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  1. Article ; Online: Experimental and computational study of the beta shielding properties of polycarbonate filled with lead nitrate.

    Chandrappa Koramar, Manjappa / Lobo, Blaise

    Radiation protection dosimetry

    2023  Volume 199, Issue 11, Page(s) 1248–1255

    Abstract: The mass attenuation coefficient of lead nitrate (Pb(NO3)2)-filled polycarbonate (PC) composite films were determined both computationally (using Baltakmen's and Thummel empirical formulae) and experimentally using 204Tl and 90Sr-90Y radio-isotopes for ... ...

    Abstract The mass attenuation coefficient of lead nitrate (Pb(NO3)2)-filled polycarbonate (PC) composite films were determined both computationally (using Baltakmen's and Thummel empirical formulae) and experimentally using 204Tl and 90Sr-90Y radio-isotopes for films at different filler levels 0, 5, 15, 25, 35 and 50 weight percent (Wt.%). In comparison with Thummel empirical formula, the values obtained from Baltakmen's empirical formula is in good agreement with the experiment. The percentage decrease of half value layer values were (52 ± 8) and (60 ± 10)% for 204Tl and 90Sr-90Y, on comparing the values for 0 and 50 Wt.% films, and so the prepared composite films shield the beta particles effectively. The PC that used to shield the low-energy beta particles of 90Sr-90Y can also moderate the higher energy beta particles; the plot of end point energy of 90Sr-90Y versus thickness of PC exhibits a decreasing trend, which confirms that PC acts as an electron moderator.
    MeSH term(s) Yttrium Radioisotopes ; Strontium Radioisotopes ; Lead ; Beta Particles
    Chemical Substances Yttrium-90 (1K8M7UR6O1) ; Yttrium Radioisotopes ; Strontium-90 (5TZZ77Z4ER) ; Strontium Radioisotopes ; lead nitrate (6E5P1699FI) ; Lead (2P299V784P) ; polycarbonate (25766-59-0)
    Language English
    Publishing date 2023-06-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncad171
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  2. Article: Prevalence of fall and associated risk factors among the elderly living in a rural area of Kolar.

    Bhoomika, Venkateshappa / Chandrappa, Muninarayana / Reddy, Mahendra M

    Journal of family medicine and primary care

    2022  Volume 11, Issue 7, Page(s) 3956–3960

    Abstract: Background: Falls in elderly persons are one of the leading causes of death. Falls are responsible for 10-15% of all emergency department visits among elderly. The study was conducted to determine the prevalence of falls in rural areas and to assess the ...

    Abstract Background: Falls in elderly persons are one of the leading causes of death. Falls are responsible for 10-15% of all emergency department visits among elderly. The study was conducted to determine the prevalence of falls in rural areas and to assess the various socio-demographic factors associated with falls.
    Methodology: It was a community-based, cross-sectional study conducted in Rural Health Training Centre (RHTC), Devarayanasamudra, Department of Community Medicine, among the elderly persons aged ≥ 60 years. The total sample size was 511, calculated using a previous study using OpenEpi software. The data were collected using a pretested semi-structured questionnaire. The period prevalence of falls was assessed by asking for history of falls in the past 12 months. Chi-square and regression analysis were performed with statistically significant
    Results: Out of 511 elderly persons aged ≥60 years, females accounted for about 54.8% and most of them were of 60-69 years age-group. The majority of the study subjects were illiterates (77.3%), and most of them were married (77.2%). The prevalence of falls in elderly persons was 46.8%. The elderly aged ≥70 years, females, chronic diseases, and use of walking aid were observed to have a statistically significant association with falls (p < 0.005).
    Conclusion: Elderly falls are very common. The primary healthcare providers in rural areas play an important role in prevention of falls in elderly. Caregivers, along with elderly, should be given more detailed health education related to fall prevention.
    Language English
    Publishing date 2022-07-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_1580_21
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  3. Book ; Online: A level-set formulation to simulate diffusive solid/solid phase transformation in polycrystalline metallic materials -- Application to austenite decomposition in steels

    Chandrappa, Nitish / Bernacki, Marc

    2022  

    Abstract: Numerous full-field numerical methods exist concerning the digital description of polycrystalline materials and the modeling of their evolution during thermomechanical treatments. However, these strategies are globally dedicated to the modeling of ... ...

