LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 1575

Search options

  1. Article ; Online: Evidence for novelty reward cross-cueing in the odor span task in rats: implications for odor-based reward-motivated tasks.

    Onofrychuk, Timothy J / Glass, Aiden E / Greba, Quentin / Howland, John G

    Learning & memory (Cold Spring Harbor, N.Y.)

    2024  Volume 31, Issue 1-2

    Abstract: The odor span task (OST) infers working memory capacity (WMC) by requiring rodents to discriminate between previously presented and session-novel odors to obtain a hidden food reward. Here, rats' responses to session-novel odors and food rewards were ... ...

    Abstract The odor span task (OST) infers working memory capacity (WMC) by requiring rodents to discriminate between previously presented and session-novel odors to obtain a hidden food reward. Here, rats' responses to session-novel odors and food rewards were assessed to determine whether rats use mitigating strategies in the OST. Rats accurately responded to session-novel odors but also reliably responded to the food reward alone and performed at chance when both a session-novel odor and food reward were presented in separate locations. The inclusion of unscented sand in the cups holding the food reward significantly reduced the rats' responses to the food reward alone. Collectively, these results demonstrate the need for rigorous tests of potential mitigating strategies and hold wide implications for rodent odor discrimination-based behavioral tasks.
    MeSH term(s) Rats ; Animals ; Odorants ; Memory, Short-Term/physiology ; Cues ; Motivation ; Reward ; Smell/physiology
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1204777-6
    ISSN 1549-5485 ; 1072-0502
    ISSN (online) 1549-5485
    ISSN 1072-0502
    DOI 10.1101/lm.053871.123
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: A fuzzy logic based explicit declustering technique.

    Muhammad, Khan / Glass, Hylke J

    Heliyon

    2023  Volume 9, Issue 6, Page(s) e16817

    Abstract: ... for conducting conditional simulations to model uncertainty of spatially distributed attributes, e.g. geochemical ... such as cell declustering do not consider grade clustering, i.e., the similarity of measured variables ...

    Abstract During the spatial estimation of geoscience resource variables, the quantity or quality of minerals and hydrocarbons can be represented by a broad range of properties, including geochemical, geotechnical, or other physical measures. Preferential sampling within the region of interest causes biased global parameters due to clustered sampling patterns. Unbiased sample distribution is essential for conducting conditional simulations to model uncertainty of spatially distributed attributes, e.g. geochemical content of metal or porosity. Therefore, declustering procedures are applied during resource estimation to estimate an unbiased statistical distribution of the measured variables. Traditional techniques such as cell declustering do not consider grade clustering, i.e., the similarity of measured variables within a spatially clustered neighbourhood. This paper presents a declustering technique that explicitly accounts for spatial clustering and the similarity of measured samples' attributes within these spatially clustered samples. In the proposed method, samples were first classified explicitly into spatial and geochemical (grade) clusters using the Fuzzy c-means algorithm. Declustering weights were derived using the Mamdani based Fuzzy Inference System using various T-norm operations. The technique was applied to the publicly available GSLib and Walker Lake datasets. It was shown that the proposed scheme produced more accurate results than those obtained with the traditional declustering technique.
    Language English
    Publishing date 2023-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e16817
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: The anterior retrosplenial cortex is required for short-term object in place recognition memory retrieval: Role of ionotropic glutamate receptors in male and female Long-Evans rats.

    McElroy, Dan L / Sabir, Hassaan / Glass, Aiden E / Greba, Quentin / Howland, John G

    The European journal of neuroscience

    2024  

    Abstract: ... learning phases (i.e., encoding and retrieval). Additionally, sex differences are observed in performance ...

