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  1. Article ; Online: Monocyte and macrophage phenotypes: a look beyond systemic sclerosis. Response to: 'M1/M2 polarisation state of M-CSF blood-derived macrophages in systemic sclerosis' by Lescoat

    Cutolo, Maurizio / Trombetta, Amelia Chiara / Soldano, Stefano

    Annals of the rheumatic diseases

    2018  Volume 78, Issue 11, Page(s) e128

    MeSH term(s) Humans ; Macrophage Colony-Stimulating Factor ; Macrophages ; Monocytes ; Phenotype ; Scleroderma, Systemic
    Chemical Substances Macrophage Colony-Stimulating Factor (81627-83-0)
    Language English
    Publishing date 2018-09-29
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2018-214371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.114: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 167: Show issues

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  2. Book ; Conference proceedings: Effect of the diet and the climate in rheumatic and musculoskeletal diseases

    Cutolo, M.

    XVII Mediterranean Congress of Rheumatology : 12-14 april 2018 Genova, Italy

    (Clinical and experimental rheumatology. Suppl. ; 109 (2018))

    2018  

    Event/congress Mediterranean Congress of Rheumatology (17., 2018, Genua)
    Author's details congress chairperson M. Cutolo
    Series title Clinical and experimental rheumatology. Suppl. ; 109 (2018)
    Clinical and experimental rheumatology
    Collection Clinical and experimental rheumatology
    Language English
    Size S-111 Seiten, Illustrationen
    Publisher Clinical and Experimental Rheumatology S.A.S
    Publishing place Pisa
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT019727587
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 2002 -Suppl.109- not available for loan Zeitschriften-Lesesaal

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  3. Article ; Online: The Importance of Neuroendocrine Immunology Pathways in the Course of COVID-19.

    Cutolo, Maurizio / Gotelli, Emanuele

    Neuroimmunomodulation

    2024  Volume 31, Issue 1, Page(s) 62–64

    MeSH term(s) Humans ; COVID-19/immunology ; Neurosecretory Systems/immunology ; Neuroimmunomodulation/immunology ; Neuroimmunomodulation/physiology ; SARS-CoV-2/immunology
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 1184368-8
    ISSN 1423-0216 ; 1021-7401
    ISSN (online) 1423-0216
    ISSN 1021-7401
    DOI 10.1159/000536661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3975: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Complex role of oestrogens in the risk and severity of rheumatoid arthritis in menopause.

    Cutolo, Maurizio / Gotelli, Emanuele

    RMD open

    2023  Volume 9, Issue 2

    MeSH term(s) Female ; Humans ; Arthritis, Rheumatoid/epidemiology ; Arthritis, Rheumatoid/etiology ; Menopause ; Estrogens
    Chemical Substances Estrogens
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Editorial
    ZDB-ID 2812592-7
    ISSN 2056-5933 ; 2056-5933
    ISSN (online) 2056-5933
    ISSN 2056-5933
    DOI 10.1136/rmdopen-2023-003176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The 2023's Growing Evidence Confirming the Relationship between Vitamin D and Autoimmune Diseases.

    Cutolo, Maurizio / Gotelli, Emanuele

    Nutrients

    2023  Volume 15, Issue 22

    Abstract: The second Special Issue of Nutrients dedicated to "Vitamin D, Immune Response, and Autoimmune Diseases" will include original data and recent achievements from authors who would like to participate in this research topic [ ... ]. ...

    Abstract The second Special Issue of Nutrients dedicated to "Vitamin D, Immune Response, and Autoimmune Diseases" will include original data and recent achievements from authors who would like to participate in this research topic [...].
    MeSH term(s) Humans ; Vitamin D/physiology ; Autoimmune Diseases ; Vitamins ; Vitamin D Deficiency/complications
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins
    Language English
    Publishing date 2023-11-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15224760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Clinical Promise of Microalgae in Rheumatoid Arthritis: From Natural Compounds to Recombinant Therapeutics.

    Cutolo, Edoardo Andrea / Caferri, Roberto / Campitiello, Rosanna / Cutolo, Maurizio

    Marine drugs

    2023  Volume 21, Issue 12

    Abstract: Rheumatoid arthritis (RA) is an invalidating chronic autoimmune disorder characterized by joint inflammation and progressive bone damage. Dietary intervention is an important component in the treatment of RA to mitigate oxidative stress, a major ... ...

    Abstract Rheumatoid arthritis (RA) is an invalidating chronic autoimmune disorder characterized by joint inflammation and progressive bone damage. Dietary intervention is an important component in the treatment of RA to mitigate oxidative stress, a major pathogenic driver of the disease. Alongside traditional sources of antioxidants, microalgae-a diverse group of photosynthetic prokaryotes and eukaryotes-are emerging as anti-inflammatory and immunomodulatory food supplements. Several species accumulate therapeutic metabolites-mainly lipids and pigments-which interfere in the pro-inflammatory pathways involved in RA and other chronic inflammatory conditions. The advancement of the clinical uses of microalgae requires the continuous exploration of phytoplankton biodiversity and chemodiversity, followed by the domestication of wild strains into reliable producers of said metabolites. In addition, the tractability of microalgal genomes offers unprecedented possibilities to establish photosynthetic microbes as light-driven biofactories of heterologous immunotherapeutics. Here, we review the evidence-based anti-inflammatory mechanisms of microalgal metabolites and provide a detailed coverage of the genetic engineering strategies to enhance the yields of endogenous compounds and to develop innovative bioproducts.
    MeSH term(s) Humans ; Microalgae/metabolism ; Arthritis, Rheumatoid/drug therapy ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Antioxidants/metabolism ; Dietary Supplements ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/metabolism
    Chemical Substances Antioxidants ; Anti-Inflammatory Agents
    Language English
    Publishing date 2023-12-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md21120630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Circadian rhythms and rheumatoid arthritis.

