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  1. Article ; Online: Anti-Aging in

    Zhang, Xue / Chen, Qi / Chen, Linzhen / Chen, Xiaolu / Ma, Zhiqiang

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 6

    Abstract: Polygonatum ... ...

    Abstract Polygonatum cyrtonema
    MeSH term(s) Animals ; Caenorhabditis elegans/metabolism ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Polygonatum ; Aging ; Polysaccharides/pharmacology ; Polysaccharides/metabolism ; Superoxide Dismutase/metabolism
    Chemical Substances Antioxidants ; Polysaccharides ; Superoxide Dismutase (EC 1.15.1.1)
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29061276
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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  2. Article ; Online: Overview of chicken embryo genes related to sex differentiation.

    Luo, Xiaolu / Guo, Jiancheng / Zhang, Jiahang / Ma, Zheng / Li, Hua

    PeerJ

    2024  Volume 12, Page(s) e17072

    Abstract: Sex determination in chickens at an early embryonic stage has been a longstanding challenge in poultry production due to the unique ZZ:ZW sex chromosome system and various influencing factors. This review has summarized the genes related to the sex ... ...

    Abstract Sex determination in chickens at an early embryonic stage has been a longstanding challenge in poultry production due to the unique ZZ:ZW sex chromosome system and various influencing factors. This review has summarized the genes related to the sex differentiation of chicken early embryos (mainly
    MeSH term(s) Chick Embryo ; Animals ; Chickens/genetics ; Sex Differentiation/genetics ; Sex Determination Processes/genetics ; Sex Chromosomes
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.17072
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  3. Article: Targeting endoplasmic reticulum stress signaling in ovarian cancer therapy.

    Yan, Tianqing / Ma, Xiaolu / Guo, Lin / Lu, Renquan

    Cancer biology & medicine

    2023  Volume 20, Issue 10

    Abstract: The endoplasmic reticulum (ER), an organelle present in various eukaryotic cells, is responsible for intracellular protein synthesis, post-translational modification, and folding and transport, as well as the regulation of lipid and steroid metabolism ... ...

    Abstract The endoplasmic reticulum (ER), an organelle present in various eukaryotic cells, is responsible for intracellular protein synthesis, post-translational modification, and folding and transport, as well as the regulation of lipid and steroid metabolism and Ca
    MeSH term(s) Female ; Humans ; Endoplasmic Reticulum Stress/physiology ; Unfolded Protein Response ; Signal Transduction ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/pathology ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum/pathology ; Tumor Microenvironment
    Language English
    Publishing date 2023-10-10
    Publishing country China
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2676322-9
    ISSN 2095-3941
    ISSN 2095-3941
    DOI 10.20892/j.issn.2095-3941.2023.0232
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  4. Article ; Online: Correlation between S100A7 and immune characteristics, methylation, tumor stemness and tumor heterogeneity in pan-cancer and its role in chemotherapy resistance in breast cancer.

    Li, Yilun / Yang, Xiaolu / Jin, Tingting / Li, Qiuli / Li, Xiaolong / Ma, Li

    Aging

    2024  Volume 16, Issue 6, Page(s) 5581–5600

    Abstract: Objective: To explore the relationships between : Methods: TCGA-BRCA and TCGA-PANCANCER RNA-seq data and clinical follow-up survival data were collected from the University of California Santa Cruz database. Survival analyses were performed to ... ...

    Abstract Objective: To explore the relationships between
    Methods: TCGA-BRCA and TCGA-PANCANCER RNA-seq data and clinical follow-up survival data were collected from the University of California Santa Cruz database. Survival analyses were performed to explore the relationship between
    Results: S100A7
    Conclusion: High
    MeSH term(s) Animals ; Adjuvants, Immunologic ; Biological Assay ; Mammary Neoplasms, Animal ; Methylation ; Protein Processing, Post-Translational ; Humans
    Chemical Substances Adjuvants, Immunologic ; S100A7 protein, human
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.205665
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  5. Article: Therapeutic hypothermia can cause non-infective C-reactive protein elevating.

    Wang, Xiaohong / Shi, Liping / Wang, Chenhong / Ma, Xiaolu

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1157417

    Abstract: Objective: To analyze the relationship between therapeutic hypothermia (TH) and whole blood high-sensitivity C-reactive protein (hs-CRP) in neonates with hypoxic-ischemic encephalopathy (HIE).: Method: Retrospective analysis was made on the clinical ... ...