    Abstract Numerous full-field numerical methods exist concerning the digital description of polycrystalline materials and the modeling of their evolution during thermomechanical treatments. However, these strategies are globally dedicated to the modeling of recrystallization and grain growth for single-phase materials, or to the modeling of phase transformations without considering recrystallization and related phenomena. A generalized numerical framework capable of making predictions in a multi-phase polycrystalline context while respecting the concomitance of the different microstructural mechanisms is thus of prime interest. A novel finite element level-set based full-field numerical formulation is proposed to principally simulate diffusive solid-solid phase transformation at the mesoscopic scale in the context of two-phase metallic alloys. A global kinetic framework, capable of accounting for other concomitant mechanisms such as recrystallization and grain growth is considered in this numerical model. The proposed numerical framework is shown to be promising through a couple of illustrative 1D and 2D test cases in the context of austenite decomposition in steels and compared with ThermoCalc estimations.
    Keywords Computer Science - Computational Engineering ; Finance ; and Science ; Condensed Matter - Materials Science
    Subject code 669
    Publishing date 2022-08-19
    Publishing country us
    Document type Book ; Online
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  4. Article: Estimation of Fluoride and Sirtuin1 in Patients with Diabetic Nephropathy in Kolar District of Karnataka, India.

    Ram Mohan, Sai Deepika / Shashidhar, Kurpad N / Anjanappa, Raveesha / Chandrappa, Muninarayana

    Journal of laboratory physicians

    2021  Volume 14, Issue 1, Page(s) 57–64

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2021-08-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727
    ISSN (online) 0974-7826
    ISSN 0974-2727
    DOI 10.1055/s-0041-1732817
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  5. Article: Rare complication of doxorubicin-induced complete heart block in a patient with Hodgkin's lymphoma: a case report.

    Mahadevappa, Manjappa / Pura Krishnamurthy, Kiran / Attri, Lakshay Kumar / Chandrappa, Yogitha / Kulkarni, Prashanth

    European journal of hospital pharmacy : science and practice

    2022  Volume 30, Issue 5, Page(s) e26

    Abstract: Anthracyclines are associated with cardiotoxic manifestations that are mainly dose-dependent, with onset varying from a few days to many years after stopping treatment. Frequent monitoring for toxic manifestations, early detection, cessation of ... ...

    Abstract Anthracyclines are associated with cardiotoxic manifestations that are mainly dose-dependent, with onset varying from a few days to many years after stopping treatment. Frequent monitoring for toxic manifestations, early detection, cessation of anthracycline use and appropriate treatment is the key to preventing morbidity and mortality. Complete heart block with doxorubicin use in Hodgkin's lymphoma is rarely reported, and is a severe toxic manifestation necessitating withdrawal or changing of regimen to etoposide + bleomycin + vinblastine + dacarbazine (EBVD), as in this case.
    MeSH term(s) Humans ; Hodgkin Disease/drug therapy ; Doxorubicin/adverse effects ; Anthracyclines ; Dacarbazine/adverse effects ; Polyketides ; Heart Block
    Chemical Substances Doxorubicin (80168379AG) ; Anthracyclines ; Dacarbazine (7GR28W0FJI) ; Polyketides
    Language English
    Publishing date 2022-09-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2650179-X
    ISSN 2047-9964 ; 2047-9956
    ISSN (online) 2047-9964
    ISSN 2047-9956
    DOI 10.1136/ejhpharm-2022-003417
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  6. Article ; Online: Catalyst- and Additive-Free Methodical Ring Expansion Protocol to Access Benzooxepino-Fused Pyrroles.

