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  1. Article ; Online: Atypical mucosal lesions may help in the early diagnosis of monkeypox

    Yijia He / Bin Wang / Linxi Zeng / Guoqiang Zhang

    European Journal of Inflammation, Vol

    2023  Volume 21

    Abstract: Since May 2022, monkeypox has been gradually spreading across countries. In past reports and treatment consensus, monkeypox is most widely known for its characteristic skin lesions, which are hard, spherical rashes that appear as herpes and pustules and ... ...

    Abstract Since May 2022, monkeypox has been gradually spreading across countries. In past reports and treatment consensus, monkeypox is most widely known for its characteristic skin lesions, which are hard, spherical rashes that appear as herpes and pustules and are widely distributed centrifugally over all parts of the body. Prior to the appearance of the rash, carriers of monkeypox are likely to spread the virus to more susceptible people. Attention to the early atypical mucosal manifestations of monkeypox allows for early identification of potential cases of monkeypox, thereby controlling the further spread of the epidemic.
    Keywords Medicine ; R
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Corrigendum to "Antihypertensive effect of soybean bioactive peptides: A review" [Curr Opin Pharmacol (62) (2022) 74-81].

    Li, Tingna / Zhang, Xiaorui / Ren, Yuanyuan / Zeng, Yijia / Huang, Qinwan / Wang, Chao

    Current opinion in pharmacology

    2023  Volume 71, Page(s) 102383

    Language English
    Publishing date 2023-06-03
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2037057-X
    ISSN 1471-4973 ; 1471-4892
    ISSN (online) 1471-4973
    ISSN 1471-4892
    DOI 10.1016/j.coph.2023.102383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5608: Show issues Location:
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  3. Article: An Imbalance in Histone Modifiers Induces tRNA-Cys-GCA Overexpression and tRF-27 Accumulation by Attenuating Promoter H3K27me3 in Primary Trastuzumab-Resistant Breast Cancer.

    Duan, Ningjun / Hua, Yijia / Yan, Xueqi / He, Yaozhou / Zeng, Tianyu / Gong, Jue / Fu, Ziyi / Li, Wei / Yin, Yongmei

    Cancers

    2024  Volume 16, Issue 6

    Abstract: tRNA-derived fragments (tRFs) play crucial roles in cancer progression. Among them, tRF-27 has been identified as a key factor in ... ...

    Abstract tRNA-derived fragments (tRFs) play crucial roles in cancer progression. Among them, tRF-27 has been identified as a key factor in promoting
    Language English
    Publishing date 2024-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16061118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Azomycin Orchestrate Colistin-Resistant

    Hu, Panjie / Chen, Huanchang / Zhao, Deyi / Ma, Zhexiao / Zeng, Weiliang / Han, Yijia / Zhou, Tieli / Cao, Jianming / Shen, Mo

    ACS infectious diseases

    2024  Volume 10, Issue 2, Page(s) 662–675

    Abstract: ... ...

    Abstract The
    MeSH term(s) Animals ; Mice ; Colistin/pharmacology ; Enterobacter cloacae ; Anti-Bacterial Agents/pharmacology ; Nitroimidazoles
    Chemical Substances Colistin (Z67X93HJG1) ; azomycin (K8E96XL55D) ; Anti-Bacterial Agents ; Nitroimidazoles
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ISSN 2373-8227
    ISSN (online) 2373-8227
    DOI 10.1021/acsinfecdis.3c00526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Unveiling Alterations of Epigenetic Modifications and Chromatin Architecture Leading to Lipid Metabolic Reprogramming during the Evolutionary Trastuzumab Adaptation of HER2-Positive Breast Cancer.

    Duan, Ningjun / Hua, Yijia / Yan, Xueqi / He, Yaozhou / Zeng, Tianyu / Gong, Jue / Fu, Ziyi / Li, Wei / Yin, Yongmei

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  , Page(s) e2309424

    Abstract: Secondary trastuzumab resistance represents an evolutionary adaptation of HER2-positive breast cancer during anti-HER2 treatment. Most current studies have tended to prioritize HER2 and its associated signaling pathways, often overlooking broader but ... ...

    Abstract Secondary trastuzumab resistance represents an evolutionary adaptation of HER2-positive breast cancer during anti-HER2 treatment. Most current studies have tended to prioritize HER2 and its associated signaling pathways, often overlooking broader but seemingly less relevant cellular processes, along with their associated genetic and epigenetic mechanisms. Here, transcriptome data is not only characterized but also examined epigenomic and 3D genome architecture information in both trastuzumab-sensitive and secondary-resistant breast cancer cells. The findings reveal that the global metabolic reprogramming associated with trastuzumab resistance may stem from genome-wide alterations in both histone modifications and chromatin structure. Specifically, the transcriptional activities of key genes involved in lipid metabolism appear to be regulated by variant promoter H3K27me3 and H3K4me3 modifications, as well as promoter-enhancer interactions. These discoveries offer valuable insights into how cancer cells adapt to anti-tumor drugs and have the potential to impact future diagnostic and treatment strategies.
    Language English
    Publishing date 2024-03-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202309424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Plasma-Engraved Lattice-Matched NiO/NiFe2O4 Heterostructure with Ample Oxygen Vacancies for Efficient Water Electrolysis and Zn-Air Batteries.

