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  1. Book ; Online: S' attaquer au gaspillage et à l' inefficacité dans le secteur sanitaire / David Parker & William Newbrander

    Parker, David / Newbrander, William

    1994  

    Abstract: Discussion: p. 117- ... ...

    Abstract Discussion: p. 117-136
    Keywords Health resources ; Financial management ; Health care costs ; Costs and cost analysis ; Health Management and Planning
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: How Fragile Are the Results of Randomized Controlled Trials: Is It Time to Rethink How We Analyze Data?: Commentary on an article by Jeffrey L. Shi, BS, et al.: "The Reverse Fragility Index: Interpreting the Current Literature on Long-Term Survivorship of Computer-Navigated Versus Conventional TKA. A Systematic Review and Cross-Sectional Study of Randomized Controlled Trials".

    Parker, David A

    The Journal of bone and joint surgery. American volume

    2023  Volume 105, Issue 2, Page(s) e8

    MeSH term(s) Humans ; Arthroplasty, Replacement, Knee/methods ; Cross-Sectional Studies ; Survivorship ; Randomized Controlled Trials as Topic ; Computers ; Surgery, Computer-Assisted/methods
    Language English
    Publishing date 2023-01-18
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Comment
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.22.01118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Data sharing: putting Nature's policy to the test.

    Chen, Xiwei / Dickinson, Stephanie L / Macagno, Anna L M / Parker, Chelsie M / Allison, David B

    Nature

    2023  Volume 619, Issue 7971, Page(s) 698

    MeSH term(s) Information Dissemination ; Publishing ; Periodicals as Topic ; Reproducibility of Results ; Research Report/standards
    Language English
    Publishing date 2023-07-24
    Publishing country England
    Document type Letter
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-023-02250-z
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
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    Zs.MO 244: Show issues

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  4. Book: Child labour

    Fassa, Anaclaudia G. / Parker, David L. / Scanlon, Thomas J.

    a public health perspective

    2010  

    Author's details ed. by Anaclaudia G. Fassa ; David L. Parker ; Thomas J. Scanlon
    Keywords Child Welfare ; Employment / ethics ; Child Health Services / organization & administration ; Occupational Health Services / organization & administration ; Human Rights Abuses / prevention & control ; Child ; Adolescent
    Language English
    Size XII, 270 S. : Ill., graph. Darst., Kt.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT016442983
    ISBN 978-0-19-955858-2 ; 0-19-955858-2
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2010 A 3659 order for loan Magazin

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  5. Article ; Online: Differences in career paths of alumni of the Cornell Leadership Program from North American universities compared with those alumni from universities in other countries.

    Fraser, David R / Parker, John S L / McGregor, Douglas D

    Journal of the American Veterinary Medical Association

    2023  Volume 261, Issue 5, Page(s) 718–722

    Abstract: Objective: To characterize and compare the careers of alumni of the Cornell Leadership Program for Veterinary Students according to the countries where they studied and obtained their veterinary qualification. The Cornell Leadership Program is a 10-week ...

    Abstract Objective: To characterize and compare the careers of alumni of the Cornell Leadership Program for Veterinary Students according to the countries where they studied and obtained their veterinary qualification. The Cornell Leadership Program is a 10-week residential research experience program for veterinary students from around the world who have ambitions for research-related careers.
    Sample: Data on the career development of all 672 alumni were collected each year over the period of 1990 to 2019.
    Procedures: The annual career profile of each alumnus was recorded and coded in 1 of 28 different categories. The careers and postveterinary qualifications of alumni from universities in the US and Canada (referred to as North American universities) were compared with those alumni who graduated from universities in other countries.
    Results: Analysis of this 30-year database revealed that a considerable proportion (45.7% [307/672]) of the total 672 alumni are following the traditional career path of veterinary clinical practice rather than the research-related careers they aspired to as students during the Leadership Program. Furthermore, a higher proportion of the 325 North American alumni (56% [182/325]) were in clinical practice compared with 33.6% (112/333) of the 333 alumni from other countries.
    Clinical relevance: Many veterinary schools now provide research experience programs to encourage highly talented students who have ambitions for careers in which they can advance knowledge about animal disease and contribute to solving the health problems of animals through hypothesis-based research. Comparison of the careers of the Leadership Program alumni indicates that research experience alone is not sufficient to maintain the career goals of alumni. Follow-up mentoring of alumni of such programs is recommended while they complete their veterinary studies to reinforce their career aspirations and provide advice on how to achieve research-related careers.
    MeSH term(s) Animals ; Humans ; Leadership ; Universities ; Students ; Canada ; Schools, Veterinary ; Career Choice
    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.22.10.0461
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    Zs.A 423: Show issues Location:
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  6. Article ; Online: Deep Learning-based Fibrosis Extent on Computed Tomography Predicts Outcome of Fibrosing Interstitial Lung Disease Independent of Visually Assessed Computed Tomography Pattern.

