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  1. Book ; Online: Nicholas of Cusa and the Kairos of Modernity: Cassirer, Gadamer, Blumenberg

    Edward Moore, Michael

    2013  

    Abstract: In this far-reaching essay, historian Michael Edward Moore examines modernity as an historical ... of the fifteenth-century master Nicholas of Cusa. Was Cusanus the last great medieval thinker, his ideas a summa ... to modern thought? Nicholas of Cusa lived during a time of historical and existential crisis, or kairos ...

    Abstract In this far-reaching essay, historian Michael Edward Moore examines modernity as an historical epoch following the end of the medieval period - and as a "messianic concept of time." In the early twentieth century, a debate over the meaning and origins of modernity unfolded among the philosophers Ernst Cassirer, Hans-Georg Gadamer and Hans Blumenberg. These thinkers tried to resolve the puzzle of the fifteenth-century master Nicholas of Cusa. Was Cusanus the last great medieval thinker, his ideas a summa of medieval tradition? Or was he a mysterious epochal figure, seated at one end of the bridge leading to modern thought? Nicholas of Cusa lived during a time of historical and existential crisis, or kairos, when medieval governments and cherished sources of unity were shaken. Likewise, the debate over his significance took place during a later phase of crisis for Europe, in the decades before and after the Second World War, when the collapse of European civilization was witnessed. Moore argues that modernity, so intently examined as an historical and spiritual problem, has significance for our contemporary sense of crisis
    Keywords Philosophy (General)
    Size 1 electronic resource (114 p.)
    Publisher punctum books
    Publishing place Verlagsort nicht ermittelbar
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020195658
    ISBN 9780615840550 ; 0615840558
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Promoting the use of the PRECISE score for prostate MRI during active surveillance: results from the ESOR Nicholas Gourtsoyiannis teaching fellowship.

    Giganti, Francesco / Aupin, Laurene / Thoumin, Camille / Faouzi, Ingrid / Monnier, Hippolyte / Fontaine, Matthieu / Navidi, Alexandre / Ritvo, Paul-Gydéon / Ong, Valentin / Chung, Cecile / Bibi, Imen / Lehrer, Raphaële / Hermieu, Nicolas / Barret, Eric / Ambrosi, Alessandro / Kasivisvanathan, Veeru / Emberton, Mark / Allen, Clare / Kirkham, Alex /
    Moore, Caroline M / Renard-Penna, Raphaële

    Insights into imaging

    2022  Volume 13, Issue 1, Page(s) 111

    Abstract: Objectives: The PRECISE criteria for serial multiparametric magnetic resonance imaging (MRI) of the prostate during active surveillance recommend the use of a dedicated scoring system (PRECISE score) to assess the likelihood of clinically significant ... ...

    Abstract Objectives: The PRECISE criteria for serial multiparametric magnetic resonance imaging (MRI) of the prostate during active surveillance recommend the use of a dedicated scoring system (PRECISE score) to assess the likelihood of clinically significant radiological change. This pilot study assesses the effect of an interactive teaching course on prostate MRI during active surveillance in assessing radiological change in serial imaging.
    Methods: Eleven radiology fellows and registrars with different experience in prostate MRI reading participated in a dedicated teaching course where they initially evaluated radiological change (based on their previous training in prostate MRI reading) independently in fifteen patients on active surveillance (baseline and follow-up scan), and then attended a lecture on the PRECISE score. The initial scans were reviewed for teaching purposes and afterwards the participants re-assessed the degree of radiological change in a new set of images (from fifteen different patients) applying the PRECISE score. Receiver operating characteristic analysis was performed. Confirmatory biopsies and PRECISE scores given in consensus by two radiologists (involved in the original draft of the PRECISE score) were the reference standard.
    Results: There was a significant improvement in the average area under the curve (AUC) for the assessment of radiological change from baseline (AUC: 0.60 [Confidence Intervals: 0.51-0.69] to post-teaching (AUC: 0.77 [0.70-0.84]). This was an improvement of 0.17 [0.016-0.28] (p = 0.004).
    Conclusions: A dedicated teaching course on the use of the PRECISE score improves the accuracy in the assessment of radiological change in serial MRI of the prostate.
    Language English
    Publishing date 2022-07-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2543323-4
    ISSN 1869-4101
    ISSN 1869-4101
    DOI 10.1186/s13244-022-01252-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Promoting the use of the PI-QUAL score for prostate MRI quality: results from the ESOR Nicholas Gourtsoyiannis teaching fellowship.

