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  1. Book ; Thesis: (Früh-)diagnose neurodegenerativer Erkrankungen

    Jesse, Sarah

    proteomische Lösungsansätze

    2015  

    Author's details vorgelegt von Dr. med. Sarah Jesse
    Language German ; English
    Size 38 Blätter, cairca 70 verschieden gezählte Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Ulm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Universität Ulm, 2015
    Note Enthält Sonderabdrucke aus verschiedenen Zeitschriften in englischer Sprache
    HBZ-ID HT019124905
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Behavioral healthcare and technology

    Marsch, Lisa A. / Lord, Sarah E. / Dallery, Jesse

    using science-based innovations to transform practice

    2015  

    Author's details ed. by Lisa A. Marsch ; Sarah E. Lord ; Jesse Dallery
    Keywords Mental Disorders / therapy ; Biomedical Technology ; Mental Health Services / organization & administration
    Language English
    Size XVI, 348 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references ; Technology and the stage model of behavioral intervention development / Lisa S. Onken, Varda Shoham -- Theoretical models to inform technology-based health behavior interventions / William T. Riley -- Behavioral monitoring and assessment via sensing technologies / Santosh Kumar, J. Gayle Beck, Emre Ertin, Marcia Scott -- Technology-based behavioral interventions for alcohol and drug use problems / Aimee Campbell, Frederick Muench, Edward V. Nunes -- Using behavioral intervention technologies to reduce the burden of mood and anxiety disorders / Stephen M. Schueller, Miraj Chokshi, David C. Mohr -- Technologies for people with serious mental illness / Dror Ben-Zeev, Robert E. Drake, Rachel M. Brian -- Applying technology to medication management and adherence / Leah L. Zullig, Ryan J. Shaw, Hayden B. Bosworth -- Technological approaches to assess and treat cigarette smoking / Jesse Dallery, Sarah Martner --^ ; Technology-based interventions to promote diet, exercise and weight control / Deborah Tate, Carmina Valle -- Evidence-based approaches to harnessing technology to provide social-emotional support / Timothy Bickmore -- mHealth analytics / Daniel M. Smith, Theodore A. Walls -- Research designs to develop and evaluate technology-based health behavior interventions / Jesse Dallery, William Riley, Inbal Nahum-Shani -- Evaluating mechanisms of behavior change to inform and evaluate technology-based interventions / Amanda N. Baraldi, Ingrid C. Wurpts, David P. MacKinnon, Ginger Lockhart -- Economics analysis of technology-based behavioral health care systems / Daniel Polsky -- Models for effective dissemination and implementation of technology-based behavioral health care systems / Sarah Lord -- Privacy, security, and regulatory considerations as related to behavioral health information technology / Penelope P. Hughes, Melissa M. Goldstein --^ ; Harnessing mHealth in low-resource settings to overcome health system constraints and achieve universal access to health / Garrett Mehl, Lavanya Vasudevan, Lianne Gonsalves, Matt Berg, Tamsyn Seimon, Marleen Temmerman, Alain Labrique -- Open architecture and standards in mobile health / Julia E. Hoffman, Kelly M. Ramsey, Deborah Estrin -- Using technology to integrate behavioral health into primary care / Lola Awoyinka, David H. Gustafson, Roberta Johnson -- The potential of technology solutions for behavioral healthcare disparities / Michael Christopher Gibbons -- Behavioral health information technology adoption in the context of a changing healthcare landscape / Wendy Nilsen, Misha Pavel -- Envisioning the future : transformation of health care systems via technology / Lisa A. Marsch
    HBZ-ID HT018526848
    ISBN 978-0-19-931402-7 ; 0-19-931402-0
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Signal-difference-to-noise comparison of temporal subtraction, kV-switching dual-energy and photon-counting dual-energy x-ray angiography.

    Aubert, Sarah / Tanguay, Jesse

    Medical physics

    2023  Volume 50, Issue 12, Page(s) 7400–7414

    Abstract: Background: Dual-energy (DE) x-ray angiography with photon-counting detectors (PCDs) may enable single-exposure DE imaging of coronary vasculature.: Purpose: To compare the iodine signal-difference-to-noise ratio (SDNR) of single-exposure DE ... ...