    Cutolo, Maurizio

    Joint bone spine

    2018  Volume 86, Issue 3, Page(s) 327–333

    Abstract: Circadian rhythms (Nobel prize for Medicine 2017) regulate, under action of biological clocks located both at the level of central nervous system and inside peripheral cells, several daily activities, embracing sleep, feeding times, energy metabolism, ... ...

    Abstract Circadian rhythms (Nobel prize for Medicine 2017) regulate, under action of biological clocks located both at the level of central nervous system and inside peripheral cells, several daily activities, embracing sleep, feeding times, energy metabolism, endocrine and immune functions with related pathological conditions, including rheumatoid arthritis (RA). In RA the circadian rhythms impact on cellular functions, involving night synthesis and release of pro-inflammatory cytokines and chemokines, cell migration to inflamed tissues, phagocytosis, proliferative cell response and all are peaking at late night. In chronic inflammatory conditions such as RA, the amplitude of the circadian rhythm of the anti-inflammatory endogenous cortisol availability is not increased as expected and requested, which indicate a reduced night cortisol secretion under the adrenal chronic stress induced by the disease. Therefore, the prevention/treatment of the immune cell night hyperactivity, with related flare of cytokine synthesis and morning RA clinical symptoms, has been shown more effective when the availability of the exogenous glucocorticoids is obtained in the middle of the night (night release). The impressive positive results observed in RA patients treated with modified-night release prednisone with a low-dose chronotherapy, seem applicable even for other agents such as conventional NSAIDs and DMARDs, including the positive experimental and clinical results obtained by the night time daily administration of methotrexate. Interestingly, a very recent study showed that methotrexate upregulates important cell circadian genes, resulting in induction of apoptosis in synovial fibroblasts. The link between the circadian rhythms of the disease and the chronotherapy of RA is promising.
    MeSH term(s) Aged ; Anti-Inflammatory Agents/administration & dosage ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/physiopathology ; Circadian Rhythm/drug effects ; Drug Chronotherapy ; Female ; Glucocorticoids/administration & dosage ; Humans ; Male ; Middle Aged ; Prognosis ; Risk Assessment ; Severity of Illness Index ; Treatment Outcome
    Chemical Substances Anti-Inflammatory Agents ; Antirheumatic Agents ; Glucocorticoids
    Language English
    Publishing date 2018-09-15
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2020487-5
    ISSN 1778-7254 ; 1297-319X
    ISSN (online) 1778-7254
    ISSN 1297-319X
    DOI 10.1016/j.jbspin.2018.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4590: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Emerging nailfold capillaroscopic patterns in COVID-19: from acute patients to survivors.

    Cutolo, M / Sulli, A / Smith, V / Gotelli, E

    Reumatismo

    2023  Volume 74, Issue 4

    Abstract: The SARS-CoV-2 infection causing the Coronavirus disease-19 (COVID-19) is characterized by a broad range of clinical manifestations, implicating microvascular damage with endothelial dysfunction and different organ involvement. ...

    Abstract The SARS-CoV-2 infection causing the Coronavirus disease-19 (COVID-19) is characterized by a broad range of clinical manifestations, implicating microvascular damage with endothelial dysfunction and different organ involvement.
    MeSH term(s) Humans ; Nails/blood supply ; COVID-19 ; Capillaries ; SARS-CoV-2 ; Survivors
    Language English
    Publishing date 2023-03-21
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 414816-2
    ISSN 2240-2683 ; 0048-7449
    ISSN (online) 2240-2683
    ISSN 0048-7449
    DOI 10.4081/reumatismo.2022.1555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 392: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 654: Show issues

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  9. Article ; Online: Nutrition and Diet in Rheumatoid Arthritis.

    Cutolo, Maurizio / Nikiphorou, Elena

    Nutrients

    2022  Volume 14, Issue 4

    Abstract: Rheumatic and musculoskeletal diseases (RMDs) are chronic systemic immune/inflammatory conditions characterized by the interaction between gene predisposition, autoimmunity and environmental factors [ ... ]. ...

    Abstract Rheumatic and musculoskeletal diseases (RMDs) are chronic systemic immune/inflammatory conditions characterized by the interaction between gene predisposition, autoimmunity and environmental factors [...].
    MeSH term(s) Arthritis, Rheumatoid/etiology ; Autoimmunity ; Diet ; Humans ; Musculoskeletal Diseases ; Nutritional Status ; Rheumatic Diseases
    Language English
    Publishing date 2022-02-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14040888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Nutrition and Diet in Rheumatoid Arthritis

    Cutolo, Maurizio / Nikiphorou, Elena

    Nutrients. 2022 Feb. 19, v. 14, no. 4

    2022  

    Abstract: Rheumatic and musculoskeletal diseases (RMDs) are chronic systemic immune/inflammatory conditions characterized by the interaction between gene predisposition, autoimmunity and environmental factors [ ... ] ...

    Abstract Rheumatic and musculoskeletal diseases (RMDs) are chronic systemic immune/inflammatory conditions characterized by the interaction between gene predisposition, autoimmunity and environmental factors [...]
    Keywords autoimmunity ; diet ; genes ; musculoskeletal system ; rheumatoid arthritis
    Language English
    Dates of publication 2022-0219
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14040888
    Database NAL-Catalogue (AGRICOLA)

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