    Giganti, Francesco / Cole, Alexander P / Fennessy, Fiona M / Clinton, Timothy / Moreira, Pedro Lopes Da Frota / Bernardes, Mariana Costa / Westin, Carl-Fredrik / Krishnaswamy, Deepa / Fedorov, Andriy / Wollin, Daniel A / Langbein, Bjoern / Frego, Nicola / Labban, Muhieddine / Badaoui, Joy S / Chang, Steven L / Briggs, Logan G / Tokuda, Junichi / Ambrosi, Alessandro / Kirkham, Alex /
    Emberton, Mark / Kasivisvanathan, Veeru / Moore, Caroline M / Allen, Clare / Tempany, Clare M

    European radiology

    2022  Volume 33, Issue 1, Page(s) 461–471

    Abstract: Objectives: The Prostate Imaging Quality (PI-QUAL) score is a new metric to evaluate the diagnostic quality of multiparametric magnetic resonance imaging (MRI) of the prostate. This study assesses the impact of an intervention, namely a prostate MRI ... ...

    Abstract Objectives: The Prostate Imaging Quality (PI-QUAL) score is a new metric to evaluate the diagnostic quality of multiparametric magnetic resonance imaging (MRI) of the prostate. This study assesses the impact of an intervention, namely a prostate MRI quality training lecture, on the participant's ability to apply PI-QUAL.
    Methods: Sixteen participants (radiologists, urologists, physicists, and computer scientists) of varying experience in reviewing diagnostic prostate MRI all assessed the image quality of ten examinations from different vendors and machines. Then, they attended a dedicated lecture followed by a hands-on workshop on MRI quality assessment using the PI-QUAL score. Five scans assessed by the participants were evaluated in the workshop using the PI-QUAL score for teaching purposes. After the course, the same participants evaluated the image quality of a new set of ten scans applying the PI-QUAL score. Results were assessed using receiver operating characteristic analysis. The reference standard was the PI-QUAL score assessed by one of the developers of PI-QUAL.
    Results: There was a significant improvement in average area under the curve for the evaluation of image quality from baseline (0.59 [95 % confidence intervals: 0.50-0.66]) to post-teaching (0.96 [0.92-0.98]), an improvement of 0.37 [0.21-0.41] (p < 0.001).
    Conclusions: A teaching course (dedicated lecture + hands-on workshop) on PI-QUAL significantly improved the application of this scoring system to assess the quality of prostate MRI examinations.
    Key points: • A significant improvement in the application of PI-QUAL for the assessment of prostate MR image quality was observed after an educational intervention. • Appropriate training on image quality can be delivered to those involved in the acquisition and interpretation of prostate MRI. • Further investigation will be needed to understand the impact on improving the acquisition of high-quality diagnostic prostate MR examinations.
    MeSH term(s) Male ; Humans ; Prostate/diagnostic imaging ; Prostate/pathology ; Multiparametric Magnetic Resonance Imaging ; Fellowships and Scholarships ; Prostatic Neoplasms/pathology ; Magnetic Resonance Imaging/methods ; Retrospective Studies
    Language English
    Publishing date 2022-06-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-022-08947-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Nicholas of Cusa and the Kairos of Modernity

    Michael Edward Moore

    Cassirer, Gadamer, Blumenberg

    2013  

    Abstract: In this far-reaching essay, historian Michael Edward Moore examines modernity as an historical ... of the fifteenth-century master Nicholas of Cusa. Was Cusanus the last great medieval thinker, his ideas a summa ... to modern thought? Nicholas of Cusa lived during a time of historical and existential crisis, or kairos ...

    Abstract In this far-reaching essay, historian Michael Edward Moore examines modernity as an historical epoch following the end of the medieval period — and as a “messianic concept of time.” In the early twentieth century, a debate over the meaning and origins of modernity unfolded among the philosophers Ernst Cassirer, Hans-Georg Gadamer and Hans Blumenberg. These thinkers tried to resolve the puzzle of the fifteenth-century master Nicholas of Cusa. Was Cusanus the last great medieval thinker, his ideas a summa of medieval tradition? Or was he a mysterious epochal figure, seated at one end of the bridge leading to modern thought? Nicholas of Cusa lived during a time of historical and existential crisis, or kairos, when medieval governments and cherished sources of unity were shaken. Likewise, the debate over his significance took place during a later phase of crisis for Europe, in the decades before and after the Second World War, when the collapse of European civilization was witnessed. Moore argues that modernity, so intently examined as an historical and spiritual problem, has significance for our contemporary sense of crisis.
    Keywords Middle Ages ; modernity ; Nicholas of Cusa ; intellectual history ; philosophy ; HPCB
    Subject code 940
    Language English
    Publisher punctum books
    Publishing country nl
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Robinson, Nicholas

    Moore, Norman / Nutt, Claire L

    Oxford dictionary of national biography v.47

    2004  

    Author's details Norman Moore, rev. Claire L. Nutt
    MeSH term(s) Physicians ; History, 18th Century ; History of Medicine
    Keywords England
    Language English
    Size p. 389-390.
    Publisher Oxford University Press
    Publishing place Oxford ; New York
    Document type Article
    ISBN 019861411X ; 9780198614111
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article: La Crosse encephalitis virus habitat associations in Nicholas County, West Virginia.

