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  1. Article ; Online: JACC Focus Seminar on Mechanical Complications of Acute Myocardial Infarction.

    Moreno, Pedro R / Fuster, Valentin

    Journal of the American College of Cardiology

    2024  Volume 83, Issue 18, Page(s) 1775–1778

    MeSH term(s) Humans ; Myocardial Infarction/complications
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article ; Review ; Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2024.03.414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Right Ventricular Myocardial Infarction-A Tale of Two Ventricles: JACC Focus Seminar 1/5.

    Goldstein, James A / Lerakis, Stamatios / Moreno, Pedro R

    Journal of the American College of Cardiology

    2024  Volume 83, Issue 18, Page(s) 1779–1798

    Abstract: Right ventricular infarction (RVI) complicates 50% of cases of acute inferior ST-segment elevation myocardial infarction, and is associated with high in-hospital morbidity and mortality. Ischemic right ventricular (RV) systolic dysfunction decreases left ...

    Abstract Right ventricular infarction (RVI) complicates 50% of cases of acute inferior ST-segment elevation myocardial infarction, and is associated with high in-hospital morbidity and mortality. Ischemic right ventricular (RV) systolic dysfunction decreases left ventricular preload delivery, resulting in low-output hypotension with clear lungs, and disproportionate right heart failure. RV systolic performance is generated by left ventricular contractile contributions mediated by the septum. Augmented right atrial contraction optimizes RV performance, whereas very proximal occlusions induce right atrial ischemia exacerbating hemodynamic compromise. RVI is associated with vagal mediated bradyarrhythmias, both during acute occlusion and abruptly with reperfusion. The ischemic dilated RV is also prone to malignant ventricular arrhythmias. Nevertheless, RV is remarkably resistant to infarction. Reperfusion facilitates RV recovery, even after prolonged occlusion and in patients with severe shock. However, in some cases hemodynamic compromise persists, necessitating pharmacological and mechanical circulatory support with dedicated RV assist devices as a "bridge to recovery."
    MeSH term(s) Humans ; Ventricular Dysfunction, Right/physiopathology ; Ventricular Dysfunction, Right/etiology ; Heart Ventricles/physiopathology ; Myocardial Infarction/physiopathology
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.09.839
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of Severe Mitral Regurgitation in Patients With Acute Myocardial Infarction: JACC Focus Seminar 2/5.

    Estévez-Loureiro, Rodrigo / Lorusso, Roberto / Taramasso, Maurizio / Torregrossa, Gianluca / Kini, Annapoorna / Moreno, Pedro R

    Journal of the American College of Cardiology

    2024  Volume 83, Issue 18, Page(s) 1799–1817

    Abstract: Severe acute mitral regurgitation after myocardial infarction includes partial and complete papillary muscle rupture or functional mitral regurgitation. Although its incidence is <1%, mitral regurgitation after acute myocardial infarction frequently ... ...

    Abstract Severe acute mitral regurgitation after myocardial infarction includes partial and complete papillary muscle rupture or functional mitral regurgitation. Although its incidence is <1%, mitral regurgitation after acute myocardial infarction frequently causes hemodynamic instability, pulmonary edema, and cardiogenic shock. Medical management has the worst prognosis, and mortality has not changed in decades. Surgery represents the gold standard, but it is associated with high rates of morbidity and mortality. Recently, transcatheter interventions have opened a new door for management that may improve survival. Mechanical circulatory support restores vital organ perfusion and offers the opportunity for a steadier surgical repair. This review focuses on the diagnosis and the interventional management, both surgical and transcatheter, with a glance on future perspectives to enhance patient management and eventually decrease mortality.
    MeSH term(s) Humans ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/surgery ; Mitral Valve Insufficiency/complications ; Mitral Valve Insufficiency/therapy ; Myocardial Infarction/complications ; Myocardial Infarction/therapy ; Severity of Illness Index ; Cardiac Catheterization/methods ; Disease Management
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.09.840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Characterization of

    de Oliveira, Carolina H / Moreno, Luisa Z / Cardoso, Pedro H M / Silva, Ana Paula S / Gomes, Vasco T M / Barbosa, Mikaela R F / Balian, Simone C / Moreno, Andrea M

    Microorganisms

    2024  Volume 12, Issue 1

    Abstract: This study aimed to characterize ... ...

    Abstract This study aimed to characterize 300
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12010176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Medición de indicadores de calidad en medicina cardiovascular. Una necesidad inaplazable

    Darío Echeverri / Andrea L. Alarcón / Pedro R. Moreno

    Gaceta Médica de México, Vol 30, Iss

    2023  Volume 3

    Keywords Public aspects of medicine ; RA1-1270 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Permanyer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Noise analysis in direct detection and coherent detection phase-sensitive optical time-domain reflectometry systems.

    Vidal-Moreno, Pedro J / Becerril, Carlos / Fernández-Ruiz, María R / Martins, Hugo / Martin-Lopez, Sonia / Gonzalez-Herraez, Miguel

    Optics express

    2023  Volume 31, Issue 17, Page(s) 27450–27461

    Abstract: This study compares noise and signal-to-noise ratio (SNR) in direct detection and coherent detection fiber-based distributed acoustic sensing (DAS) systems. Both detection schemes employ the dynamic analysis of Rayleigh-backscattered light in phase- ... ...

