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  1. Article ; Online: HFSA Government Affairs: Advocating for Our Members, Patients and Society.

    Teerlink, John R

    Journal of cardiac failure

    2023  Volume 29, Issue 9, Page(s) 1340–1341

    Language English
    Publishing date 2023-09-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4340: Show issues Location:
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  2. Article ; Online: Nurturing the Future of Heart Failure: The HFSA Advanced Heart Failure and Transplant Cardiology Task Force.

    Teerlink, John R

    Journal of cardiac failure

    2023  Volume 29, Issue 4, Page(s) 544–545

    MeSH term(s) Humans ; United States/epidemiology ; Heart Failure/diagnosis ; Heart Failure/surgery ; Heart Transplantation ; Cardiology ; Advisory Committees ; American Heart Association
    Language English
    Publishing date 2023-04-14
    Publishing country United States
    Document type Editorial
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: HFSA: Serving Those Who Serve Heart Failure Patients.

    Teerlink, John R

    Journal of cardiac failure

    2022  Volume 28, Issue 12, Page(s) 1745

    MeSH term(s) Humans ; United States ; Heart Failure/diagnosis ; Heart Failure/therapy ; Heart Transplantation ; American Heart Association
    Language English
    Publishing date 2022-12-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2022.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pathophysiology and Therapeutic Approaches to Acute Decompensated Heart Failure.

    Njoroge, Joyce N / Teerlink, John R

    Circulation research

    2021  Volume 128, Issue 10, Page(s) 1468–1486

    Abstract: Acute decompensated heart failure (ADHF) is one of the leading admission diagnoses worldwide, yet it is an entity with incompletely understood pathophysiology and limited therapeutic options. Patients admitted for ADHF have high in-hospital morbidity and ...

    Abstract Acute decompensated heart failure (ADHF) is one of the leading admission diagnoses worldwide, yet it is an entity with incompletely understood pathophysiology and limited therapeutic options. Patients admitted for ADHF have high in-hospital morbidity and mortality, as well as frequent rehospitalizations and subsequent cardiovascular death. This devastating clinical course is partly due to suboptimal medical management of ADHF with persistent congestion upon hospital discharge and inadequate predischarge initiation of life-saving guideline-directed therapies. While new drugs for the treatment of chronic HF continue to be approved, there has been no new therapy approved for ADHF in decades. This review will focus on the current limited understanding of ADHF pathophysiology, possible therapeutic targets, and current limitations in expanding available therapies in light of the unmet need among these high-risk patients.
    MeSH term(s) Acute Disease ; Body Fluids/physiology ; Cardio-Renal Syndrome/complications ; Cardiotoxins/therapeutic use ; Comorbidity ; Heart Failure/diagnosis ; Heart Failure/drug therapy ; Heart Failure/etiology ; Heart Failure/physiopathology ; Hospitalization ; Humans ; Inflammation Mediators/metabolism ; Myocardial Contraction/physiology ; Natriuretic Peptide, Brain/metabolism ; Patient Discharge ; Patient Readmission ; Renin-Angiotensin System/physiology ; Symptom Assessment ; Vascular Resistance ; Vasoconstriction/physiology ; Vasodilator Agents/therapeutic use
    Chemical Substances Cardiotoxins ; Inflammation Mediators ; Vasodilator Agents ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.121.318186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui IV Zs.70: Show issues Location:
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  5. Article ; Online: Systolic time intervals in patients with heart failure: time to teach new dogs old tricks.

    Njoroge, Joyce N / Teerlink, John R

    European journal of heart failure

    2020  Volume 22, Issue 7, Page(s) 1183–1185

    MeSH term(s) Animals ; Dogs ; Heart Failure/epidemiology ; Humans ; Stroke Volume ; Systole
    Language English
    Publishing date 2020-02-13
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.1725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5299: Show issues Location:
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  6. Article ; Online: Assessing the lifetime benefit of heart failure therapies.

