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  1. Article: Susceptibility of maize genotypes to Rhyzopertha dominica (F.)

    Locatelli, D. P. / Castorina, G. / Sangiorgio, S. / Consonni, G. / Limonta, L.

    Journal of plant diseases and protection

    2019  Volume 126, Issue 6, Page(s) 509

    Language English
    Document type Article
    ZDB-ID 2223586-3
    ISSN 1861-3829
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 194: Show issues

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  2. Article ; Online: Screening for novel plant sources of prenyloxyanthraquinones: Senna alexandrina Mill. and Aloe vera (L.) Burm. F.

    Epifano, Francesco / Fiorito, Serena / Locatelli, Marcello / Taddeo, Vito Alessandro / Genovese, Salvatore

    Natural product research

    2015  Volume 29, Issue 2, Page(s) 180–184

    Abstract: ... of Senna alexandrina Mill. (Leguminosae) and leaves and gel of Aloe vera (L.) Burm. F. (Xanthorrhoeaceae ...

    Abstract As a continuation of our ongoing studies aimed to reveal the presence of oxyprenylated anthraquinones in plants claimed to have a laxative effect, in this article, we describe the extraction and HPLC separation of madagascin (3-isopentenyloxyemodin) and 3-geranyloxyemodine from dried leaves and fruits of Senna alexandrina Mill. (Leguminosae) and leaves and gel of Aloe vera (L.) Burm. F. (Xanthorrhoeaceae). Both compounds are described herein for the first time as components of extracts of the title plants.
    MeSH term(s) Aloe/chemistry ; Anthraquinones/chemistry ; Anthraquinones/isolation & purification ; Chromatography, High Pressure Liquid ; Fruit/chemistry ; Hemiterpenes/chemistry ; Hemiterpenes/isolation & purification ; Molecular Structure ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Senna Plant/chemistry
    Chemical Substances 3-geranyloxyemodine ; 3-isopentenyloxyemodin ; Anthraquinones ; Hemiterpenes ; Plant Extracts
    Language English
    Publishing date 2015
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2014.971792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Screening for novel plant sources of prenyloxyanthraquinones: Senna alexandrina Mill. and Aloe vera (L.) Burm. F

    Epifano, Francesco / Fiorito, Serena / Locatelli, Marcello / Taddeo, Vito Alessandro / Genovese, Salvatore

    Natural product research. 2015 Jan. 17, v. 29, no. 2

    2015  

    Abstract: ... of Senna alexandrina Mill. (Leguminosae) and leaves and gel of Aloe vera (L.) Burm. F. (Xanthorrhoeaceae ...

    Abstract As a continuation of our ongoing studies aimed to reveal the presence of oxyprenylated anthraquinones in plants claimed to have a laxative effect, in this article, we describe the extraction and HPLC separation of madagascin (3-isopentenyloxyemodin) and 3-geranyloxyemodine from dried leaves and fruits of Senna alexandrina Mill. (Leguminosae) and leaves and gel of Aloe vera (L.) Burm. F. (Xanthorrhoeaceae). Both compounds are described herein for the first time as components of extracts of the title plants.
    Keywords Aloe vera ; Senna alexandrina ; anthraquinones ; fruits ; gels ; high performance liquid chromatography ; leaves ; screening
    Language English
    Dates of publication 2015-0117
    Size p. 180-184.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2014.971792
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Blinatumomab before allogeneic stem cell transplantation: the ideal strategy to improve patient's outcomes?

    Locatelli, Franco

    Transplantation and cellular therapy

    2023  Volume 30, Issue 2, Page(s) 129–130

    MeSH term(s) Humans ; Hematopoietic Stem Cell Transplantation ; Antibodies, Bispecific/therapeutic use
    Chemical Substances blinatumomab (4FR53SIF3A) ; Antibodies, Bispecific
    Language English
    Publishing date 2023-10-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2024.01.061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5082: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Is the age of vincristine/steroid pulses over?

    Locatelli, Franco

    Blood

    2023  Volume 141, Issue 24, Page(s) 2914–2915

    MeSH term(s) Child ; Humans ; Vincristine ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Steroids ; B-Lymphocytes
    Chemical Substances Vincristine (5J49Q6B70F) ; Steroids
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023020241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 364: Show issues

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  6. Article: Anemia of hemodialysis patients: evaluation of the effect of BK-F polymethylmethacrylate membrane.

    Locatelli, F / Andrulli, S / Del Vecchio, L

    Contributions to nephrology

    1999  Volume 125, Page(s) 173–181

    MeSH term(s) Adult ; Aged ; Anemia/drug therapy ; Anemia/etiology ; Anemia/prevention & control ; Biocompatible Materials/chemistry ; Biological Factors/isolation & purification ; Biological Factors/pharmacology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Erythroid Precursor Cells/drug effects ; Erythropoietin/therapeutic use ; Female ; Humans ; Hypoxia/etiology ; Hypoxia/prevention & control ; Informed Consent ; Male ; Membranes, Artificial ; Middle Aged ; Permeability ; Polymethyl Methacrylate/chemistry ; Recombinant Proteins/therapeutic use ; Renal Dialysis/adverse effects ; Renal Dialysis/instrumentation ; Uremia/blood ; Uremia/complications ; Uremia/therapy
    Chemical Substances Biocompatible Materials ; Biological Factors ; Membranes, Artificial ; Recombinant Proteins ; Erythropoietin (11096-26-7) ; Polymethyl Methacrylate (9011-14-7)
    Language English
    Publishing date 1999-01-15
    Publishing country Switzerland
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ISSN 0302-5144
    ISSN 0302-5144
    DOI 10.1159/000059958
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Short and long-term exposure of CNS cell lines to BPA-f a radiosensitizer for boron neutron capture therapy: safety dose evaluation by a battery of cytotoxicity tests.

