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Article: Determinants of Health-related Quality of Life in Persons with Epilepsy Seen at a Tertiary Hospital in North Western Nigeria.

Iwuozo, E U / Obiako, O R / Onyemocho, A / Ogunniyi, A

2020 Volume 37, Issue 5, Page(s) 475–480

Abstract: Introduction: There is a growing global concern about the effect of epilepsy on the Health-Related Quality of Life (HRQoL) of the sufferers.: Aim: This study assessed the determinants of HRQoL in persons with epilepsy (PWE) in a tertiary hospital in ... ...

Abstract	Introduction: There is a growing global concern about the effect of epilepsy on the Health-Related Quality of Life (HRQoL) of the sufferers. Aim: This study assessed the determinants of HRQoL in persons with epilepsy (PWE) in a tertiary hospital in North Western Nigeria. Methodology: A cross-sectional study was carried out on 103 patients with epilepsy aged ≥ 18 years attending Neurology clinic. Ethical clearance was obtained from the Health Research Ethics Committee of the institution. The short version of the World Health Organization Quality of Life questionnaire (WHOQOL-BREF) was administered to the participants. Statistical significance was set with p value at 0.05. The determinants of HRQoL was obtained by using univariate and subsequent multivariate logistic regression analysis. Result: The mean age of patients was 33.4±15.8 years. There were 54(52.4%) males and 49 (47.6%) females. The significant determinants of HRQoLfound were time of last seizure episode (OR = 7.50, 95% CI = 1.36 -41.20, p = 0.021) and social support (OR = 21.5, 95% CI = 3.67 - 125.68, p = 0.001). Following multivariate logistic regression analysis, social support (OR = 29.51, 95% CI = 2.87 - 302.66, p = 0.004) appeared as the independent determinant of HRQoLin PWE. Conclusion: Social support was the main determining factor of HRQoL in epilepsy patients in this study. Therefore there is the need to ensure a comprehensive care which should include health education, adequate seizure control and social support for epilepsy patients to improve their HRQoL.
MeSH term(s)	Adolescent ; Adult ; Cross-Sectional Studies ; Epilepsy ; Female ; Humans ; Male ; Middle Aged ; Nigeria ; Quality of Life ; Surveys and Questionnaires ; Tertiary Care Centers ; Young Adult
Language	English
Publishing date	2020-10-15
Publishing country	Nigeria
Document type	Journal Article
ZDB-ID	1132088-6
ISSN	0189-160X
ISSN	0189-160X
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Zs.A 3527: Show issues

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Article ; Online: Knowledge and perspectives of community members on risk assessment for stroke prevention using mobile health approaches in Nigeria.

Sarfo, Fred Stephen / Obiako, Reginald / Nichols, Michelle / Akinyemi, Joshua Odunayo / Fakunle, Adekunle / Akpa, Onoja / Arulogun, Oyedunni / Akinyemi, Rufus / Jenkins, Carolyn / Ovbiagele, Bruce / Owolabi, Mayowa

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

2023 Volume 32, Issue 9, Page(s) 107265

Abstract: Objectives: To assess the knowledge of community dwelling adults on stroke risk and their willingness to use mobile health (mHealth) technology in assessing their stroke risk.: Materials and methods: A cross-sectional study was conducted among adults ...

