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  1. Book: IgE antibodies: Generation and function

    Lafaille, Juan J. / Curotto de Lafaille, Maria A.

    (Current topics in microbiology and immunology ; 388)

    2015  

    Author's details Juan J. Lafaille ; Maria A. Curotto de Lafaille eds
    Series title Current topics in microbiology and immunology ; 388
    Collection
    Language English
    Size IX, 152 S. : graph. Darst.
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018546137
    ISBN 978-3-319-13724-7 ; 3-319-13724-7 ; 9783319137254 ; 3319137255
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Making good of a tricky start: How IgE and mast cells manage a protective sway in food allergy.

    Miranda-Waldetario, Mariana C G / Curotto de Lafaille, Maria A

    Immunity

    2023  Volume 56, Issue 9, Page(s) 1988–1990

    Abstract: The immune and nervous systems respond to dangerous stimuli to maintain homeostasis. In a recent issue of Nature, Florsheim et al. and Plum et al. uncover the crosstalk between immunoglobulin E (IgE)-mast-cell-mediated immune activation and neural ... ...

    Abstract The immune and nervous systems respond to dangerous stimuli to maintain homeostasis. In a recent issue of Nature, Florsheim et al. and Plum et al. uncover the crosstalk between immunoglobulin E (IgE)-mast-cell-mediated immune activation and neural responses driving behavioral avoidance of allergenic food.
    MeSH term(s) Humans ; Mast Cells ; Food Hypersensitivity ; Antigen Presentation ; Cross Reactions ; Immunoglobulin E
    Chemical Substances Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1217235-2
    ISSN 1097-4180 ; 1074-7613
    ISSN (online) 1097-4180
    ISSN 1074-7613
    DOI 10.1016/j.immuni.2023.08.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: CD23

    Ota, Miyo / Hoehn, Kenneth B / Fernandes-Braga, Weslley / Ota, Takayuki / Aranda, Carlos J / Friedman, Sara / Miranda-Waldetario, Mariana G C / Redes, Jamie / Suprun, Maria / Grishina, Galina / Sampson, Hugh A / Malbari, Alefiyah / Kleinstein, Steven H / Sicherer, Scott H / Curotto de Lafaille, Maria A

    Science translational medicine

    2024  Volume 16, Issue 733, Page(s) eadi0673

    Abstract: Food allergy is caused by allergen-specific immunoglobulin E (IgE) antibodies, but little is known about the B cell memory of persistent IgE responses. Here, we describe, in human pediatric peanut allergy, a population of ... ...

    Abstract Food allergy is caused by allergen-specific immunoglobulin E (IgE) antibodies, but little is known about the B cell memory of persistent IgE responses. Here, we describe, in human pediatric peanut allergy, a population of CD23
    MeSH term(s) Humans ; Child ; Peanut Hypersensitivity ; Memory B Cells ; Immunoglobulin G ; Food Hypersensitivity ; Allergens ; Immunoglobulin E
    Chemical Substances Immunoglobulin G ; Allergens ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2518854-9
    ISSN 1946-6242 ; 1946-6234
    ISSN (online) 1946-6242
    ISSN 1946-6234
    DOI 10.1126/scitranslmed.adi0673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Secret Life of IgE-Producing Cells.

    Aranda, Carlos J / Curotto de Lafaille, Maria A

    Immunity

    2019  Volume 50, Issue 2, Page(s) 285–287

    Abstract: IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Their findings provide insight into the differentiation of IgE cells in humans ... ...

    Abstract IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Their findings provide insight into the differentiation of IgE cells in humans and have implications for our understanding of allergic disease.
    MeSH term(s) Allergens ; B-Lymphocytes ; Humans ; Hypersensitivity ; Immunoglobulin E ; Transcriptome
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2019-03-26
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1217235-2
    ISSN 1097-4180 ; 1074-7613
    ISSN (online) 1097-4180
    ISSN 1074-7613
    DOI 10.1016/j.immuni.2019.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Reaginic antibodies.

