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  1. AU=Gohil R
  2. AU="Zhengyi, Wu"
  3. AU=Wessels J A M
  4. AU="Porter, Lavinia"
  5. AU=Al-Mayman Sulaiman

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  1. Buch ; Online: R Data Visualization Cookbook

    Gohil, Atmajitsinh

    2015  

    Abstract: ... about data visualization, this book is for you. Basic knowledge of R programming is expected ...

    Abstract If you are a data journalist, academician, student or freelance designer who wants to learn about data visualization, this book is for you. Basic knowledge of R programming is expected
    Sprache Englisch
    Umfang Online-Ressource (236 p)
    Verlag Packt Publishing
    Erscheinungsort Birmingham
    Dokumenttyp Buch ; Online
    Anmerkung Description based upon print version of record
    ISBN 9781783989508 ; 1783989505
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  2. Artikel: Adrenaline before Unconventional Therapy for Status Asthamaticus.

    Gohil, Jayendra R

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2019  Band 23, Heft 10, Seite(n) 492

    Abstract: How to cite this article: ...

    Abstract How to cite this article:
    Sprache Englisch
    Erscheinungsdatum 2019-08-19
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23273
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Histopathological Validation of Microvascular Anastomosis using Two-Throw Reef Knots - An Experimental Study.

    Gohil, Dhaval / Mahadevan, Anita / Prabhuraj, A R / Pruthi, Nupur

    Neurology India

    2024  Band 71, Heft 6, Seite(n) 1172–1176

    Abstract: Background: Knot configuration is an important but relatively neglected topic in microvascular anastomosis literature.: Objective: To study the differences between end-to-end microvascular anastomosis performed with two-throw reef knots as compared ... ...

    Abstract Background: Knot configuration is an important but relatively neglected topic in microvascular anastomosis literature.
    Objective: To study the differences between end-to-end microvascular anastomosis performed with two-throw reef knots as compared to traditional three-throw knots in a rat femoral artery model at the histological level.
    Material and methods: Sprague Dawley rats underwent end-to-end microvascular anastomosis of the right femoral artery (one-way-up method). The rats were divided into two groups: two-throw reef knots versus traditional three-throw knots. The patency was checked by the standard empty refill method. After 2 weeks, the rats underwent re-exploration. An anastomotic segment was sent for histological analysis. Histological alterations including luminal patency and changes in Tunica intima, Tunica media, and Tunica adventitia were compared between the two groups.
    Results: Twenty-nine rats were operated on by the senior author (17 by three-throw and 12 by two-throw reef knots). In the two-throw reef knot group versus the traditional three-throw knot group, the immediate patency rates were 100% versus 82.4%, and the delayed patency rates were 90.9% versus 62.5%, respectively. The histopathological patency rates were concordant with delayed patency rates. Subintimal proliferation and fibrosis were comparable in both groups. Adventitial granulomas were noted in all, irrespective of the knotting technique. Tunica media preservation rates for the two-throw reef knot versus the traditional three-throw knot group were 63.6% versus 0%. Five rats were operated by the beginner in the field, all by two-throw reef knots (to assess the safety of this new method in the hands of a beginner).
    Conclusion: Microvascular anastomosis performed with two-throw reef knots appears not only feasible but better in terms of anastomosis patency. Histological superiority in terms of Tunica media preservation further validates the technique.
    Mesh-Begriff(e) Rats ; Animals ; Rats, Sprague-Dawley ; Suture Techniques ; Anastomosis, Surgical/methods ; Femoral Artery/surgery
    Sprache Englisch
    Erscheinungsdatum 2024-01-04
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.391390
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Initial validation of the powered mobility device autonomy residential screen (PoMoDARS).

    Dickson, Natalie C / Gohil, Apeksha R / Unsworth, Carolyn A

    Scandinavian journal of occupational therapy

    2023  , Seite(n) 1–11

    Abstract: Background: The Powered Mobility Device Autonomy Residential Screen (PoMoDARS) is a new tool to enable clinicians to screen resident capacity and performance skills for powered mobility device (PMD) use in residential aged care settings. The PoMoDARS is ...

