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Article ; Online: Comparing Hypothermic and Thermal Neutral Conditions to Induce Metabolic Suppression.

Rittenberger, Jon C / Clemency, Brian M / Monaco, Brian / Schwob, Jacqueline / Murphey, Joshua T / Hostler, David

Therapeutic hypothermia and temperature management

2024

Abstract: Suppressing metabolism in astronauts could decrease ... ...

Abstract	Suppressing metabolism in astronauts could decrease CO
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2609342-X
ISSN	2153-7933 ; 2153-7658
ISSN (online)	2153-7933
ISSN	2153-7658
DOI	10.1089/ther.2023.0085
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: "We're kind of on the back burner"

Lewinson, Terri D / Washington, Tiffany R / Allen, Sophia E / Murphey, James M / Onsando, W Moraa

Social work in health care

2023 Volume 62, Issue 6-7, Page(s) 243–262

Abstract: Medical social workers are essential members of healthcare teams, especially during a pandemic. Their scope of practice includes conducting psychological assessments, coordinating social services, connecting patients to resources that address social ... ...

Abstract	Medical social workers are essential members of healthcare teams, especially during a pandemic. Their scope of practice includes conducting psychological assessments, coordinating social services, connecting patients to resources that address social determinants of health, discharge planning, and patient advocacy. Social workers' experiences of psychological distress were unique even before the COVID-19 pandemic; their work demands a high amount of emotional investment as they frequently witness others' pain and suffering and navigate various daily challenges and crises. This study explores psychological distress experienced by medical social workers and the coping strategies used by these professionals during the pandemic prior to the COVID-19 vaccine rollout. Faced with conflicting information from state and federal agencies, social workers dealt with resource shortages, took on additional roles and responsibilities, and contended with regular value conflicts and ethical dilemmas. Our findings indicate that medical social workers are not sufficiently protected or prioritized in their workplaces and that infrastructure to support social workers' emotional wellbeing is lacking. Distinct themes that emerged from the data under the umbrella of psychological distress include feeling unprotected, overburdened, and undervalued. We discuss a need for targeted policy and sustainability-oriented solutions to improve coping and resilience, mitigate psychological distress, and prevent burnout among medical social workers.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics ; Social Workers ; COVID-19 Vaccines ; Adaptation, Psychological ; Psychological Distress ; Health Personnel/psychology
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-06-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	197616-3
ISSN	1541-034X ; 0098-1389
ISSN (online)	1541-034X
ISSN	0098-1389
DOI	10.1080/00981389.2023.2221718
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Book: Visual guide to musculoskeletal tumors

Wodajo, Felasfa M. / Gannon, Francis H. / Murphey, Mark D.

a clinical, radiologic, histologic approach

2010

Author's details	Felasfa M. Wodajo ; Francis H. Gannon ; Mark D. Murphey
Keywords	Bone Neoplasms / diagnosis ; Bone Neoplasms / pathology ; Soft Tissue Neoplasms / pathology ; Soft Tissue Neoplasms / diagnosis
Language	English
Size	XI, 226 S. : überw. Ill., 28 cm
Publisher	Saunders Elsevier
Publishing place	Philadelphia, Pa
Publishing country	United States
Document type	Book
Accompanying material	Zugang zur Internetausgabe über Code
HBZ-ID	HT016443489
ISBN	978-1-4377-0303-0 ; 1-4377-0303-8
Database	Catalogue ZB MED Medicine, Health

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2010 A 3665	order for loan	Magazin
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Article ; Online: Elliptical and spherical heads show similar obligate glenohumeral translation during axial rotation in total shoulder arthroplasty.

Muench, Lukas N / Murphey, Matthew / Oei, Bridget / Kia, Cameron / Obopilwe, Elifho / Cote, Mark P / Mazzocca, Augustus D / Berthold, Daniel P

BMC musculoskeletal disorders

2023 Volume 24, Issue 1, Page(s) 171

Abstract: Background: Elliptical shape humeral head prostheses have been recently proposed to reflect a more anatomic shoulder replacement. However, its effect on obligate glenohumeral translation during axial rotation compared to a standard spherical head is ... ...