    Abstract Objective: To analyze the relationship between therapeutic hypothermia (TH) and whole blood high-sensitivity C-reactive protein (hs-CRP) in neonates with hypoxic-ischemic encephalopathy (HIE).
    Method: Retrospective analysis was made on the clinical data of hospitalized infants diagnosed with asphyxia in our neonatal intensive care unit from January 2014 to June 2021. According to whether TH was performed, they were divided into two groups, the control group (missed the time in other hospitals and did not receive TH) and the treatment group (TH group). In their first ten days, analysis was made on the hs-CRP, white blood cell (WBC) count, neutrophil percentage, platelet count (PLT), and brain MRI. The correlation analysis was carried out based on the severity of brain injury displayed by the brain MRI and the time of hs-CRP elevation to summarize the relationship between TH and the time of hs-CRP elevation and the severity of HIE.
    Results: 83 infants were included, 28 in the control group and 55 in the TH group. After birth, 33 infants (60.0%) in the TH group and 2 patients (7.1%) in the control group had elevated hs-CRP, which was statistically significant (
    Conclusions: TH can increase the blood hs-CRP of HIE neonates, and the probability of its occurrence is related to the severity of HIE. The heavier the HIE, the higher the risk of hs-CRP elevation after TH; The hs-CRP elevation has little to do with infection, and it doesn't recommend using antibiotics actively.
    Language English
    Publishing date 2023-04-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1157417
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  6. Article: [Matrix stiffening related lncRNA SNHG8 regulates chemosensitivity of ovarian cancer].

    Cheng, Zina / Ma, Xiaolu / Zhang, Quanyou / Chen, Weiyi

    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi

    2023  Volume 40, Issue 1, Page(s) 87–94

    Abstract: Extracellular matrix (ECM) has been implicated in tumor progress and chemosensitivity. Ovarian cancer brings a great threat to the health of women with a significant feature of high mortality and poor prognosis. However, the potential significance of ... ...

    Abstract Extracellular matrix (ECM) has been implicated in tumor progress and chemosensitivity. Ovarian cancer brings a great threat to the health of women with a significant feature of high mortality and poor prognosis. However, the potential significance of matrix stiffness in the pattern of long non-coding RNAs (lncRNAs) expression and ovarian cancer drug sensitivity is still largely unkown. Here, based on RNA-seq data of ovarian cancer cell cultured on substrates with different stiffness, we found that a great amount of lncRNAs were upregulated in stiff group, whereas SNHG8 was significantly downregulated, which was further verified in ovarian cancer cells cultured on polydimethylsiloxane (PDMS) hydrogel. Knockdown of SNHG8 led to an impaired efficiency of homologous repair, and decreased cellular sensitivity to both etoposide and cisplatin. Meanwhile, the results of the GEPIA analysis indicated that the expression of SNHG8 was significantly decreased in ovarian cancer tissues, which was negatively correlated with the overall survival of patients with ovarian cancer. In conclusion, matrix stiffening related lncRNA SNHG8 is closely related to chemosensitivity and prognosis of ovarian cancer, which might be a novel molecular marker for chemotherapy drug instruction and prognosis prediction.
    MeSH term(s) Female ; Humans ; Cisplatin/pharmacology ; Elasticity/physiology ; Etoposide ; Extracellular Matrix/genetics ; Extracellular Matrix/physiology ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Etoposide (6PLQ3CP4P3) ; long noncoding RNA SNHG8, human ; RNA, Long Noncoding
    Language Chinese
    Publishing date 2023-03-02
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2576847-5
    ISSN 1001-5515
    ISSN 1001-5515
    DOI 10.7507/1001-5515.202205038
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6887: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Generation of an induced pluripotent stem cell line (SYSUSCi004-A) from a patient with Infantile Malignant Osteopetrosis.

    Fang, Rui / Guo, Xiaolu / Feng, Jianqi / Chen, Qiumin / Wang, Tao / Ma, Jianping

    Stem cell research

    2024  Volume 76, Page(s) 103330

    Abstract: Infantile Malignant Osteopetrosis (IMO) is a rare, severe autosomal recessive form of osteopetrosis. Here, the peripheral blood mononuclear cells (PBMCs) extracted from a patient with IMO carrying a compound heterozygous mutation in T cell immune ... ...

