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  1. Book ; Online ; E-Book: Drug discovery from mother nature

    Gupta, Subash Chandra / Prasad, Sahdeo / Aggarwal, Bharat B.

    (Advances in experimental medicine and biology ; 929)

    2016  

    Author's details Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal editors
    Series title Advances in experimental medicine and biology ; 929
    Collection
    Keywords Anti-inflammatory Agents ; Chronic Diseases ; Dietary Agents ; Inflammatory Pathways ; Natural Products ; Neutraceuticials
    Language English
    Size 1 Online-Ressource (viii, 410 Seiten)
    Publisher Springer
    Publishing place Cham
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019130003
    ISBN 978-3-319-41342-6 ; 9783319413419 ; 3-319-41342-2 ; 3319413414
    DOI 10.1007/978-3-319-41342-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Anti-inflammatory nutraceuticals and chronic diseases

    Gupta, Subash Chandra / Prasad, Sahdeo / Aggarwal, Bharat B.

    (Advances in experimental medicine and biology ; 928)

    2016  

    Author's details Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal editors
    Series title Advances in experimental medicine and biology ; 928
    Collection
    Keywords Medicine ; Immunology ; Pharmacology ; Food/Biotechnology ; Nutrition
    Subject code 616.079
    Language English
    Size 1 Online-Ressource (viii, 482 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019112423
    ISBN 978-3-319-41334-1 ; 9783319413327 ; 3-319-41334-1 ; 3319413325
    DOI 10.1007/978-3-319-41334-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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    Inter-library loan at ZB MED

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  3. Book: Anti-inflammatory nutraceuticals and chronic diseases

    Gupta, Subash Chandra / Prasad, Sahdeo / Aggarwal, Bharat B.

    (Advances in experimental medicine and biology ; 928)

    2016  

    Author's details Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal editors
    Series title Advances in experimental medicine and biology ; 928
    Collection
    Keywords Anti-inflammatory Agents ; Chronic Diseases ; Dietary Agents ; Inflammatory Pathways ; Natural Products ; Neutraceuticals
    Language English
    Size VIII, 482 Seiten, Illustrationen, Diagramme, 23.5 cm x 15.5 cm, 0 g
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019112430
    ISBN 978-3-319-41332-7 ; 3-319-41332-5 ; 9783319413341 ; 3319413341
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -928- not available for loan Zeitschriften-Lesesaal

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  4. Book: Drug discovery from mother nature

    Gupta, Subash Chandra / Prasad, Sahdeo / Aggarwal, Bharat B.

    (Advances in experimental medicine and biology ; 929)

    2016  

    Author's details Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal editors
    Series title Advances in experimental medicine and biology ; 929
    Collection
    Keywords Anti-inflammatory Agents ; Chronic Diseases ; Dietary Agents ; Inflammatory Pathways ; Natural Products ; Neutraceuticials
    Language English
    Size viii, 410 Seiten, Illustrationen, Diagramme, 23.5 cm x 15.5 cm, 0 g
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019112445
    ISBN 978-3-319-41341-9 ; 3-319-41341-4 ; 9783319413426 ; 3319413422
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -929- not available for loan Zeitschriften-Lesesaal

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  5. Article ; Online: Zinc-curcumin based complexes in health and diseases: An approach in chemopreventive and therapeutic improvement.

    Prasad, Sahdeo / Lall, Rajiv

    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

    2022  Volume 73, Page(s) 127023

    Abstract: Curcumin, a polyphenolic compound isolated from turmeric rhizome, displays antioxidant, anti-inflammatory, anticancer, anti-microbial, antiviral, antidiabetic, neuroprotective, immune boosting and other chemopreventive and therapeutic properties. However, ...

    Abstract Curcumin, a polyphenolic compound isolated from turmeric rhizome, displays antioxidant, anti-inflammatory, anticancer, anti-microbial, antiviral, antidiabetic, neuroprotective, immune boosting and other chemopreventive and therapeutic properties. However, the efficacy of curcumin is confined due to its aqueous insolubility, instability, low intestinal absorption, poor bioavailability, and systemic elimination. Therefore, to overcome these issues and enhance pharmacological activities of curcumin, a complex of curcumin with metals such as zinc have been synthesized. Curcumin acts as a ligand and forms a stable complex with zinc. In this review, the improved protective, and therapeutic activities of zinc-curcumin complexes are discussed. Zinc-curcumin conjugates have exhibited enhanced antioxidant, anti-inflammatory, anticancer, antimicrobial and antidiabetic properties. Zinc-curcumin complexes have also displayed hepatoprotective, gastroprotective, neuroprotective, cardioprotective and osteogenesis efficacy. These protective and therapeutic efficacies of zinc-curcumin conjugates were associated with modulation of multiple molecular mechanisms including decreased inflammatory cytokines, increased antioxidant enzymes, quenched free radicals, decreased blood glucose levels, decreased insulin resistance, induced apoptosis markers, and restored function of tumor suppressor protein p53 in cancer cells. Overall, applications of zinc-curcumin complex could be a new approach against various diseases and could also be helpful in improvement of health.
    MeSH term(s) Anti-Inflammatory Agents ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Curcumin/pharmacology ; Curcumin/therapeutic use ; Hypoglycemic Agents ; Zinc
    Chemical Substances Anti-Inflammatory Agents ; Antioxidants ; Hypoglycemic Agents ; Curcumin (IT942ZTH98) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2022-06-20
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1236267-0
    ISSN 1878-3252 ; 1611-602X ; 0946-672X
    ISSN (online) 1878-3252 ; 1611-602X
    ISSN 0946-672X
    DOI 10.1016/j.jtemb.2022.127023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2279: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Corrigendum: Commentary: Probiotic and technological properties of

    Tyagi, Amit K / Prasad, Sahdeo

    Frontiers in microbiology

    2019  Volume 10, Page(s) 1628

    Abstract: This corrects the article DOI: 10.3389/fmicb.2015.00433.]. ...