Abstract	Background: Elliptical shape humeral head prostheses have been recently proposed to reflect a more anatomic shoulder replacement. However, its effect on obligate glenohumeral translation during axial rotation compared to a standard spherical head is still not well understood. The purpose of the study was to compare obligate humeral translation during axial rotation using spherical and elliptical shaped humeral head prostheses. It was hypothesized that the spherical head design would show significantly more obligate translation when compared to the elliptical design. Methods: Six fresh-frozen cadaveric shoulders were utilized for biomechanical testing of internal (IR) and external (ER) rotation at various levels of abduction (0°, 30°, 45°, 60°) with lines of pull along each of the rotator cuff muscles. Each specimen underwent the following three conditions: (1) native; total shoulder arthroplasty (TSA) using (2) an elliptical and (3) spherical humeral head implant. Obligate translation during IR and ER was quantified using a 3-dimensional digitizer. The radius of curvature of the superoinferior and anteroposterior dimensions of the implants was calculated across each condition. Results: Posterior and inferior translation as well as compound motion of spherical and elliptical heads during ER was similar at all abduction angles (P > 0.05, respectively). Compared to the native humeral head, both implants demonstrated significantly decreased posterior translation at 45° (elliptical: P = 0.003; spherical: P = 0.004) and 60° of abduction (elliptical: P < 0.001; spherical: P < 0.001). During internal rotation at 0° abduction, the spherical head showed significantly more compound motion (P = 0.042) compared to the elliptical head. The spherical implant also demonstrated increased anterior translation and compound motion during internal rotation at 60° abduction (P < 0.001) compared to the resting state. This difference was not significant for the native or elliptical head design at this angle (P > 0.05). Conclusion: In the setting of TSA, elliptical and spherical head implants showed similar obligate translation and overall compound motion during axial rotation. A gained understanding of the consequences of implant head shape in TSA may guide future surgical implant choice for better recreation of native shoulder kinematics and potentially improved patient outcomes. Level of evidence: Controlled Laboratory Study.
MeSH term(s)	Humans ; Arthroplasty, Replacement, Shoulder ; Rotation ; Upper Extremity ; Arthroplasty, Replacement ; Bursitis ; Humeral Head/surgery
Language	English
Publishing date	2023-03-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2041355-5
ISSN	1471-2474 ; 1471-2474
ISSN (online)	1471-2474
ISSN	1471-2474
DOI	10.1186/s12891-023-06273-5
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Book ; Online: Automated Gait Generation For Walking, Soft Robotic Quadrupeds

Ketchum, Jake / Schiffer, Sophia / Sun, Muchen / Kaarthik, Pranav / Truby, Ryan L. / Murphey, Todd D.

2023

Abstract: Gait generation for soft robots is challenging due to the nonlinear dynamics and high dimensional input spaces of soft actuators. Limitations in soft robotic control and perception force researchers to hand-craft open loop controllers for gait sequences, ...

Abstract	Gait generation for soft robots is challenging due to the nonlinear dynamics and high dimensional input spaces of soft actuators. Limitations in soft robotic control and perception force researchers to hand-craft open loop controllers for gait sequences, which is a non-trivial process. Moreover, short soft actuator lifespans and natural variations in actuator behavior limit machine learning techniques to settings that can be learned on the same time scales as robot deployment. Lastly, simulation is not always possible, due to heterogeneity and nonlinearity in soft robotic materials and their dynamics change due to wear. We present a sample-efficient, simulation free, method for self-generating soft robot gaits, using very minimal computation. This technique is demonstrated on a motorized soft robotic quadruped that walks using four legs constructed from 16 "handed shearing auxetic" (HSA) actuators. To manage the dimension of the search space, gaits are composed of two sequential sets of leg motions selected from 7 possible primitives. Pairs of primitives are executed on one leg at a time; we then select the best-performing pair to execute while moving on to subsequent legs. This method -- which uses no simulation, sophisticated computation, or user input -- consistently generates good translation and rotation gaits in as low as 4 minutes of hardware experimentation, outperforming hand-crafted gaits. This is the first demonstration of completely autonomous gait generation in a soft robot. Comment: 7 Pages, 6 Figures, Published at IROS 2023
Keywords	Computer Science - Robotics ; Computer Science - Machine Learning
Subject code	629
Publishing date	2023-09-30
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Colloidal robotics.

Liu, Albert Tianxiang / Hempel, Marek / Yang, Jing Fan / Brooks, Allan M / Pervan, Ana / Koman, Volodymyr B / Zhang, Ge / Kozawa, Daichi / Yang, Sungyun / Goldman, Daniel I / Miskin, Marc Z / Richa, Andréa W / Randall, Dana / Murphey, Todd D / Palacios, Tomás / Strano, Michael S

Nature materials

2023 Volume 22, Issue 12, Page(s) 1453–1462

Abstract: Robots have components that work together to accomplish a task. Colloids are particles, usually less than 100 µm, that are small enough that they do not settle out of solution. Colloidal robots are particles capable of functions such as sensing, ... ...

