each region. Using this model, we propose a nonlinear optimal control problem aiming to find the optimal mobility-based intervention strategy that curbs the spread of the epidemic while obeying a budget on the economic cost incurred. We also show that the solution to this nonlinear optimal control problem can be efficiently found, in polynomial time, using tools from geometric programming. Furthermore, in the absence of a straightforward mapping from human mobility data to economic costs, we propose a practical method by which a budget on economic losses incurred may be chosen to eliminate excess deaths due to over-utilization of hospital resources. Our results are demonstrated with numerical simulations using real data from the COVID-19 pandemic in the Philadelphia metropolitan area.
    Language English
    Publishing date 2021-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501302-9
    ISSN 1872-9088 ; 1367-5788
    ISSN (online) 1872-9088
    ISSN 1367-5788
    DOI 10.1016/j.arcontrol.2021.04.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Stable and Transferable Hyper-Graph Neural Networks

    Hayhoe, Mikhail / Riess, Hans / Preciado, Victor M. / Ribeiro, Alejandro

    2022  

    Abstract: We introduce an architecture for processing signals supported on hypergraphs via graph neural networks (GNNs), which we call a Hyper-graph Expansion Neural Network (HENN), and provide the first bounds on the stability and transferability error of a ... ...

    Abstract We introduce an architecture for processing signals supported on hypergraphs via graph neural networks (GNNs), which we call a Hyper-graph Expansion Neural Network (HENN), and provide the first bounds on the stability and transferability error of a hypergraph signal processing model. To do so, we provide a framework for bounding the stability and transferability error of GNNs across arbitrary graphs via spectral similarity. By bounding the difference between two graph shift operators (GSOs) in the positive semi-definite sense via their eigenvalue spectrum, we show that this error depends only on the properties of the GNN and the magnitude of spectral similarity of the GSOs. Moreover, we show that existing transferability results that assume the graphs are small perturbations of one another, or that the graphs are random and drawn from the same distribution or sampled from the same graphon can be recovered using our approach. Thus, both GNNs and our HENNs (trained using normalized Laplacians as graph shift operators) will be increasingly stable and transferable as the graphs become larger. Experimental results illustrate the importance of considering multiple graph representations in HENN, and show its superior performance when transferability is desired.

    Comment: 13 pages, 1 figure
    Keywords Computer Science - Machine Learning
    Subject code 511
    Publishing date 2022-11-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Data-Driven Control of the COVID-19 Outbreak via Non-Pharmaceutical Interventions: A Geometric Programming Approach

    Hayhoe, Mikhail / Barreras, Francisco / Preciado, Victor M.

    Abstract: In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with implementing non- ... ...

    Abstract In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with implementing non-pharmaceutical interventions. We develop an extension of the SEIR epidemic model that captures the effects of changes in human mobility on the spread of the disease. The parameters of our data-driven model are learned using a multitask learning approach that leverages both data on the number of deaths across a set of regions, and cellphone data on individuals' mobility patterns specific to each region. We propose an optimal control problem on this data-driven model with a tractable solution provided by geometric programming. The result of this framework is a mobility-based intervention strategy that curbs the spread of the epidemic while obeying a budget on the economic cost incurred. Furthermore, in the absence of a straightforward mapping from human mobility data to economic costs, we propose a practical method by which a budget on economic losses incurred may be chosen to eliminate excess deaths due to over-utilization of hospital resources. Our results are demonstrated with numerical simulations using real data from the Philadelphia metropolitan area.
    Keywords covid19
    Publisher ArXiv
    Document type Article
    Database COVID19

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  4. Book ; Online: A Dynamical Approach to Efficient Eigenvalue Estimation in General Multiagent Networks

    Hayhoe, Mikhail / Barreras, Francisco / Preciado, Victor M.

    2020  

    Abstract: We propose a method to efficiently estimate the eigenvalues of any arbitrary (potentially weighted and/or directed) network of interacting dynamical agents from dynamical observations. These observations are discrete, temporal measurements about the ... ...

    Abstract We propose a method to efficiently estimate the eigenvalues of any arbitrary (potentially weighted and/or directed) network of interacting dynamical agents from dynamical observations. These observations are discrete, temporal measurements about the evolution of the outputs of a subset of agents (potentially one) during a finite time horizon; notably, we do not require knowledge of which agents are contributing to our measurements. We propose an efficient algorithm to exactly recover the (potentially complex) eigenvalues corresponding to network modes that are observable from the output measurements. The length of the sequence of measurements required by our method to generate a full reconstruction of the observable eigenvalue spectrum is, at most, twice the number of agents in the network, but smaller in practice. The proposed technique can be applied to networks of multiagent systems with arbitrary dynamics in both continuous- and discrete-time. Finally, we illustrate our results with numerical simulations.

    Comment: 12 pages, 3 figures. arXiv admin note: text overlap with arXiv:1912.03177
    Keywords Mathematics - Optimization and Control ; Computer Science - Multiagent Systems ; Electrical Engineering and Systems Science - Systems and Control ; Mathematics - Dynamical Systems ; Mathematics - Spectral Theory
    Subject code 006
    Publishing date 2020-07-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Online: Data-Driven Control of the COVID-19 Outbreak via Non-Pharmaceutical Interventions

    Hayhoe, Mikhail / Barreras, Francisco / Preciado, Victor M.

    A Geometric Programming Approach

    2020  

    Abstract: In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with implementing non- ... ...

    Abstract In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with implementing non-pharmaceutical interventions. We develop an extension of the SEIR epidemic model that captures the effects of changes in human mobility on the spread of the disease. The parameters of our data-driven model are learned using a multitask learning approach that leverages both data on the number of deaths across a set of regions, and cellphone data on individuals' mobility patterns specific to each region. We propose an optimal control problem on this data-driven model with a tractable solution provided by geometric programming. The result of this framework is a mobility-based intervention strategy that curbs the spread of the epidemic while obeying a budget on the economic cost incurred. Furthermore, in the absence of a straightforward mapping from human mobility data to economic costs, we propose a practical method by which a budget on economic losses incurred may be chosen to eliminate excess deaths due to over-utilization of hospital resources. Our results are demonstrated with numerical simulations using real data from the Philadelphia metropolitan area.

    Comment: 16 pages, 5 figures
    Keywords Mathematics - Optimization and Control ; Electrical Engineering and Systems Science - Systems and Control
    Subject code 330
    Publishing date 2020-11-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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