    Abstract [This corrects the article DOI: 10.3389/fmicb.2015.00433.].
    Language English
    Publishing date 2019-07-18
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2019.01628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Retraction notice to "Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells" [Life Sci. 81/17-18 (2007) 1323 - 1331].

    Prasad, Sahdeo / Kaur, Jaspreet / Roy, Preeti / Kalra, Neetu / Shukla, Yogeshwer

    Life sciences

    2022  Volume 308, Page(s) 120815

    Language English
    Publishing date 2022-08-06
    Publishing country Netherlands
    Document type Journal Article ; Retraction of Publication
    ZDB-ID 3378-9
    ISSN 1879-0631 ; 0024-3205
    ISSN (online) 1879-0631
    ISSN 0024-3205
    DOI 10.1016/j.lfs.2022.120815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.368: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Retraction Note: Chemopreventive Potential of Resveratrol in Mouse Skin Tumors Through Regulation of Mitochondrial and PI3K/AKT Signaling Pathways.

    Roy, Preeti / Kalra, Neetu / Prasad, Sahdeo / George, Jasmine / Shukla, Yogeshwer

    Pharmaceutical research

    2021  Volume 38, Issue 2, Page(s) 375

    Language English
    Publishing date 2021-02-03
    Publishing country United States
    Document type Retraction of Publication
    ZDB-ID 843063-9
    ISSN 1573-904X ; 0724-8741 ; 0739-0742
    ISSN (online) 1573-904X
    ISSN 0724-8741 ; 0739-0742
    DOI 10.1007/s11095-020-02973-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1937: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Oxidative Stress and Cancer: Chemopreventive and Therapeutic Role of Triphala.

    Prasad, Sahdeo / Srivastava, Sanjay K

    Antioxidants (Basel, Switzerland)

    2020  Volume 9, Issue 1

    Abstract: Oxidative stress, caused by the overproduction of free radicals, leads to the development of many chronic diseases including cancer. Free radicals are known to damage cellular biomolecules like lipids, proteins, and DNA that results in activation of ... ...

    Abstract Oxidative stress, caused by the overproduction of free radicals, leads to the development of many chronic diseases including cancer. Free radicals are known to damage cellular biomolecules like lipids, proteins, and DNA that results in activation of multiple signaling pathways, growth factors, transcription factors, kinases, inflammatory and cell cycle regulatory molecules. Antioxidants, which are classified as exogenous and endogenous, are responsible for the removal of free radicals and consequently the reduction in oxidative stress-mediated diseases. Diet and medicinal herbs are the major source of antioxidants. Triphala, which is a traditional Ayurvedic formulation that has been used for centuries, has been shown to have immense potential to boost antioxidant activity. It scavenges free radicals, restores antioxidant enzymes and non-enzyme levels, and decreases lipid peroxidation. In addition, Triphala is revered as a chemopreventive, chemotherapeutic, immunomodulatory, and radioprotective agent. Accumulated evidence has revealed that Triphala modulates multiple cell signaling pathways including, ERK, MAPK, NF-κB, Akt, c-Myc, VEGFR, mTOR, tubulin, p53, cyclin D1, anti-apoptotic and pro-apoptotic proteins. The present review focuses on the comprehensive appraisal of Triphala in oxidative stress and cancer.
    Language English
    Publishing date 2020-01-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox9010072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Targeting Glioblastoma Tumor Microenvironment.

    Butler, Megan / Prasad, Sahdeo / Srivastava, Sanjay K

    Advances in experimental medicine and biology

    2021  Volume 1296, Page(s) 1–9

    Abstract: Glioblastoma, also referred to as glioblastoma multiforme (GBM), is an aggressive type of brain cancer. The prognosis for GBM is poor with an average medium survival rate of 12-15 months. GBM is highly challenging to treat due to neural stem cells ... ...

    Abstract Glioblastoma, also referred to as glioblastoma multiforme (GBM), is an aggressive type of brain cancer. The prognosis for GBM is poor with an average medium survival rate of 12-15 months. GBM is highly challenging to treat due to neural stem cells phenotypic variations. These variations are determined by the tumor microenvironment (TME), which refers to all the molecules, cells, and structures that encompass and support other cells and tissues. Along with these, other vital components of the TME are fibroblasts, immune and inflammatory cells, blood and lymphatic vascular networks, extracellular matrix, and signaling molecules. This chapter provides an in-depth review of the vital components that form the TME and methods currently under development attempting to target each key area.
    MeSH term(s) Brain Neoplasms ; Glioblastoma/genetics ; Humans ; Signal Transduction ; Survival Rate ; Tumor Microenvironment
    Language English
    Publishing date 2021-06-29
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-59038-3_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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