    De Simone, U / Manzo, L / Ferrari, C / Bakeine, J / Locatelli, C / Coccini, T

    Neurotoxicology

    2013  Volume 35, Page(s) 84–90

    Abstract: Despite the current clinical use of boronophenylalanine-fructose (BPA-f), as radiosensitizer ... We evaluated the potential risk of primary BPA-f toxicity before neutronic irradiation at different ... effects after short-term exposure (4h) to any of BPA-f concentrations tested in all cell models; (ii) dose ...

    Abstract Despite the current clinical use of boronophenylalanine-fructose (BPA-f), as radiosensitizer, in BNCT application for brain tumors, still remains to be determined the safety dose of this agent. We evaluated the potential risk of primary BPA-f toxicity before neutronic irradiation at different concentrations (0-100μgBeq/ml) after short- and long-term exposure (4-48h and 7-10 days), using a battery of tests (i.e. MTT assay, calcein-AM/Propidium Iodide staining, clonogenic test) in CNS cell models (D384 and SH-SY5Y), and non-neuronal primary human fibroblasts (F26). MTT data showed: (i) no cytotoxic effects after short-term exposure (4h) to any of BPA-f concentrations tested in all cell models; (ii) dose- and time-dependent mitochondrial activity impairment in D384 and SH-SY5Y cells only (with 60% and 40% cell death in D384 and SH-SY5Y, respectively, after 48h exposure to BPA-f 100μgBeq/ml). By Calcein-AM/PI staining, BPA-f treatment was specific toward SH-SY5Y cells only: a dose-dependent cell density reduction was observed, with a more pronounced effect after 48h exposure (15-40% at doses ranging 20-100μgBeq/ml). Clonogenic data revealed dose-dependent decrease of cell proliferative capacity in all cell lines, still the SH-SY5Y cells were the most sensitive ones: the lowest dose (20μgBeq/ml) produced 90% cell decrease. These results indicate dose- and time-dependent cytotoxic effects of BPA-f, with CNS cells showing a lower tolerance compared to fibroblasts. Long-term exposure to BPA-f compromised the proliferative capacity regardless of cell model type (cell sensitivity being SH-SY5Y>D384>F26). In short-time exposure, BPA-f exhibits a safe dosage up to 40μgBeq/ml for the viability of CNS cell lines.
    MeSH term(s) Boron Compounds/toxicity ; Boron Neutron Capture Therapy/methods ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Fibroblasts/drug effects ; Fibroblasts/pathology ; Fructose/analogs & derivatives ; Fructose/toxicity ; Humans ; Mitochondria/drug effects ; Mitochondria/pathology ; Neurons/drug effects ; Neurons/pathology ; Radiation-Sensitizing Agents/toxicity ; Risk Assessment ; Time Factors ; Toxicity Tests
    Chemical Substances 4-boronophenylalanine-fructose ; Boron Compounds ; Radiation-Sensitizing Agents ; Fructose (30237-26-4)
    Language English
    Publishing date 2013-03
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 800820-6
    ISSN 1872-9711 ; 0161-813X
    ISSN (online) 1872-9711
    ISSN 0161-813X
    DOI 10.1016/j.neuro.2012.12.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1547: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Development of Rhyzopertha dominica (F.) (Coleoptera Bostrichidae) on durum wheat kernels and semolina

    Lidia Limonta / Matteo Carlo Morosini / Daria Patrizia Locatelli

    Journal of Entomological and Acarological Research, Vol 43, Iss 1, Pp 33-

    2011  Volume 38

    Abstract: he time necessary to larvae of Rhyzopertha dominica to drill kernels with or without dusts (semolina or debris from adults), and the possibility of development on semolina were evaluated. T ests were carried out on durum wheat kernels ( Triticum durum ... ...

    Abstract he time necessary to larvae of Rhyzopertha dominica to drill kernels with or without dusts (semolina or debris from adults), and the possibility of development on semolina were evaluated. T ests were carried out on durum wheat kernels ( Triticum durum Desfontaines), debris deriving from rearing, and semolina. Development was observed also on 0.5 and 6 mm of semolina and of debris. T hirty replicates were carried out for each test. The number of first instar larvae, that successfully drill sound kernels within 10 days, was higher by adding semolina or debris. When only kernels were provided, the time needed to larvae to drill increased. Development and the number of emerging adults were not significantly influenced by the addition of semolina to the kernels. Larvae couldn’t develop on 0.5 mm, while an equal number of individuals completed the development to adult in 6 mm of semolina as in the tests with kernels. When development was on debris, a lower number of emerged adults was observed.
    Keywords Lesser grain borer ; cereal grain ; flour ; debris ; Zoology ; QL1-991
    Language English
    Publishing date 2011-04-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article ; Online: Cardio-renoprotective effects of SGLT2 inhibitors - the role of anaemia correction.

    Locatelli, Francesco / Del Vecchio, Lucia

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2024  

    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfae019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2198: Show issues Location:
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    Zs.MO 329: Show issues

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  10. Book: Current and future challenges in anaemia management

    Locatelli, Francesco

    (Nephrology, dialysis, transplantation ; 20, Suppl. 6)

    2005  

    Author's details guest ed. Locatelli
    Series title Nephrology, dialysis, transplantation ; 20, Suppl. 6
    Collection
    Language English
    Size vi43 S. : graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT014447402
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 2198 -20,Suppl.6- not available for loan Zeitschriften-Lesesaal

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