    Abstract Background: Dual-energy (DE) x-ray angiography with photon-counting detectors (PCDs) may enable single-exposure DE imaging of coronary vasculature.
    Purpose: To compare the iodine signal-difference-to-noise ratio (SDNR) of single-exposure DE angiography with digital subtraction angiography (DSA) and kV-switching DE angiography for matched patient x-ray exposure.
    Methods: In a phantom study, we determined the technique parameters that maximized the iodine SDNR per root entrance air kerma for DSA, kV-switching DE angiography and single-exposure DE angiography. We measured SDNR from images of a phantom consisting of an iodine step-wedge immersed in a water tank of either 20  or 30 cm in thickness. We also imaged a phantom with simulated vessels embedded in background clutter and measured vessel SDNR. For this second phantom, we also applied anti-correlated noise reduction (ACNR) and calculated the resulting iodine SDNR. All images were acquired using a cadmium telluride PCD with two energy bins and analog charge summing for charge sharing suppression. The energy-discrimination capabilities were only used for the single-exposure DE approach. Optimized techniques were compared in terms of SDNR per root air kerma for two levels of x-ray scatter.
    Results: For the same patient x-ray exposure, the SDNR of single-exposure DE imaging without ACNR was 75% to 85% of that of kV-switching DE imaging (also without ACNR) and DSA, the latter two of which had nearly equal SDNR. The single-exposure DE approach required ∼50% of the tube load of the kV-switching approach to achieve the same SDNR. For matched patient air kermas, the single exposure approach required only ∼25% of the tube load of the kV-switching approach. ACNR increased SDNR by 2.4 and 3.0 for kV-switching and single-exposure DE imaging, respectively.
    Conclusions: Photon-counting, single-exposure DE angiography can suppress soft tissues and provide iodine SDNR levels comparable to DSA and kV-switching DE angiography for matched patient radiation exposures. When ACNR is used to reduce DE image noise, the SDNR of single-exposure DE imaging and kV-switching DE imaging exceed that of DSA by more than a factor of two. Compared to kV-switching DE imaging, single-exposure DE imaging requires substantially lower tube loading to achieve the same SDNR.
    MeSH term(s) Humans ; X-Rays ; Radiography ; Signal-To-Noise Ratio ; Phantoms, Imaging ; Angiography ; Iodine
    Chemical Substances Iodine (9679TC07X4)
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 188780-4
    ISSN 2473-4209 ; 0094-2405
    ISSN (online) 2473-4209
    ISSN 0094-2405
    DOI 10.1002/mp.16800
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lumbalpunktion – Schritt für Schritt

    Tumani, Hayrettin / Lewerenz, Jan / Jesse, Sarah

    Intensivmedizin up2date

    2023  Volume 19, Issue 01, Page(s) 10–16

    Language German
    Publishing date 2023-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2180698-6
    ISSN 1614-6697 ; 1614-4856
    ISSN (online) 1614-6697
    ISSN 1614-4856
    DOI 10.1055/a-1984-4050
    Database Thieme publisher's database

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  5. Article ; Online: Intravitreal injections with a low consumption technique have a low infection rate.

    Gale, Jesse / Welch, Sarah H / Niederer, Rachael

    Eye (London, England)

    2023  Volume 38, Issue 4, Page(s) 811–812

    MeSH term(s) Humans ; Intravitreal Injections ; Angiogenesis Inhibitors/therapeutic use ; Ranibizumab ; Retrospective Studies
    Chemical Substances Angiogenesis Inhibitors ; Ranibizumab (ZL1R02VT79)
    Language English
    Publishing date 2023-09-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02753-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exploring Different Contexts of Statin Deprescribing: A Vignette-Based Experiment with Older Adults Across Four Countries.

    Weir, Kristie Rebecca / Vordenberg, Sarah E / Scherer, Aaron M / Jansen, Jesse / Schoenborn, Nancy / Todd, Adam

    Journal of general internal medicine

    2024  

    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-024-08698-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Consensus recommendations on altered sensory functioning in Phelan-McDermid syndrome.

    Walinga, Margreet / Jesse, Sarah / Alhambra, Norma / Van Buggenhout, Griet

    European journal of medical genetics

    2023  Volume 66, Issue 5, Page(s) 104726

    Abstract: Altered sensory functioning is often observed in individuals with SHANK3 related Phelan-McDermid syndrome (PMS). Compared to typically developing individuals and individuals with an autism spectrum disorder, it has been suggested that there are ... ...

    Abstract Altered sensory functioning is often observed in individuals with SHANK3 related Phelan-McDermid syndrome (PMS). Compared to typically developing individuals and individuals with an autism spectrum disorder, it has been suggested that there are distinctive features of sensory functioning in PMS. More hyporeactivity symptoms and less hyperreactivity and sensory seeking behaviour are seen, particularly in the auditory domain. Hypersensitivity to touch, possible overheating or turning red easily and reduced pain response are often seen. In this paper the current literature on sensory functioning in PMS is reviewed and recommendations for caregivers, based on consensus within the European PMS consortium, are given.
    MeSH term(s) Humans ; Autism Spectrum Disorder/genetics ; Consensus ; Chromosome Disorders/genetics ; Chromosome Disorders/diagnosis ; Chromosome Deletion ; Chromosomes, Human, Pair 22/genetics
    Language English
    Publishing date 2023-02-14
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2184135-4
    ISSN 1878-0849 ; 1769-7212
    ISSN (online) 1878-0849
    ISSN 1769-7212
    DOI 10.1016/j.ejmg.2023.104726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Experimental optimization of single-exposure dual-energy angiography with photon-counting x-ray detectors.