Abstract	Robots have components that work together to accomplish a task. Colloids are particles, usually less than 100 µm, that are small enough that they do not settle out of solution. Colloidal robots are particles capable of functions such as sensing, computation, communication, locomotion and energy management that are all controlled by the particle itself. Their design and synthesis is an emerging area of interdisciplinary research drawing from materials science, colloid science, self-assembly, robophysics and control theory. Many colloidal robot systems approach synthetic versions of biological cells in autonomy and may find ultimate utility in bringing these specialized functions to previously inaccessible locations. This Perspective examines the emerging literature and highlights certain design principles and strategies towards the realization of colloidal robots.
Language	English
Publishing date	2023-08-24
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2088679-2
ISSN	1476-4660 ; 1476-1122
ISSN (online)	1476-4660
ISSN	1476-1122
DOI	10.1038/s41563-023-01589-y
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Article ; Online: Exploring relationships among multi-disciplinary assessments for knee joint health in service members with traumatic unilateral lower limb loss: a two-year longitudinal investigation.

Wasser, Joseph G / Hendershot, Brad D / Acasio, Julian C / Dodd, Lauren D / Krupenevich, Rebecca L / Pruziner, Alison L / Miller, Ross H / Goldman, Stephen M / Valerio, Michael S / Senchak, Lien T / Murphey, Mark D / Heltzel, David A / Fazio, Michael G / Dearth, Christopher L / Hager, Nelson A

Scientific reports

2023 Volume 13, Issue 1, Page(s) 21177

Abstract: Motivated by the complex and multifactorial etiologies of osteoarthritis, here we use a comprehensive approach evaluating knee joint health after unilateral lower limb loss. Thirty-eight male Service members with traumatic, unilateral lower limb loss ( ... ...

Abstract	Motivated by the complex and multifactorial etiologies of osteoarthritis, here we use a comprehensive approach evaluating knee joint health after unilateral lower limb loss. Thirty-eight male Service members with traumatic, unilateral lower limb loss (mean age = 38 yr) participated in a prospective, two-year longitudinal study comprehensively evaluating contralateral knee joint health (i.e., clinical imaging, gait biomechanics, physiological biomarkers, and patient-reported outcomes); seventeen subsequently returned for a two-year follow-up visit. For this subset with baseline and follow-up data, outcomes were compared between timepoints, and associations evaluated between values at baseline with two-year changes in tri-compartmental joint space. Upon follow-up, knee joint health worsened, particularly among seven Service members who presented at baseline with no joint degeneration (KL = 0) but returned with evidence of degeneration (KL ≥ 1). Joint space narrowing was associated with greater patellar tilt (r[12] = 0.71, p = 0.01), external knee adduction moment (r[13] = 0.64, p = 0.02), knee adduction moment impulse (r[13] = 0.61, p = 0.03), and CTX-1 concentration (r[11] = 0.83, p = 0.001), as well as lesser KOOS
MeSH term(s)	Male ; Humans ; Adult ; Longitudinal Studies ; Prospective Studies ; Knee Joint/diagnostic imaging ; Gait/physiology ; Osteoarthritis, Knee/diagnostic imaging ; Osteoarthritis, Knee/etiology ; Lower Extremity ; Biomechanical Phenomena
Language	English
Publishing date	2023-12-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-48662-9
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Article ; Online: Ultrasonography of Superficial Soft-Tissue Masses: Society of Radiologists in Ultrasound Consensus Conference Statement.

Jacobson, Jon A / Middleton, William D / Allison, Sandra J / Dahiya, Nirvikar / Lee, Kenneth S / Levine, Benjamin D / Lucas, David R / Murphey, Mark D / Nazarian, Levon N / Siegel, Geoffrey W / Wagner, Jason M

Radiology

2022 Volume 304, Issue 1, Page(s) 18–30

Abstract: The Society of Radiologists in Ultrasound convened a panel of specialists from radiology, orthopedic surgery, and pathology to arrive at a consensus regarding the management of superficial soft-tissue masses imaged with US. The recommendations in this ... ...

Abstract	The Society of Radiologists in Ultrasound convened a panel of specialists from radiology, orthopedic surgery, and pathology to arrive at a consensus regarding the management of superficial soft-tissue masses imaged with US. The recommendations in this statement are based on analysis of current literature and common practice strategies. This statement reviews and illustrates the US features of common superficial soft-tissue lesions that may manifest as a soft-tissue mass and suggests guidelines for subsequent management.
MeSH term(s)	Humans ; Radiologists ; Radiology ; Ultrasonography/methods
Language	English
Publishing date	2022-04-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.211101
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Article ; Online: Imaging of spindle cell lipoma.

