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  1. Article: Hospital Clinics: Service of Prof. Donald Maclean, Medical College of University, Michigan.

    Wilson, D F

    The Dental register

    2021  Volume 35, Issue 3, Page(s) 129–130

    Language English
    Publishing date 2021-03-10
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Charles Donald O'Malley 1907-1970.

    Wilson, L G

    Journal of the history of medicine and allied sciences

    1971  Volume 26, Issue 1, Page(s) 81–86

    MeSH term(s) Historiography ; History of Medicine ; United States
    Language English
    Publishing date 1971-01
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 80280-3
    ISSN 1468-4373 ; 0022-5045
    ISSN (online) 1468-4373
    ISSN 0022-5045
    DOI 10.1093/jhmas/xxvi.1.81
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    In stock of ZB MED Cologne/Königswinter

    Ua II Zs.90: Show issues Location:
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  3. Book: Odor memory and perception

    Barkai, Edi / Wilson, Donald A.

    (Progress in brain research ; 208)

    2014  

    Author's details ed. by Edi Barkai ; Donald A. Wilson
    Series title Progress in brain research ; 208
    Collection
    Language English
    Size XVI, 354 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    Note Literaturangaben
    HBZ-ID HT018265597
    ISBN 978-0-444-63350-7 ; 0-444-63350-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 2032 available for loan (reading room) Lesesaal EG

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  4. Article ; Online: Neuroscience: Building better cognition through smell.

    Wilson, Donald A / Sullivan, Regina M

    Current biology : CB

    2023  Volume 33, Issue 20, Page(s) R1049–R1051

    Abstract: Developmental neural activity organizes sensory system development. New evidence in mice suggests postnatal olfactory bulb activity also modulates development of the structure and function of hippocampal-cortical circuits. Reducing cell-specific ... ...

    Abstract Developmental neural activity organizes sensory system development. New evidence in mice suggests postnatal olfactory bulb activity also modulates development of the structure and function of hippocampal-cortical circuits. Reducing cell-specific olfactory bulb output during an infant sensitive period impairs later-life cognition.
    MeSH term(s) Humans ; Mice ; Animals ; Smell ; Olfactory Bulb ; Neurosciences ; Cognition ; Hippocampus ; Odorants
    Language English
    Publishing date 2023-10-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2023.09.030
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    Zs.A 3208: Show issues Location:
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  5. Article ; Online: Threat Memory in the Sensory Cortex: Insights from Olfaction.

    Li, Wen / Wilson, Donald A

    The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry

    2023  , Page(s) 10738584221148994

    Abstract: The amygdala has long held the center seat in the neural basis of threat conditioning. However, a rapidly growing literature has elucidated extra-amygdala circuits in this process, highlighting the sensory cortex for its critical role in the mnemonic ... ...

    Abstract The amygdala has long held the center seat in the neural basis of threat conditioning. However, a rapidly growing literature has elucidated extra-amygdala circuits in this process, highlighting the sensory cortex for its critical role in the mnemonic aspect of the process. While this literature is largely focused on the auditory system, substantial human and rodent findings on the olfactory system have emerged. The unique nature of the olfactory neuroanatomy and its intimate association with emotion compels a review of this recent literature to illuminate its special contribution to threat memory. Here, integrating recent evidence in humans and animal models, we posit that the olfactory (piriform) cortex is a primary and necessary component of the distributed threat memory network, supporting mnemonic ensemble coding of acquired threat. We further highlight the basic circuit architecture of the piriform cortex characterized by distributed, auto-associative connections, which is prime for highly efficient content-addressable memory computing to support threat memory. Given the primordial role of the piriform cortex in cortical evolution and its simple, well-defined circuits, we propose that olfaction can be a model system for understanding (transmodal) sensory cortical mechanisms underlying threat memory.
    Language English
    Publishing date 2023-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1233753-5
    ISSN 1089-4098 ; 1073-8584
    ISSN (online) 1089-4098
    ISSN 1073-8584
    DOI 10.1177/10738584221148994
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    Zs.A 4315: Show issues Location:
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  6. Book ; Online: Habituation mechanisms and their impact on cognitive function

    Rankin, Catharine / Wilson, Donald A. / Schmid, Susanne

    2015  

    Abstract: Habituation describes the progressive decrease of the amplitude or frequency of a motor response to repeated sensory stimulation that is not caused by sensory receptor adaptation or motor fatigue. Habituation can occur in different time scales: ... ...