    Aubert, Sarah / Tanguay, Jesse

    Medical physics

    2022  Volume 50, Issue 2, Page(s) 763–777

    Abstract: Background: Photon-counting x-ray detectors may enable single-exposure dual-energy (DE) x-ray angiography.: Purpose: The purpose of this paper is to experimentally optimize the energy thresholds and tube voltage for single-exposure DE x-ray ... ...

    Abstract Background: Photon-counting x-ray detectors may enable single-exposure dual-energy (DE) x-ray angiography.
    Purpose: The purpose of this paper is to experimentally optimize the energy thresholds and tube voltage for single-exposure DE x-ray angiography.
    Methods: We optimized single-exposure DE x-ray angiography using the iodine signal-difference-to-noise ratio (SDNR) per root patient air kerma (κ) as a figure of merit. We measured the iodine SDNR by imaging an iodine stepwedge immersed in a water tank with a depth of 30 cm in the direction of x-ray propagation. The stepwedge was imaged using tube voltages ranging from 90 to 150 kV and a cadmium telluride (CdTe) x-ray detector with two energy bins and analog charge summing for charge sharing suppression. The energy threshold that separates the two energy bins was varied from approximately 35 keV to approximately 75% of the maximum energy of the x-ray beam. Curve fitting was used to determine the threshold that maximized
    Results: The optimal energy thresholds increased monotonically from ∼50 to ∼85 keV over the range of tube voltages considered. For tube voltages greater than 90 kV, the optimal energy thresholds consistently allocated approximately two thirds of all detected primary photons to the low energy bin; this ratio was preserved without scatter. Consistent with prior modeling studies,
    Conclusions: Achieving optimal image quality in single-exposure DE angiography with photon-counting x-ray detectors will require high tube voltages (i.e., >130 kV) and, for thick patients, energy thresholds that allocate approximately two thirds of all primary photons to the low-energy image. Future work will compare the image quality of singe-exposure photon-counting and kV-switching approaches to DE x-ray angiography.
    MeSH term(s) Humans ; X-Rays ; Cadmium Compounds ; Photons ; Tellurium ; Quantum Dots ; Angiography ; Iodine ; Phantoms, Imaging
    Chemical Substances cadmium telluride (STG188WO13) ; Cadmium Compounds ; Tellurium (NQA0O090ZJ) ; Iodine (9679TC07X4)
    Language English
    Publishing date 2022-11-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 188780-4
    ISSN 2473-4209 ; 0094-2405
    ISSN (online) 2473-4209
    ISSN 0094-2405
    DOI 10.1002/mp.16079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Exosome complex components 1 and 2 are vital for early mammalian development.

    Srinivasan, Sanjana / He, Xinjian / Mirza, Sarah / Mager, Jesse

    Gene expression patterns : GEP

    2023  Volume 51, Page(s) 119346

    Abstract: Exosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/ ... ...

    Abstract Exosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant) embryos to determine developmental and molecular phenotypes of embryos lacking their functions. Our studies reveal that Exosc1 null embryos implant and form an egg cylinder but are developmentally delayed and fail to initiate gastrulation by embryonic day 7.5. In contrast, Exosc2 null embryos are lethal during peri-implantation stages, and while they do form a morphologically normal blastocyst at E3.5, they cannot be recovered at post-implantation stages. We show the absence of stage-specific developmental and altered lineage-specification in both Exosc1 and Exosc2 mutant embryos and conclude that these genes are essential for the successful progression through early mammalian development.
    MeSH term(s) Mice ; Animals ; Mice, Knockout ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Exosomes/genetics ; Blastocyst/metabolism ; Embryo Implantation/genetics ; Embryo, Mammalian/metabolism ; Mammals
    Chemical Substances Exosome Multienzyme Ribonuclease Complex (EC 3.1.-)
    Language English
    Publishing date 2023-11-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2058346-1
    ISSN 1872-7298 ; 1567-133X
    ISSN (online) 1872-7298
    ISSN 1567-133X
    DOI 10.1016/j.gep.2023.119346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Editorial: Towards a European consensus guideline for Phelan-McDermid syndrome.

    van Ravenswaaij-Arts, Conny M A / van Balkom, Ingrid D C / Jesse, Sarah / Bonaglia, Maria C

    European journal of medical genetics

    2023  Volume 66, Issue 5, Page(s) 104736

    MeSH term(s) Humans ; Chromosome Disorders/diagnosis ; Chromosome Disorders/genetics ; Chromosome Deletion ; Chromosomes, Human, Pair 22/genetics
    Language English
    Publishing date 2023-03-11
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2184135-4
    ISSN 1878-0849 ; 1769-7212
    ISSN (online) 1878-0849
    ISSN 1769-7212
    DOI 10.1016/j.ejmg.2023.104736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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