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  1. Article ; Online: Cones and spirals: Multi-axis acquisition for scalar and vector electron tomography.

    Lewis, George R / Ringe, Emilie / Midgley, Paul A

    Ultramicroscopy

    2023  Volume 252, Page(s) 113775

    Abstract: Electron tomography (ET) has become an important tool for understanding the 3D nature of nanomaterials, with recent developments enabling not only scalar reconstructions of electron density, but also vector reconstructions of magnetic fields. However, ... ...

    Abstract Electron tomography (ET) has become an important tool for understanding the 3D nature of nanomaterials, with recent developments enabling not only scalar reconstructions of electron density, but also vector reconstructions of magnetic fields. However, whilst new signals have been incorporated into the ET toolkit, the acquisition schemes have largely kept to conventional single-axis tilt series for scalar ET, and dual-axis schemes for magnetic vector ET. In this work, we explore the potential of using multi-axis tilt schemes including conical and spiral tilt schemes to improve reconstruction fidelity in scalar and magnetic vector ET. Through a combination of systematic simulations and a proof-of-concept experiment, we show that spiral and conical tilt schemes have the potential to produce substantially improved reconstructions, laying the foundations of a new approach to electron tomography acquisition and reconstruction.
    MeSH term(s) Electron Microscope Tomography/methods ; Image Processing, Computer-Assisted/methods ; Magnetic Fields
    Language English
    Publishing date 2023-06-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1479043-9
    ISSN 1879-2723 ; 0304-3991
    ISSN (online) 1879-2723
    ISSN 0304-3991
    DOI 10.1016/j.ultramic.2023.113775
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: WRAP: A wavelet-regularised reconstruction algorithm for magnetic vector electron tomography.

    Lewis, George R / Wolf, Daniel / Lubk, Axel / Ringe, Emilie / Midgley, Paul A

    Ultramicroscopy

    2023  Volume 253, Page(s) 113804

    Abstract: Magnetic vector electron tomography (VET) is a promising technique that enables better understanding of micro- and nano-magnetic phenomena through the reconstruction of 3D magnetic fields at high spatial resolution. Here we introduce WRAP (Wavelet ... ...

    Abstract Magnetic vector electron tomography (VET) is a promising technique that enables better understanding of micro- and nano-magnetic phenomena through the reconstruction of 3D magnetic fields at high spatial resolution. Here we introduce WRAP (Wavelet Regularised A Program), a reconstruction algorithm for magnetic VET that directly reconstructs the magnetic vector potential A using a compressed sensing framework which regularises for sparsity in the wavelet domain. We demonstrate that using WRAP leads to a significant increase in the fidelity of the 3D reconstruction and is especially robust when dealing with very limited data; using datasets simulated with realistic noise, we compare WRAP to a conventional reconstruction algorithm and find an improvement of ca. 60% when averaged over several performance metrics. Moreover, we further validate WRAP's performance on experimental electron holography data, revealing the detailed magnetism of vortex states in a CuCo nanowire. We believe WRAP represents a major step forward in the development of magnetic VET as a tool for probing magnetism at the nanoscale.
    Language English
    Publishing date 2023-07-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1479043-9
    ISSN 1879-2723 ; 0304-3991
    ISSN (online) 1879-2723
    ISSN 0304-3991
    DOI 10.1016/j.ultramic.2023.113804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Paul Tillich's new science of values

    Midgley, Louis C / Tillich, Paul

    The Western political quarterly : official journal of Western Political Science Association Vol. 15, No. 2 , p. 235-253

    1962  Volume 15, Issue 2, Page(s) 235–253

    Author's details Louis C. Midgley
    Publisher Univ.
    Publishing place Salt Lake City, Utah
    Document type Article
    ZDB-ID 207524-6
    Database ECONomics Information System

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  4. Article ; Online: Progress and opportunities in EELS and EDS tomography.

    Collins, Sean M / Midgley, Paul A

    Ultramicroscopy

    2017  Volume 180, Page(s) 133–141

    Abstract: Electron tomography using energy loss and X-ray spectroscopy in the electron microscope continues to develop in rapidly evolving and diverse directions, enabling new insight into the three-dimensional chemistry and physics of nanoscale volumes. Progress ... ...