    Abstract Habituation describes the progressive decrease of the amplitude or frequency of a motor response to repeated sensory stimulation that is not caused by sensory receptor adaptation or motor fatigue. Habituation can occur in different time scales: habituation within a testing session has been termed short-term habituation, whereas habituation across testing sessions has been termed long-term habituation. Generally, the more spaced the stimuli for inducing habituation are presented (i.e. the slower habituation is induced), the longer it seems to take to recover the behavioural response to its initial magnitude. Habituation is opposed by behavioural sensitization, which is thought to be an independent mechanism that leads to an increased behavioural response, especially if the sensory stimulus is annoying or aversive.-

    Habituation provides an important mechanism for filtering sensory information, as it allows filtering out irrelevant stimuli and thereby focussing on important stimuli, a prerequisite for many cognitive tasks. The importance is demonstrated in mental disorders that are associated with disruptions in habituation, e.g. schizophrenia and autism spectrum disorders. The inability to filter out irrelevant information in patients with these disorders strongly correlates with disruptions in higher cognitive functions, such as in different types of memory and attention. Habituation is also considered to be the most basic form of non-associative implicit learning, and it can be observed throughout the animal kingdom. Based on the importance of habituation for cognitive function and therefore for the survival of an animal, it is assumed that habituation mechanisms are highly conserved across species.-

    On the other hand, there is emerging evidence for a multitude of homo- and heterosynaptic mechanisms underlying habituation, depending on the modality of sensory stimulation, the level of sensory information processing where habituation occurs, and the temporal composition of sensory stimulation. Eric Kandel used the sea hare Aplysia in order to study habituation mechanisms of the gill withdrawal reflex; however, the molecular mechanisms remain largely elusive to date. A multitude of different organisms, behaviours, and experimental approaches have been used since in order to study habituation, but still surprisingly little is known about the underlying mechanisms. New insights also come from an unexpected side: in the recent past, groups that have been studying molecular mechanisms underlying short- and long-term synaptic plasticity phenomenons in different parts of the rodent brain are starting to link these plasticity processes to behavioural habituation.-
    Keywords Neurosciences. Biological psychiatry. Neuropsychiatry ; Science (General)
    Size 1 electronic resource (110 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020091031
    ISBN 9782889194629 ; 2889194620
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article ; Online: Good scents: A short road from olfaction to satisfaction.

    Wilson, Donald A / East, Brett S

    Current biology : CB

    2021  Volume 31, Issue 8, Page(s) R374–R376

    Abstract: We rapidly classify odors as pleasant or aversive, but the brain circuits underlying how odors motivate approach and avoidance responses are largely unknown. New research describes a direct path from the olfactory bulb to ventral striatum driving odor- ... ...

    Abstract We rapidly classify odors as pleasant or aversive, but the brain circuits underlying how odors motivate approach and avoidance responses are largely unknown. New research describes a direct path from the olfactory bulb to ventral striatum driving odor-mediated reward.
    MeSH term(s) Odorants ; Personal Satisfaction ; Smell
    Language English
    Publishing date 2021-04-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2021.01.099
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  8. Article ; Online: Developmental alcohol exposure is exhausting: Sleep and the enduring consequences of alcohol exposure during development.

    Wilson, Donald A / Sullivan, Regina M / Smiley, John F / Saito, Mariko / Raineki, Charlis

    Neuroscience and biobehavioral reviews

    2024  Volume 158, Page(s) 105567

    Abstract: Prenatal alcohol exposure is the leading nongenetic cause of human intellectual impairment. The long-term impacts of prenatal alcohol exposure on health and well-being are diverse, including neuropathology leading to behavioral, cognitive, and emotional ... ...