Abstract	Objectives: To assess the knowledge of community dwelling adults on stroke risk and their willingness to use mobile health (mHealth) technology in assessing their stroke risk. Materials and methods: A cross-sectional study was conducted among adults (≥18 years old) using survey questionnaires designed by neurologists and health promotion experts and administered by trained study staff. Logistic regression models were used to assess factors associated with receptivity toward knowing individual stroke risk score and willingness to use a mobile application (App) to assess stroke risk. Results: The survey was administered to 486 participants in Nigeria, with a mean age of 47.4 ± 15.5 years, comprising 53.5% females. Up to 84% of participants wanted to know their risk for developing stroke but only 29.6% of respondents had ever previously had their stroke risk assessed. Factors associated with willingness to know stroke risk were age [aOR (95% CI): 0.97 (0.95 - 0.99)], and Hausa tribe [16.68 (2.16 - 128.92)]. Up to 66% of participants wanted to know their immediate risk of stroke, compared with 6.6% and 2.1% who wanted to know their 5-year or 10-year future stroke risks respectively. Regarding locations, participants preferred stroke risk assessment to be performed at a health facility, at home by health professional, on their own using mHealth (stroke risk calculator application), or at communal gatherings (decreasing order). About 70% specifically wished to learn about their stroke risk via an mHealth application. Conclusions: Community dwelling Nigerians wanted to know their immediate risk of stroke using digital platforms, such as a mobile phone stroke risk calculator application. Clinical trials are needed to assess the effectiveness of such a strategy for primary prevention of stroke in sub-Saharan African communities.
MeSH term(s)	Adult ; Female ; Humans ; Middle Aged ; Adolescent ; Male ; Cross-Sectional Studies ; Nigeria/epidemiology ; Telemedicine ; Risk Assessment ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/prevention & control
Language	English
Publishing date	2023-07-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	1131675-5
ISSN	1532-8511 ; 1052-3057
ISSN (online)	1532-8511
ISSN	1052-3057
DOI	10.1016/j.jstrokecerebrovasdis.2023.107265
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Article: Effect of Epilepsy and Antiepileptic Drugs Therapy on Erythrocyte Malondialdehyde and Some Antioxidants in Persons with Epilepsy.

Iwuozo, E U / Obiako, O R / Ejiofor, J I / Kehinde, J A / Abubakar, S A

West African journal of medicine

2019 Volume 36, Issue 3, Page(s) 211–216

Abstract: Background: Antiepileptic drugs are necessary for successful treatment of epilepsy. Unfortunately, epilepsy itself and some antiepileptic drugs have been documented to provoke or worsen seizure frequency by altering blood levels of some oxidants and ... ...

Abstract	Background: Antiepileptic drugs are necessary for successful treatment of epilepsy. Unfortunately, epilepsy itself and some antiepileptic drugs have been documented to provoke or worsen seizure frequency by altering blood levels of some oxidants and antioxidants in persons with epilepsy. Objective: This study investigated the effect of epilepsy and antiepileptic drugs on blood levels of some oxidants and antioxidants. Methodology: This was a cross-sectional case-control study. Blood samples were obtained from 35 antiepileptic drug-experienced persons with epilepsy; 35 antiepileptic-naıve persons with epilepsy; and 35 age- and- sex matched apparently healthy controls; and analysed for malondialdehyde and antioxidants (uric acid, superoxide dismutase, glutathione peroxidase and catalase) using enzyme-linked immunosorbent assay. Results: One-hundred and five (105) subjects (35 patients on antiepileptic drugs, 35 newly diagnosed, antiepileptic drug-naive and 35 healthy controls) were investigated. The median ages of antiepileptic drug-experienced, antiepileptic drug-naıve and healthy participants were 30.0, 26.0 and 37.0 years respectively. Persons with epilepsy had significantly higher blood levels of malondialdehyde and uric acid and lower levels of enzymatic antioxidants than healthy controls. Also, persons with epilepsy on antiepileptic drug polytherapy had signi-ficantly higher blood levels of malondialdehyde and uric acid and lower levels of enzymatic antioxidants than antiepileptic drug-naıve persons with epilepsy and persons with epilepsy on antiepileptic drug monotherapy respectively. Conclusion: Epilepsy and antiepileptic drug significantly altered blood levels of malondialdehyde, uric acid and enzymatic antioxidants and/or their homeostatic kinetics.
MeSH term(s)	Adult ; Anticonvulsants/therapeutic use ; Antioxidants/analysis ; Antioxidants/metabolism ; Case-Control Studies ; Cross-Sectional Studies ; Epilepsy/blood ; Epilepsy/drug therapy ; Erythrocytes/metabolism ; Humans ; Malondialdehyde/blood
Chemical Substances	Anticonvulsants ; Antioxidants ; Malondialdehyde (4Y8F71G49Q)
Language	English
Publishing date	2019-10-31
Publishing country	Nigeria
Document type	Journal Article
ZDB-ID	1132088-6
ISSN	0189-160X
ISSN	0189-160X
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Article: Challenges of HIV treatment in resource-poor countries: a review.