    Abstract Background: The Powered Mobility Device Autonomy Residential Screen (PoMoDARS) is a new tool to enable clinicians to screen resident capacity and performance skills for powered mobility device (PMD) use in residential aged care settings. The PoMoDARS is context specific, time efficient and promotes resident autonomy and safety.
    Aims: To (i) undertake initial face and content validation of the PoMoDARS, and (ii) use the research findings to make any modifications.
    Methods: A mixed-methods study design, underpinned by Classical Test Theory. Eight clinicians completed 20 PoMoDARS screens and provided both quantitative and qualitative feedback on item importance and ease of use within a formal interview.
    Results: Initial face and content validity of the PoMoDARS were supported, with small modifications made to item descriptors and instructions.
    Conclusions: The PoMoDARS has been developed for use in residential aged care settings to screen resident PMD use. While initial validation has been undertaken, further studies to determine the reliability of the tool and continue the validation process are required.
    Significance: Older adults in residential aged care facilities benefit greatly from the autonomy gained through PMD use. The PoMoDARS promotes collaboration between occupational therapists, nurses, and the wider team to support residents and safe PMD use.
    Sprache Englisch
    Erscheinungsdatum 2023-11-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2144132-7
    ISSN 1651-2014 ; 1103-8128
    ISSN (online) 1651-2014
    ISSN 1103-8128
    DOI 10.1080/11038128.2023.2260834
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  5. Artikel ; Online: Powered mobility device use in residential aged care: a retrospective audit of incidents and injuries.

    Dickson, Natalie C / Gohil, Apeksha R / Unsworth, Carolyn A

    BMC geriatrics

    2023  Band 23, Heft 1, Seite(n) 363

    Abstract: Background: Powered wheelchairs and motorised mobility scooters, collectively called powered mobility devices (PMD), are highly valued by older Australians, including those living in residential care, to facilitate personal and community mobility. The ... ...

    Abstract Background: Powered wheelchairs and motorised mobility scooters, collectively called powered mobility devices (PMD), are highly valued by older Australians, including those living in residential care, to facilitate personal and community mobility. The number of PMDs in residential aged care is expected to grow proportionally with that of the wider community, however, there is very little literature on supporting residents to use PMDs safely. Prior to developing such supports, it is important to understand the frequency and nature of any incidents experienced by residents whilst using a PMD. The aim of this study was to determine the number and characteristics of PMD use related incidents occurring in a group of residential aged care facilities in a single year in one state in Australia including incident type, severity, assessment, or training received and outcomes on follow-up for PMD users living in residential aged care.
    Methods: Analysis of secondary data, including documentation of PMD incidents and injuries for one aged care provider group over 12 months retrospectively. Follow-up data were gathered 9-12 months post incident to review and record the outcome for each PMD user.
    Results: No fatalities were recorded as a direct result of PMD use and 55 incidents, including collisions, tips, and falls, were attributed to 30 residents. Examination of demographics and incident characteristics found that 67% of residents who had incurred incidents were male, 67% were over 80 years of age, 97% had multiple diagnoses and 53% had not received training to use a PMD. Results from this study were extrapolated to project that 4,453 PMD use related incidents occur every year within Australian residential aged care facilities, with the potential for outcomes such as extended recovery, fatality, litigation, or loss of income.
    Conclusion: This is the first time that detailed incident data on PMD use in residential aged care has been reviewed in an Australian context. Illuminating both the benefits and the potential risks of PMD use emphasizes the need to develop and improve support structures to promote safe PMD use in residential aged care.
    Mesh-Begriff(e) Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Australia/epidemiology ; Homes for the Aged ; Retrospective Studies ; Self-Help Devices ; Wheelchairs ; Accidents
    Sprache Englisch
    Erscheinungsdatum 2023-06-11
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-023-04073-z
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  6. Artikel ; Online: Base Excision Repair: Mechanisms and Impact in Biology, Disease, and Medicine.

    Gohil, Dhara / Sarker, Altaf H / Roy, Rabindra

    International journal of molecular sciences

    2023  Band 24, Heft 18

    Abstract: Base excision repair (BER) corrects forms of oxidative, deamination, alkylation, and abasic single-base damage that appear to have minimal effects on the helix. Since its discovery in 1974, the field has grown in several facets: mechanisms, biology and ... ...

    Abstract Base excision repair (BER) corrects forms of oxidative, deamination, alkylation, and abasic single-base damage that appear to have minimal effects on the helix. Since its discovery in 1974, the field has grown in several facets: mechanisms, biology and physiology, understanding deficiencies and human disease, and using BER genes as potential inhibitory targets to develop therapeutics. Within its segregation of short nucleotide (SN-) and long patch (LP-), there are currently six known global mechanisms, with emerging work in transcription- and replication-associated BER. Knockouts (KOs) of BER genes in mouse models showed that single glycosylase knockout had minimal phenotypic impact, but the effects were clearly seen in double knockouts. However, KOs of downstream enzymes showed critical impact on the health and survival of mice. BER gene deficiency contributes to cancer, inflammation, aging, and neurodegenerative disorders. Medicinal targets are being developed for single or combinatorial therapies, but only PARP and APE1 have yet to reach the clinical stage.
    Mesh-Begriff(e) Humans ; Animals ; Mice ; Mice, Knockout ; Medicine ; Aging ; DNA Repair ; Biology
    Sprache Englisch
    Erscheinungsdatum 2023-09-16
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241814186
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Spinal Rosai-Dorfman disease-a report of 2 cases and review of literature.