    Abstract Prenatal alcohol exposure is the leading nongenetic cause of human intellectual impairment. The long-term impacts of prenatal alcohol exposure on health and well-being are diverse, including neuropathology leading to behavioral, cognitive, and emotional impairments. Additionally negative effects also occur on the physiological level, such as the endocrine, cardiovascular, and immune systems. Among these diverse impacts is sleep disruption. In this review, we describe how prenatal alcohol exposure affects sleep, and potential mechanisms of those effects. Furthermore, we outline the evidence that sleep disruption across the lifespan may be a mediator of some cognitive and behavioral impacts of developmental alcohol exposure, and thus may represent a promising target for treatment.
    MeSH term(s) Female ; Humans ; Pregnancy ; Fetal Alcohol Spectrum Disorders/etiology ; Prenatal Exposure Delayed Effects ; Ethanol/adverse effects ; Sleep
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 282464-4
    ISSN 1873-7528 ; 0149-7634
    ISSN (online) 1873-7528
    ISSN 0149-7634
    DOI 10.1016/j.neubiorev.2024.105567
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    Zs.A 1371: Show issues Location:
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  9. Book ; Online: Olfactory memory networks: from emotional learning to social behaviors

    Ravel, Nadine / Wilson, Donald A. / Sullivan, Regina M. / Mouly, Anne-Marie

    2015  

    Abstract: Odors are powerful stimuli that can evoke emotional states, and support learning and memory. Decades of research have indicated that the neural basis for this strong odor-emotional memory connection is due to the uniqueness of the anatomy of the ... ...

    Abstract Odors are powerful stimuli that can evoke emotional states, and support learning and memory. Decades of research have indicated that the neural basis for this strong odor-emotional memory connection is due to the uniqueness of the anatomy of the olfactory pathways. Indeed, unlike the other sensory systems, the sense of smell does not pass through the thalamus to be routed to the cortex. Rather, odor information is relayed directly to the limbic system, a brain region typically associated with memory and emotional processes. This provides olfaction with a unique and potent power to influence mood, acquisition of new information, and use of information in many different contexts including social interactions.-

    Indeed, olfaction is crucially involved in behaviors essential for survival of the individual and species, including identification of predators, recognition of individuals for procreation or social hierarchy, location of food, as well as attachment between mating pairs and infant-caretaker dyads. Importantly, odors are sampled through sniffing behavior. This active sensing plays an important role in exploratory behaviors observed in the different contexts mentioned above. Odors are also critical for learning and memory about events and places and constitute efficient retrieval cues for the recall of emotional episodic memories. This broad role for odors appears highly preserved across species. In addition, the consistent early developmental emergence of olfactory function across diverse species also provides a unique window of opportunity for analysis of myriad behavioral systems from rodents to nonhuman primates and humans.-

    This, when combined with the relatively conserved organization of the olfactory system in mammals, provides a powerful framework to explore how complex behaviors can be modulated by odors to produce adaptive responses, and to investigate the underlying neural networks. The present research topic brings together cutting edge research on diverse species and developmental stages, highlighting convergence and divergence between humans and animals to facilitate translational research
    Keywords Neurosciences. Biological psychiatry. Neuropsychiatry ; Science (General)
    Size 1 electronic resource (288 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090048
    ISBN 9782889194865 ; 2889194868
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Book: Learning to smell

    Wilson, Donald A. / Stevenson, Richard J.

    olfactory perception from neurobiology to behavior

    2006  

    Author's details Donald A. Wilson & Richard J. Stevenson
    Keywords Smell / physiology ; Perception ; Olfactory Nerve / physiology ; Odors ; Smell
    Subject code 612.86
    Language English
    Size IX, 309 S. : Ill., graph. Darst., 24cm
    Publisher Johns Hopkins Univ. Press
    Publishing place Baltimore, Md
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index. - Formerly CIP
    HBZ-ID HT014954403
    ISBN 0-8018-8368-7 ; 978-0-8018-8368-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 2998 order for loan Magazin

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