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  1. Book ; Online ; E-Book: Management of high altitude pathophysiology

    Misra, Kshipra / Sharma, Priyanka / Bhardwaj, Anuja

    2018  

    Author's details edited by Kshipra Misra, Priyanka Sharma, Anuja Bhardwaj
    Keywords Anoxemia ; Altitude, Influence of ; Oxygen in the body
    Subject code 616.2
    Language English
    Size 1 Online-Ressource (xiv, 329 Seiten), Illustrationen
    Publisher Elsevier AP
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019789121
    ISBN 978-0-12-814000-0 ; 9780128139998 ; 0-12-814000-3 ; 0128139994
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Corrigendum to 'Metabolomic insight into the synergistic mechanism of action of a bacterial consortium in plant growth promotion' [J. Biosci. Bioeng. 134 (5) (2022) 399-406].

    Priyanka / Srivastava, Sonal / Sharma, Shilpi

    Journal of bioscience and bioengineering

    2023  Volume 135, Issue 4, Page(s) 348

    Language English
    Publishing date 2023-02-23
    Publishing country Japan
    Document type Published Erratum
    ZDB-ID 1465387-4
    ISSN 1347-4421 ; 1389-1723
    ISSN (online) 1347-4421
    ISSN 1389-1723
    DOI 10.1016/j.jbiosc.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4728: Show issues

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  3. Article ; Online: Time to Optimize Deescalation Strategies in Triple-Negative Breast Cancer?

    Sharma, Priyanka

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2022  Volume 28, Issue 22, Page(s) 4840–4842

    Abstract: Pathologic response serves as a tool to optimize escalation and deescalation of adjuvant treatment. Neoadjuvant carboplatin-taxane combination is a promising chemotherapy deescalation strategy for triple-negative breast cancer. Many key points, such as ... ...

    Abstract Pathologic response serves as a tool to optimize escalation and deescalation of adjuvant treatment. Neoadjuvant carboplatin-taxane combination is a promising chemotherapy deescalation strategy for triple-negative breast cancer. Many key points, such as trial design/patient selection, response biomarkers, role of immunotherapy, and patient advocate input, will have to be carefully considered in order to advance neoadjuvant chemotherapy deescalation investigations. See related article by Gluz et al., p. 4995.
    MeSH term(s) Humans ; Neoadjuvant Therapy ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/genetics ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carboplatin/administration & dosage ; Survival Analysis ; Biomarkers
    Chemical Substances Carboplatin (BG3F62OND5) ; Biomarkers
    Language English
    Publishing date 2022-09-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-22-2140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4223: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: C-terminal region of Rv1039c (PPE15) protein of Mycobacterium tuberculosis targets host mitochondria to induce macrophage apoptosis.

    Priyanka / Sharma, Sadhna / Varma-Basil, Mandira / Sharma, Monika

    Apoptosis : an international journal on programmed cell death

    2024  

    Abstract: Mycobacterium tuberculosis (Mtb) genome possesses a unique family called Proline-Glutamate/Proline-Proline-Glutamate (PE/PPE) gene family, exclusive to pathogenic mycobacterium. Some of these proteins are known to play role in virulence and immune ... ...

