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  1. Article: Pharmacological Advances for Treatment in Hypertension.

    Gasparotto Junior, Arquimedes

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 17, Issue 1

    Abstract: Hypertension plays a significant role in the development of cardiovascular disease and renal diseases, which can heighten the likelihood of experiencing related conditions like myocardial infarction, stroke, and heart failure [ ... ]. ...

    Abstract Hypertension plays a significant role in the development of cardiovascular disease and renal diseases, which can heighten the likelihood of experiencing related conditions like myocardial infarction, stroke, and heart failure [...].
    Language English
    Publishing date 2023-12-27
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17010039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Biologically active products as therapeutic options for the treatment of cardiovascular diseases related to liver injury.

    Gasparotto Junior, Arquimedes / Lívero, Francislaine Aparecida Dos Reis / Acco, Alexandra

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 1041020

    Language English
    Publishing date 2022-10-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.1041020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Ateroprotective effects of

    Cestari, Ana Paula / Gasparotto, Francielly Mourão / Kassuya, Cândida Aparecida Leite / Lacerda, Tauany Milan Ribeiro / Donadel, Guilherme / Moura, Catia Sari / Ceranto, Daniela Boleta / Jacomassi, Ezilda / Alberton, Odair / Tramontini, Salviano Belletini / Bertoncello, Luana Ale / Gasparotto Junior, Arquimedes / Lourenço, Emerson Luiz Botelho

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1244632

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1244632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Phytochemistry and Pharmacology of the Genus

    Boeing, Thaise / Tafarelo Moreno, Karyne Garcia / Gasparotto Junior, Arquimedes / Mota da Silva, Luisa / de Souza, Priscila

    Evidence-based complementary and alternative medicine : eCAM

    2021  Volume 2021, Page(s) 6658434

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2021-03-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2021/6658434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
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  5. Article: Extraction Methods, Chemical Characterization, and In Vitro Biological Activities of

    Pinc, Mariana Moraes / Dalmagro, Mariana / da Cruz Alves Pereira, Elton / Donadel, Guilherme / Thomaz, Renan Tedeski / da Silva, Camila / Macruz, Paula Derksen / Jacomassi, Ezilda / Gasparotto Junior, Arquimedes / Hoscheid, Jaqueline / Lourenço, Emerson Luiz Botelho / Alberton, Odair

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 16, Issue 8

    Abstract: ... Plinia ... ...

    Abstract Plinia cauliflora
    Language English
    Publishing date 2023-08-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph16081173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Role of K

    Moser, Jeniffer Cristóvão / da Silva, Rita de Cássia Vilhena / Costa, Philipe / da Silva, Luisa Mota / Cassemiro, Nadla Soares / Gasparotto Junior, Arquimedes / Silva, Denise Brentan / de Souza, Priscila

    Cardiovascular therapeutics

    2023  Volume 2023, Page(s) 9948707

    Abstract: Plectranthus ... ...

    Abstract Plectranthus barbatus
    MeSH term(s) Rats ; Animals ; Vasodilator Agents/pharmacology ; Plectranthus ; Peumus ; Vasodilation ; Brazil ; Hypertension ; Rats, Inbred SHR ; Enzyme Inhibitors/pharmacology ; Endothelium, Vascular
    Chemical Substances Vasodilator Agents ; gamma-hydroxy-gamma-ethyl-gamma-phenylbutyramide (67880-30-2) ; Enzyme Inhibitors
    Language English
    Publishing date 2023-11-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2428378-2
    ISSN 1755-5922 ; 1755-5914
    ISSN (online) 1755-5922
    ISSN 1755-5914
    DOI 10.1155/2023/9948707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2474: Show issues Location:
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  7. Article ; Online: Bacopa monnieri

    Santos, Andreia Fuentes Dos / Souza, Marília Moraes Queiroz / Amaral, Eduarda Carolina / Albuquerque, Edilson Rodrigues / Bortoloti, Durcelina Schiavoni / Gasparotto Junior, Arquimedes / Lourenço, Emerson Luiz Botelho / Lovato, Evellyn Claudia Wietzikoski / Lívero, Francislaine Aparecida Dos Reis

    Journal of medicinal food

    2023  Volume 26, Issue 2, Page(s) 114–119

    Abstract: ... Bacopa ... ...

