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Article: Study of the Genetic Expression of Antiretroviral Restriction Factors and Acute Phase Proteins in Cattle Infected with Bovine Leukemia Virus.

González-Méndez, Ana S / Tórtora Pérez, Jorge L / Rojas-Anaya, Edith / Ramírez Álvarez, Hugo

2023 Volume 12, Issue 4

Abstract: The goal of this study was to analyze the genetic expression of antiretroviral restriction factors (ARF) and acute phase proteins (APP), as well as their correlation with proviral and viral loads in cattle with aleukemic (AL) and persistent lymphocytosis ...

Abstract	The goal of this study was to analyze the genetic expression of antiretroviral restriction factors (ARF) and acute phase proteins (APP), as well as their correlation with proviral and viral loads in cattle with aleukemic (AL) and persistent lymphocytosis (PL). Complete blood samples were collected from a herd of dairy cows, and we extracted genetic material from peripheral blood leukocytes. Absolute quantification of the expression of ARF (APOBEC-Z1, Z2, and Z3; HEXIM-1, HEXIM-2, and BST2) and APP (haptoglobin (HP), and serum amyloid A (SAA)) was performed by qPCR. Statistical significance was observed in the expression of APOBEC-Z3 in BLV-infected animals. We only found positive correlations with a strong expression of the ARF genes in the AL group. The participation of APOBEC (Z1 and Z3), HEXIM-1, and HEXIM-2 was more frequently identified in BLV-infected animals. HEXIM-2 showed active gene expression in the AL group. Although the expression of ARF in early stages of infection (AL) maintains an important participation, in late stages (PL) it seems to have little relevance.
Language	English
Publishing date	2023-03-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens12040529
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: SARS-CoV2 bilateral pneumonia: chest X-ray evolution.

Álvarez Méndez, Ana / Matía Almudévar, Paula / Álvarez Hernández, Silvia

Medicina intensiva

2020

Title translation	Neumonía bilateral por SARS-CoV2: evolución radiográfica.
Keywords	covid19
Language	Spanish
Publishing date	2020-05-16
Publishing country	Spain
Document type	Journal Article
ISSN	2173-5727
ISSN (online)	2173-5727
DOI	10.1016/j.medin.2020.03.004
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Article: Atrial Fibrillation and Diabetes Mellitus: Dangerous Liaisons or Innocent Bystanders?

Lorenzo-Almorós, Ana / Casado Cerrada, Jesús / Álvarez-Sala Walther, Luis-Antonio / Méndez Bailón, Manuel / Lorenzo González, Óscar

Journal of clinical medicine

2023 Volume 12, Issue 8

Abstract: Atrial fibrillation (AF) is the most common arrhythmia in adults and diabetes mellitus (DM) is a major risk factor for cardiovascular diseases. However, the relationship between both pathologies has not been fully documented and new evidence supports the ...

Abstract	Atrial fibrillation (AF) is the most common arrhythmia in adults and diabetes mellitus (DM) is a major risk factor for cardiovascular diseases. However, the relationship between both pathologies has not been fully documented and new evidence supports the existence of direct and independent links. In the myocardium, a combination of structural, electrical, and autonomic remodeling may lead to AF. Importantly, patients with AF and DM showed more dramatic alterations than those with AF or DM alone, particularly in mitochondrial respiration and atrial remodeling, which alters conductivity, thrombogenesis, and contractile function. In AF and DM, elevations of cytosolic Ca
Language	English
Publishing date	2023-04-14
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12082868
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Article ; Online: Presence of co-infection between bovine leukemia virus and bovine herpesvirus 1 in herds vaccinated against bovine respiratory complex.

González Méndez, Ana S / Cerón-Téllez, Fernando / Sarmiento Silva, Rosa E / Tórtora Pérez, Jorge L / Rojas-Anaya, Edith / Álvarez, Hugo Ramírez

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire

2023 Volume 87, Issue 2, Page(s) 105–109

Abstract: The aim of this study was molecular identification of bovine leukemia virus and possible co-infection with bovine respiratory disease complex (BRDC) viral agents in Mexican dairy herds. We collected 533 blood samples from cattle vaccinated against the ... ...

