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  1. Article: Anhörung zum Referentenentwurf. Terminservice- und Versorgungsgesetz

    Urban, Roland

    Neurotransmitter

    2018  Volume 29, Issue 10, Page(s) 6

    Language German
    Document type Article
    ZDB-ID 1362825-2
    ISSN 1436-123X
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5037: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Woher kommt die Gewalt?

    Urban, Roland

    Neurotransmitter

    2016  Volume 27, Issue 1, Page(s) 19

    Language German
    Document type Article
    ZDB-ID 1362825-2
    ISSN 1436-123X
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5037: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: In Situ Performance Monitoring of Electrochemical Oxygen and Hydrogen Peroxide Sensors in an Additively Manufactured Modular Microreactor.

    Doering, Moritz / Trinkies, Laura L / Kieninger, Jochen / Kraut, Manfred / Rupitsch, Stefan J / Dittmeyer, Roland / Urban, Gerald A / Weltin, Andreas

    ACS omega

    2024  Volume 9, Issue 17, Page(s) 19700–19711

    Abstract: Miniaturized and microstructured reactors in process engineering are essential for a more decentralized, flexible, sustainable, and resilient chemical production. Modern, additive manufacturing methods for metals enable complex reactor-geometries, ... ...

    Abstract Miniaturized and microstructured reactors in process engineering are essential for a more decentralized, flexible, sustainable, and resilient chemical production. Modern, additive manufacturing methods for metals enable complex reactor-geometries, increased functionality, and faster design iterations, a clear advantage over classical subtractive machining and polymer-based approaches. Integrated microsensors allow online, in situ process monitoring to optimize processes like the direct synthesis of hydrogen peroxide. We developed a modular tube-in-tube membrane reactor fabricated from stainless steel via 3D printing by laser powder bed fusion of metals (PBF-LB/M). The reactor concept enables the spatially separated dosage and resaturation of two gaseous reactants across a membrane into a liquid process medium. Uniquely, we integrated platinum-based electrochemical sensors for the online detection of analytes to reveal the dynamics inside the reactor. An advanced chronoamperometric protocol combined the simultaneous concentration measurement of hydrogen peroxide and oxygen with monitoring of the sensor performance and self-calibration in long-term use. We demonstrated the highly linear and sensitive monitoring of hydrogen peroxide and dissolved oxygen entering the liquid phase through the membrane. Our measurements delivered important real-time insights into the dynamics of the concentrations in the reactor, highlighting the power of electrochemical sensors applied in process engineering. We demonstrated the stable continuous measurement over 1 week and estimated the sensor lifetime for months in the acidic process medium. Our approach combines electrochemical sensors for process monitoring with advanced, additively manufactured stainless steel membrane microreactors, supporting the power of sensor-equipped microreactors as contributors to the paradigm change in process engineering and toward a greener chemistry.
    Language English
    Publishing date 2024-04-16
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.4c02210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Ländervertreterversammlung des BVDN

    Urban, Roland

    Neurotransmitter

    2015  Volume 26, Issue 6, Page(s) 12

    Language German
    Document type Article
    ZDB-ID 1362825-2
    ISSN 1436-123X
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5037: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Wechsel an der BVDN-Spitze und Neues aus der Telemedizin. Landesdelegiertenkonferenz 2016

    Urban, Roland

    Neurotransmitter

    2016  Volume 27, Issue 12, Page(s) 17

    Language German
    Document type Article
    ZDB-ID 1362825-2
    ISSN 1436-123X
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5037: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Zugänge schaffen: Möglichkeiten niedrigschwelliger Drogenarbeit in der Adoleszenz

    Urban, Roland

    Pädiatrie & Pädologie

    2015  Volume 50, Issue 5, Page(s) 212

    Language German
    Document type Article
    ZDB-ID 123417-1
    ISSN 0030-9338
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 526: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Zugänge schaffen

    Urban, Roland

    psychopraxis. neuropraxis

    Möglichkeiten niedrigschwelliger Drogenarbeit in der Adoleszenz

    2016  Volume 19, Issue 3, Page(s) 82–87

    Abstract: Berichtet wird über die Praxis der niedrigschwelligen Suchthilfe gegeben, die sich mit ihren Leistungen vorrangig an opiatabhängige oder polytoxikoman substanzabhängige Menschen richtet. Das Angebot ist auf den Sozialraum bezogen, szenenah und ... ...