    Zeng, Kai / Tao, Hongwei / Zhaoshi, Yijia / Feng, Jiawen / Jiang, Shuhao / Wu, Yanfang / Yang, Ruizhi / He, Zhengyou / Li, Yibing

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e202401272

    Abstract: Heterogeneous interface and defect engineering offer effective pathways to accelerate oxygen evolution reaction (OER) charge transfer kinetics and motivate optimal intrinsic catalytic activity. Herein, we report the lattice-matched NiO/NiFe2O4 ... ...

    Abstract Heterogeneous interface and defect engineering offer effective pathways to accelerate oxygen evolution reaction (OER) charge transfer kinetics and motivate optimal intrinsic catalytic activity. Herein, we report the lattice-matched NiO/NiFe2O4 heterostructure with ample oxygen vacancies (Vo-NiO/NiFe2O4) induced by a feasible hydrothermal followed by calcination and plasma-engraving assistant technique, which shows the unique porous microflower arrangement of intertwined nanosheets. Benefitting from the synergetic effects between lattice-matched heterointerface and oxygen vacancies induce the strong electronic coupling, optimized OH-/O2 diffusion pathway and ample active sites, thus-prepared Vo-NiFe2O4 presents a favorable OER performance with a low overpotential (261 mV @ 10 mA cm-2) and small Tafel slope (39.4 mV dec-1), even surpassing commercial RuO2 catalyst. Additionally, the two-electrode configuration water electrolyzer and rechargeable zinc-air battery assembled by Vo-NiO/NiFe2O4 catalyst show the potential practical application directions. This work provides an innovative avenue for strengthening OER performance toward water electrolysis and Zn-air batteries via the interface and vacancy engineering strategy.
    Language English
    Publishing date 2024-04-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202401272
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  7. Article ; Online: Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders.

    Xia, Yijia / Wang, Tianbao / Ma, Zhipeng / Ying, Rongtao / Shao, Shiliang / Zeng, Jurong / Zhang, Chuantao

    Journal of visualized experiments : JoVE

    2023  , Issue 198

    Abstract: Chronic obstructive pulmonary disease (COPD) is a clinical syndrome characterized by persistent and irreversible airflow limitation and chronic respiratory symptoms. It has a wide spectrum of complications, and sleep disorders, as part of it, are common ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) is a clinical syndrome characterized by persistent and irreversible airflow limitation and chronic respiratory symptoms. It has a wide spectrum of complications, and sleep disorders, as part of it, are common in severe cases, especially in elderly patients. Long-term lack of sleep may lead to the aggravation of the original disease, reducing patients' quality of life. Benzodiazepines are mainly used for symptomatic treatment of COPD combined with sleep disorders. However, such drugs have the side effect of respiratory central inhibition and could probably aggravate hypoxia symptoms. Auricular acupuncture is a special method of treating physical and psychosomatic dysfunctions by stimulating specific points in the ear. This article explains the specific methods of clinical operation of auricular acupuncture in detail, including assessment of patient eligibility, medical devices used, acupuncture points, course of treatment, post-treatment care, responses to emergencies, etc. The Pittsburgh sleep quality index (PSQI) and chronic obstructive pulmonary disease assessment scale (CAT) were used as the observational index of this method. So far, clinical reports have proved that auricular acupuncture has a definite curative effect in the treatment of COPD combined with sleep disorders, and its advantages of simple operation, few adverse reactions are worthy of further study and promotion, which provide a reference for the clinical treatment of such diseases.
    MeSH term(s) Humans ; Acupuncture, Ear ; Medicine, Chinese Traditional ; Quality of Life ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/therapy ; Sleep Wake Disorders/etiology ; Sleep Wake Disorders/therapy
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article ; Video-Audio Media ; Research Support, Non-U.S. Gov't
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/65297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An UPLC-MS/MS method for targeted analysis of microbial and host tryptophan metabolism after administration of polysaccharides from Atractylodes macrocephala Koidz. in ulcerative colitis mice.

    Hu, Pan / Yan, Xin / Zeng, Yijia / Jiang, Zherui / Liu, Juan / Feng, Wu-Wen

    Journal of pharmaceutical and biomedical analysis

    2023  Volume 235, Page(s) 115585

    Abstract: Botanic polysaccharides can be metabolized by gut microbiota into short-chain fatty acids (SCFAs) to exert extensive bioactivities, yet targeted analysis of the effect of botanic polysaccharides on other gut microbial metabolites is scarcely seen. ... ...