    Nasci, R S / Moore, C G / Biggerstaff, B J / Panella, N A / Liu, H Q / Karabatsos, N / Davis, B S / Brannon, E S

    Journal of medical entomology

    2000  Volume 37, Issue 4, Page(s) 559–570

    Abstract: ... landing collections were used in a La Crosse virus-enzootic area in Nicholas County, WV. Study sites were ... in Nicholas County, WV, are contrasted with those studied in other geographic regions where La Crosse virus is ...

    Abstract Aedes triseriatus (Say) population density patterns and La Crosse encephalitis virus infection rates were evaluated in relation to a variety of habitat parameters over a 14-wk period. Ovitraps and landing collections were used in a La Crosse virus-enzootic area in Nicholas County, WV. Study sites were divided into categories by habitat type and by proximity to the residences of known La Crosse encephalitis cases. Results demonstrated that Ae. triseriatus population densities were higher in sugar maple/red maple habitats than in hemlock/mixed hardwood habitats or in a site characterized by a large number of small red maple trees. Sites containing artificial containers had higher population densities than those without. La Crosse virus minimum infection rates in mosquitoes collected as eggs ranged from 0.4/1,000 to 7.5/1,000 in the 12 study sites, but did not differ significantly among sites regardless of habitat type or proximity to human case residences. La Crosse virus infection rates in landing Ae. triseriatus mosquitoes ranged from 0.0/1,000 to 27.0/1,000. La Crosse virus was also isolated from host-seeking Ae. canadensis (Theobald) in two study sites, at rates similar to those found in the Ae. triseriatus populations. The Ae. triseriatus oviposition patterns and La Crosse virus infection rates suggest that this mosquito species disperses readily in the large woodlands of central West Virginia. The La Crosse enzootic habitats in Nicholas County, WV, are contrasted with those studied in other geographic regions where La Crosse virus is found.
    MeSH term(s) Aedes/virology ; Animals ; Behavior, Animal ; Female ; Humans ; Insect Vectors/virology ; La Crosse virus/isolation & purification ; Weather ; West Virginia
    Language English
    Publishing date 2000-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 410635-0
    ISSN 0022-2585
    ISSN 0022-2585
    DOI 10.1603/0022-2585-37.4.559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Illustrations from the Wellcome Institute Library. Nicholas Gainsford: his book.

    Moore, K

    Medical history

    1993  Volume 37, Issue 4, Page(s) 442–447

    MeSH term(s) Academies and Institutes/history ; History, 17th Century ; History, 18th Century ; History, 19th Century ; History, 20th Century ; Manuscripts as Topic/history ; United Kingdom
    Language English
    Publishing date 1993-10
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 214353-7
    ISSN 2048-8343 ; 0025-7273
    ISSN (online) 2048-8343
    ISSN 0025-7273
    DOI 10.1017/s0025727300058774
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: La crosse encephalitis virus habitat associations in Nicholas County, West Virginia

    Nasci, R.S / Moore, C.G / Biggerstaff, B.J / Panella, N.A / Liu, H.Q / Karabatsos, N / Davis, B.S / Brannon, E.S

    Journal of medical entomology. July 2000. v. 37 (4)

    2000  

    Keywords infection ; Aedes triseriatus ; Aedes canadensis ; disease vectors ; population density ; tree cavities ; deciduous forests ; botanical composition ; forest trees ; containers ; ova ; breeding sites ; West Virginia
    Language English
    Dates of publication 2000-07
    Size p. 559-570.
    Document type Article
    ZDB-ID 410635-0
    ISSN 0022-2585
    ISSN 0022-2585
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Evaluation of a Community Emergency Medicine acute oncology pathway using 28-day follow-up.

    Scott, Jamie / Moore, Nicholas

    Emergency medicine journal : EMJ

    2023  Volume 41, Issue 1, Page(s) 40–41

    MeSH term(s) Humans ; Follow-Up Studies ; Emergency Medical Services ; Research ; Emergency Medicine ; Emergency Service, Hospital
    Language English
    Publishing date 2023-12-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040124-3
    ISSN 1472-0213 ; 1472-0205
    ISSN (online) 1472-0213
    ISSN 1472-0205
    DOI 10.1136/emermed-2022-213028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Chloroquine for COVID-19 Infection.

    Moore, Nicholas

    Drug safety

    2020  Volume 43, Issue 5, Page(s) 393–394

    MeSH term(s) Betacoronavirus/drug effects ; Chloroquine/therapeutic use ; Coronavirus Infections/drug therapy ; Humans ; Pandemics ; Pneumonia, Viral/drug therapy
    Chemical Substances Chloroquine (886U3H6UFF)
    Keywords covid19
    Language English
    Publishing date 2020-04-08
    Publishing country New Zealand
    Document type Editorial
    ZDB-ID 1018059-x
    ISSN 1179-1942 ; 0114-5916
    ISSN (online) 1179-1942
    ISSN 0114-5916
    DOI 10.1007/s40264-020-00933-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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