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  1. Article ; Online: Analysis of influencing factors of HPV vaccination willingness of female sex workers in urban entertainment venues based on the IMB model in Guangxi, China.

    He, Zhi-Yan / Wei, Jun-Hong / Jiang, Jian-Ming / Hu, Rui / Qi, Guang-Zi

    BMC women's health

    2024  Volume 24, Issue 1, Page(s) 141

    Abstract: Objective: Understanding HPV vaccination willingness and its influencing factors among female sex workers (FSWs) in entertainment venues in an urban area of Guangxi, China.: Methods: From 15 August to 15 October 2022, FSWs in entertainment venues ... ...

    Abstract Objective: Understanding HPV vaccination willingness and its influencing factors among female sex workers (FSWs) in entertainment venues in an urban area of Guangxi, China.
    Methods: From 15 August to 15 October 2022, FSWs in entertainment venues with commercial sex trade in an urban area of Guangxi were selected as the study subjects for the questionnaire survey using the method of intentional sampling. The questionnaire based on the information-motivation-behavior (IMB) skills model was used to collect the basic characteristics, HPV and HPV vaccine-related information and cognition, motivation to vaccinate, behavioral skills and willingness to vaccinate from the research targets. A multifactor logistic regression model was used to analyze the factors influencing the research targets' willingness to receive HPV vaccination.
    Results: Of the 921 research targets, 712 (77.31%) were willing to receive HPV vaccination. The higher the level of knowledge regarding HPV and HPV vaccine-related information, the higher the motivation for HPV vaccination. In addition, the higher the behavioral skills score, the higher the willingness of FSWs in entertainment venues to receive HPV vaccination (P<0.001). FSWs in entertainment venues with lower venue grades [OR(95% CI)=0.693 (0.539, 0.891), P=0.004] were more reluctant to receive HPV vaccination. Those who favored the effectiveness of the vaccine in preventing the disease [OR(95% CI)=2.144 (1.449, 3.174), P<0.001] and those who had heard of HPV vaccine [OR(95% CI)=2.105 (1.451, 3.054), P<0.001], were able to perceive the benefits of HPV vaccination [OR(95% CI)=1.134 (1.045, 1.230), P=0.002]. These individuals acquired greater behavioral skills i.e., self-decision making for HPV vaccination [OR(95% CI)=1.130 (1.008, 1.267), P=0.036] and self-efficacy [OR(95% CI)=1.135 (1.081, 1.191), P<0.001] and they were more willing to receive HPV vaccine.
    Conclusions: There was a relatively high HPV vaccination willingness among FSWs in entertainment venues in an urban area of Guangxi, China. Attention should be focused on introducing the benefits of primary prevention measures such as the HPV vaccine for individuals and behavioral skills for HPV vaccination in order to increase their willingness to be vaccinated thus increasing their HPV vaccination rate.
    MeSH term(s) Humans ; Female ; Sex Workers ; Sex Work ; Motivation ; Papillomavirus Infections/prevention & control ; China ; Surveys and Questionnaires ; Papillomavirus Vaccines/therapeutic use ; Vaccination ; Health Knowledge, Attitudes, Practice ; Patient Acceptance of Health Care
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050444-5
    ISSN 1472-6874 ; 1472-6874
    ISSN (online) 1472-6874
    ISSN 1472-6874
    DOI 10.1186/s12905-024-02962-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mitochondrial genome and phylogenetic analysis of

    Wu, Li-Hong / Wei, Zhi-Yan / Hu, Chao-Xing

    Mitochondrial DNA. Part B, Resources

    2020  Volume 5, Issue 3, Page(s) 3631–3632

    Abstract: We sequenced and annotated mitochondrial genome (mitogenome) of oilseed rape ... ...

    Abstract We sequenced and annotated mitochondrial genome (mitogenome) of oilseed rape pest
    Language English
    Publishing date 2020-10-27
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2020.1832597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Controllability on impulsive systems with delays in both input and impulse and its applications to multi-agent networks.

    Yan, Jiayuan / Hu, Bin / Guan, Zhi-Hong

    ISA transactions

    2024  

    Abstract: This paper investigates the controllability of impulsive systems with input delay and impulse delay and its applications in multi-agent networks. We adopt the geometric and algebraic analytical tools to establish some easily verified controllability ... ...