    Basu, Saumyajit / Gala, Rohan / Gohil, Kushal

    Spinal cord series and cases

    2023  Band 9, Heft 1, Seite(n) 36

    Abstract: Introduction: Rosai-Dorfman Disease (RDD) is a rare benign histiocytic disease that infrequently affects the spine. We report two cases of spinal RDD and review the relevant literature. This report addresses the various diagnostic dilemmas related to ... ...

    Abstract Introduction: Rosai-Dorfman Disease (RDD) is a rare benign histiocytic disease that infrequently affects the spine. We report two cases of spinal RDD and review the relevant literature. This report addresses the various diagnostic dilemmas related to the evaluation of Spinal RDD and its treatment.
    Case presentation: Case 1: A 32-year-old male presented with low back pain and left anterior thigh for last 8 months. On examination, there was sensory diminution on inner aspects of the thigh with an absent left knee jerk. CT/MRI scans revealed an extradural lesion at L2/3 with neural compression. PET scan showed several hypermetabolic lesions in ribs, humerus, femur, and vertebrae. He underwent en bloc excision of the extradural mass with L2-3 pedicle screw-rod fixation and was later managed with chemotherapy. Case 2: A 42-year-old male presented with spastic paraparesis with urinary incontinence for the last 4 weeks. On examination, he had a neurological level of T6. MRI scan revealed a lesion in posterior elements of T6-7 compressing the spinal cord. He underwent T6-7 laminectomy with decompression. In both cases, the diagnosis was confirmed by histopathology and further managed by Hemato-oncologist. They both did well at 1-year follow-up with improvement in neurology.
    Discussion: Spinal RDD to date remains a large diagnostic dilemma with no pathognomonic clinical or radiological features; mimicking many osteolytic lesions in the spine. The diagnosis is purely histopathological and immunological. The lesion's complete surgical excision is the mainstay of treatment with a better prognosis and decreased chances of recurrences.
    Mesh-Begriff(e) Male ; Humans ; Adult ; Histiocytosis, Sinus/diagnosis ; Histiocytosis, Sinus/surgery ; Spine ; Spinal Cord ; Laminectomy ; Femur
    Sprache Englisch
    Erscheinungsdatum 2023-07-29
    Erscheinungsland England
    Dokumenttyp Review ; Case Reports ; Journal Article
    ISSN 2058-6124
    ISSN (online) 2058-6124
    DOI 10.1038/s41394-023-00600-7
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  8. Artikel ; Online: The impact of surgical set-up of endoscopic two surgeon four hand anterior skull base surgeries on surgeons' ergonomics.

    Maniam, Pavithran / Lucocq, James / Gohil, Rohit / Rokade, Ashok

    Journal of neurosurgical sciences

    2023  

    Abstract: Background: The impact of different surgical set-ups of endoscopic two surgeon four hand anterior skull base surgeries on surgeons' ergonomics remain unclear. This study aims to explore the effect of surgeon, patient and surgical screen positioning on ... ...

    Abstract Background: The impact of different surgical set-ups of endoscopic two surgeon four hand anterior skull base surgeries on surgeons' ergonomics remain unclear. This study aims to explore the effect of surgeon, patient and surgical screen positioning on surgeons' ergonomics using the Rapid Entire Body Assessment (REBA) tool.
    Methods: A total of 20 different surgical positions of anterior skull base surgery were simulated and the ergonomic impact on surgeons' neck, truck, leg and wrist were measured using the validated Rapid Entire Body Assessment (REBA) tool. To investigate the ergonomic effect of different surgical setups, the operating surgeon, assisting surgeon, patient head, camera and screen positions were positioned differently in each surgical position.
    Results: The lowest REBA Score recorded is 3 whereas the highest score is 8. The REBA scores for the majority of positions are 3 highlighting that these positions are ergonomically favorable. Position 12 is the least ergonomically favorable position with a total REBA score of 19. In this position, operating surgeon is positioned to the right of the patient, assisting surgeon to the left of patient, patient head in central position with camera held by operating surgeon and one screen is placed to the right of patient. Positions 13 and 17 are the most ergonomically favorable positions with a total REBA score of 12. In these positions, the patient's head is positioned to the center, two screens were utilized, and the surgeons were positioned on either side of the patient. The utilization of 2 screens with a central patient head position with the surgeons placed on either side of the patient contribute towards a more ergonomically state in these positions.
    Conclusions: Certain positional behaviors are better at reducing musculoskeletal injury risk when compared to other. Positions with two screens and central head positions are more favourable ergonomically and surgeons should consider this set-up to reduce musculoskeletal injuries during anterior skull base surgery.
    Sprache Englisch
    Erscheinungsdatum 2023-05-09
    Erscheinungsland Italy
    Dokumenttyp Journal Article
    ZDB-ID 193139-8
    ISSN 1827-1855 ; 0390-5616 ; 0026-4881
    ISSN (online) 1827-1855
    ISSN 0390-5616 ; 0026-4881
    DOI 10.23736/S0390-5616.23.05991-X
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  9. Artikel ; Online: A Brief Review on Murraya paniculata (Orange Jasmine)