    Abstract The anterior retrosplenial cortex (aRSC) integrates multimodal sensory information into cohesive associative recognition memories. Little is known about how information is integrated during different learning phases (i.e., encoding and retrieval). Additionally, sex differences are observed in performance of some visuospatial memory tasks; however, inconsistent findings warrant more research. We conducted three experiments using the 1-h delay object-in-place (1-h OiP) test to assess recognition memory retrieval in male and female Long-Evans rats. (i) We found both sexes performed equally in three repeated 1-h OiP test sessions. (ii) We showed infusions of a mixture of muscimol/baclofen (GABA
    Language English
    Publishing date 2024-02-27
    Publishing country France
    Document type Journal Article
    ZDB-ID 645180-9
    ISSN 1460-9568 ; 0953-816X
    ISSN (online) 1460-9568
    ISSN 0953-816X
    DOI 10.1111/ejn.16284
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Chloroplast genome evolution and phylogeny of the early-diverging charophycean green algae with a focus on the Klebsormidiophyceae and Streptofilum.

    Glass, Sarah E / McCourt, Richard M / Gottschalk, Stephen D / Lewis, Louise A / Karol, Kenneth G

    Journal of phycology

    2023  Volume 59, Issue 6, Page(s) 1133–1146

    Abstract: The Klebsormidiophyceae are a class of green microalgae observed globally in both freshwater and terrestrial habitats. Morphology-based classification schemes of this class have been shown to be inadequate due to the simple morphology of these algae, the ...

    Abstract The Klebsormidiophyceae are a class of green microalgae observed globally in both freshwater and terrestrial habitats. Morphology-based classification schemes of this class have been shown to be inadequate due to the simple morphology of these algae, the tendency of morphology to vary in culture versus field conditions, and rampant morphological homoplasy. Molecular studies revealing cryptic diversity have renewed interest in this group. We sequenced the complete chloroplast genomes of a broad series of taxa spanning the known taxonomic breadth of this class. We also sequenced the chloroplast genomes of three strains of Streptofilum, a recently discovered green algal lineage with close affinity to the Klebsormidiophyceae. Our results affirm the previously hypothesized polyphyly of the genus Klebsormidium as well as the polyphyly of the nominal species in this genus, K. flaccidum. Furthermore, plastome sequences strongly support the status of Streptofilum as a distinct, early-diverging lineage of charophytic algae sister to a clade comprising Klebsormidiophyceae plus Phragmoplastophyta. We also uncovered major structural alterations in the chloroplast genomes of species in Klebsormidium that have broad implications regarding the underlying mechanisms of chloroplast genome evolution.
    MeSH term(s) Phylogeny ; Genome, Chloroplast ; Chlorophyta/genetics ; Evolution, Molecular
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 281226-5
    ISSN 1529-8817 ; 0022-3646
    ISSN (online) 1529-8817
    ISSN 0022-3646
    DOI 10.1111/jpy.13359
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Correction: Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice.

    Henn, Rosemary E / Elzinga, Sarah E / Glass, Emily / Parent, Rachel / Guo, Kai / Allouch, Adam M / Mendelson, Faye E / Hayes, John / Webber-Davis, Ian / Murphy, Geoffery G / Hur, Junguk / Feldman, Eva L

    Immunity & ageing : I & A

    2024  Volume 21, Issue 1, Page(s) 16

    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2168941-6
    ISSN 1742-4933
    ISSN 1742-4933
    DOI 10.1186/s12979-024-00422-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: A systematic review of risk factors associated with depression and anxiety in cancer patients.

    Ikhile, Deborah / Ford, Elizabeth / Glass, Devyn / Gremesty, Georgie / van Marwijk, Harm

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0296892

    Abstract: Depression and anxiety are common comorbid conditions associated with cancer, however the risk factors responsible for the onset of depression and anxiety in cancer patients are not fully understood. Also, there is little clarity on how these factors may ...