    Abstract This paper investigates the controllability of impulsive systems with input delay and impulse delay and its applications in multi-agent networks. We adopt the geometric and algebraic analytical tools to establish some easily verified controllability conditions for the considered system model. First, the analytic solution of the considered system is established on every impulsive interval by using ordinary differential equation theory. Then, according to the solution derived, some sufficient complete controllability criteria are developed to reveal the role of the Gramian matrices in different subintervals. By introducing a row matrix of different kinds of Gramian matrices, a complete controllability condition that is proved to be necessary and sufficient is further obtained. By using the relevant geometric matrix theory, the derived algebraic controllability condition is then converted to a geometric one. On other hand, we introduce a multi-agent network with delayed input and impulse and investigate its controllability. By resorting to graph theory and matrix theory, several factors affecting the controllability of the considered multi-agent networks are investigated, such as the topology structure, the inner coupling matrix, and the dynamics of each agent. Finally, two numerical examples are worked out to verify the derived controllability criteria.
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2024.03.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pharmacokinetics of remimazolam after intravenous infusion in anaesthetised children.

    Gao, Yu-Qing / Ihmsen, Harald / Hu, Zhi-Yan / Sun, Wei / Fang, Yu-Bo / Wang, Zhen / Schüttler, Jürgen / Jeleazcov, Christian / Liu, Hua-Cheng

    British journal of anaesthesia

    2023  Volume 131, Issue 5, Page(s) 914–920

    Abstract: Background: The pharmacokinetic properties of the new benzodiazepine remimazolam have been studied only in adults. We investigated the pharmacokinetics of remimazolam after i.v. infusion in anaesthetised paediatric patients.: Methods: Twenty-four ... ...

    Abstract Background: The pharmacokinetic properties of the new benzodiazepine remimazolam have been studied only in adults. We investigated the pharmacokinetics of remimazolam after i.v. infusion in anaesthetised paediatric patients.
    Methods: Twenty-four children (2-6 yr, ASA physical status 1-2, BMI 15-18 kg m
    Results: Pharmacokinetics were best described by a three-compartment model for remimazolam and a two-compartment model for CNS7054 linked by a transit compartment. Remimazolam showed a high clearance of 15.9 (12.9, 18.2) ml kg
    Conclusions: Remimazolam in children was characterised by a high clearance and short context-sensitive half-time. When normalised to weight, pharmacokinetic properties were similar to those reported for adults.
    Clinical trial registration: ChiCTR2200057629.
    MeSH term(s) Adult ; Child ; Humans ; Anesthesia, General ; Benzodiazepines ; Infusions, Intravenous ; Kinetics
    Chemical Substances Benzodiazepines (12794-10-4) ; remimazolam (7V4A8U16MB)
    Language English
    Publishing date 2023-09-21
    Publishing country England
    Document type Clinical Trial ; Journal Article
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2023.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Clinical Outcomes of Tanezumab With Different Dosages for Patient With Osteoarthritis: Network Meta-Analysis.

    Hu, Rui / Song, Ya-Feng / Yang, Zhi-Yan / Zhang, Chao / Tan, Bo

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 614753

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-06-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.614753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Arabinoxylan of varied structural features distinctively affects the functional and in vitro digestibility of wheat starch

    Kang, Ji / Huang-Fu, Zhi-Yan / Tian, Xiaona / Cheng, Liting / Zhang, Jixiang / Liu, Yan / Liu, Yanfang / Wang, Shujun / Hu, Xinzhong / Zou, Liang / Guo, Qingbin

    Food Hydrocolloids. 2023 July, v. 140 p.108615-

    2023  

    Abstract: This study explored the effects of wheat bran arabinoxylan (AX) of various molecular structures on the functional and in vitro digestibility of wheat starch. AX was separated with sequential ethanol precipitation into different fractions (L-Fra and H-Fra) ...