    Title translation Possibilities of low threshold drug work with adolescents
    Abstract Berichtet wird über die Praxis der niedrigschwelligen Suchthilfe gegeben, die sich mit ihren Leistungen vorrangig an opiatabhängige oder polytoxikoman substanzabhängige Menschen richtet. Das Angebot ist auf den Sozialraum bezogen, szenenah und akzeptanzorientiert. Die Erfahrungen dieses Praxisberichts stammen aus der langjährigen Tätigkeit von "Kontaktladen und Streetwork im Drogenbereich", einer Einrichtung der Caritas Steiermark in Graz. Dieser Überblick dokumentiert die Möglichkeiten niedrigschwelliger Drogenarbeit, von denen auch junge Menschen während der Adoleszenz profitieren, und ergänzt diese mit Daten aus dem Jahresbericht des Kontaktladens von 2013.
    Keywords Addiction ; Adolescent Development ; Entwicklung im Jugendalter ; Niedrigschwellige Angebote ; Outreach Programs ; Social Casework ; Sozialarbeit ; Sucht
    Language German
    Document type Article
    ZDB-ID 1490519-x
    ISSN 1613-7590 ; 1434-1883
    ISSN (online) 1613-7590
    ISSN 1434-1883
    Database PSYNDEX

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5216: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: "That's just Future Medicine" - a qualitative study on users' experiences of symptom checker apps.

    Müller, Regina / Klemmt, Malte / Koch, Roland / Ehni, Hans-Jörg / Henking, Tanja / Langmann, Elisabeth / Wiesing, Urban / Ranisch, Robert

    BMC medical ethics

    2024  Volume 25, Issue 1, Page(s) 17

    Abstract: Background: Symptom checker apps (SCAs) are mobile or online applications for lay people that usually have two main functions: symptom analysis and recommendations. SCAs ask users questions about their symptoms via a chatbot, give a list with possible ... ...

    Abstract Background: Symptom checker apps (SCAs) are mobile or online applications for lay people that usually have two main functions: symptom analysis and recommendations. SCAs ask users questions about their symptoms via a chatbot, give a list with possible causes, and provide a recommendation, such as seeing a physician. However, it is unclear whether the actual performance of a SCA corresponds to the users' experiences. This qualitative study investigates the subjective perspectives of SCA users to close the empirical gap identified in the literature and answers the following main research question: How do individuals (healthy users and patients) experience the usage of SCA, including their attitudes, expectations, motivations, and concerns regarding their SCA use?
    Methods: A qualitative interview study was chosen to clarify the relatively unknown experience of SCA use. Semi-structured qualitative interviews with SCA users were carried out by two researchers in tandem via video call. Qualitative content analysis was selected as methodology for the data analysis.
    Results: Fifteen interviews with SCA users were conducted and seven main categories identified: (1) Attitudes towards findings and recommendations, (2) Communication, (3) Contact with physicians, (4) Expectations (prior to use), (5) Motivations, (6) Risks, and (7) SCA-use for others.
    Conclusions: The aspects identified in the analysis emphasise the specific perspective of SCA users and, at the same time, the immense scope of different experiences. Moreover, the study reveals ethical issues, such as relational aspects, that are often overlooked in debates on mHealth. Both empirical and ethical research is more needed, as the awareness of the subjective experience of those affected is an essential component in the responsible development and implementation of health apps such as SCA.
    Trial registration: German Clinical Trials Register (DRKS): DRKS00022465. 07/08/2020.
    MeSH term(s) Humans ; Mobile Applications ; Telemedicine ; Qualitative Research ; Communication ; Physicians
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041552-7
    ISSN 1472-6939 ; 1472-6939
    ISSN (online) 1472-6939
    ISSN 1472-6939
    DOI 10.1186/s12910-024-01011-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Lysine Methyltransferase 9 (KMT9) Is an Actionable Target in Muscle-Invasive Bladder Cancer.

    Totonji, Sainab / Ramos-Triguero, Anna / Willmann, Dominica / Sum, Manuela / Urban, Sylvia / Bauer, Helena / Rieder, Astrid / Wang, Sheng / Greschik, Holger / Metzger, Eric / Schüle, Roland

    Cancers

    2024  Volume 16, Issue 8

    Abstract: Novel treatment modalities are imperative for the challenging management of muscle-invasive and metastatic BC to improve patient survival rates. The recently identified KMT9, an obligate heterodimer composed of KMT9α and KMT9β, regulates the growth of ... ...

    Abstract Novel treatment modalities are imperative for the challenging management of muscle-invasive and metastatic BC to improve patient survival rates. The recently identified KMT9, an obligate heterodimer composed of KMT9α and KMT9β, regulates the growth of various types of tumors such as prostate, lung, and colon cancer. While the overexpression of KMT9α was previously observed to be associated with aggressive basal-like MIBC in an analysis of patients' tissue samples, a potential functional role of KMT9 in this type of cancer has not been investigated to date. In this study, we show that KMT9 regulates proliferation, migration, and invasion of various MIBC cell lines with different genetic mutations. KMT9α depletion results in the differential expression of genes regulating the cell cycle, cell adhesion, and migration. Differentially expressed genes include oncogenes such as EGFR and AKT1 as well as mediators of cell adhesion or migration such as DAG1 and ITGA6. Reduced cell proliferation upon KMT9α depletion is also observed in
    Language English
    Publishing date 2024-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16081532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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