LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 6992

Search options

  1. Article: [Prof. YUE Mei-zhong, a great master for classical prescriptions].

    Xiong, Xing-Jiang

    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

    2012  Volume 32, Issue 7, Page(s) 877–878

    MeSH term(s) Integrative Medicine
    Language Chinese
    Publishing date 2012-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 1195456-5
    ISSN 1003-5370
    ISSN 1003-5370
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Protective effect of Fufang-Liu-Yue-Qing, a traditional Chinese herbal formula, on CCl4 induced liver fibrosis in rats.

    Lin, Xing / Zhang, Shijun / Huang, Quanfang / Wei, Ling / Zheng, Li / Chen, Zhaoni / Jiao, Yang / Huang, Jianchun / Fu, Shujie / Huang, Renbin

    Journal of ethnopharmacology

    2012  Volume 142, Issue 2, Page(s) 548–556

    Abstract: Ethnopharmacological relevance: Chinese prescription Fufang-Liu-Yue-Qing (FLYQ) has long been ...

    Abstract Ethnopharmacological relevance: Chinese prescription Fufang-Liu-Yue-Qing (FLYQ) has long been employed clinically to treat chronic hepatitis B, and we have reported its beneficial effects on liver fibrosis in vitro. The present study was investigated to verify protective effects of FLYQ on liver fibrosis in a rat model and to investigate the underlying mechanisms which have not been explored yet.
    Materials and methods: Liver fibrosis was established by intragastric administration of 2 ml/kg CCl(4) twice a week for 12 weeks. During the experiment, the model group received CCl(4) only, and the normal control group received an equal volume of saline. Treatment groups received not only CCl(4) for 12 weeks, but also the corresponding drugs, colchicine (1.00 mg/kg/day) or FLYQ (300, 150, 75 mg/kg/day) from 5 to 12 weeks.
    Results: Analysis experiments showed that FLYQ could significantly alleviate liver injury, as indicated by decreasing levels of ALT, AST, ALP, GGT, IL-6 and TNF-α. Moreover, FLYQ could effectively inhibit collagen deposition and reduce the pathological tissue damage. Research on mechanism showed that FLYQ was able to markedly reduce lipid peroxidation, recruit the anti-oxidative defense system, promote ECM degradation by modulating the levels of TIMP-1 and MMP-2, and induce HSC apoptosis by down-regulating bcl-2 mRNA, as well as inhibit the expressions of α-SMA and TGF-β(1) proteins.
    Conclusions: Our results show that FLYQ is effective in attenuating hepatic injury and fibrosis in the CCl(4)-induced rat model, which should be developed as a new drug for treatment of liver fibrosis and even cirrhosis.
    MeSH term(s) Actins/metabolism ; Animals ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Apoptosis/drug effects ; Carbon Tetrachloride ; Chemical and Drug Induced Liver Injury/drug therapy ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/pathology ; Colchicine ; Collagen/metabolism ; Down-Regulation ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Interleukin-6/metabolism ; Lipid Peroxidation/drug effects ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis, Experimental/drug therapy ; Liver Cirrhosis, Experimental/metabolism ; Liver Cirrhosis, Experimental/pathology ; Magnoliopsida ; Male ; Matrix Metalloproteinase 2/metabolism ; Phytotherapy ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar ; Tissue Inhibitor of Metalloproteinase-1/metabolism ; Transaminases/metabolism ; Transforming Growth Factor beta/metabolism ; Tumor Necrosis Factor-alpha/metabolism
    Chemical Substances Actins ; Antioxidants ; Drugs, Chinese Herbal ; Interleukin-6 ; Proto-Oncogene Proteins c-bcl-2 ; RNA, Messenger ; Tissue Inhibitor of Metalloproteinase-1 ; Transforming Growth Factor beta ; Tumor Necrosis Factor-alpha ; smooth muscle actin, rat ; Collagen (9007-34-5) ; Carbon Tetrachloride (CL2T97X0V0) ; Transaminases (EC 2.6.1.-) ; Matrix Metalloproteinase 2 (EC 3.4.24.24) ; Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2012-07-13
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2012.05.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Book: Yue yaér

    Huo, Zhuang / Xing, Dan / Xu, Xiaoxing

    1995  

    Author's details [Regie: Huo Zhuang, Xu Xiaoxing, Xing Dan]
    Language Chinese
    Size 2 VCDs, 88 Min
    Publishing place China
    Document type Book
    Note Audiosprache: Chinesisch
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  4. Book: Yue ya er

    Huo, Zhuang / Xing, Dan / Xu, Xiaoxing

    Crescent moon

    1995  

    Author's details [Regie: Huo Zhuang, Xu Xiaoxing, Xing Dan]
    Language Chinese
    Size 2 VCDs, 88 Min
    Publishing place China
    Document type Book
    Note Audiosprache: Chinesisch
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  5. Article: Protective effect of Fufang-Liu-Yue-Qing, a traditional Chinese herbal formula, on CCl₄ induced liver fibrosis in rats

    Lin, Xing / Zhang, Shijun / Huang, Quanfang / Wei, Ling / Zheng, Li / Chen, Zhaoni / Jiao, Yang / Huang, Jianchun / Fu, Shujie / Huang, Renbin

    Journal of ethnopharmacology. 2012 July 13, v. 142, no. 2

    2012  

    Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Chinese prescription Fufang-Liu-Yue-Qing (FLYQ) has long been ...

    Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Chinese prescription Fufang-Liu-Yue-Qing (FLYQ) has long been employed clinically to treat chronic hepatitis B, and we have reported its beneficial effects on liver fibrosis in vitro. The present study was investigated to verify protective effects of FLYQ on liver fibrosis in a rat model and to investigate the underlying mechanisms which have not been explored yet. MATERIALS AND METHODS: Liver fibrosis was established by intragastric administration of 2ml/kg CCl₄ twice a week for 12 weeks. During the experiment, the model group received CCl₄ only, and the normal control group received an equal volume of saline. Treatment groups received not only CCl₄ for 12 weeks, but also the corresponding drugs, colchicine (1.00mg/kg/day) or FLYQ (300, 150, 75mg/kg/day) from 5 to 12 weeks. RESULTS: Analysis experiments showed that FLYQ could significantly alleviate liver injury, as indicated by decreasing levels of ALT, AST, ALP, GGT, IL-6 and TNF-α. Moreover, FLYQ could effectively inhibit collagen deposition and reduce the pathological tissue damage. Research on mechanism showed that FLYQ was able to markedly reduce lipid peroxidation, recruit the anti-oxidative defense system, promote ECM degradation by modulating the levels of TIMP-1 and MMP-2, and induce HSC apoptosis by down-regulating bcl-2 mRNA, as well as inhibit the expressions of α-SMA and TGF-β₁ proteins. CONCLUSIONS: Our results show that FLYQ is effective in attenuating hepatic injury and fibrosis in the CCl₄-induced rat model, which should be developed as a new drug for treatment of liver fibrosis and even cirrhosis.
    Keywords alanine transaminase ; animal models ; apoptosis ; aspartate transaminase ; carbon tetrachloride ; chronic hepatitis B ; colchicine ; collagen ; drug therapy ; drugs ; fibrosis ; interleukin-6 ; intragastric administration ; lipid peroxidation ; liver ; liver cirrhosis ; messenger RNA ; protective effect ; rats ; tumor necrosis factor-alpha
    Language English
    Dates of publication 2012-0713
    Size p. 548-556.
    Publishing place Elsevier Ireland Ltd
    Document type Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2012.05.040
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  6. Book ; Online: Adversarial Training with Generated Data in High-Dimensional Regression

    Xing, Yue

    An Asymptotic Study

    2023  

    Abstract: In recent years, studies such as \cite{carmon2019unlabeled,gowal2021improving,xing2022artificial} have demonstrated that incorporating additional real or generated data with pseudo-labels can enhance adversarial training through a two-stage training ... ...

    Abstract In recent years, studies such as \cite{carmon2019unlabeled,gowal2021improving,xing2022artificial} have demonstrated that incorporating additional real or generated data with pseudo-labels can enhance adversarial training through a two-stage training approach. In this paper, we perform a theoretical analysis of the asymptotic behavior of this method in high-dimensional linear regression. While a double-descent phenomenon can be observed in ridgeless training, with an appropriate $\mathcal{L}_2$ regularization, the two-stage adversarial training achieves a better performance. Finally, we derive a shortcut cross-validation formula specifically tailored for the two-stage training method.
    Keywords Statistics - Machine Learning ; Computer Science - Machine Learning
    Publishing date 2023-06-21
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  7. Article ; Online: DNA methylation variation and growth in the clonal

    Quan, Jiaxin / Song, Shanshan / Xing, Linya / Liu, Xiao / Yue, Ming

    Epigenetics

    2024  Volume 19, Issue 1, Page(s) 2305078

    Abstract: Studies suggest that clonal plants' ability to select habitats and forage in a heterogeneous environment is influenced by their past environment, with stress legacy potentially playing a crucial role. In this study, we examined parental ramets ... ...

    Abstract Studies suggest that clonal plants' ability to select habitats and forage in a heterogeneous environment is influenced by their past environment, with stress legacy potentially playing a crucial role. In this study, we examined parental ramets of
    MeSH term(s) Humans ; Infant, Newborn ; DNA Methylation ; Lead/toxicity ; Biomass ; Epigenomics ; Phenotype
    Chemical Substances Lead (2P299V784P)
    Language English
    Publishing date 2024-01-21
    Publishing country United States
    Document type Journal Article
    ISSN 1559-2308
    ISSN (online) 1559-2308
    DOI 10.1080/15592294.2024.2305078
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Comparative efficacy of Chinese herbal injections in patients with cardiogenic shock (CS): a systematic review and Bayesian network meta-analysis of randomized controlled trials.

    Yue, Linkai / Xiao, Lu / Zhang, Xuemin / Niu, Liqing / Wen, Yue / Li, Xiaowei / Wang, Ying / Xing, Guanghe / Li, Guiwei

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1348360

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1348360
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Facet-Dependent Interfacial Charge Transfer between T-Phase VS

    Wang, Jingjing / Huang, Chenxi / Xing, Yue / Shao, Xiang

    ACS applied materials & interfaces

    2024  

    Abstract: The hybridizations of two-dimensional (2D) metallic materials with semiconducting transition metal oxides (TMOs) register attractive heterojunctions, which can find various applications in photostimulated circumstances. In this work, we developed an ... ...

    Abstract The hybridizations of two-dimensional (2D) metallic materials with semiconducting transition metal oxides (TMOs) register attractive heterojunctions, which can find various applications in photostimulated circumstances. In this work, we developed an ambient-pressure chemical vapor deposition method to directly grow T-VS
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.4c01437
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Characterisation of an IncX4 plasmid harbouring mcr-1 from Escherichia fergusonii from chicken meat in China.

    Mei, Cai-Yue / Zhang, Xing-Xing / Jiang, Yue / Ma, Qin-Chun / Wang, Zhen-Yu / Jiao, Xinan / Zhong, Fa-Gang / Wang, Jing

    Journal of global antimicrobial resistance

    2024  Volume 37, Page(s) 8–10

    Language English
    Publishing date 2024-02-25
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7173
    ISSN (online) 2213-7173
    ISSN 2213-7173
    DOI 10.1016/j.jgar.2024.02.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top