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  1. Article ; Online: Necessity of pharmacist-driven nonprescription telehealth consult services in the era of COVID-19.

    Yemm, Kristyn E / Arnall, Justin R / Cowgill, Nicole A

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    2020  Volume 77, Issue 15, Page(s) 1188

    MeSH term(s) COVID-19 ; Coronavirus Infections/therapy ; Humans ; Pandemics ; Pharmacists ; Pneumonia, Viral/therapy ; Referral and Consultation/organization & administration ; Telemedicine/organization & administration
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country England
    Document type Letter
    ZDB-ID 1224627-x
    ISSN 1535-2900 ; 1079-2082
    ISSN (online) 1535-2900
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxaa162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Necessity of pharmacist-driven nonprescription telehealth consult services in the era of COVID-19

    Yemm, Kristyn E / Arnall, Justin R / Cowgill, Nicole A

    American Journal of Health-System Pharmacy

    2020  Volume 77, Issue 15, Page(s) 1188–1188

    Keywords Health Policy ; Pharmacology ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 1224627-x
    ISSN 1079-2082
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxaa162
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Renal toxicity with liposomal doxorubicin in metastatic breast cancer.

    Yemm, Kristyn E / Alwan, Laura M / Malik, A Bilal / Salazar, Lupe G

    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

    2018  Volume 25, Issue 7, Page(s) 1738–1742

    Abstract: There is no preferred treatment option for metastatic breast cancer; therefore, treatment should provide palliation, prolong survival, control symptoms, and improve quality of life. Liposomal doxorubicin formulations have been shown to have less alopecia, ...

    Abstract There is no preferred treatment option for metastatic breast cancer; therefore, treatment should provide palliation, prolong survival, control symptoms, and improve quality of life. Liposomal doxorubicin formulations have been shown to have less alopecia, nausea, vomiting, and myelosuppression than traditional doxorubicin, but more skin toxicities and infusion reactions. Prolonged use of liposomal doxorubicin may be associated with unrecognized or less well-defined toxicities. We report a case of acute kidney injury and progressively worsening chronic kidney disease necessitating dialysis in a patient who received prolonged therapy with liposomal doxorubicin for treatment of metastatic breast cancer. This case report should give caution to providers considering prolonged use of liposomal doxorubicin in the metastatic breast cancer setting as we observed sustained renal toxicity, long past the cessation of treatment.
    MeSH term(s) Antibiotics, Antineoplastic/administration & dosage ; Breast Neoplasms/drug therapy ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Doxorubicin/analogs & derivatives ; Female ; Humans ; Middle Aged ; Polyethylene Glycols/administration & dosage ; Polyethylene Glycols/adverse effects ; Quality of Life
    Chemical Substances Antibiotics, Antineoplastic ; liposomal doxorubicin ; Polyethylene Glycols (3WJQ0SDW1A) ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2018-08-31
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1330764-2
    ISSN 1477-092X ; 1078-1552
    ISSN (online) 1477-092X
    ISSN 1078-1552
    DOI 10.1177/1078155218798157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A comparison of levofloxacin and oral third-generation cephalosporins as antibacterial prophylaxis in acute leukaemia patients during chemotherapy-induced neutropenia.

    Yemm, Kristyn E / Barreto, Jason N / Mara, Kristin C / Dierkhising, Ross A / Gangat, Naseema / Tosh, Pritish K

    The Journal of antimicrobial chemotherapy

    2017  Volume 73, Issue 1, Page(s) 204–211

    Abstract: Background: There is demonstrated benefit with fluoroquinolones as infection prophylaxis in neutropenic patients; however, side effects, drug interactions and increasing resistance necessitate investigation of alternative therapies.: Objectives: To ... ...

    Abstract Background: There is demonstrated benefit with fluoroquinolones as infection prophylaxis in neutropenic patients; however, side effects, drug interactions and increasing resistance necessitate investigation of alternative therapies.
    Objectives: To compare the incidence of febrile neutropenia in high-risk patients with haematological malignancy receiving a fluoroquinolone with those receiving an oral third-generation cephalosporin (OTGC) as antibacterial prophylaxis during chemotherapy-induced neutropenia.
    Methods: A retrospective, matched, single-centre study comparing clinical and microbiological outcomes in acute leukaemia patients receiving fluoroquinolones versus OTGCs as antibacterial prophylaxis after chemotherapy.
    Results: A total of 120 patients (levofloxacin n = 80, OTGC n = 40) were included and matched. The 30 day incidence of febrile neutropenia was 89.7% (95% CI = 82.4-93.9). The rates of febrile neutropenia were similar between antimicrobials (OTGC versus levofloxacin HR = 0.90, 95% CI = 0.54-1.52, P = 0.70). The most frequent site of infection was the bloodstream (line related) (n = 24, 62%) and the majority (n = 28, 72%) of infections were caused by Gram-positive organisms. Groups were similar in terms of site of infection (P = 0.91) and morphology of recovered microorganisms (P = 0.74). There were significantly more cultures positive for Enterobacter spp. in the OTGC group (P = 0.043). Three patients died during follow-up (from first dose up to 30 days after the last dose) (30 day survival = 99.2%, 95% CI = 97.5-100), with only two of the reported deaths attributable to infection.
    Conclusions: These findings demonstrate comparable rates of febrile neutropenia and culture positivity with an increase in cultures positive for Enterobacter spp. when OTGCs are compared with levofloxacin for antibacterial prophylaxis during chemotherapy-induced neutropenia. Further prospective, randomized investigation is warranted.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis/methods ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Bacteremia/prevention & control ; Cephalosporins/therapeutic use ; Febrile Neutropenia/chemically induced ; Female ; Hematologic Neoplasms/drug therapy ; Humans ; Leukemia/drug therapy ; Levofloxacin/therapeutic use ; Male ; Middle Aged ; Retrospective Studies ; Young Adult
    Chemical Substances Anti-Bacterial Agents ; Antineoplastic Agents ; Cephalosporins ; Levofloxacin (6GNT3Y5LMF)
    Language English
    Publishing date 2017-10-16
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkx338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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