    Oh, Andrea S / Lynch, David A / Swigris, Jeffrey J / Baraghoshi, David / Dyer, Debra S / Hale, Valerie A / Koelsch, Tilman L / Marrocchio, Cristina / Parker, Katherine N / Teague, Shawn D / Flaherty, Kevin R / Humphries, Stephen M

    Annals of the American Thoracic Society

    2024  Volume 21, Issue 2, Page(s) 218–227

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Humans ; Retrospective Studies ; Deep Learning ; Lung Diseases, Interstitial ; Lung/diagnostic imaging ; Idiopathic Pulmonary Fibrosis ; Prognosis ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202301-084OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Article ; Online: Gambling Habits and Probability Judgements in a Bayesian Task Environment

    Dickinson, David L. / Reid, Parker

    2023  

    Abstract: Little is known about how gamblers estimate probabilities from multiple information sources. This paper reports on a preregistered study that administered an incentivized Bayesian choice task to n=465 participants (self-reported gamblers and non-gamblers) ...

    Abstract Little is known about how gamblers estimate probabilities from multiple information sources. This paper reports on a preregistered study that administered an incentivized Bayesian choice task to n=465 participants (self-reported gamblers and non-gamblers). Our data failed to support our main hypotheses that experienced online gamblers would be more accurate Bayesian decision-makers compared to non-gamblers, that gamblers experienced in games of skill (e.g., poker) would be more accurate than gamblers experienced only in non-skill games (e.g., slots), or that accuracy would differ in females compared to males. Pairwise comparisons between these types of participants also failed to show any difference in decision weights placed on the two information sources. Exploratory analysis, however, revealed interesting effects related to self-reported gambling frequency. Specifically, more frequent online gamblers had lower Bayesian accuracy than infrequent gamblers. Also, those scoring higher in a cognitive reflection task were more Bayesian in weighting information sources when making belief assessments. While we report no main effect of sex on Bayesian accuracy, exploratory analysis found that the decline in accuracy linked to self-reported gambling frequency was stronger for females. Decision modeling found a decreased weight placed on new evidence (over base rate odds) in those who showed decreased accuracy, which suggests a proper incorporation of new information into one's probability assessments is important for more accurate assessment of probabilities in uncertain environments. Our results link frequency of gambling to worse performance in the critical probability assessment skills that should benefit gambling success (i.e., in skill-based games).
    Keywords ddc:330 ; C91 ; D91 ; D83 ; gambling ; Bayes rule ; probability judgements ; cognitive reflection
    Subject code 150
    Language English
    Publisher Bonn: Institute of Labor Economics (IZA)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Affinity Purification-Mass Spectrometry and Single Fiber Physiology/Proteomics Reveals Mechanistic Insights of C18ORF25.

    Ng, Yaan-Kit / Blazev, Ronnie / McNamara, James W / Dutt, Mriga / Molendijk, Jeffrey / Porrello, Enzo R / Elliott, David A / Parker, Benjamin L

    Journal of proteome research

    2024  Volume 23, Issue 4, Page(s) 1285–1297

    Abstract: C18ORF25 was recently shown to be phosphorylated at S67 by AMP-activated protein kinase (AMPK) in the skeletal muscle, following acute exercise in humans. Phosphorylation was shown to improve the ex vivo skeletal muscle contractile function in mice, but ... ...

