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  1. Article ; Online: Is there a temporal relationship between atrial fibrillation and stroke? A review.

    Dlima, Jessica / Kitisarn, Rooj / Lim, Han / Thijs, Vincent

    BMJ neurology open

    2024  Volume 6, Issue 1, Page(s) e000512

    Abstract: Importance: Atrial fibrillation (AF) is an established risk factor for ischaemic stroke. The introduction of continuous cardiac rhythm monitoring devices has enabled detection of brief and asymptomatic episodes of AF.: Observations: The search ... ...

    Abstract Importance: Atrial fibrillation (AF) is an established risk factor for ischaemic stroke. The introduction of continuous cardiac rhythm monitoring devices has enabled detection of brief and asymptomatic episodes of AF.
    Observations: The search yielded 727 studies, 11 of which met the inclusion criteria. Four studies suggested a strong temporal association between episodes of AF and stroke, while seven indicated a weak relationship. The conflicting nature of the studies may be attributed to inconsistencies in ischaemic stroke verification (n=5/11), event rate and power (n=6/11) and lack of controlling for anticoagulation (n=10/11), mitigating the relationship between AF episodes and stroke.
    Conclusions and relevance: The temporal relationship between AF and stroke still remains unclear due to varying study methodology, lack of control for anticoagulation and inconsistent stroke subtyping. Our review identifies limitations to the current literature and makes recommendations for future studies assessing the temporal relationship between AF episodes and cardioembolic stroke.
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ISSN 2632-6140
    ISSN (online) 2632-6140
    DOI 10.1136/bmjno-2023-000512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Radiomics Studies on Ischemic Stroke and Carotid Atherosclerotic Disease: A Reporting Quality Assessment.

    Beaudoin, Ann-Marie / Ho, Jan Kee / Lam, Adrienne / Thijs, Vincent

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2024  , Page(s) 8465371241234545

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/08465371241234545
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    Zs.A 299: Show issues Location:
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  3. Article ; Online: Coronary atherosclerosis in athletes: recent insights and clinical considerations.

    Aengevaeren, Vincent L / Claessen, Guido / Eijsvogels, Thijs Mh

    British journal of sports medicine

    2024  

    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Editorial
    ZDB-ID 600592-5
    ISSN 1473-0480 ; 0306-3674
    ISSN (online) 1473-0480
    ISSN 0306-3674
    DOI 10.1136/bjsports-2023-107938
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  4. Article ; Online: Atrial Fibrillation Detection: Fishing for An Irregular Heartbeat Before and After Stroke.

    Thijs, Vincent

    Stroke

    2017  Volume 48, Issue 10, Page(s) 2671–2677

    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.117.017083
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  5. Article ; Online: Correction to: Exercise-induced myocardial damage is associated with cardiac edema and dysfunction: adding another piece to the troponin puzzle.

    Eijsvogels, Thijs M H / Aengevaeren, Vincent L

    European journal of applied physiology

    2023  Volume 123, Issue 11, Page(s) 2585

    Language English
    Publishing date 2023-09-06
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-023-05301-5
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  6. Article ; Online: Exercise-induced myocardial damage is associated with cardiac edema and dysfunction: adding another piece to the troponin puzzle.

    Eijsvogels, Thijs M H / Aengevaeren, Vincent L

    European journal of applied physiology

    2023  Volume 123, Issue 10, Page(s) 2103–2105

    MeSH term(s) Humans ; Troponin ; Edema, Cardiac ; Myocardium ; Biomarkers ; Troponin T
    Chemical Substances Troponin ; Biomarkers ; Troponin T
    Language English
    Publishing date 2023-07-26
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-023-05282-5
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  7. Article ; Online: Temporal Association Between Atrial Fibrillation and Ischemic Stroke: Systematic Review and Meta-Analysis.

    D'lima, Jessica / Thijs, Vincent / Lim, Han / Rodrigues, Thalys Sampaio / Beaudoin, Ann-Marie

    International journal of stroke : official journal of the International Stroke Society

    2024  , Page(s) 17474930241253482

    Abstract: Background: Paroxysmal atrial fibrillation (PAF) is strongly associated with ischemic stroke. Continuous cardiac implantable electronic devices (CIEDs) can assess PAF episodes over prolonged periods. Studies that attempted to find a temporal association ...

