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  1. Article ; Online: Hospitalisation trends from 2019 to 2023 illustrate the persistent resurgence of bronchiolitis in Italy.

    Palmas, Giordano / Resti, Massimo / Indolfi, Giuseppe

    Acta paediatrica (Oslo, Norway : 1992)

    2024  Volume 113, Issue 3, Page(s) 547–549

    MeSH term(s) Humans ; Infant ; Hospitalization ; Bronchiolitis/epidemiology ; Bronchiolitis/therapy ; Italy/epidemiology ; Respiratory Syncytial Virus Infections
    Language English
    Publishing date 2024-01-19
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.17098
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  2. Article ; Online: Severe encephalitis: aetiology, management and outcomes over 10 years in a paediatric intensive care unit.

    Palmas, Giordano / Duke, Trevor

    Archives of disease in childhood

    2023  Volume 108, Issue 11, Page(s) 922–928

    Abstract: Objective: To describe the characteristics, differential diagnoses, management and outcomes of severe encephalitis in children.: Design: A 10-year retrospective cohort study in children admitted to a tertiary paediatric intensive care unit (PICU) ... ...

    Abstract Objective: To describe the characteristics, differential diagnoses, management and outcomes of severe encephalitis in children.
    Design: A 10-year retrospective cohort study in children admitted to a tertiary paediatric intensive care unit (PICU) with suspected encephalitis. One to 6 months' follow-up data were compared between different categories.
    Participants: Patients from 0 to 17 years of age with acute encephalopathy and one or more of fever, seizure, focal neurological findings, cerebrospinal fluid abnormalities, EEG/neuroimaging consistent with encephalitis.
    Main outcome measures: Epidemiology, clinical features, outcomes and risk factor analysis.
    Results: 175 children with encephalitis required intensive care unit (ICU) admission over 10 years. The median age was 4.5 months (IQR 1.6-54.8). The leading cause was enterovirus (n=49, 28%), followed by parechovirus, influenza, herpes simplex virus (HSV), human herpesvirus-6 (HHV-6),
    Conclusions: Encephalitis has a varied aetiology and causes death or severe disability in 1 in every 10 children requiring intensive care.
    MeSH term(s) Child ; Female ; Humans ; Infant ; Child, Preschool ; Influenza, Human/complications ; Retrospective Studies ; Encephalitis/diagnosis ; Encephalitis/epidemiology ; Encephalitis/etiology ; Intensive Care Units, Pediatric ; Enterovirus Infections/complications ; Enterovirus Infections/diagnosis ; Enterovirus Infections/epidemiology ; Enterovirus ; Brain Diseases
    Language English
    Publishing date 2023-07-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2023-325305
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  3. Article ; Online: Disrupted Seasonality of Respiratory Viruses: Retrospective Analysis of Pediatric Hospitalizations in Italy from 2019 to 2023.

    Palmas, Giordano / Trapani, Sandra / Agosti, Massimo / Alberti, Ilaria / Aricò, Maurizio / Azzari, Chiara / Bresesti, Ilia / Bressan, Silvia / Caselli, Desiree / Cazzato, Salvatore / Da Dalt, Liviana / Felici, Enrico / Garazzino, Silvia / Giannattasio, Antonietta / Iudica, Giovanna / Lanari, Marcello / Marchisio, Paola / Martelli, Gaia / Milani, Gregorio Paolo /
    Soro, Federica / Piccotti, Emanuela / Tirelli, Francesca / Resti, Massimo / Indolfi, Giuseppe

    The Journal of pediatrics

    2024  Volume 268, Page(s) 113932

    Abstract: This multicenter study in Italian hospitals highlights the epidemiologic disruptions in the circulation of the 5 main respiratory viruses from 2019 to 2023. Our data reveal a resurgence of respiratory syncytial virus and influenza during the 2022-2023 ... ...

    Abstract This multicenter study in Italian hospitals highlights the epidemiologic disruptions in the circulation of the 5 main respiratory viruses from 2019 to 2023. Our data reveal a resurgence of respiratory syncytial virus and influenza during the 2022-2023 winter season, with an earlier peak in cases for both viruses, emphasizing the importance of timely monitoring.
    MeSH term(s) Humans ; Italy/epidemiology ; Seasons ; Retrospective Studies ; Hospitalization/statistics & numerical data ; Infant ; Child, Preschool ; Child ; Respiratory Tract Infections/epidemiology ; Respiratory Tract Infections/virology ; Respiratory Syncytial Virus Infections/epidemiology ; Influenza, Human/epidemiology ; Male ; Female ; Adolescent ; Infant, Newborn
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2024.113932
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  4. Article ; Online: Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection.