    Abstract Bacopa monnieri
    MeSH term(s) Humans ; Parkinson Disease/drug therapy ; Plant Extracts/pharmacology ; Bacopa ; Pilot Projects ; Quality of Life
    Chemical Substances Plant Extracts
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1427365-2
    ISSN 1557-7600 ; 1096-620X
    ISSN (online) 1557-7600
    ISSN 1096-620X
    DOI 10.1089/jmf.2022.0106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5916: Show issues Location:
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  8. Article: Cardioprotective Effects of

    Lopes, Katiana Simões / Marques, Aline Aparecida Macedo / Moreno, Karyne Garcia Tafarelo / Dos Santos, Ariany Carvalho / Souza, Roosevelt Isaías Carvalho / Lourenço, Emerson Luiz Botelho / Oliveira, Rodrigo Juliano / Gomes, Roberto da Silva / Lívero, Francislaine Aparecida Dos Reis / Gasparotto Junior, Arquimedes

    Evidence-based complementary and alternative medicine : eCAM

    2023  Volume 2023, Page(s) 6611569

    Abstract: ... Solidago ... ...

    Abstract Solidago microglossa
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2023/6611569
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article: Boldine, an Alkaloid from

    de Souza, Priscila / da Silva, Rita de Cássia Vilhena / da Silva, Luisa Mota / Steimbach, Viviane Miranda Bispo / Moreno, Karyne Garcia Tafarelo / Gasparotto Junior, Arquimedes

    Evidence-based complementary and alternative medicine : eCAM

    2022  Volume 2022, Page(s) 4560607

    Abstract: Boldine, 2,9-dihydroxy-1,10-dimethoxyaporphine, is the main alkaloid found in the leaves and bark ... ...

    Abstract Boldine, 2,9-dihydroxy-1,10-dimethoxyaporphine, is the main alkaloid found in the leaves and bark of
    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2022/4560607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
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  10. Article ; Online: Cardioprotective Effects of Aloysia polystachya Essential Oil on a Rat Model with Multiple Cardiovascular Risk Factors.

    Moreno, Karyne Garcia Tafarelo / Marques, Aline Aparecida Macedo / da Silva, Gabriela Pereira / Bertoncelo, Luana Ale / Pessoal, Luciane Barbosa / Gonçalves, Larissa Dantas / Dos Santos, Ariany Carvalho / Souza, Roosevelt Isaías Carvalho / Silva, Denise Brentan / Gasparotto Junior, Arquimedes

    Planta medica

    2024  

    Abstract: Traditional medicine is a frequently utilized method to treat cardiovascular disease and its primary risk factors, including hypertension and dyslipidemia. Aloysia polystachya is a species that is commonly employed to treat various pathological ... ...

    Abstract Traditional medicine is a frequently utilized method to treat cardiovascular disease and its primary risk factors, including hypertension and dyslipidemia. Aloysia polystachya is a species that is commonly employed to treat various pathological conditions, and it has already been identified as having some cardioprotective effects. This study aimed to investigate the protective effects of the essential oil extracted from the leaves of A. polystachya in a rat model that simulates multiple cardiovascular risk factors. We evaluate the acute toxicity, as well as the cardioprotective effects, by giving different doses of A. polystachya essential oil (1.47 mg/kg, 4.40 mg/kg, and 13.20 mg/kg) over a period of 42 days. The control group was treated with rosuvastatin (5 mg/kg). At the end of the treatments, the renal function, electrocardiography, blood pressure, vascular reactivity, serum biochemical profile, and organ histopathology were evaluated. The main compounds identified in the essential oil of A. polystachya using gas chromatography coupled with mass spectrometry were beta-myrcene (1.08%), limonene (40.13%), and carvone (56.47%). The essential oil of A. polystachya not only lacks acute toxicity but also mitigates the reduction in the excretion of sodium, chloride, and creatinine in urine. Furthermore, it reduces electrocardiographic abnormalities and decreases blood pressure levels. Moreover, this treatment prevents an elevation in markers of inflammation and oxidative stress in the bloodstream. Our findings indicate significant cardioprotective effects of the essential oil of A. polystachya against multiple risk factors for cardiovascular diseases in hypertensive rats.
    Language English
    Publishing date 2024-04-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 123545-x
    ISSN 1439-0221 ; 0032-0943
    ISSN (online) 1439-0221
    ISSN 0032-0943
    DOI 10.1055/a-2294-6922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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