Abstract	The aim of this study was molecular identification of bovine leukemia virus and possible co-infection with bovine respiratory disease complex (BRDC) viral agents in Mexican dairy herds. We collected 533 blood samples from cattle vaccinated against the BRDC virus in 9 states across Mexico. Peripheral blood leukocytes were removed and genetic material was extracted to detect bovine leukemia virus (BLV), bovine herpesvirus 1 (BoHV-1), bovine viral diarrhea virus (BVDV), bovine parainfluenza virus 3 (BPIV-3), and bovine respiratory syncytial virus (BRSV) infection using polymerase chain reaction. We identified high BLV infection rates in 270 cattle (50.65%). One hundred and thirty-three cows (24.95%) tested positive for BoHV-1, of which 65 samples were positive for both viruses (BoHV-1 and BLV) and 68 were only positive for BoHV-1. Only 4 samples tested positive for BPIV-3 and no sample was positive for BVDV or BRSV. Relative risk and odds ratio analyses did not identify that the presence of BLV infection favors BoHV-1 co-infection in vaccinated herds.
MeSH term(s)	Animals ; Cattle ; Bovine Respiratory Disease Complex/prevention & control ; Coinfection/epidemiology ; Coinfection/veterinary ; Enzootic Bovine Leukosis/epidemiology ; Herpesvirus 1, Bovine/isolation & purification ; Infectious Bovine Rhinotracheitis/epidemiology ; Leukemia Virus, Bovine/isolation & purification ; Mexico/epidemiology ; Vaccination/statistics & numerical data ; Vaccination/veterinary ; Female
Language	English
Publishing date	2023-04-05
Publishing country	Canada
Document type	Journal Article
ZDB-ID	632814-3
ISSN	1928-9022 ; 0830-9000
ISSN (online)	1928-9022
ISSN	0830-9000
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Article ; Online: Burned Out, Engaged, Both, or Neither? Exploring Engagement and Burnout Profiles among Social Workers in Spain.

Lombardero-Posada, Xoán M / Murcia-Álvarez, Evelia / Aguiar-Fernández, Francisco J / Méndez-Fernández, Ana B / González-Fernández, Antonio

Social work

2023 Volume 68, Issue 2, Page(s) 131–140

Abstract: Few studies have analyzed the existence of homogeneous groups (profiles) in burnout and engagement among professionals, and none in social workers. This study with 448 social workers from Spain mainly examined their profiles in burnout and engagement and ...

Abstract	Few studies have analyzed the existence of homogeneous groups (profiles) in burnout and engagement among professionals, and none in social workers. This study with 448 social workers from Spain mainly examined their profiles in burnout and engagement and the characteristics of each profile in relevant job-related variables. Cluster analyses yielded four distinct profiles: the first, Burned Out, showed high burnout and low engagement; the second, Engaged, exhibited the inverse pattern with low burnout and high engagement; the third, Both, displayed simultaneously high burnout and high engagement; the fourth, Neither, showed low burnout and low engagement. The profiles also differed greatly in work-related variables: job demands (i.e., workload and work--family conflict), job resources (i.e., support from supervisor and coworkers), personal resources (i.e., psychological detachment and relaxation), and outcomes (i.e., intrinsic job satisfaction and intent to leave). The findings support interventions, individual and organizational, tailored to the characteristics of different groups to boost engagement and decrease burnout and turnover.
MeSH term(s)	Humans ; Social Workers ; Spain ; Social Work ; Burnout, Professional/psychology ; Family Conflict ; Job Satisfaction ; Surveys and Questionnaires
Language	English
Publishing date	2023-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	410783-4
ISSN	1545-6846 ; 0037-8046
ISSN (online)	1545-6846
ISSN	0037-8046
DOI	10.1093/sw/swad002
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Article ; Online: (-)-epicatechin treatment did not modify the thermogenic pathway in the gastrocnemius muscle of male rat offspring obeses by programming.

Tejeda, María Elena / De Los Santos, Sergio / Coral-Vázquez, Ramón Mauricio / Álvarez-Chávez, Ana / Palma Flores, Carlos / Zambrano, Elena / Méndez, Juan Pablo / Canto, Patricia

Journal of developmental origins of health and disease

2024 Volume 15, Page(s) e4

Abstract: The aim of this study was to analyse the expression of genes related to the regulation of energy metabolism in skeletal muscle tissue by comparing male offspring in two age groups [at 110 and 245 postnatal days (pnd)] from a mother with obesity induced ... ...