    Venturini, Elisabetta / Palmas, Giordano / Montagnani, Carlotta / Chiappini, Elena / Citera, Francesco / Astorino, Valeria / Trapani, Sandra / Galli, Luisa

    The Journal of pediatrics

    2020  Volume 222, Page(s) 259–261

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Female ; Humans ; Infant ; Infant, Newborn ; Neutropenia/diagnosis ; Neutropenia/therapy ; Neutropenia/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Severity of Illness Index
    Keywords covid19
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2020.04.051
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  5. Article ; Online: Adherence to guideline recommendations in the management of pediatric cardiac arrest: a multicentre observational simulation-based study.

    Corazza, Francesco / Stritoni, Valentina / Martinolli, Francesco / Daverio, Marco / Binotti, Marco / Genoni, Giulia / Ingrassia, Pier Luigi / De Luca, Marco / Palmas, Giordano / Maccora, Ilaria / Frigo, Anna Chiara / Da Dalt, Liviana / Bressan, Silvia

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2022  Volume 29, Issue 4, Page(s) 271–278

    Abstract: Background and importance: Pediatric cardiac arrest is a rare emergency with associated high mortality. Its management is challenging and deviations from guidelines can affect clinical outcomes.: Objectives: To evaluate the adherence to guideline ... ...

    Abstract Background and importance: Pediatric cardiac arrest is a rare emergency with associated high mortality. Its management is challenging and deviations from guidelines can affect clinical outcomes.
    Objectives: To evaluate the adherence to guideline recommendations in the management of a pediatric cardiac arrest scenario by teams of pediatric residents. Secondarily, the association between the use of the Pediatric Advanced Life Support-2015 (PALS-2015) pocket card, and the teams' adherence to international guidelines, were explored.
    Design, settings and participants: Multicentre observational simulation-based study at three Italian University Hospitals in 2018, including PALS-2015 certified pediatric residents in their 3rd-5th year of residency program, divided in teams of three.
    Intervention or exposure: Each team conducted a standard nonshockable pediatric cardiac arrest scenario and independently decided whether to use the PALS-2015 pocket card.
    Outcome measure and analysis: The primary outcome was the overall number and frequency of individual deviations from the PALS-2015 guidelines, measured by the novel c-DEV15plus score (range 0-15). Secondarily, the performance on the validated Clinical Performance Tool for asystole scenarios, the time to perform resuscitation tasks and cardiopulmonary resuscitation (CPR) quality metrics were compared between the teams that used and did not use the PALS-2015 pocket card.
    Main results: Twenty-seven teams (81 residents) were included. Overall, the median number of deviations per scenario was 7 out of 15 [interquartile range (IQR), 6-8]. The most frequent deviations were delays in positioning of a CPR board (92.6%), calling for adrenaline (92.6%), calling for help (88.9%) and incorrect/delayed administration of adrenaline (88.9%). The median Clinical Performance Tool score was 9 out of 13 (IQR, 7-10). The comparison between teams that used ( n  = 13) and did not use ( n  = 14) the PALS-2015 pocket card showed only significantly higher Clinical Performance Tool scores in the former group [9 (IQR 9-10) vs. 7 (IQR 6-8); P  = 0.002].
    Conclusions: Deviations from guidelines, although measured by means of a nonvalidated tool, were frequent in the management of a pediatric cardiac arrest scenario by pediatric residents. The use of the PALS-2015 pocket card was associated with better Clinical Performance Tool scores but was not associated with less deviations or shorter times to resuscitation tasks.
    MeSH term(s) Cardiopulmonary Resuscitation ; Child ; Epinephrine ; Guideline Adherence ; Heart Arrest/therapy ; Humans ; Prospective Studies
    Chemical Substances Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2022-03-29
    Publishing country England
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000000923
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  6. Article: Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection

    Venturini, Elisabetta / Palmas, Giordano / Montagnani, Carlotta / Chiappini, Elena / Citera, Francesco / Astorino, Valeria / Trapani, Sandra / Galli, Luisa

    J Pediatr

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #305926
    Database COVID19

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  7. Article ; Online: Nasal Swab as Preferred Clinical Specimen for COVID-19 Testing in Children.