    Abstract Mycobacterium tuberculosis (Mtb) genome possesses a unique family called Proline-Glutamate/Proline-Proline-Glutamate (PE/PPE) gene family, exclusive to pathogenic mycobacterium. Some of these proteins are known to play role in virulence and immune response modulation, but many are still uncharacterized. This study investigated the role of C-terminal region of Rv1039c (PPE15) in inducing mitochondrial perturbations and macrophage apoptosis. Our in-silico studies revealed the disordered, coiled, and hydrophobic C-terminal region in Rv1039c has similarity with C-terminal of mitochondria-targeting pro-apoptotic host proteins. Wild type Rv1039c and C-terminal deleted Rv1039c (Rv1039c-/-Cterm) recombinant proteins were purified and their M. smegmatis knock-in strains were constructed which were used for in-vitro experiments. Confocal microscopy showed localization of Rv1039c to mitochondria of PMA-differentiated THP1 macrophages; and reduced mitochondrial membrane depolarization and production of mitochondrial superoxides were observed in response to Rv1039c-/-Cterm in comparison to full-length Rv1039c. The C-terminal region of Rv1039c was found to activate caspases 3, 7 and 9 along with upregulated expression of pro-apoptotic genes like Bax and Bim. Rv1039c-/-Cterm also reduced the Cytochrome-C release from the mitochondria and the expression of AnnexinV/PI positive and TUNEL positive cells as compared to Rv1039c. Additionally, Rv1039c was observed to upregulate the TLR4-NF-κB-TNF-α signalling whereas the same was downregulated in response to Rv1039c-/-Cterm. These findings suggested that the C-terminal region of Rv1039c is a molecular mimic of pro-apoptotic host proteins which induce mitochondria-dependent macrophage apoptosis and evoke host immune response. These observations enhance our understanding about the role of PE/PPE proteins at host-pathogen interface.
    Language English
    Publishing date 2024-04-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1452360-7
    ISSN 1573-675X ; 1360-8185
    ISSN (online) 1573-675X
    ISSN 1360-8185
    DOI 10.1007/s10495-024-01965-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5178: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Drought stress in

    Saini, Sakshi / Sharma, Priyanka / Sharma, Jyoti / Pooja, Pooja / Sharma, Asha

    Physiology and molecular biology of plants : an international journal of functional plant biology

    2024  Volume 30, Issue 2, Page(s) 227–247

    Language English
    Publishing date 2024-02-27
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-024-01417-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Review on Microencapsulation as Method of Drug Delivery

    Chaturvedi Priyanka / Sharma Praveen

    BIO Web of Conferences, Vol 86, p

    2024  Volume 01033

    Abstract: Microencapsulation can be described as heavy, fluid or gaseous substance packaging engineering with thin polymeric coatings, creating small particles called microcapsules. Microencapsulation is very helpful to increase the solubility of drugs. For the ... ...

    Abstract Microencapsulation can be described as heavy, fluid or gaseous substance packaging engineering with thin polymeric coatings, creating small particles called microcapsules. Microencapsulation is very helpful to increase the solubility of drugs. For the drugs of BCS Class-II we use this technique which enables us to get more solubility and increase dissolution profile. This is a novel method of drug delivery. In future aspect we can use this technique in the foodindustry, beverages. A microencapsulation approach for the preparation of an intrauterine contraceptionsystem was alsosuggested. This technique is helpful to overcome poor solubility, low Bioavaibility and less stability.This method also gives more control over the drawback of conventional dosages form.
    Keywords microencapsulation ; bioavailability ; solubility ; novel drug delivery ; Microbiology ; QR1-502 ; Physiology ; QP1-981 ; Zoology ; QL1-991
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Preclinical models of atherosclerosis: An overview.

    Arya, Priyanka / Sharma, Vikram / Thapliyal, Surabhi / Sagar, Rahul / Singh, Priyanka

    Iranian journal of basic medical sciences

    2024  Volume 27, Issue 5, Page(s) 535–542

    Abstract: Atherosclerosis is a primary cause of illness and death globally and its mechanism is still unclear. Different animal models have been created to evaluate the progression of atherosclerosis, allowing researchers to carefully control the circumstances of ... ...