Obiako, O R / Muktar, H M

Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria

2011 Volume 19, Issue 4, Page(s) 361–368

Abstract: Background: The human immunodeficiency virus/acquired immunodeficiency syndrome pandemic have posed a significant public health challenge to the global community. Massive therapeutic interventions with antiretroviral drugs are being undertaken, yet ... ...

Abstract	Background: The human immunodeficiency virus/acquired immunodeficiency syndrome pandemic have posed a significant public health challenge to the global community. Massive therapeutic interventions with antiretroviral drugs are being undertaken, yet problems and challenges exist. This review examines these problems and challenges as they affect the treatment of HIV infection in resource-poor countries such as Nigeria. Methods: The information was sourced from relevant literature using human immunodeficiency virus/acquired immunodeficiency syndrome journals, textbooks and Websites on human immunodeficiency virus/acquired immunodeficiency syndrome, highly active antiretroviral therapy, resource-poor countries as key words. Results: Several studies have shown that the advent of highly active antiretroviral therapy in 1996 has significantly reduced morbidity and mortality among people living with HIV/AIDS (PLWHA). But in resource-poor countries, initiation and maintenance of highly active antiretroviral therapy has been associated with many challenges and problems such as: poor infrastructural base for the control programs; irregular or non availability of drugs; poor drug adherence; co-morbidities and opportunistic infections/malignancies; drug toxicities; drug/food and drug/drug interactions; laboratory monitoring of viral load; CD4 cell counts; full blood counts; electrolytes, kidney and liver functions. Conclusion: The review has shown that the solution to the pandemic lies in a multi-sectoral and holistic approach involving International and local agencies, and communities.
MeSH term(s)	Acquired Immunodeficiency Syndrome/drug therapy ; Acquired Immunodeficiency Syndrome/economics ; Acquired Immunodeficiency Syndrome/virology ; Anti-Retroviral Agents/adverse effects ; Anti-Retroviral Agents/economics ; Antiretroviral Therapy, Highly Active ; Developing Countries ; HIV ; HIV Infections/drug therapy ; Health Resources ; Health Services Accessibility ; Health Services Needs and Demand ; Humans ; Nigeria
Chemical Substances	Anti-Retroviral Agents
Language	English
Publishing date	2011-04-28
Publishing country	Nigeria
Document type	Journal Article ; Review
ISSN	1115-2613
ISSN	1115-2613
DOI	10.4314/njm.v19i4.69785
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Article ; Online: Effect of an Educational Intervention for Primary Stroke Risk Reduction in Ghana and Nigeria: Pilot Randomized Controlled Trial.

Sarfo, Fred Stephen / Akinyemi, Joshua Odunayo / Obiako, Reginald / Nichols, Michelle / Fakunle, Adekunle Gregory / Adusei, Nathaniel / Ampofo, Michael / Arulogun, Oyedunni / Jenkins, Carolyn / Akpa, Onoja M / Aribisala, Benjamin / Abdulrasaq, Saheed / Akinyemi, Rufus / Ovbiagele, Bruce / Owolabi, Mayowa O

Stroke

2023 Volume 54, Issue 6, Page(s) 1660–1664

Abstract: Background: Using tailored mobile health interventions to improve global vascular risk awareness and control is yet to be investigated for primary stroke prevention in Africa.: Methods: This 2-arm pilot randomized controlled trial involved 100 stroke- ...