    Abstract C18ORF25 was recently shown to be phosphorylated at S67 by AMP-activated protein kinase (AMPK) in the skeletal muscle, following acute exercise in humans. Phosphorylation was shown to improve the ex vivo skeletal muscle contractile function in mice, but our understanding of the molecular mechanisms is incomplete. Here, we profiled the interactome of C18ORF25 in mouse myotubes using affinity purification coupled to mass spectrometry. This analysis included an investigation of AMPK-dependent and S67-dependent protein/protein interactions. Several nucleocytoplasmic and contractile-associated proteins were identified, which revealed a subset of GTPases that associate with C18ORF25 in an AMPK- and S67 phosphorylation-dependent manner. We confirmed that C18ORF25 is localized to the nucleus and the contractile apparatus in the skeletal muscle. Mice lacking
    MeSH term(s) Mice ; Humans ; Animals ; Muscle Fibers, Slow-Twitch/metabolism ; AMP-Activated Protein Kinases/metabolism ; Proteomics/methods ; Calcium/metabolism ; Muscle Fibers, Skeletal/metabolism ; Muscle Fibers, Fast-Twitch/metabolism ; Muscle, Skeletal/metabolism ; Muscle Contraction ; Mass Spectrometry
    Chemical Substances AMP-Activated Protein Kinases (EC 2.7.11.31) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2078618-9
    ISSN 1535-3907 ; 1535-3893
    ISSN (online) 1535-3907
    ISSN 1535-3893
    DOI 10.1021/acs.jproteome.3c00716
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  9. Article ; Online: Impact of sustained calorie restriction and weight cycling on body composition in high-fat diet-fed male and female C57BL/6J mice.

    Smith, Daniel L / Yang, Yongbin / Mestre, Luis M / Henschel, Beate / Parker, Erik / Dickinson, Stephanie / Patki, Amit / Allison, David B / Nagy, Tim R

    Obesity (Silver Spring, Md.)

    2024  Volume 32, Issue 5, Page(s) 959–968

    Abstract: Objective: The objective of this study was to investigate body composition changes with weight cycling (WC) among adult C57BL/6J mice with diet-induced obesity.: Methods: A total of 555 single-housed mice were fed a high-fat diet ad libitum (AL) from ...

    Abstract Objective: The objective of this study was to investigate body composition changes with weight cycling (WC) among adult C57BL/6J mice with diet-induced obesity.
    Methods: A total of 555 single-housed mice were fed a high-fat diet ad libitum (AL) from 8 to 43 weeks of age. The 200 heaviest mice of each sex were randomized to the following four groups: ever obese (EO, continued AL feeding); obese weight loser (OWL, calorie-restricted); obese weight loser moderate (OWLM, body weight halfway between EO and OWL); and WC (diet restricted to OWL followed by AL refeeding cycles). Body weight and composition data were collected. Linear regression was used to calculate residuals between predicted and observed fat mass. Linear mixed models were used to compare diet groups.
    Results: Although weight loss and regain resulted in changes in body weight and composition, fat mass, body weight, and relative body fat were not significantly greater for the WC group compared with the EO group. During long-term calorie restriction, males (but not females) in the OWLM group remained relatively fatter than the EO group.
    Conclusions: WC did not increase body weight or relative fat mass for middle-aged, high-fat diet-fed adult mice. However, long-term moderate calorie restriction resulted in lower body weight but greater "relative" fat in male mice.
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2230457-5
    ISSN 1930-739X ; 1071-7323 ; 1930-7381
    ISSN (online) 1930-739X
    ISSN 1071-7323 ; 1930-7381
    DOI 10.1002/oby.24015
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  10. Article ; Online: Determination of molecular hydration in solution

    Giansiracusa, Marcus J / Vonci, Michele / Whyatt, Yasmin L / Williams, Carys / Mason, Kevin / Parker, David / McInnes, Eric J L / Chilton, Nicholas F

    Chemical communications (Cambridge, England)

    2023  Volume 59, Issue 30, Page(s) 4531–4534

    Abstract: The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to ... ...

    Abstract The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a
    Language English
    Publishing date 2023-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc00601h
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