Jelinek, J S / Wu, A / Wallace, M / Kumar, D / Henshaw, R M / Murphey, M J / Van Horn, A / Aboulafia, A J

Clinical radiology

2020 Volume 75, Issue 5, Page(s) 396.e15–396.e21

Abstract: ... with an average age of 56.5 years. Men were affected twice as frequently as women (M=18, F=9). SCLs ranged in size ...

Abstract	Aim: To review the evaluation, diagnosis, and treatment of spindle cell lipoma (SCL) with emphasis on the location of these tumours and the spectrum of magnetic resonance imaging (MRI) and computed tomography (CT) appearances. Materials and methods: The MRI and CT findings of 27 histopathologically proven SCLs were evaluated retrospectively. Imaging features evaluated included margins, percentage visible fat, MRI signal characteristics, oedema, and contrast enhancement patterns. Results: Patient ages ranged from 18 to 80 years with an average age of 56.5 years. Men were affected twice as frequently as women (M=18, F=9). SCLs ranged in size from 2 to 10 cm, with an average greatest dimension of 5.5 cm. Five lesions (19%) contained no visible fat on CT or MRI, and the leading differential diagnosis of high-grade soft-tissue sarcoma diagnosis was suggested by referring surgeons. Five lesions (19%) had <50% fatty areas, nine lesions (52%) demonstrated >50% but <90% fat at MRI or CT. Only three of 25 lesions (12%) had an appearance of a typical lipoma on unenhanced MRI sequences. All SCLs that were imaged with contrast medium (n = 18) demonstrated some degree of enhancement, with eight (44%) showing marked enhancement, four (22%) showing moderate, and six (33%) minimal enhancement. Conclusion: SCLs have considerably variable imaging appearances and may have minimal or no visible fat at MRI or CT. Imaging features may make it difficult to distinguish this benign tumour from a potentially higher-grade malignant tumour.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Contrast Media ; Female ; Humans ; Lipoma/diagnostic imaging ; Lipoma/pathology ; Lipoma/therapy ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Tomography, X-Ray Computed/methods
Chemical Substances	Contrast Media
Language	English
Publishing date	2020-01-10
Publishing country	England
Document type	Journal Article
ZDB-ID	391227-9
ISSN	1365-229X ; 0009-9260
ISSN (online)	1365-229X
ISSN	0009-9260
DOI	10.1016/j.crad.2019.11.020
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Article ; Online: Effect of donor

Kozlitina, Julia / Cohen, Naomi M / Sturtevant, Drew / Cohen, Jonathan C / Murphey-Half, Cathi / Saltarrelli, Jerome G / Jindra, Peter / Askar, Medhat / Hwang, Christine S / Vagefi, Parsia A / Lacelle, Chantale / Hobbs, Helen H / MacConmara, Malcolm P

EClinicalMedicine

2023 Volume 67, Page(s) 102350

Abstract: Background: Several genetic variants are associated with chronic liver disease. The role of these variants in outcomes after liver transplantation (LT) is uncertain. The aim of this study was to determine if donor genotype at risk-associated variants in ...

Abstract	Background: Several genetic variants are associated with chronic liver disease. The role of these variants in outcomes after liver transplantation (LT) is uncertain. The aim of this study was to determine if donor genotype at risk-associated variants in Methods: In this retrospective cohort study, data on 2346 adults who underwent first-time LT between January 1, 1999 and June 30, 2020 and who had donor DNA samples available at five large Transplant Immunology Laboratories in Texas, USA, were obtained from the United Network for Organ Sharing (UNOS). Duplicates, patients with insufficient donor DNA for genotyping, those who were <18 years of age at the time of transplant, had had a previous transplant or had missing genotype data were excluded. The primary outcomes were patient and graft survival after LT. The association between donor genotype and post-LT survival was examined using Kaplan-Meier method and multivariable-adjusted Cox proportional hazards models. Findings: Median age of LT recipients was 57 [interquartile range (IQR), 50-62] years; 837 (35.7%) were women; 1362 (58.1%) White, 713 (30.4%) Hispanic, 182 (7.8%) Black/African-American. Median follow-up time was 3.95 years. Post-LT survival was not affected by donor Interpretation: Donor Funding: The National Institutes of Health and American Society of Transplant Surgeons Collaborative Scientist Grant.
Language	English
Publishing date	2023-12-13
Publishing country	England
Document type	Journal Article
ISSN	2589-5370
ISSN (online)	2589-5370
DOI	10.1016/j.eclinm.2023.102350
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