Abstract	Background: Using tailored mobile health interventions to improve global vascular risk awareness and control is yet to be investigated for primary stroke prevention in Africa. Methods: This 2-arm pilot randomized controlled trial involved 100 stroke-free adults with at least 2 vascular risk factors for stroke. Eligible participants were assigned randomly to a control arm offering 1-time counseling (n=50) or a 2-month educational intervention arm (n=50) comprising a stroke video and riskometer app aimed at improving stroke risk factor awareness and health-seeking behavioral modification to control total vascular risk. Reduction in total stroke risk score was the primary outcome while feasibility and process measures were secondary outcomes. Results: All enrolled participants completed the 2-month follow-up (retention rate=100%). The mean (SD) age of participants was 59.5 (±12.5) years, 38% were males. The mean change in stroke risk score at 2 months was -11.9% (±14.2) in the intervention arm versus -1.2% (±9.1) in the control arm, Conclusions: The intervention demonstrated a positive signal of effect over a 2-month period. A definitive clinical trial with a longer duration of follow-up is warranted on the premise of these promising findings from this pilot randomized clinical trial. Registration: URL: https://www. Clinicaltrials: gov; Unique identifier: NCT05619406.
MeSH term(s)	Male ; Adult ; Humans ; Middle Aged ; Aged ; Female ; Pilot Projects ; Ghana/epidemiology ; Nigeria/epidemiology ; Stroke/epidemiology ; Stroke/prevention & control ; Stroke/complications ; Risk Reduction Behavior
Language	English
Publishing date	2023-05-04
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	80381-9
ISSN	1524-4628 ; 0039-2499 ; 0749-7954
ISSN (online)	1524-4628
ISSN	0039-2499 ; 0749-7954
DOI	10.1161/STROKEAHA.123.042618
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Article ; Online: Capacity-Building for Stroke Genomic Research Data Collection: The African Neurobiobank Ethical, Legal, and Social Implications Project Experience.

Uvere, Ezinne O / Nichols, Michelle / Ojebuyi, Babatunde R / Isah, Suleiman Yahaya / Calys-Tagoe, Benedict / Jenkins, Carolyn / Obiako, Reginald / Owolabi, Lukman / Akpalu, Albert / Sarfo, Fred Stephen / Ogunronbi, Olumayowa / Adigun, Muyiwa / Fakunle, Gregory Adekunle / Hamzat, Bello / Laryea, Ruth / Uthman, Babatunde / Akinyemi, Joshua O / Adeleye, Osi / Melikam, Lois /

Balogun, Olubukola / Sule, Abdullateef / Adeniyi, Sunday / Asibey, Shadrack O / Oguike, Wisdom / Olorunsogbon, Olorunyomi / Singh, Arti / Titiloye, Musibau A / Musbahu, Rabiu / Wahab, Kolawole W / Kalaria, Rajesh N / Jegede, Ayodele S / Owolabi, Mayowa O / Ovbiagele, Bruce / Arulogun, Oyedunni S / Akinyemi, Rufus O

Biopreservation and biobanking

2022 Volume 21, Issue 2, Page(s) 158–165

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Humans ; Biological Specimen Banks ; Capacity Building ; Genomics ; Community-Based Participatory Research ; Africa
Language	English
Publishing date	2022-06-27
Publishing country	United States
Document type	Multicenter Study ; Journal Article
ZDB-ID	2593993-2
ISSN	1947-5543 ; 1947-5535
ISSN (online)	1947-5543
ISSN	1947-5535
DOI	10.1089/bio.2021.0144
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Article: Blood pressure control in long-term stroke survivors evaluated one year post stroke.

Abubakar, S A / Obiako, O R / Isa, M S / Jamoy, B Y

The Nigerian postgraduate medical journal

2015 Volume 22, Issue 1, Page(s) 56–60

Abstract: Aims and objectives: Hypertension is the most common modifiable risk factor for stroke and treatment of hypertension has been known to reduce the risk of recurrent stroke. There are no studies done to evaluate the optimal blood pressure (BP) control in ... ...