    Karunakar, Galla V / Sunil, Komalla / Bharath Kumar, Perla / Chandrappa, Muneppa / Guduru, Ravinder / Kantevari, Srinivas / Sridhar, Balasubramanian

    Chemistry, an Asian journal

    2023  Volume 18, Issue 4, Page(s) e202201071

    Abstract: An efficient metal-free, additive-free synthetic method was developed to access benzooxepino-fused pyrrole derivatives from alkynyl substituted aziridines. In this organic transformation, two new C-C bonds were formed via initial cleavage of C-C bond of ... ...

    Abstract An efficient metal-free, additive-free synthetic method was developed to access benzooxepino-fused pyrrole derivatives from alkynyl substituted aziridines. In this organic transformation, two new C-C bonds were formed via initial cleavage of C-C bond of aziridine ring by in situ generated azomethine ylides. Moderate to excellent yields of benzooxepino-fused pyrroles were obtained atom economically in the presence of t-BuOH in one-pot.
    Language English
    Publishing date 2023-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202201071
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  7. Article: Nanomaterial assisted bulk scale synthesis of 2-methyl-6-nitroquinoline.

    Chandrappa, M / Swathi, Korrapati / Girish Kumar, S / Pullela, Phani Kumar

    Materials today. Proceedings

    2020  Volume 37, Page(s) 1469–1474

    Abstract: Quinolines are an interesting class of moieties with various medicinal chemistry uses. The most prominent is their ability to be used as the last line of therapy for bacterial and viral infections including recent COVID-19. The synthesis of quinoline is ... ...

    Abstract Quinolines are an interesting class of moieties with various medicinal chemistry uses. The most prominent is their ability to be used as the last line of therapy for bacterial and viral infections including recent COVID-19. The synthesis of quinoline is through a cyclization reaction and overall reaction yields are about 20%. The bulky ring and the associated crowding of functional groups limit the catalyst options. In this publication, the use of Fe
    Keywords covid19
    Language English
    Publishing date 2020-08-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2797693-2
    ISSN 2214-7853
    ISSN 2214-7853
    DOI 10.1016/j.matpr.2020.07.103
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  8. Article ; Online: Iontophoretic delivery of methotrexate in the treatment of palmar psoriasis: A randomised controlled study.

    Andanooru Chandrappa, Naveen Kumar / Channakeshavaiah Ravikumar, Banavase / Rangegowda, Suresh Mahadevarahalli

    The Australasian journal of dermatology

    2020  Volume 61, Issue 2, Page(s) 140–146

    Abstract: ... of palmar psoriasis was assessed by modified Palmoplantar Pustular Psoriasis Area and Severity Index (m ...

    Abstract Background/objectives: Palmoplantar psoriasis is a localised variant of psoriasis. Topical therapy is the preferred treatment modality, but in severe and recalcitrant cases, systemic drugs like methotrexate are prescribed, with potential for significant adverse effects. Iontophoresis is gaining popularity in enhancing the transdermal delivery of drugs in ionic state. This study was undertaken to evaluate and compare the efficacy of topical methotrexate by iontophoresis technique with clobetasol propionate 0.05% ointment in the treatment of palmar psoriasis.
    Methods: This was a prospective randomised controlled study conducted on patients with palmar psoriasis. Group 1 patients (n = 31) were treated with once weekly iontophoretic delivery of methotrexate over 6 sittings, and group 2 patients (n = 31) were treated with clobetasol propionate 0.05% ointment, twice daily for 6 weeks. Severity of palmar psoriasis was assessed by modified Palmoplantar Pustular Psoriasis Area and Severity Index (m-PPPASI), and treatment was considered as satisfactory when there was >50% improvement.
    Results: Sixty two patients were recruited, of which 50 completed the study. Eight out of 25 (32%) patients in group 1 and 12 out of 25 (48%) patients in group 2 showed satisfactory improvement at the end of 6 weeks. However, this difference was statistically not significant (P = 0.25). Burn injury was noted in 12 (48%) group 1 patients with no adverse effects in group 2.
    Conclusion: Iontophoretic delivery of methotrexate is a promising therapeutic modality, the efficacy of which is comparable to that of clobetasol propionate ointment in the treatment of palmar psoriasis.
    MeSH term(s) Administration, Cutaneous ; Adult ; Anti-Inflammatory Agents/therapeutic use ; Calcitriol/therapeutic use ; Female ; Humans ; Keratolytic Agents/therapeutic use ; Male ; Methotrexate/therapeutic use ; Middle Aged ; Prospective Studies ; Psoriasis/drug therapy ; Severity of Illness Index ; Treatment Outcome
    Chemical Substances Anti-Inflammatory Agents ; Keratolytic Agents ; Calcitriol (FXC9231JVH) ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2020-01-16
    Publishing country Australia
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.13228
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    In stock of ZB MED Cologne/Königswinter