    Abstract This study compares noise and signal-to-noise ratio (SNR) in direct detection and coherent detection fiber-based distributed acoustic sensing (DAS) systems. Both detection schemes employ the dynamic analysis of Rayleigh-backscattered light in phase-sensitive optical time-domain reflectometry (ΦOTDR) systems. Through theoretical and experimental analysis, it is determined that for photodetection filters with a sufficiently narrow bandwidth, the SNR performance of both detection schemes is comparable. However, for filters with poor selectivity, coherent detection was found to exhibit superior performance. These findings provide crucial guidelines for the design of high-performance time-domain DAS systems.
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.487978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strengthening the Achilles heel of high-risk plaques.

    Moreno, Pedro R

    Journal of the American College of Cardiology

    2014  Volume 64, Issue 21, Page(s) 2218–2221

    MeSH term(s) Atorvastatin Calcium ; Coronary Vessels/pathology ; Female ; Heptanoic Acids/administration & dosage ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Male ; Plaque, Atherosclerotic/pathology ; Pyrroles/administration & dosage ; Tomography, Optical Coherence
    Chemical Substances Heptanoic Acids ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Pyrroles ; Atorvastatin Calcium (48A5M73Z4Q)
    Language English
    Publishing date 2014-12-02
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2014.09.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Prediction of MACE after ACS: demographics and angiography versus imaging.

    Moreno, Pedro R

    JACC. Cardiovascular imaging

    2013  Volume 6, Issue 12, Page(s) 1273–1276

    MeSH term(s) Acute Coronary Syndrome/diagnostic imaging ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Vessels/diagnostic imaging ; Female ; Humans ; Male ; Plaque, Atherosclerotic
    Language English
    Publishing date 2013-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2491503-8
    ISSN 1876-7591 ; 1936-878X
    ISSN (online) 1876-7591
    ISSN 1936-878X
    DOI 10.1016/j.jcmg.2013.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Colon-available mango (poly)phenols exhibit mitigating effects on the intestinal barrier function in human intestinal cell monolayers under inflammatory conditions.

    Pereira-Caro, Gema / Cáceres-Jiménez, Salud / Moreno-Ortega, Alicia / Dobani, Sara / Pourshahidi, Kirsty / Gill, Chris I R / Mena, Pedro / Del Rio, Daniele / Moreno-Rojas, José Manuel / Taurino, Giuseppe / Bussolati, Ovidio / Almutairi, Tahani M / Crozier, Alan / Bianchi, Massimiliano G

    Food & function

    2024  

    Abstract: This study investigated the impact ... ...

    Abstract This study investigated the impact of
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d4fo00451e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Revascularization Strategies in Patients with Diabetes and Acute Coronary Syndromes.

    Scudeler, Thiago L / Godoy, Lucas C / Hoxha, Tedi / Kung, Andrew / Moreno, Pedro R / Farkouh, Michael E

    Current cardiology reports

    2022  Volume 24, Issue 3, Page(s) 201–208

    Abstract: Purpose of review: To review the current evidence for coronary revascularization in patients with diabetes mellitus (DM) in the setting of an acute coronary syndrome (ACS).: Recent findings: In patients with DM and stable multivessel ischemic heart ... ...

    Abstract Purpose of review: To review the current evidence for coronary revascularization in patients with diabetes mellitus (DM) in the setting of an acute coronary syndrome (ACS).
    Recent findings: In patients with DM and stable multivessel ischemic heart disease, coronary artery bypass graft surgery (CABG) has been observed to be superior to percutaneous coronary intervention (PCI) in long-term follow-up, leading to lower rates of all-cause mortality, myocardial infarction, and repeat revascularization. In the ACS setting, PCI remains the most frequently performed procedure. In patients with an ST-segment-elevation myocardial infarction (STEMI), primary PCI should be the revascularization method of choice, whenever feasible. Controversy still exists regarding when and how to deal with possible residual lesions. In the non-ST-segment-elevation (NSTE) ACS setting, although there are no data from randomized controlled trials (RCTs), recent observational data and sub-analyses of randomized studies have suggested that CABG may be the preferred approach for patients with DM and multivessel coronary disease. There is a paucity of RCTs evaluating revascularization strategies (PCI and CABG) in patients with DM and ACS. CABG may be a viable strategy, leading to improved outcomes, especially following NSTE-ACS.
    MeSH term(s) Acute Coronary Syndrome/surgery ; Coronary Artery Bypass/methods ; Coronary Artery Disease/surgery ; Diabetes Mellitus ; Humans ; Myocardial Infarction/surgery ; Percutaneous Coronary Intervention ; Treatment Outcome
    Language English
    Publishing date 2022-01-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2055373-0
    ISSN 1534-3170 ; 1523-3782
    ISSN (online) 1534-3170
    ISSN 1523-3782
    DOI 10.1007/s11886-022-01646-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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