Abstract	Aims and objectives: Hypertension is the most common modifiable risk factor for stroke and treatment of hypertension has been known to reduce the risk of recurrent stroke. There are no studies done to evaluate the optimal blood pressure (BP) control in long-term stroke survivors in Nigeria. This study is aimed at determining the proportion of stroke survivors attending stroke prevention clinic who have optimal BP control of hypertension one year post stroke and to determine what factors are associated with the suboptimal BP control. Patients and methods: The subjects were consecutively presenting long term stroke survivors attending Neurology Outpatients'Clinic of Ahmadu Bello University Teaching Hospital (ABUTH), Zaria. After informed consent, socio-demographic data and clinical characteristic were obtained from the patient using structured questionnaire. Admission stroke severity was obtained retrospectively using National Institute of Health Stroke Score (NIHSS). Modified Rankin scale (mRs) was used to assess the level of handicap . The presence of depression was determined using the Hamilton Depression Rating Scale (HDRS). Blood pressure was measured in the dominant, non-stroke arm of the patients using mercury sphygmomanometer. Results: A total of 68 patients were studied with a mean age of 55.15±11.9 years. Most common co- morbid condition was diabetes mellitus. Only 3(4.4%) patients had a repeat stroke during the one year period. Twenty five (36.8%) of these patients still had sub-optimal BP control. Forty seven (69.1%) of these patients were on combination therapy (including angiotensin converting enzyme inhibitors and diuretics) and 18 (26.5%) were on calcium channel blockers alone. The difference in mean age of stroke survivors with optimal and sub-optima BP control was not statistically significant. However, the mean duration of formal education of the stroke survivors with optimally controlled blood pressure was significantly higher than those with sub-optimal BP control. Eighteen (26.5%) of long term stroke survivors had clinical depression. Significantly higher proportion of the clinically depressed patients had sub-optimal blood pressure at one year compared to those that were not depressed. Formally educated patients had a better blood pressure control compared to those without formal education. Following a multivariate logistic regression, the major independent determinants of sub-optimal blood pressure control at one year post stroke were presence of depression and low levels of formal educational attainment. Conclusion: majority of stroke survivors attending the ABUTH neurology outpatients clinic have suboptimal blood pressure control and major determinant of suboptimal BP control were presence of clinical depression and low formal educational status.
Language	English
Publishing date	2015-03
Publishing country	Nigeria
Document type	Journal Article
ZDB-ID	2171096-X
ISSN	1117-1936
ISSN	1117-1936
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Article ; Online: Stroke occurrence by hypertension treatment status in Ghana and Nigeria: A case-control study.

Sarfo, Fred Stephen / Asowata, Osahon Jeffery / Akpa, Onoja Matthew / Akinyemi, Joshua / Wahab, Kolawole / Singh, Arti / Akpalu, Albert / Opare-Addo, Priscilla Abrafi / Okekunle, Akinkunmi Paul / Ogbole, Godwin / Fakunle, Adekunle / Adebayo, Oladimeji / Obiako, Reginald / Akisanya, Cynthia / Komolafe, Morenkeji / Olunuga, Taiwo / Chukwuonye, Innocent I / Osaigbovo, Godwin / Olowoyo, Paul /

Adebayo, Phillip B / Jenkins, Carolyn / Bello, Abiodun / Laryea, Ruth / Ibinaye, Phillip / Olalusi, Olatundun / Adeniyi, Sunday / Arulogun, Oyedunni / Ogah, Okechukwu / Adeoye, Abiodun / Samuel, Dialla / Calys-Tagoe, Benedit / Tiwari, Hemant / Obiageli, Onyemelukwe / Mensah, Yaw / Appiah, Lambert / Akinyemi, Rufus / Ovbiagele, Bruce / Owolabi, Mayowa

Journal of the neurological sciences

2024 Volume 459, Page(s) 122968

Abstract: Background: Hypertension is preeminent among the vascular risk factors for stroke occurrence. The wide gaps in awareness, detection, treatment, and control rates of hypertension are fueling an epidemic of stroke in sub-Saharan Africa.: Purpose: To ... ...