    Lafaille, Juan J / Curotto de Lafaille, Maria A

    Current topics in microbiology and immunology

    2015  Volume 388, Page(s) v–vii

    MeSH term(s) Animals ; Humans ; Immunoglobulin E/physiology
    Chemical Substances Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2015
    Publishing country Germany
    Document type Introductory Journal Article
    ISSN 0070-217X
    ISSN 0070-217X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The memory of pathogenic IgE is contained within CD23

    Ota, Miyo / Hoehn, Kenneth B / Ota, Takayuki / Aranda, Carlos J / Friedman, Sara / Braga, Weslley F / Malbari, Alefiyah / Kleinstein, Steven H / Sicherer, Scott H / Curotto de Lafaille, Maria A

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Food allergy is caused by allergen-specific IgE antibodies but little is known about the B cell memory of persistent IgE responses. Here we describe in human pediatric peanut allergy CD23 : One-sentence summary: We describe a unique population of ... ...

    Abstract Food allergy is caused by allergen-specific IgE antibodies but little is known about the B cell memory of persistent IgE responses. Here we describe in human pediatric peanut allergy CD23
    One-sentence summary: We describe a unique population of IgG
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.01.25.525506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pre-existing antibody allows for maturation of new B cells in 'recall' germinal centres.

    Herb, Jake / Curotto de Lafaille, Maria

    Nature reviews. Immunology

    2024  

    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-024-01012-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Non-classical B Cell Memory of Allergic IgE Responses.

    Saunders, Sean P / Ma, Erica G M / Aranda, Carlos J / Curotto de Lafaille, Maria A

    Frontiers in immunology

    2019  Volume 10, Page(s) 715

    Abstract: The long-term effectiveness of antibody responses relies on the development of humoral immune memory. Humoral immunity is maintained by long-lived plasma cells that secrete antigen-specific antibodies, and memory B cells that rapidly respond to antigen ... ...

    Abstract The long-term effectiveness of antibody responses relies on the development of humoral immune memory. Humoral immunity is maintained by long-lived plasma cells that secrete antigen-specific antibodies, and memory B cells that rapidly respond to antigen re-exposure by generating new plasma cells and memory B cells. Developing effective immunological memory is essential for protection against pathogens, and is the basis of successful vaccinations. IgE responses have evolved for protection against helminth parasites infections and against toxins, but IgE is also a potent mediator of allergic diseases. There has been a dramatic increase in the incidence of allergic diseases in recent decades and this has provided the impetus to study the nature of IgE antibody responses. As will be discussed in depth in this review, the IgE memory response has unique features that distinguish it from classical B cell memory.
    MeSH term(s) Anaphylaxis/immunology ; Animals ; Germinal Center/immunology ; Humans ; Hypersensitivity/immunology ; Immunity, Humoral/immunology ; Immunoglobulin Class Switching/genetics ; Immunoglobulin Class Switching/immunology ; Immunoglobulin E/immunology ; Immunoglobulin G/immunology ; Immunologic Memory/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Plasma Cells/immunology
    Chemical Substances Immunoglobulin G ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2019-04-26
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2019.00715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: IgE antibodies: generation and function

    Curotto de Lafaille, Maria A / Lafaille, Juan J

    (Current topics in microbiology and immunology ; 388)

    2015  

    Author's details Juan J. Lafaille ; Maria A. Curotto de Lafaille, ed
    Series title Current topics in microbiology and immunology ; 388
    Language English
    Size ix, 152 S, 235 mm x 155 mm
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    ISBN 9783319137247 ; 3319137247
    Database Special collection on veterinary medicine and general parasitology

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  10. Book: IgE antibodies: generation and function

    Curotto de Lafaille, Maria A / Lafaille, Juan J

    (Current topics in microbiology and immunology ; 388)

    2015  

    Author's details Juan J. Lafaille ; Maria A. Curotto de Lafaille, ed
    Series title Current topics in microbiology and immunology ; 388
    Language English
    Size ix, 152 S, 235 mm x 155 mm
    Document type Book
    ISBN 9783319137247 ; 3319137247
    Database Friedrich Loeffler-Institute, Federal Research Institute for Animal Health

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