    Abstract Infantile Malignant Osteopetrosis (IMO) is a rare, severe autosomal recessive form of osteopetrosis. Here, the peripheral blood mononuclear cells (PBMCs) extracted from a patient with IMO carrying a compound heterozygous mutation in T cell immune regulator 1, ATPase H + transporting V0 subunit a3 (TCIRG1) gene (c.242delC; c.1114C > T) were successfully reprogrammed using Sendai virus encoding the four Yamanaka factors. The generated hiPSCs, IMO-hiPSCs, displayed typical embryonic stem cell-like morphology and were verified by expression of pluripotency markers such as OCT4, SOX2, NANOG, TRA-1-60 and SSEA4, as well as in vivo and in vitro differentiation into derivatives of three germ layers.
    MeSH term(s) Humans ; Induced Pluripotent Stem Cells/metabolism ; Osteopetrosis/metabolism ; Leukocytes, Mononuclear/metabolism ; Mutation ; Genes, Homeobox ; Cell Differentiation ; Vacuolar Proton-Translocating ATPases/genetics
    Chemical Substances TCIRG1 protein, human ; Vacuolar Proton-Translocating ATPases (EC 3.6.1.-)
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393143-7
    ISSN 1876-7753 ; 1873-5061
    ISSN (online) 1876-7753
    ISSN 1873-5061
    DOI 10.1016/j.scr.2024.103330
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  8. Article ; Online: Macrocycle γ-Cyclodextrin Confined Polymeric Chromophore Ultralong Phosphorescence Energy Transfer.

    Ma, Xin-Kun / Cheng, Qingwen / Zhou, Xiaolu / Liu, Yu

    JACS Au

    2023  Volume 3, Issue 7, Page(s) 2036–2043

    Abstract: A multicolor persistent luminescence solid polymeric system based on macrocycle-confined phosphorescence energy transfer was constructed with γ-cyclodextrin (γ-CD) and poly(vinyl alcohol) modified by triphenylene derivative (TP-PVA). Attributed to the ... ...

    Abstract A multicolor persistent luminescence solid polymeric system based on macrocycle-confined phosphorescence energy transfer was constructed with γ-cyclodextrin (γ-CD) and poly(vinyl alcohol) modified by triphenylene derivative (TP-PVA). Attributed to the fact that macrocycles effectively suppress the aggregation of guests and form a rigid environment via coassembling with the polymer, the phosphorescence lifetime of the yielded polymeric films is prolonged from 0.22 to 5.84 s, accompanied by a visible afterglow of more than 1 min. Furthermore, upon doping with several commercial dyes, full-color afterglow emissions with a duration of more than 50 s are realized through phosphorescence energy transfer. Notably, the multicolor-emitting-afterglow materials are successfully exploited for noctilucent lighting and anticounterfeiting ink.
    Language English
    Publishing date 2023-07-11
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3704
    ISSN (online) 2691-3704
    DOI 10.1021/jacsau.3c00255
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  9. Article ; Online: Characterization of the complete chloroplast genome of

    Lu, Yin / Ma, Qing / Xu, Xiaolu / Wang, Zhimin / Andrie, Ivanets / Savitskaya, Tatsiana / Yuzuak, Seyit

    Mitochondrial DNA. Part B, Resources

    2022  Volume 7, Issue 7, Page(s) 1213–1215

    Abstract: Elaeagnus ... ...

    Abstract Elaeagnus pungens
    Language English
    Publishing date 2022-07-04
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2022.2090291
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  10. Article ; Online: Comparative genomics reveals intraspecific divergence of

    Liu, Rui / Ma, Liyuan / Wang, Hongmei / Liu, Deng / Lu, Xiaolu / Huang, Xinping / Huang, Shanshan / Liu, Xueduan

    Microbial genomics

    2023  Volume 9, Issue 6

    Abstract: Acidithiobacillus ... ...

    Abstract Acidithiobacillus ferrooxidans
    MeSH term(s) Acidithiobacillus/genetics ; Acidithiobacillus/metabolism ; Genomics/methods ; Iron/metabolism ; Adaptation, Physiological/genetics
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2835258-0
    ISSN 2057-5858 ; 2057-5858
    ISSN (online) 2057-5858
    ISSN 2057-5858
    DOI 10.1099/mgen.0.001038
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