    Deepa Joshi / Kashmira J. Gohil

    Journal of Pharmacopuncture, Vol 26, Iss 1, Pp 10-

    pharmacognosy, phytochemistry and ethanomedicinal uses

    2023  Band 17

    Abstract: Objectives: Murraya paniculata (family-Rutaceae), popularly known as orange jasmine, is the most important evergreen plant. The Rutaceae family is economically significant due to its diverse edible fruits and essential oils.Methods : : Murraya paniculata ...

    Abstract Objectives: Murraya paniculata (family-Rutaceae), popularly known as orange jasmine, is the most important evergreen plant. The Rutaceae family is economically significant due to its diverse edible fruits and essential oils.Methods : : Murraya paniculata extracts (MPE) of leaf have been shown to include phenolic compounds, highly oxygenated flavonoids, flavanones, sesquiterpenoids, polymethoxy glycosides, and coumarins. Cyclocitral, methyl salicylate, trans-nerolidol, cubenol, isogermacrene, -cadinol, and cubeb-11-ene are all abundant in MPE. The usages of various parts of this plant, such as bark, leaves and flower, as a remedy for a variety of ailments as widely recorded in the traditional literature. The plant has anti-diabetic, anti-obesity, antibacterial, anti-implantation, anti-oxidative, cytotoxic, anti-diarrheal, antidepressant and anti-anxiety properties and many others.Results : : The goal of the review is to reignite interest in this potential plant, encouraging researchers to continue their research in order to uncover novel therapeutic compounds for the treatment and management of a range of infections. The current review provided a comprehensive overview of this traditional unique plant.Conclusion : : The review paves a way for exploring its active chemical elements with substantial pharmacological values further for potential benefits of mankind.
    Schlagwörter herbal plants ; murraya paniculata ; therapeutic uses ; Medicine ; R ; Miscellaneous systems and treatments ; RZ409.7-999 ; Therapeutics. Pharmacology ; RM1-950
    Thema/Rubrik (Code) 580
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag Korean Pharmacopuncture Institute
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Exploring the potential of phage and their applications.

    Khambhati, Khushal / Bhattacharjee, Gargi / Gohil, Nisarg / Maurya, Rupesh / Singh, Vijai

    Progress in molecular biology and translational science

    2023  Band 200, Seite(n) 1–12

    Abstract: Antibiotic resistant microorganisms are significantly increasing due to horizontal gene transfer, mutation and overdose of antibiotics leading to serious health conditions globally. Several multidrug resistant microorganisms have shown resistance to even ...

    Abstract Antibiotic resistant microorganisms are significantly increasing due to horizontal gene transfer, mutation and overdose of antibiotics leading to serious health conditions globally. Several multidrug resistant microorganisms have shown resistance to even the last line of antibiotics making it very difficult to treat them. Besides using antibiotics, an alternative approach to treat such resistant bacterial pathogens through the use of bacteriophage (phage) was used in the early 1900s which however declined and vanished after the discovery of antibiotics. In recent times, phage has emerged and gained interest as an alternative approach to antibiotics to treat MDR pathogens. Phage can self-replicate by utilizing cellular machinery of bacterial host by following lytic and lysogenic life cycles and therefore suitable for rapid regeneration. Application of phage for detection of bacterial pathogens, elimination of bacteria, agents for controlling food spoilage, treating human disease and several others entitles phage as a futuristic antibacterial armamentarium.
    Mesh-Begriff(e) Humans ; Bacteriophages ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Food ; Mutation
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2023-05-11
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2471995-X
    ISSN 1878-0814 ; 0079-6603 ; 1877-1173
    ISSN (online) 1878-0814
    ISSN 0079-6603 ; 1877-1173
    DOI 10.1016/bs.pmbts.2023.04.001
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