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  1. Article: It is the time to change the paradigms of pregnant and breastfeeding women in clinical research!

    Sportiello, Liberata / Capuano, Annalisa

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1113557

    Language English
    Publishing date 2023-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1113557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Clinical prospective of SGLT2 inhibitors in atherosclerosis.

    Capuano, Annalisa / Clementi, Emilio / Paolisso, Giuseppe

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 1040649

    Language English
    Publishing date 2022-11-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.1040649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Metabolic Related Cardiomyopathy in Hyperglycemic Patients.

    Capuano, Annalisa / Clementi, Emilio / Paolisso, Giuseppe

    Frontiers in cardiovascular medicine

    2022  Volume 8, Page(s) 826914

    Language English
    Publishing date 2022-01-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2021.826914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Real-World Safety Data of the Orphan Drug Onasemnogene Abeparvovec (Zolgensma

    Ruggiero, Rosanna / Balzano, Nunzia / Nicoletti, Maria Maddalena / di Mauro, Gabriella / Fraenza, Federica / Campitiello, Maria Rosaria / Rossi, Francesco / Capuano, Annalisa

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 3

    Abstract: The recent introduction of the innovative therapy, onasemnogene abeparvovec ( ... ...

    Abstract The recent introduction of the innovative therapy, onasemnogene abeparvovec (Zolgensma
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17030394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Vaccine Hesitancy Among Religious Groups: Reasons Underlying This Phenomenon and Communication Strategies to Rebuild Trust.

    Kibongani Volet, Annie / Scavone, Cristina / Catalán-Matamoros, Daniel / Capuano, Annalisa

    Frontiers in public health

    2022  Volume 10, Page(s) 824560

    MeSH term(s) Communication ; Trust ; Vaccination ; Vaccination Hesitancy ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-02-07
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.824560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Which is the top player for the cardiovascular safety? ibrutinib vs. obinutuzumab in CLL.

    Mascolo, Annamaria / Di Napoli, Raffaella / Balzano, Nunzia / D'Alessio, Elena / Izzo, Imma / Rossi, Francesco / Paolisso, Giuseppe / Capuano, Annalisa / Sportiello, Liberata

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1229304

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-08-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1229304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Vaccine Hesitancy Among Religious Groups

    Annie Kibongani Volet / Cristina Scavone / Daniel Catalán-Matamoros / Annalisa Capuano

    Frontiers in Public Health, Vol

    Reasons Underlying This Phenomenon and Communication Strategies to Rebuild Trust

    2022  Volume 10

    Keywords vaccines ; hesitancy ; religion ; religious reasons ; communication strategies ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Cost-Effectiveness of Treatment Optimisation with Biomarkers for Immunotherapy in Solid Tumours: A Systematic Review.

    Mucherino, Sara / Lorenzoni, Valentina / Triulzi, Isotta / Del Re, Marzia / Orlando, Valentina / Capuano, Annalisa / Danesi, Romano / Turchetti, Giuseppe / Menditto, Enrica

    Cancers

    2024  Volume 16, Issue 5

    Abstract: This study investigated the health economic evaluations of predictive biomarker testing in solid tumours treated with immune checkpoint inhibitors (ICIs). Searching PubMed, EMBASE, and Web of Science from June 2010 to February 2022, 58 relevant articles ... ...

    Abstract This study investigated the health economic evaluations of predictive biomarker testing in solid tumours treated with immune checkpoint inhibitors (ICIs). Searching PubMed, EMBASE, and Web of Science from June 2010 to February 2022, 58 relevant articles were reviewed out of the 730 screened. The focus was predominantly on non-small cell lung cancer (NSCLC) (65%) and other solid tumours (40%). Among the NSCLC studies, 21 out of 35 demonstrated cost-effectiveness, notably for pembrolizumab as first-line treatment when preceded by PD-L1 assessment, cost-effective at a threshold of $100,000/QALY compared to the standard of care. However, for bladder, cervical, and triple-negative breast cancers (TNBCs), no economic evaluations met the affordability threshold of $100,000/QALY. Overall, the review highlights a certain degree of uncertainty about the cost-effectiveness of ICI. In particular, we found PD-L1 expression associated with ICI treatment to be a cost-effective strategy, particularly in NSCLC, urothelial, and renal cell carcinoma. The findings suggest the potential value of predictive biomarker testing, specifically with pembrolizumab in NSCLC, while indicating challenges in achieving cost-effectiveness for certain other solid tumours.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16050995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Editorial Expression of Concern: Hyperbaric oxygen therapy reduces the toll-like receptor signaling pathway in multiple organ failures.

    Rinaldi, Barbara / Cuzzocrea, Salvatore / Donniacuo, Maria / Capuano, Annalisa / Di Palma, Donatella / Imperatore, Francesco / Mazzon, Emanuela / Di Paola, Rosanna / Sodano, Loredana / Rossi, Francesco

    Intensive care medicine

    2024  Volume 50, Issue 3, Page(s) 491

    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Expression of Concern
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07340-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1089: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Glucagon-like Peptide-1 Receptor Agonists and Suicidal Ideation: Analysis of Real-Word Data Collected in the European Pharmacovigilance Database.

    Ruggiero, Rosanna / Mascolo, Annamaria / Spezzaferri, Angela / Carpentieri, Claudia / Torella, Daniele / Sportiello, Liberata / Rossi, Francesco / Paolisso, Giuseppe / Capuano, Annalisa

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 2

    Abstract: Background: A potential risk of suicide associated with liraglutide or semaglutide treatments has recently emerged. Therefore, we decided to investigate the reporting probability of suicidal events among glucagon-like peptide-1 receptor agonists (GLP-1 ... ...

    Abstract Background: A potential risk of suicide associated with liraglutide or semaglutide treatments has recently emerged. Therefore, we decided to investigate the reporting probability of suicidal events among glucagon-like peptide-1 receptor agonists (GLP-1 RAs).
    Methods: A retrospective pharmacovigilance study of the European Pharmacovigilance database was conducted for the period from 1 January 2018 to 10 July 2023. Disproportionality analyses (reporting odds ratio, ROR) were performed to assess the reporting probability of suicidal events among GLP-1 RAs.
    Results: A total of 230 reports of suicidal events were identified. The most reported GLP-1 RA was liraglutide (38.3%), followed by semaglutide (36.5%) and dulaglutide (16.1%). The most reported events were suicidal ideation (65.3%) and suicide attempt (19.5%). Disproportionality analysis found a higher reporting probability of suicidal events for semaglutide than dulaglutide (ROR, 2.05; 95%CI, 1.40-3.01) and exenatide (ROR, 1.81; 95%CI, 1.08-3.05). In the same way, liraglutide was associated with a higher reporting probability of suicidal events than dulaglutide (ROR, 3.98; 95%CI, 2.73-5.82) and exenatide (ROR, 3.52; 95%CI, 2.10-5.92). On the contrary, a lower reporting probability was found for semaglutide than liraglutide (ROR, 0.51; 95%CI, 0.38-0.69).
    Conclusions: Suicidal events were mostly reported with semaglutide and liraglutide, which were also associated with significantly higher reporting probabilities compared to other GLP1 RAs. Although this study provides the reporting frequencies of suicide-related events with GLP-1 RAs, establishing causality requires further investigation, which will probably be addressed by the Pharmacovigilance Risk Assessment Committee of the European Medicine Agency in the future.
    Language English
    Publishing date 2024-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17020147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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