    Palmas, Giordano / Moriondo, Maria / Trapani, Sandra / Ricci, Silvia / Calistri, Elisa / Pisano, Laura / Perferi, Giancarlo / Galli, Luisa / Venturini, Elisabetta / Indolfi, Giuseppe / Azzari, Chiara

    The Pediatric infectious disease journal

    2020  Volume 39, Issue 9, Page(s) e267–e270

    Abstract: The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal swab testing in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K 0.43, confidence interval 95%, 0.014-0.855). ... ...

    Abstract The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal swab testing in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K 0.43, confidence interval 95%, 0.014-0.855). Benefits might include lower collection-related hazard for healthcare workers. We recommend it as preferred choice for swab-based SARS-CoV-2 testing in children.
    MeSH term(s) Adolescent ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Child ; Child, Preschool ; Clinical Laboratory Techniques/instrumentation ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/virology ; Health Personnel ; Humans ; Infant ; Infant, Newborn ; Nasal Cavity/virology ; Oropharynx/virology ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/virology ; Prospective Studies ; RNA, Viral/isolation & purification ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2 ; Specimen Handling
    Chemical Substances RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-07-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002812
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  8. Article ; Online: NASAL SWAB AS PREFERRED CLINICAL SPECIMEN FOR COVID-19 TESTING IN CHILDREN

    Palmas, Giordano / Moriondo, Maria / Trapani, Sandra / Ricci, Silvia / Calistri, Elisa / Pisano, Laura / Perferi, Giancarlo / Galli, Luisa / Venturini, Elisabetta / Indolfi, Giuseppe / Azzari, Chiara

    Pediatric Infectious Disease Journal

    2020  Volume Publish Ahead of Print

    Keywords Pediatrics, Perinatology, and Child Health ; Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/inf.0000000000002812
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  9. Article: Abstracts of the 78th Annual Scientific Meeting of the American Psychosomatic Society (scheduled for March 2020;cancelled due to the COVID-19 pandemic) NASAL SWAB AS PREFERRED CLINICAL SPECIMEN FOR COVID-19 TESTING IN CHILDREN

    Palmas, Giordano / Moriondo, Maria / Trapani, Sandra / Ricci, Silvia / Calistri, Elisa / Pisano, Laura / Perferi, Giancarlo / Galli, Luisa / Venturini, Elisabetta / Indolfi, Giuseppe / Azzari, Chiara

    Psychosomatic Medicine

    Abstract: ... for correspondence: Giordano Palmas, MD, Department of Health Sciences, University of Florence, viale Pieraccini 24 ... 50137 Florence, Italy E-mail: giordano palmas@unifi it This is an open-access article distributed under ...

    Abstract The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal swab testing in detecting SARS-CoV-2 (Fisher exact test 0 046, Cohen K 0 43, confidence interval 95%, 0 014–0 855) Benefits might include lower collection-related hazard for healthcare workers We recommend it as preferred choice for swab-based SARS-CoV-2 testing in children Accepted for publication June 5, 2020 The authors have no funding or conflicts of interest to disclose Address for correspondence: Giordano Palmas, MD, Department of Health Sciences, University of Florence, viale Pieraccini 24, 50137 Florence, Italy E-mail: giordano palmas@unifi it This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4 0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited The work cannot be changed in any way or used commercially without permission from the journal Copyright © 2020 Wolters Kluwer Health, Inc All rights reserved
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #683141
    Database COVID19

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  10. Article: Nasal Swab as Preferred Clinical Specimen for COVID-19 Testing in Children

    Palmas, Giordano / Moriondo, Maria / Trapani, Sandra / Ricci, Silvia / Calistri, Elisa / Pisano, Laura / Perferi, Giancarlo / Galli, Luisa / Venturini, Elisabetta / Indolfi, Giuseppe / Azzari, Chiara

    Pediatr Infect Dis J

    Abstract: The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal swab testing in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K 0.43, confidence interval 95%, 0.014-0.855). ... ...

    Abstract The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal swab testing in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K 0.43, confidence interval 95%, 0.014-0.855). Benefits might include lower collection-related hazard for healthcare workers. We recommend it as preferred choice for swab-based SARS-CoV-2 testing in children.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #631380
    Database COVID19

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