    Abstract Depression and anxiety are common comorbid conditions associated with cancer, however the risk factors responsible for the onset of depression and anxiety in cancer patients are not fully understood. Also, there is little clarity on how these factors may vary across the cancer phases: diagnosis, treatment and depression. We aimed to systematically understand and synthesise the risk factors associated with depression and anxiety during cancer diagnosis, treatment and survivorship. We focused our review on primary and community settings as these are likely settings where longer term cancer care is provided. We conducted a systematic search on PubMed, PsychInfo, Scopus, and EThOS following the PRISMA guidelines. We included cross-sectional and longitudinal studies which assessed the risk factors for depression and anxiety in adult cancer patients. Quality assessment was undertaken using the Newcastle-Ottawa assessment checklists. The quality of each study was further rated using the Agency for Healthcare Research and Quality Standards. Our search yielded 2645 papers, 21 of these were eligible for inclusion. Studies were heterogenous in terms of their characteristics, risk factors and outcomes measured. A total of 32 risk factors were associated with depression and anxiety. We clustered these risk factors into four domains using an expanded biopsychosocial model of health: cancer-specific, biological, psychological and social risk factors. The cancer-specific risk factors domain was associated with the diagnosis, treatment and survivorship phases. Multifactorial risk factors are associated with the onset of depression and anxiety in cancer patients. These risk factors vary across cancer journey and depend on factors such as type of cancer and individual profile of the patients. Our findings have potential applications for risk stratification in primary care and highlight the need for a personalised approach to psychological care provision, as part of cancer care.
    MeSH term(s) Adult ; Humans ; Depression/complications ; Depression/epidemiology ; Cross-Sectional Studies ; Anxiety/complications ; Anxiety/epidemiology ; Anxiety Disorders ; Neoplasms/complications ; Neoplasms/epidemiology ; Neoplasms/therapy
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0296892
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Pharmacists' roles in assisted reproductive technology.

    Mackay, Amanda M / Taylor, Selina M / Glass, Beverley D

    Exploratory research in clinical and social pharmacy

    2023  Volume 12, Page(s) 100376

    Abstract: ... specialisation status and geographical location (e.g., self-efficacy), whereas others were consistent (e.g ...

    Abstract Background: The global issue of infertility has prompted an increased reliance on Assisted Reproductive Technology (ART) for conception. In Australia, patients have previously accessed ART medications through specialist clinics, however recently due to modifications in ART medication subsidisation, community pharmacists now dispense and counsel patients on ART medications. Patients residing in rural and remote locations face challenges in accessing fertility clinics, which are primarily located in metropolitan and large regional cities.
    Objective: To investigate the perceived role, experience, confidence, and training requirements that pharmacists have in relation to providing ART medications and counselling to patients.
    Methods: Purposive sampling related to location of practice, pharmacist experience with ART and self-classification as an ART specialist was used to recruit 19 Australian pharmacists from rural, remote, large regional, and metropolitan areas, who participated in semi-structured interviews based on the Consolidated Framework for Implementation Research (CFIR). Interview transcriptions were transcribed, imported into NVivo, analysed using thematic analysis and mapped to CFIR domains and constructs.
    Results: Of the nineteen pharmacists interviewed, six were from rural and remote areas and thirteen were from metropolitan or large regional areas. Eight participants perceived themselves as specialist pharmacists in ART, all of which were in metropolitan or large regional locations. Three CFIR domains were identified as relevant for this study, which were further developed, with data mapped to eleven constructs under those domains. Emergent themes were identified that contributed to the pharmacist role including patient needs, external policies, fertility clinics, pharmacist experience and training, procuring ART, and the personal attributes of participants. Some constructs and themes differed between participants dependent on self-reported specialisation status and geographical location (e.g., self-efficacy), whereas others were consistent (e.g., knowledge and belief about the intervention). Pharmacists considered their role not to be limited to the supply and counselling of medication, but to also involve a support role for patients undergoing an emotionally difficult and sensitive journey, without guaranteed success.
    Conclusion: This study reveals the diverse role of Australian pharmacists in ART, influenced by location, experience, and confidence. Pharmacists have an important role to play in reducing barriers to ART access by offering fertility education, addressing concerns, providing medications and counselling, and monitoring patient well-being, improving outcomes for this cohort of patients particularly in rural and remote areas.
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ISSN 2667-2766
    ISSN (online) 2667-2766
    DOI 10.1016/j.rcsop.2023.100376
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: A fuzzy logic based explicit declustering technique

    Khan Muhammad / Hylke J. Glass

    Heliyon, Vol 9, Iss 6, Pp e16817- (2023)

    2023  

    Abstract: ... for conducting conditional simulations to model uncertainty of spatially distributed attributes, e.g. geochemical ... such as cell declustering do not consider grade clustering, i.e., the similarity of measured variables ...