    Abstract This study explored the effects of wheat bran arabinoxylan (AX) of various molecular structures on the functional and in vitro digestibility of wheat starch. AX was separated with sequential ethanol precipitation into different fractions (L-Fra and H-Fra), followed by acidic treatment at varied time to convert L-Fra into different subfractions (H-Sub, M-Sub and L-Sub), and the structural features of AX and its subsequent fractions were compared. The Mw and branching degree of the fractions were decreased in the order of H-Fra (545 kDa, 1.15), L-Fra (86 kDa, 0.35), H-Sub (38 kDa, 0.16), M-Sub (21 kDa, 0.10) and L-Sub (7 kDa, 0.08). The functional properties, such as pasting properties, rheological properties, thermal properties, and their effect on the in vitro digestibility of wheat starch-AX combinations, were closely related to the molecular structures of AX. AX with higher Mw, higher branching degree and phenolic content could better inhibit the starch gelatinization and retrogradation, thus reducing the apparent viscosity and gelling properties of wheat starch. The possible mechanisms can be illustrated as 1) AX could compete for water with starch to inhibit granule expansion; 2) AX could not only adsorb on the surface of starch granules through hydrogen bonds but also entangle with the leached amylose and wrap on the surface of granules; 3) AX contained phenols, leading them to inhibit granule expansion through non-covalent interactions with starch molecules. Overall, this study provides a theoretical basis to improve the quality of wheat starch foods and extend the shelf life of wheat foods.
    Keywords amylose ; arabinoxylan ; digestibility ; ethanol ; gelatinization ; hydrocolloids ; hydrogen ; retrogradation ; shelf life ; viscosity ; wheat ; wheat bran ; wheat starch ; Molecular structure ; Physicochemical properties
    Language English
    Dates of publication 2023-07
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 742742-6
    ISSN 1873-7137 ; 0268-005X
    ISSN (online) 1873-7137
    ISSN 0268-005X
    DOI 10.1016/j.foodhyd.2023.108615
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Tumor bud-derived CCL5 recruits fibroblasts and promotes colorectal cancer progression via CCR5-SLC25A24 signaling.

    Gao, Ling-Fang / Zhong, Yan / Long, Ting / Wang, Xia / Zhu, Jia-Xian / Wang, Xiao-Yan / Hu, Zhi-Yan / Li, Zu-Guo

    Journal of experimental & clinical cancer research : CR

    2022  Volume 41, Issue 1, Page(s) 81

    Abstract: Background: Tumor budding is included in the routine diagnosis of colorectal cancer (CRC) and is considered a tumor prognostic factor independent of TNM staging. This study aimed to identify the fibroblast-mediated effect of tumor bud-derived C-C ... ...

    Abstract Background: Tumor budding is included in the routine diagnosis of colorectal cancer (CRC) and is considered a tumor prognostic factor independent of TNM staging. This study aimed to identify the fibroblast-mediated effect of tumor bud-derived C-C chemokine ligand 5 (CCL5) on the tumor microenvironment (TME).
    Methods: Recruitment assays and a human cytokine array were used to detect the main cytokines that CRC tumor buds secrete to recruit fibroblasts. siRNA transfection and inhibitor treatment were used to investigate the role of fibroblast CCL5 receptors in fibroblast recruitment. Subsequently, transcriptome sequencing was performed to explore the molecular changes occurring in fibroblasts upon stimulation with CCL5. Finally, clinical specimens and orthotopic xenograft mouse models were studied to explore the contribution of CCL5 to angiogenesis and collagen synthesis.
    Results: Hematoxylin-eosin staining and immunochemistry revealed a higher number of fibroblasts at the invasive front of CRC tissue showing tumor budding than at sites without tumor budding. In vitro experiments demonstrated that CCL5 derived from tumor buds could recruit fibroblasts by acting on the CCR5 receptors on fibroblasts. Tumor bud-derived CCL5 could also positively regulate solute carrier family 25 member 24 (SLC25A24) expression in fibroblasts, potentially activating pAkt-pmTOR signaling. Moreover, CCL5 could increase the number of α-SMA
    Conclusions: At the invasive front of CRC, tumor bud-derived CCL5 can recruit fibroblasts via CCR5-SLC25A24 signaling, further promoting angiogenesis and collagen synthesis via recruited fibroblasts, and eventually create a tumor-promoting microenvironment. Therefore, CCL5 may serve as a potential diagnostic marker and therapeutic target for tumor budding in CRC.
    MeSH term(s) Animals ; Antiporters/metabolism ; Antiporters/pharmacology ; Calcium-Binding Proteins/metabolism ; Cell Line, Tumor ; Chemokine CCL5/genetics ; Colorectal Neoplasms/pathology ; Endothelial Cells/metabolism ; Fibroblasts/metabolism ; Humans ; Mice ; Mitochondrial Proteins/metabolism ; Receptors, CCR5 ; Signal Transduction ; Tumor Microenvironment
    Chemical Substances Antiporters ; CCL5 protein, human ; CCR5 protein, human ; Calcium-Binding Proteins ; Chemokine CCL5 ; Mitochondrial Proteins ; Receptors, CCR5 ; SLC25A24 protein, human
    Language English
    Publishing date 2022-03-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 803138-1
    ISSN 1756-9966 ; 0392-9078
    ISSN (online) 1756-9966
    ISSN 0392-9078
    DOI 10.1186/s13046-022-02300-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transcriptional regulation of secondary metabolism and autophagy genes in response to DNA replication stress in Setosphaeria turcica