Abstract	Background: Hypertension is preeminent among the vascular risk factors for stroke occurrence. The wide gaps in awareness, detection, treatment, and control rates of hypertension are fueling an epidemic of stroke in sub-Saharan Africa. Purpose: To quantify the contribution of untreated, treated but uncontrolled, and controlled hypertension to stroke occurrence in Ghana and Nigeria. Methods: The Stroke Investigative Research and Educational Network (SIREN) is a case-control study across 16 study sites in Ghana and Nigeria. Cases were acute stroke (n = 3684) with age- and sex-matched stroke-free controls (n = 3684). We evaluated the associations of untreated hypertension, treated but uncontrolled hypertension, and controlled hypertension at BP of <140/90 mmHg with risk of stroke occurrence. We assessed the adjusted odds ratio and population-attributable risk of hypertension treatment control status associated with stroke occurrence. Results: The frequencies of no hypertension, untreated hypertension, treated but uncontrolled hypertension and controlled hypertension among stroke cases were 4.0%, 47.7%, 37.1%, and 9.2% vs 40.7%, 34.9%, 15.9%, and 7.7% respectively among stroke-free controls, p < 0.0001. The aOR and PAR (95% CI) for untreated hypertension were 6.58 (5.15-8.41) and 35.4% (33.4-37.4); treated but uncontrolled hypertension was 9.95 (7.60-13.02) and 35.9% (34.2-37.5); and controlled hypertension 5.37 (3.90-7.41) and 8.5% (7.6-9.5) respectively. Untreated hypertension contributed a PAR of 47.5% to the occurrence of intracerebral hemorrhage vs 29.5% for ischemic stroke. The aOR of untreated hypertension for stroke occurrence was 13.31 (7.64-23.19) for <50 years; 7.14 (4.51-11.31) for 50-64 years; and 3.48 (2.28-5.30) for 65 years or more. Conclusion: The contribution of untreated hypertension and treated but uncontrolled hypertension to stroke occurrence among indigenous Africans is substantial. Implementing targeted interventions that address gaps in hypertension prevention and treatment, involving the local population, healthcare providers, and policymakers, can potentially substantially reduce the escalating burden of strokes in Africa.
MeSH term(s)	Humans ; Ghana/epidemiology ; Nigeria/epidemiology ; Case-Control Studies ; Stroke/epidemiology ; Stroke/therapy ; Stroke/etiology ; Risk Factors ; Hypertension/epidemiology ; Hypertension/complications
Language	English
Publishing date	2024-03-17
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	80160-4
ISSN	1878-5883 ; 0022-510X ; 0374-8642
ISSN (online)	1878-5883
ISSN	0022-510X ; 0374-8642
DOI	10.1016/j.jns.2024.122968
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Article ; Online: Dietary patterns associated with hypertension among stroke-free indigenous Africans: insights from the Stroke Investigative Research and Educational Network study.

Okekunle, Akinkunmi Paul / Asowata, Osahon Jeffery / Akpa, Onoja Matthew / Fakunle, Adekunle Gregory / Bodunde, Ifeoluwa / Komolafe, Morenikeji / Arulogun, Oyedunni / Sarfo, Fred Stephen / Obiako, Reginald / Osaigbovo, Godwin / Ogbole, Godwin / Bello, Abiodun / Adeniyi, Sunday / Calys-Tagoe, Benedict / Appiah, Lambert / Jenkins, Carolyn / Oyinloye, Olalekan / Dambatta, Hamisu / Balogun, Olayemi /

Singh, Arti / Olalere, Abimbola / Mensah, Yaw / Ogah, Okechukwu S / Ibinaiye, Philip / Adebayo, Oladimeji / Adebajo, Olayinka / Adebayo, Philip / Chukwuonye, Ijezie / Akinyemi, Rufus / Ovbiagele, Bruce / Owolabi, Mayowa

Journal of hypertension

2024 Volume 42, Issue 4, Page(s) 620–628

Abstract: Background: The dietary factors associated with the high burden of hypertension among indigenous Africans remain poorly understood. We assessed the relationship between dietary patterns and hypertension among indigenous Africans.: Method: In this ... ...