Abstract	The aim of this study was to analyse the expression of genes related to the regulation of energy metabolism in skeletal muscle tissue by comparing male offspring in two age groups [at 110 and 245 postnatal days (pnd)] from a mother with obesity induced by a high-fat diet and (-)-epicatechin (Epi) administration. Four groups of six male offspring from different litters were randomly selected for the control groups [C and offspring of mothers with maternal obesity (MO)] or Epi intervention groups. We evaluated the effect of Epi on gastrocnemius tissue by analysing the mRNA and protein expression levels of Fndc5/irisin, Pgc-1α, Ucp3, and Sln. Epi significantly increased the Pgc-1α protein in the MO group of offspring at 110 pnd (
MeSH term(s)	Humans ; Pregnancy ; Rats ; Male ; Female ; Animals ; Catechin/pharmacology ; Fibronectins/genetics ; Fibronectins/metabolism ; Fibronectins/pharmacology ; Muscle, Skeletal/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription Factors/pharmacology ; Obesity/drug therapy ; Obesity/metabolism ; Obesity, Maternal/metabolism ; RNA, Messenger/genetics
Chemical Substances	Catechin (8R1V1STN48) ; Fibronectins ; Transcription Factors ; RNA, Messenger
Language	English
Publishing date	2024-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2554780-X
ISSN	2040-1752 ; 2040-1744
ISSN (online)	2040-1752
ISSN	2040-1744
DOI	10.1017/S2040174424000072
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Article ; Online: Cancer-Related Fatigue and Circulating Biomarkers in Breast Cancer Survivors.

García-González, David / Romero-Elías, María / Álvarez-Bustos, Alejandro / Rosado-García, Silvia / Sánchez-López, Antonio J / Cantos, Blanca / Maximiano, Constanza / Méndez, Miriam / Méndez-Otero, Marta / Cebolla, Héctor / García-Foncillas, Jesús / Ruiz-Casado, Ana

Biological research for nursing

2023 Volume 26, Issue 2, Page(s) 270–278

Abstract: Purpose: Cancer-related fatigue (CRF) is the most common and disruptive symptom experienced by cancer survivors and because of its frequency and severity is especially worrisome in breast cancer survivors (BCS). Despite a great deal of research, the ... ...

Abstract	Purpose: Cancer-related fatigue (CRF) is the most common and disruptive symptom experienced by cancer survivors and because of its frequency and severity is especially worrisome in breast cancer survivors (BCS). Despite a great deal of research, the mechanisms underlying CRF have not been determined. The present study aims to describe associations between CRF in BCS and different blood biomarkers. Methods: A descriptive and cross-sectional study was conducted. A set of biomarkers assessing inflammation were measured in BCS: C-reactive protein (CRP), neutrophil-lymphocyte ratio (NLR), IL-1β, IL-6, IL-8, IL-10, tumor necrosis factor (TNF); HPA axis dysfunction (cortisol), autonomic dysfunction (noradrenaline); oxidative stress (8-OH deoxyguanosine); insulin resistance markers (insulin, IGF-I, IGFBP3) and sexual hormones (estrogens, progesterone, testosterone). Results: NLR ( Conclusion: Our results increase the evidence on pathophysiological mechanisms driving CRF in BCS. However, longitudinal studies are needed to explore the role of these factors as potential causal mechanisms.
MeSH term(s)	Humans ; Female ; Breast Neoplasms/complications ; Cancer Survivors ; Cross-Sectional Studies ; Hydrocortisone ; Hypothalamo-Hypophyseal System ; Pituitary-Adrenal System ; Biomarkers ; Fatigue
Chemical Substances	Hydrocortisone (WI4X0X7BPJ) ; Biomarkers
Language	English
Publishing date	2023-11-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2145107-2
ISSN	1552-4175 ; 1099-8004
ISSN (online)	1552-4175
ISSN	1099-8004
DOI	10.1177/10998004231215777
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Article: Importance of standardized palpation of the human temporomandibular joint. Wichtigkeit einer standardisierten Palpation des menschlichen Kiefergelenks

Serrano-Hernanz, Gema / Futarmal, Simple / Castrillón, Kothari Eduardo / Âlvarez-Méndez, Ana Maria / Ardizone-Garcia, Ignacio / Svensson, Peter

Journal of craniomandibular function

2023 Volume 15, Issue 1, Page(s) 9

Language	German ; English
Document type	Article
ZDB-ID	2468299-8
ISSN	1868-4149
Database	Current Contents Medicine

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Article ; Online: Social Workers' Self-Care Practices: Buffering the Influence of Work-Family Interferences on Burnout and Engagement.