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  9. Article ; Online: Development of mental health services for lower-skilled migrant workers in Qatar.

    Latoo, Javed / Wadoo, Ovais / Iqbal, Yousaf / Chandrappa, Nirvana Swamy Kudlur / Tulley, Iain / Alabdulla, Majid

    Asian journal of psychiatry

    2021  Volume 62, Page(s) 102709

    Abstract: The largest group of migrants in Gulf Cooperation Council (GCC) countries are lower-skilled migrant workers. GCC countries have witnessed significant healthcare infrastructure investments over recent decades. Despite this, they are lagging to mainstream ... ...

    Abstract The largest group of migrants in Gulf Cooperation Council (GCC) countries are lower-skilled migrant workers. GCC countries have witnessed significant healthcare infrastructure investments over recent decades. Despite this, they are lagging to mainstream the mental health needs of lower-skilled migrants into national health policy frameworks. Qatar is one of the GCC countries where lower-skilled migrants constitute 50 per cent of population. In this article,we provide an overview of the development of specialist mental health service for lower-skilled migrants' and discuss the challenges, and measures taken by the State of Qatar to mainstream their health needs into national health policy framework.
    MeSH term(s) Humans ; Mental Health ; Mental Health Services ; Qatar ; Transients and Migrants
    Language English
    Publishing date 2021-05-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2021.102709
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  10. Article ; Online: cgSSR marker-based genome-wide association study identified genomic regions for panicle characters and yield in rice (Oryza sativa L.).

    Sah, Rameswar Prasad / Nayak, Amrit Kumar / Chandrappa, Anilkumar / Behera, Sasmita / Azharudheen Tp, Muhammed / Lavanya, G Roopa

    Journal of the science of food and agriculture

    2022  Volume 103, Issue 2, Page(s) 720–728

    Abstract: Background: To improve production efficiency, positive alleles corresponding to yield-related attributes must be accumulated in a single elite background. We designed and used cgSSR markers, which are superior to random SSR markers in genome-wide ... ...

    Abstract Background: To improve production efficiency, positive alleles corresponding to yield-related attributes must be accumulated in a single elite background. We designed and used cgSSR markers, which are superior to random SSR markers in genome-wide association study, to identify genomic regions that contribute to panicle characters and grain yield in this study.
    Results: As evidenced by the high polymorphic information content value and gene diversity coefficient, the new cgSSR markers were determined to be highly informative. These cgSSR markers were employed to generate genotype data for an association panel evaluated for four panicle characters and grain yield over three seasons. For five traits, 17 significant marker-trait associations on six chromosomes were discovered. The percentage of phenotypic variance that could be explained ranged from 4% to 13%. Unrelated gene-derived markers had a strong association with target traits as well.
    Conclusion: Trait-associated cgSSR markers derived from corresponding or related genes ensure their utility in direct allele selection, while other linked markers aid in allele selection indirectly by altering the phenotype of interest. Through a marker-assisted breeding approach, these marker-trait associations can be leveraged to accumulate favourable alleles for yield enhancement in rice. © 2022 Society of Chemical Industry.
    MeSH term(s) Oryza/genetics ; Genome-Wide Association Study ; Quantitative Trait Loci ; Plant Breeding ; Phenotype ; Edible Grain/genetics ; Genetic Markers ; Genomics ; Genotype
    Chemical Substances Genetic Markers
    Language English
    Publishing date 2022-09-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.12183
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