Abstract	Background: The dietary factors associated with the high burden of hypertension among indigenous Africans remain poorly understood. We assessed the relationship between dietary patterns and hypertension among indigenous Africans. Method: In this study, 1550 participants with hypertension matched (for age: ± 5 years, sex and ethnicity) with 1550 participants without hypertension were identified from the stroke-free population in the Stroke Investigative Research and Educational Network study in Ghana and Nigeria. Food consumption was assessed using a food frequency questionnaire, and dietary information was summarized using principal component analysis to identify seven dietary patterns. Conditional logistic regression was applied to compute the odds ratio (OR) and 95% confidence interval (CI) for the risk of hypertension by tertiles of dietary patterns adjusting for age, education, income, smoking, alcohol use, physical inactivity, family history of cardiovascular diseases, obesity and salt intake at a two-sided P less than 0.05. Results: Multivariable-adjusted OR [95% confidence interval (CI)] for risk of hypertension by second and third tertiles [using the lowest (first) tertile as reference] of dietary patterns were 0.62 (0.48-0.80), 0.70 (0.54-0.90) for whole grains and fruit drinks; 0.87 (0.68-1.12), 0.83 (0.64-1.08) for fruits; 0.85 (0.65-1.10), 0.97 (0.75-1.26) for vegetables, legumes and potatoes; 0.78 (0.60-1.00), 0.84 (0.65-1.08) for fried foods and sweetened drinks; 1.13 (0.88-1.45), 0.80 (0.62-1.03) for poultry product and organ meat; 1.11 (0.86-1.43), 0.88 (0.68-1.14) for red meat; and 1.14 (0.88-1.48), 1.09 (0.84-1.43) for processed foods ( P < 0.05). Conclusion: A higher adherence to dietary consumption of whole grains and fruits was inversely associated with low odds of hypertension in this population.
MeSH term(s)	Humans ; Dietary Patterns ; Diet/adverse effects ; Vegetables ; Fruit ; Stroke/epidemiology ; Hypertension/epidemiology ; Feeding Behavior ; Risk Factors
Language	English
Publishing date	2024-01-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605532-1
ISSN	1473-5598 ; 0263-6352 ; 0952-1178
ISSN (online)	1473-5598
ISSN	0263-6352 ; 0952-1178
DOI	10.1097/HJH.0000000000003662
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Article ; Online: Dermatomyositis associated with HIV-1 infection in a Nigerian adult female: a case report.

Ogoina, D / Umar, A / Obiako, O R

African health sciences

2012 Volume 12, Issue 1, Page(s) 74–76

Abstract: Human immunodeficiency virus (HIV) infection has been implicated as a trigger for various autoimmune diseases, one of which is dermatomyositis. This is a very rare autoimmune disease characterised by myopathy, typical cutaneous signs and variable ... ...

Abstract	Human immunodeficiency virus (HIV) infection has been implicated as a trigger for various autoimmune diseases, one of which is dermatomyositis. This is a very rare autoimmune disease characterised by myopathy, typical cutaneous signs and variable systemic manifestations. To our knowledge, the association of this rare disease with HIV infection has not been previously reported in Nigeria. We therefore decided to report the case of a 40 year old HIV-1 infected Nigerian female who presented to us with muscle, skin, and systemic manifestations of dermatomyositis. Our aim is to show the effect of HIV infection, as well as HAART-induced immune reconstitution on the clinical course of dermatomyositis.
MeSH term(s)	Adult ; Anti-Inflammatory Agents/therapeutic use ; Antiretroviral Therapy, Highly Active/adverse effects ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/drug therapy ; Autoimmune Diseases/etiology ; Dermatomyositis/diagnosis ; Dermatomyositis/drug therapy ; Dermatomyositis/etiology ; Diclofenac/therapeutic use ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Infections/immunology ; HIV-1 ; Humans ; Immune Reconstitution Inflammatory Syndrome/chemically induced ; Nigeria ; Prednisolone/therapeutic use ; Treatment Outcome
Chemical Substances	Anti-Inflammatory Agents ; Diclofenac (144O8QL0L1) ; Prednisolone (9PHQ9Y1OLM)
Language	English
Publishing date	2012-08-20
Publishing country	Uganda
Document type	Case Reports ; Journal Article
ZDB-ID	2240308-5
ISSN	1729-0503 ; 1680-6905
ISSN (online)	1729-0503
ISSN	1680-6905
Database	MEDical Literature Analysis and Retrieval System OnLINE

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