    Abstract Background: Paroxysmal atrial fibrillation (PAF) is strongly associated with ischemic stroke. Continuous cardiac implantable electronic devices (CIEDs) can assess PAF episodes over prolonged periods. Studies that attempted to find a temporal association between PAF and ischemic stroke were inconclusive. Thus, we performed a systematic review and meta-analysis to assess this relationship.
    Aims: To assess the temporal association between AF episodes and stroke within 30 days of the arrhythmic episode. The secondary outcome is a temporal association within a 90-day period.
    Summary of review: A total of 2804 studies that discussed the temporal relationship between PAF and ischemic stroke were screened, and 7 studies were included in the meta-analysis. Amongst the 4041 patients included in these studies, there were 138 patients with device detected PAF episodes and stroke. Four studies used a 30-day window for temporality and the pooled OR showed a significant association (OR 4.11 [95% CI 1.03-16.40]). The 3 studies reporting on AF and stroke within a 90 day window did not find a significant temporal relationship (OR of 0.43 [95% CI 0.13-1.41]). Finally, the pooled result of those 7 studies did not show a significant association (OR 1.51 [95% CI 0.44 - 5.17]).
    Conclusions: This meta-analysis supports a temporal relationship between PAF and ischemic stroke within a 30-day window. Establishing this relationship is important for individualized risk prediction and targeted anticoagulation treatment.
    Language English
    Publishing date 2024-04-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2303728-3
    ISSN 1747-4949 ; 1747-4930
    ISSN (online) 1747-4949
    ISSN 1747-4930
    DOI 10.1177/17474930241253482
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  8. Article ; Online: White Matter Disease Progression and Incident Stroke: A Very Long-Term Perspective.

    Gardener, Hannah / Thijs, Vincent

    Stroke

    2020  Volume 51, Issue 11, Page(s) 3197–3199

    MeSH term(s) Brain ; Disease Progression ; Humans ; Leukoencephalopathies ; Stroke/epidemiology ; White Matter/diagnostic imaging
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.032148
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    Zs.A 448: Show issues Location:
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  9. Article ; Online: High frequency of anticoagulation management errors preceding ischaemic strokes in atrial fibrillation.

    Wong, Edmond / Aaqib, Muhammad / Thijs, Vincent

    Internal medicine journal

    2022  Volume 52, Issue 6, Page(s) 1024–1028

    Abstract: Background: Anticoagulants are recommended to prevent cardioembolic stroke in most patients with atrial fibrillation (AF). Management errors with anticoagulation and use of aspirin instead of anticoagulants have been documented worldwide, especially ... ...

    Abstract Background: Anticoagulants are recommended to prevent cardioembolic stroke in most patients with atrial fibrillation (AF). Management errors with anticoagulation and use of aspirin instead of anticoagulants have been documented worldwide, especially with vitamin K antagonists.
    Aims: To assess the rate of anticoagulant mismanagement errors in patients admitted with ischaemic stroke and the clinical correlates with stroke outcomes in the era of non-vitamin K oral anticoagulants.
    Methods: We performed a retrospective analysis of patients admitted with ischaemic stroke and history of AF to a single-centre tertiary hospital stroke unit in Melbourne, Australia, between January 2016 and June 2019. We assessed management errors as defined using European Heart Rhythm Association criteria with anticoagulation in the 2 weeks prior to the index stroke.
    Results: A total of 306 patients with AF and ischaemic stroke was included, of whom 196 (64%) had management errors. Patients with management errors were older (median age 84 vs 81 years; P = 0.002) and more often female (53% vs 38%; P = 0.02). Of those with management errors, 74 (37%) were not prescribed any anticoagulation despite increased stroke risk and absence of contraindications and 40 (20%) had anticoagulation inappropriately ceased. Mortality at 3 months was 32% in those with management errors, compared with 17% in the appropriately anticoagulated group (P = 0.005).
    Conclusions: Inappropriate management of anticoagulants is present in the majority of acute ischaemic stroke in the 2 weeks preceding the event and is linked to higher mortality. Improved anticoagulation practice has the potential to substantially reduce stroke rates in patients with AF.
    MeSH term(s) Administration, Oral ; Aged, 80 and over ; Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/epidemiology ; Brain Ischemia/epidemiology ; Brain Ischemia/prevention & control ; Female ; Humans ; Ischemic Stroke ; Retrospective Studies ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-05-31
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15167
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  10. Article ; Online: Exercise at the Extremes: Unraveling the Mechanisms of Deleterious Cardiovascular Adaptations.

    Eijsvogels, Thijs M H / Aengevaeren, Vincent L

    JACC. Basic to translational science

    2022  Volume 7, Issue 7, Page(s) 694–696

    Language English
    Publishing date 2022-07-25
    Publishing country United States
    Document type Editorial
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2022.04.012
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