    Abstract Botanic polysaccharides can be metabolized by gut microbiota into short-chain fatty acids (SCFAs) to exert extensive bioactivities, yet targeted analysis of the effect of botanic polysaccharides on other gut microbial metabolites is scarcely seen. Tryptophan metabolites such as indole and indole derivatives play import roles in health and disease development. Using polysaccharides from Atractylodes macrocephala Koidz. (AMP) in treating ulcerative colitis as the example, we checked the effects of AMP on tryptophan metabolites. After examination of pharmacological effects of AMP, we established an ultra-performance liquid chromatography coupled with mass spectrometry/mass spectrometry (UPLC-MS/MS) method to simultaneously determinate the levels of 30 tryptophan metabolites and used the method to determine the levels of these metabolites in feces and plasma. The detection results showed that 12 metabolites in feces can be detected, and 17 metabolites can be detected in plasma samples. In addition, we found out that total levels of aryl hydrocarbon receptor ligands were decreased in colitis model whereas AMP treatment can increase the levels of total ligands in both feces and plasma. The results indicated that the therapeutical effect of AMP on colitis was associated with modulation of fecal and host tryptophan metabolism. This study provides new insight into the molecular mechanisms of polysaccharides that the beneficial effects of polysaccharides can be achieved by modulating microbial tryptophan metabolism in addition to SCFAs.
    MeSH term(s) Animals ; Mice ; Colitis, Ulcerative/drug therapy ; Atractylodes/chemistry ; Tryptophan/metabolism ; Chromatography, High Pressure Liquid ; Chromatography, Liquid ; Ligands ; Tandem Mass Spectrometry ; Colitis ; Polysaccharides/chemistry
    Chemical Substances Tryptophan (8DUH1N11BX) ; Ligands ; Polysaccharides
    Language English
    Publishing date 2023-07-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 604917-5
    ISSN 1873-264X ; 0731-7085
    ISSN (online) 1873-264X
    ISSN 0731-7085
    DOI 10.1016/j.jpba.2023.115585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1850: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article: The Micro Hand S vs. da Vinci Surgical Robot-Assisted Surgery on Total Mesorectal Excision: Short-Term Outcomes Using Propensity Score Matching Analysis.

    Zeng, Yijia / Wang, Guohui / Li, Zheng / Lin, Hao / Zhu, Shaihong / Yi, Bo

    Frontiers in surgery

    2021  Volume 8, Page(s) 656270

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2021-05-11
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2021.656270
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  10. Article ; Online: Sleeve gastrectomy decreased hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.

    Zeng, Runzhi / Zeng, Yijia / Wang, Qi / Li, Xinzhang / Liu, Jize / Li, Bingjun / Zhang, Guangyong / Hu, Sanyuan

    Biochemical and biophysical research communications

    2023  Volume 653, Page(s) 115–125

    Abstract: This study was designed to investigate the roles of autophagy in the attenuation of hepatic lipid accumulation after sleeve gastrectomy (SG). Thirty-two rats were divided into normal control, obesity group, sham group, and SG group. Then serum glucagon- ... ...

    Abstract This study was designed to investigate the roles of autophagy in the attenuation of hepatic lipid accumulation after sleeve gastrectomy (SG). Thirty-two rats were divided into normal control, obesity group, sham group, and SG group. Then serum glucagon-like polypeptide-1 (GLP-1) and lipid accumulation were determined, followed by measuring the activity of autophagy based on immunohistochemistry (IHC) and Western blot analysis. Our data showed significant decrease in the lipid accumulation after SG compared with sham group. GLP-1 and autophagy showed significant increase in rats underwent SG compared with the sham group (P < 0.05). In vitro experiments were conducted to analyze the roles of GLP-1 in autophagy. We knock-downed the expression of Beclin-1 in HepG2, and then analyzed the expression of autophagy-related protein (i.e. LC3BII and LC3BI) and lipid droplet accumulation. In HepG2 cells, GLP-1 analog reduced lipid accumulation by activating autophagy through modulating the AMPK/mTOR signaling pathway. All these concluded that SG decreased hepatic lipid accumulation by inducing autophagy through modulating AMPK/mTOR pathway.
    MeSH term(s) Animals ; Rats ; AMP-Activated Protein Kinases/metabolism ; Autophagy ; Gastrectomy ; Glucagon-Like Peptide 1/metabolism ; Lipids ; TOR Serine-Threonine Kinases/metabolism
    Chemical Substances AMP-Activated Protein Kinases (EC 2.7.11.31) ; Glucagon-Like Peptide 1 (89750-14-1) ; Lipids ; mTOR protein, rat (EC 2.7.1.1) ; TOR Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2023-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.02.071
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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