    Abstract Atherosclerosis is a primary cause of illness and death globally and its mechanism is still unclear. Different animal models have been created to evaluate the progression of atherosclerosis, allowing researchers to carefully control the circumstances of the experiment as well as the nutrition and environmental risk factors. To investigate the negative effects of various interventions, pathophysiological alterations might be generated utilizing genetic or pharmacological methods. These models' molecular and pathophysiological mechanisms have been clarified through experiments, and they have served as platforms for the creation of new drugs. Different models can be employed to address various research problems, each with its own benefits and drawbacks. In the current review study, various species of atherosclerosis models are discussed, along with the viability of using them in experiments.
    Language English
    Publishing date 2024-03-27
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2500485-2
    ISSN 2008-3874 ; 2008-3866
    ISSN (online) 2008-3874
    ISSN 2008-3866
    DOI 10.22038/IJBMS.2024.74352.16148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: PE_PGRS45 (Rv2615c) protein of Mycobacterium tuberculosis perturbs mitochondria of macrophages.

    Medha / Priyanka / Sharma, Sadhna / Sharma, Monika

    Immunology and cell biology

    2023  

    Abstract: The PE_PGRS proteins have coevolved with the antigenic ESX-V secretory system and are abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been characterized, and research suggests their role in organelle targeting, cell death pathways, ...

    Abstract The PE_PGRS proteins have coevolved with the antigenic ESX-V secretory system and are abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been characterized, and research suggests their role in organelle targeting, cell death pathways, calcium (Ca
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 284057-1
    ISSN 1440-1711 ; 0818-9641
    ISSN (online) 1440-1711
    ISSN 0818-9641
    DOI 10.1111/imcb.12677
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.175: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Experiences from a COVID-19 vaccination center at a tertiary care teaching hospital in Delhi, India: Challenges and solutions.

    Sharma, Priyanka / Pardeshi, Geeta

    Journal of emergency management (Weston, Mass.)

    2024  Volume 22, Issue 2, Page(s) 213–218

    Abstract: India began its nationwide coronavirus disease 2019 (COVID-19) vaccination program on January 16, 2021, in a phased manner. In this paper, we have discussed our experience at one of the COVID-19 vaccination centers in the country and have identified a ... ...

    Abstract India began its nationwide coronavirus disease 2019 (COVID-19) vaccination program on January 16, 2021, in a phased manner. In this paper, we have discussed our experience at one of the COVID-19 vaccination centers in the country and have identified a few of the major challenges and their implications. The guidelines for COVID-19 vaccination in the country were changing frequently, leading to ambiguity among the beneficiaries. Co-WIN software, used for program implementation, had some glitches, which caused dissatisfaction among the service providers and beneficiaries. Vaccine hesitancy and eagerness caused low vaccine uptake initially and overcrowding at vaccination centers later. Some of the vaccination centers had the potential to become hot spots for further spread of the virus due to insufficient infrastructure. The disparity in access to vaccines for the homeless and other vulnerable groups was another hurdle for adequate vaccination coverage. These challenges could have been addressed by pretesting the information technology platform, long-term planning with a vision for handling vaccine hesitancy and eagerness, strong communication systems, removing disparities in vaccine access, and maintaining uniformity in messages for frequently updating guidelines.
    MeSH term(s) Humans ; India ; COVID-19/prevention & control ; COVID-19 Vaccines ; SARS-CoV-2 ; Hospitals, Teaching ; Immunization Programs ; Vaccination Hesitancy/psychology ; Vaccination Hesitancy/statistics & numerical data ; Tertiary Care Centers ; Vaccination/statistics & numerical data ; Vaccination/psychology ; Vaccination Coverage/statistics & numerical data ; Health Services Accessibility
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2799989-0
    ISSN 1543-5865
    ISSN 1543-5865
    DOI 10.5055/jem.0822
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Highly fluorescent quinone-capped silver hydrosol for environmental remediation and sensing applications.

    Sahu, Mamta / Ganguly, Mainak / Sharma, Priyanka

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2024  Volume 311, Page(s) 123981

    Abstract: A metal-enhanced fluorescence was achieved from in situ-generated ... ...

    Abstract A metal-enhanced fluorescence was achieved from in situ-generated Ag
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2024.123981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 51/98: Show issues
    Z 1611 a: Show issues
    924/340: Show issues

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