    Psotka, Mitchell A / Teerlink, John R

    Lancet (London, England)

    2020  Volume 396, Issue 10244, Page(s) 75–77

    MeSH term(s) Clinical Decision-Making/ethics ; Clinical Trials as Topic ; Cost-Benefit Analysis/statistics & numerical data ; Female ; Heart Failure/drug therapy ; Heart Failure/mortality ; Heart Failure/physiopathology ; Humans ; Male ; Patient Care Team/organization & administration ; Stroke Volume/drug effects
    Language English
    Publishing date 2020-05-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)30929-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Omecamtiv Mecarbil in Systolic Heart Failure. Reply.

    Teerlink, John R / Felker, G Michael / McMurray, John J V

    The New England journal of medicine

    2021  Volume 384, Issue 20, Page(s) 1967–1968

    MeSH term(s) Heart Failure, Systolic/drug therapy ; Humans ; Stroke Volume ; Urea/analogs & derivatives
    Chemical Substances omecamtiv mecarbil (2M19539ERK) ; Urea (8W8T17847W)
    Language English
    Publishing date 2021-05-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2102893
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    Ua VI Zs.34: Show issues Location:
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  8. Article ; Online: Inotropic therapies in heart failure and cardiogenic shock: an educational review.

    DesJardin, Jacqueline T / Teerlink, John R

    European heart journal. Acute cardiovascular care

    2021  Volume 10, Issue 6, Page(s) 676–686

    Abstract: Reduced systolic function is central to the pathophysiology and clinical sequelae of acute decompensated heart failure (ADHF) with reduced ejection fraction and cardiogenic shock. These clinical entities are the final common pathway for marked ... ...

    Abstract Reduced systolic function is central to the pathophysiology and clinical sequelae of acute decompensated heart failure (ADHF) with reduced ejection fraction and cardiogenic shock. These clinical entities are the final common pathway for marked deterioration of right or left ventricular function and can occur in multiple clinical presentations including severe ADHF, myocardial infarction, post-cardiac surgery, severe pulmonary hypertension, and advanced or end-stage chronic heart failure. Inotropic therapies improve ventricular systolic function and may be divided into three classes on the basis of their mechanism of action (calcitropes, mitotropes, and myotropes). Most currently available therapies for cardiogenic shock are calcitropes which can provide critical haemodynamic support, but also may increase myocardial oxygen demand, ischaemia, arrhythmia, and mortality. Emerging therapies to improve cardiac function such as mitotropes (e.g. perhexiline, SGLT2i) or myotropes (e.g. omecamtiv mecarbil) may provide useful alternatives in the future.
    MeSH term(s) Heart Failure/complications ; Heart Failure/drug therapy ; Humans ; Shock, Cardiogenic/drug therapy ; Shock, Cardiogenic/etiology ; Systole ; Ventricular Dysfunction, Left ; Ventricular Function, Left
    Language English
    Publishing date 2021-07-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuab047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Empower the Future… Even Oprah Had a Mentor!

    Psotka, Mitchell A / O'Connor, Christopher M / Teerlink, John R

    JACC. Heart failure

    2021  Volume 9, Issue 8, Page(s) 604–605

    MeSH term(s) Heart Failure ; Humans ; Mentors
    Language English
    Publishing date 2021-07-29
    Publishing country United States
    Document type Editorial
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2021.06.006
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  10. Article ; Online: Patient-Reported Outcome Instruments in Heart Failure: Are They Preserved?

    Psotka, Mitchell A / Teerlink, John R

    JACC. Heart failure

    2018  Volume 6, Issue 7, Page(s) 561–563

    MeSH term(s) Heart Failure ; Humans ; Mineralocorticoid Receptor Antagonists ; Patient Reported Outcome Measures ; Quality of Life ; Stroke Volume
    Chemical Substances Mineralocorticoid Receptor Antagonists
    Language English
    Publishing date 2018-06-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2018.03.008
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