    Ya-nan MENG / Xin-jie ZHANG / Fan-li ZENG / Wei-bo ZHAI / Pan LI / Jing-jing HU / Sheng-lin XIAO / Zhi-min HAO / Zhi-yan CAO / Chuan CHEN / Jin-gao DONG

    Journal of Integrative Agriculture, Vol 22, Iss 4, Pp 1068-

    2023  Volume 1081

    Abstract: The fungal pathogen Setosphaeria turcica causes northern corn leaf blight (NCLB), which leads to considerable crop losses. Setosphaeria turcica elaborates a specialized infection structures called appressorium for maize infection. Previously, we ... ...

    Abstract The fungal pathogen Setosphaeria turcica causes northern corn leaf blight (NCLB), which leads to considerable crop losses. Setosphaeria turcica elaborates a specialized infection structures called appressorium for maize infection. Previously, we demonstrated that the S. turcica triggers an S-phase checkpoint and ATR (Ataxia Telangiectasia and Rad3 related)-dependent self-protective response to DNA genotoxic insults during maize infection. However, how the regulatory mechanism works was still largely unknown. Here, we report a genome wide transcriptional profile analysis during appressorium formation in the present of DNA replication stress. We performed RNA-Seq analysis to identify S. tuicica genes responsive to DNA replication stress. In the current work, we found that appressorium-mediated maize infection by S. turcica is significantly blocked by S-phase checkpoint. A large serial of secondary metabolite and melanin biosynthesis genes were blocked in appressorium formation of S. turcica during the replication stress. The secondary metabolite biosynthesis genes including alcohol dehydrogenase GroES-like domain, multicopper oxidase, ABC-transporter families, cytochrome P450 and FAD-containing monooxygenase were related to plant pathogen infection. In addition, we demonstrated that autophagy in S. turcica is up-regulated by ATR as a defense response to stress. We identified StATG3, StATG4, StATG5, StATG7 and StATG16 genes for autophagy were induced by ATR-mediated S-phase checkpoint. We therefore propose that in response to genotoxic stress, S. turcica utilizes ATR-dependent pathway to turn off transcription of genes governing appressorium-mediated infection, and meanwhile inducing transcription of autophagy genes likely as a mechanism of self-protection, aside from the more conservative responses in eukaryotes.
    Keywords Setosphaeria turcica ; appressorium ; secondary metabolite ; autophagy ; DNA replication stress ; Agriculture (General) ; S1-972
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Insight into the Corrosion Inhibition Mechanism of Sodium Silicate on the Magnesium Alloy Surface: Experimental and Theoretical Calculations.

    Chen, Yang / Xin, Yong / Yan, Hong / Hu, Zhi

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 39, Page(s) 14025–14039

    Abstract: The corrosion inhibition mechanism of sodium silicate (SS) for WE43 magnesium alloy in NaCl solution was investigated by in situ observation, electron probe microanalysis (EPMA), electrochemical test, and theoretical calculations. In situ observation ... ...

    Abstract The corrosion inhibition mechanism of sodium silicate (SS) for WE43 magnesium alloy in NaCl solution was investigated by in situ observation, electron probe microanalysis (EPMA), electrochemical test, and theoretical calculations. In situ observation showed that local corrosion was markedly inhibited after the addition of the SS inhibitor. Electrochemical data revealed that a protective layer was formed on the metal/solution interface and an optimum inhibition efficiency of 98.3% in the case of 2.5 g/L SS. A uniform magnesium silicate layer with a thickness of ∼2 μm formed on the uncorroded area was confirmed. Quantum chemical calculations revealed that SiO
    Language English
    Publishing date 2023-09-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c01816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Two Carboxylate-Cyanurates with Strong Optical Anisotropy and Large Band Gaps.

    Chen, Yan / Hu, Chunli / Fang, Zhi / Mao, Jianggao

    Inorganic chemistry

    2023  Volume 62, Issue 5, Page(s) 2257–2265

    Abstract: The first metal carboxylate-cyanurates, namely, K( ... ...

    Abstract The first metal carboxylate-cyanurates, namely, K(H
    Language English
    Publishing date 2023-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.2c03985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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