    Abstract During the spatial estimation of geoscience resource variables, the quantity or quality of minerals and hydrocarbons can be represented by a broad range of properties, including geochemical, geotechnical, or other physical measures. Preferential sampling within the region of interest causes biased global parameters due to clustered sampling patterns. Unbiased sample distribution is essential for conducting conditional simulations to model uncertainty of spatially distributed attributes, e.g. geochemical content of metal or porosity. Therefore, declustering procedures are applied during resource estimation to estimate an unbiased statistical distribution of the measured variables. Traditional techniques such as cell declustering do not consider grade clustering, i.e., the similarity of measured variables within a spatially clustered neighbourhood. This paper presents a declustering technique that explicitly accounts for spatial clustering and the similarity of measured samples' attributes within these spatially clustered samples. In the proposed method, samples were first classified explicitly into spatial and geochemical (grade) clusters using the Fuzzy c-means algorithm. Declustering weights were derived using the Mamdani based Fuzzy Inference System using various T-norm operations. The technique was applied to the publicly available GSLib and Walker Lake datasets. It was shown that the proposed scheme produced more accurate results than those obtained with the traditional declustering technique.
    Keywords Declustering ; Fuzzy-c-means ; Fuzzy logic ; Global estimation ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 310 ; 006
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Snapshot of COVID-19 superinfections in Marseille hospitals: where are the common pathogens?

    Le Glass, Elisabeth / Raoult, Didier / Dubourg, Grégory

    Epidemiology and infection

    2022  Volume 150, Page(s) e195

    Abstract: Episodes of bacterial superinfections have been well identified for several respiratory viruses, notably influenza. In this retrospective study, we compared the frequency of superinfections in COVID-19 patients to those found in influenza-positive ... ...

    Abstract Episodes of bacterial superinfections have been well identified for several respiratory viruses, notably influenza. In this retrospective study, we compared the frequency of superinfections in COVID-19 patients to those found in influenza-positive patients, and to controls without viral infection. We included 42 468 patients who had been diagnosed with COVID-19 and 266 261 subjects who had tested COVID-19 negative between 26 February 2020 and 1 May 2021. In addition, 4059 patients were included who had tested positive for the influenza virus between 1 January 2017 and 31 December 2019. Bacterial infections in COVID-19 patients were more frequently healthcare-associated, and acquired in ICUs, were associated with longer ICU stays, and occurred in older and male patients when compared to controls and to influenza patients (
    MeSH term(s) Humans ; Male ; Aged ; COVID-19/epidemiology ; Superinfection ; Retrospective Studies ; Influenza, Human ; Escherichia coli ; Bacterial Infections/epidemiology ; Hospitals ; Bacteremia/epidemiology
    Language English
    Publishing date 2022-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268822001704
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Electrogelation: Controlled Fast Formation of Micrometer-Thick Films from Low-Molecular Weight Hydrogelators.

    Raßmann, Nadine / Weber, Melina / Glaß, Roman E J / Kreger, Klaus / Helfricht, Nicolas / Schmidt, Hans-Werner / Papastavrou, Georg

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 48, Page(s) 17190–17200

    Abstract: The controlled electrochemical deposition of hydrogels from low-molecular weight hydrogelators (LMWHGs) allows for the defined formation of thin films on electrodes. Here, the deposition of fibrillar networks consisting ... ...

    Abstract The controlled electrochemical deposition of hydrogels from low-molecular weight hydrogelators (LMWHGs) allows for the defined formation of thin films on electrodes. Here, the deposition of fibrillar networks consisting of
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02270
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top