Lombardero-Posada, Xoán M / Méndez-Fernández, Ana B / Aguiar-Fernández, Francisco X / Murcia-Álvarez, Evelia / González-Fernández, Antonio

Health & social work

2022 Volume 47, Issue 3, Page(s) 195–204

Abstract: As a reaction to specific job stressors, social workers can experience job burnout. The job demands-resources theory posits that personal characteristics would mediate the influence of job stressors on either burnout or engagement. Within this framework, ...

Abstract	As a reaction to specific job stressors, social workers can experience job burnout. The job demands-resources theory posits that personal characteristics would mediate the influence of job stressors on either burnout or engagement. Within this framework, this cross-sectional research aimed to analyze the relationships between work-family interferences (as predictors), self-care practices (as mediators), and burnout and engagement (as outcomes). The sample included 437 graduate social workers from Spain. Structural equation modeling showed that family-work and work-family conflicts negatively predicted self-care practices and positively predicted burnout. Professional and personal self-care practices positively predicted engagement, negatively predicted burnout, and attenuated the impact of work-family interferences on burnout and engagement. To the authors' knowledge, the present article is the first to test the job demands-resources theory with these variables on social workers. The findings support interventions for social work students and professionals enhancing self-care practices to promote engagement and to reduce burnout, and highlight the need to decrease job stressors and enhance job resources for social workers.
MeSH term(s)	Burnout, Professional ; Cross-Sectional Studies ; Humans ; Job Satisfaction ; Self Care ; Social Workers ; Surveys and Questionnaires
Language	English
Publishing date	2022-05-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	448861-1
ISSN	1545-6854 ; 0360-7283
ISSN (online)	1545-6854
ISSN	0360-7283
DOI	10.1093/hsw/hlac010
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Article ; Online: Vicarious Trauma Scale: Psychometric Properties in a Sample of Social Workers from Spain.

Aguiar-Fernández, Francisco J / Méndez-Fernández, Ana B / Lombardero-Posada, Xoán M / Murcia-Álvarez, Evelia / González-Fernández, Antonio

Health & social work

2022 Volume 47, Issue 4, Page(s) 244–252

Abstract: As a result of secondary exposure to traumatic material, social workers may experience vicarious trauma. However, the analysis of this variable among social workers is scarce. The Vicarious Trauma Scale (VTS) is a brief instrument designed to measure the ...

Abstract	As a result of secondary exposure to traumatic material, social workers may experience vicarious trauma. However, the analysis of this variable among social workers is scarce. The Vicarious Trauma Scale (VTS) is a brief instrument designed to measure the stress consequence of shared trauma. This study aims to examine the psychometrics of the VTS in a sample of 448 social workers from Spain. The results from the exploratory and confirmatory factor analyses (EFA and CFA) indicated that the VTS has satisfactory psychometric properties. Different indices of internal consistency supported the reliability of the VTS. Both EFA and CFA revealed the existence of two factors, corresponding to the cognitive and affective consequences of secondary exposure to trauma. Finally, the correlations of the VTS with other relevant and well-known job variables (workload, work-family conflict, detachment, supervisor support, burnout, and engagement) followed the expected pattern, and the VTS differentiated the social workers by their trauma caseload. Therefore, the VTS can be considered an adequate screening method of social workers' vicarious trauma, and its application recommended to examine the possible risk and protective factors and consequences.
MeSH term(s)	Humans ; Compassion Fatigue ; Psychometrics ; Social Workers ; Spain ; Reproducibility of Results ; Surveys and Questionnaires
Language	English
Publishing date	2022-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	448861-1
ISSN	1545-6854 ; 0360-7283
ISSN (online)	1545-6854
ISSN	0360-7283
DOI	10.1093/hsw/hlac026
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