    Abstract Electron tomography using energy loss and X-ray spectroscopy in the electron microscope continues to develop in rapidly evolving and diverse directions, enabling new insight into the three-dimensional chemistry and physics of nanoscale volumes. Progress has been made recently in improving reconstructions from EELS and EDS signals in electron tomography by applying compressed sensing methods, characterizing new detector technologies in detail, deriving improved models of signal generation, and exploring machine learning approaches to signal processing. These disparate threads can be brought together in a cohesive framework in terms of a model-based approach to analytical electron tomography. Models incorporate information on signal generation and detection as well as prior knowledge of structures in the spectrum image data. Many recent examples illustrate the flexibility of this approach and its feasibility for addressing challenges in non-linear or limited signals in EELS and EDS tomography. Further work in combining multiple imaging and spectroscopy modalities, developing synergistic data acquisition, processing, and reconstruction approaches, and improving the precision of quantitative spectroscopic tomography will expand the frontiers of spatial resolution, dose limits, and maximal information recovery.
    Language English
    Publishing date 2017
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1479043-9
    ISSN 1879-2723 ; 0304-3991
    ISSN (online) 1879-2723
    ISSN 0304-3991
    DOI 10.1016/j.ultramic.2017.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Materials science. Electronic bonding revealed by electron diffraction.

    Midgley, Paul A

    Science (New York, N.Y.)

    2011  Volume 331, Issue 6024, Page(s) 1528–1529

    Language English
    Publishing date 2011-03-25
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.1203614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Unveiling the Interaction Mechanisms of Electron and X-ray Radiation with Halide Perovskite Semiconductors using Scanning Nanoprobe Diffraction.

    Ferrer Orri, Jordi / Doherty, Tiarnan A S / Johnstone, Duncan / Collins, Sean M / Simons, Hugh / Midgley, Paul A / Ducati, Caterina / Stranks, Samuel D

    Advanced materials (Deerfield Beach, Fla.)

    2022  Volume 34, Issue 18, Page(s) e2200383

    Abstract: The interaction of high-energy electrons and X-ray photons with beam-sensitive semiconductors such as halide perovskites is essential for the characterization and understanding of these optoelectronic materials. Using nanoprobe diffraction techniques, ... ...

    Abstract The interaction of high-energy electrons and X-ray photons with beam-sensitive semiconductors such as halide perovskites is essential for the characterization and understanding of these optoelectronic materials. Using nanoprobe diffraction techniques, which can investigate physical properties on the nanoscale, studies of the interaction of electron and X-ray radiation with state-of-the-art (FA
    Language English
    Publishing date 2022-03-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202200383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Associations between baseline cortisol and trajectory of symptom improvement in depressed adolescents receiving psychological therapy.

    Chadha, Ankit / Neufeld, Sharon / Goodyer, Ian Michael / Fonagy, Peter / Midgley, Nick / Wilkinson, Paul Oliver

    Journal of affective disorders

    2021  Volume 287, Page(s) 191–195

    Abstract: Background: Cortisol hypersecretion in depressed adolescents and adults is associated with more persistent illness and may signal a lower response to psychological therapies. A meta-analysis of small and heterogenous studies demonstrated that higher pre- ...

    Abstract Background: Cortisol hypersecretion in depressed adolescents and adults is associated with more persistent illness and may signal a lower response to psychological therapies. A meta-analysis of small and heterogenous studies demonstrated that higher pre-treatment basal cortisol levels were associated with poorer response specifically to psychological therapy for depression. The objective of this study was to investigate the relationship between both morning and evening salivary cortisol levels and response to psychological therapy in depressed adolescents participating in one large randomised controlled trial.
    Methods: We tested the association between morning and evening salivary cortisol levels at baseline and improvement in depressive symptoms in response to psychological therapies in depressed adolescents at 6 time points: baseline, 6, 12, 36, 52- and 86-weeks post-randomisation, using the self-reported Mood and Feelings Questionnaire (MFQ).
    Results: High evening cortisol was associated with a slower initial decline in depressive symptoms (cortisol x quadratic time p = .022); however it was not associated with total change in depressive symtoms over the whole course of the study. Morning cortisol was not associated with change in depressive symptoms. These effects were not significantly different across the three psychological therapies.
    Limitations: Results may not generalize to adolescents receiving other treatments (medication) or no treatment, and may not generalize to adults. Only a minority of eligible participants collected valid cortisol samples.
    Conclusions: Higher pretreatment evening cortisol may impair a depressed adolescent's ability to use psychological therapy.
    MeSH term(s) Adolescent ; Adult ; Depression/therapy ; Humans ; Hydrocortisone ; Randomized Controlled Trials as Topic ; Saliva ; Self Report
    Chemical Substances Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2021-03-23
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2021.03.046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Mapping nanoscale carrier confinement in polycrystalline graphene by terahertz spectroscopy.

    Whelan, Patrick R / De Fazio, Domenico / Pasternak, Iwona / Thomsen, Joachim D / Zelzer, Steffen / Mikkelsen, Martin O / Booth, Timothy J / Diekhöner, Lars / Sassi, Ugo / Johnstone, Duncan / Midgley, Paul A / Strupinski, Wlodek / Jepsen, Peter U / Ferrari, Andrea C / Bøggild, Peter

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 3163

    Abstract: Terahertz time-domain spectroscopy (THz-TDS) can be used to map spatial variations in electrical properties such as sheet conductivity, carrier density, and carrier mobility in graphene. Here, we consider wafer-scale graphene grown on germanium by ... ...

    Abstract Terahertz time-domain spectroscopy (THz-TDS) can be used to map spatial variations in electrical properties such as sheet conductivity, carrier density, and carrier mobility in graphene. Here, we consider wafer-scale graphene grown on germanium by chemical vapor deposition with non-uniformities and small domains due to reconstructions of the substrate during growth. The THz conductivity spectrum matches the predictions of the phenomenological Drude-Smith model for conductors with non-isotropic scattering caused by backscattering from boundaries and line defects. We compare the charge carrier mean free path determined by THz-TDS with the average defect distance assessed by Raman spectroscopy, and the grain boundary dimensions as determined by transmission electron microscopy. The results indicate that even small angle orientation variations below 5° within graphene grains influence the scattering behavior, consistent with significant backscattering contributions from grain boundaries.
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-51548-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Confinement of Skyrmions in Nanoscale FeGe Device-like Structures.

    Twitchett-Harrison, Alison C / Loudon, James C / Pepper, Ryan A / Birch, Max T / Fangohr, Hans / Midgley, Paul A / Balakrishnan, Geetha / Hatton, Peter D

    ACS applied electronic materials

    2022  Volume 4, Issue 9, Page(s) 4427–4437

    Abstract: Skyrmion-based devices have been proposed as a promising solution for low-energy data storage. These devices include racetrack or logic structures and require skyrmions to be confined in regions with dimensions comparable to the size of a single skyrmion. ...

    Abstract Skyrmion-based devices have been proposed as a promising solution for low-energy data storage. These devices include racetrack or logic structures and require skyrmions to be confined in regions with dimensions comparable to the size of a single skyrmion. Here we examine skyrmions in FeGe device shapes using Lorentz transmission electron microscopy to reveal the consequences of skyrmion confinement in a device-like structure. Dumbbell-shaped elements were created by focused ion beam milling to provide regions where single skyrmions are confined adjacent to areas containing a skyrmion lattice. Simple block shapes of equivalent dimensions were also prepared to allow a direct comparison with skyrmion formation in a less complex, yet still confined, device geometry. The impact of applying a magnetic field and varying the temperature on the formation of skyrmions within the shapes was examined. This revealed that it is not just confinement within a small device structure that controls the position and number of skyrmions but that a complex device geometry changes the skyrmion behavior, including allowing skyrmions to form at lower applied magnetic fields than in simple shapes. The impact of edges in complex shapes is observed to be significant in changing the behavior of the magnetic textures formed. This could allow methods to be developed to control both the position and number of skyrmions within device structures.
    Language English
    Publishing date 2022-09-07
    Publishing country United States
    Document type Journal Article
    ISSN 2637-6113
    ISSN (online) 2637-6113
    DOI 10.1021/acsaelm.2c00692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Multi-dimensional electron microscopy.

    Midgley, Paul A / Thomas, John Meurig

    Angewandte Chemie (International ed. in English)

    2014  Volume 53, Issue 33, Page(s) 8614–8617

    Language English
    Publishing date 2014-08-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.201400625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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