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  1. Article ; Online: Unknown: Papules on the nose. Diagnosis: Trichoblastomas.

    Gámez, Lucía / Reig, Irela / González, Antonio / Canosa, Adriana / Jordá, Esperanza

    Dermatology online journal

    2011  Volume 17, Issue 3, Page(s) 10

    MeSH term(s) Diagnosis, Differential ; Female ; Hair Diseases/pathology ; Humans ; Middle Aged ; Nose ; Nose Neoplasms/pathology ; Rare Diseases/pathology
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 1087-2108
    ISSN (online) 1087-2108
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  2. Article ; Online: Acral localized acquired cutis laxa.

    Martí, Nuria / Monteagudo, Carlos / Revert, Angeles / Reig, Irela / Gámez, Lucía / Jordá, Esperanza

    International journal of dermatology

    2013  Volume 52, Issue 8, Page(s) 983–986

    MeSH term(s) Biopsy ; Cutis Laxa/pathology ; Female ; Foot Dermatoses/pathology ; Hand Dermatoses/pathology ; Humans ; Middle Aged ; Skin/pathology ; Subcutaneous Tissue/pathology
    Language English
    Publishing date 2013-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/j.1365-4632.2011.04955.x
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  3. Article ; Online: Follicular mucinosis with loss of ephelides.

    Reig, Irela / Monteagudo, Carlos / Gámez, Lucía / Martí, Nuria / Martín, Jose M / Jorda, Esperanza

    International journal of dermatology

    2012  Volume 51, Issue 3, Page(s) 332–334

    MeSH term(s) Child ; Eyebrows ; Facial Dermatoses/pathology ; Hair Follicle/pathology ; Humans ; Male ; Melanosis/complications ; Melanosis/pathology ; Mucinosis, Follicular/complications ; Mucinosis, Follicular/pathology
    Language English
    Publishing date 2012-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/j.1365-4632.2011.04975.x
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  4. Article ; Online: Complete regression of a melanocytic nevus under intense pulsed light therapy for axillary hair removal in a cosmetic center.

    Martín, José M / Monteagudo, Carlos / Bella, Rebeca / Reig, Irela / Jordá, Esperanza

    Dermatology (Basel, Switzerland)

    2012  Volume 224, Issue 3, Page(s) 193–197

    Abstract: Intense pulsed light (IPL) therapy using noncoherent broad-spectrum light has been reported to be effective for hair removal, and also for treating superficial pigmented lesions like ephelides and solar lentigines. We report complete regression of a ... ...

    Abstract Intense pulsed light (IPL) therapy using noncoherent broad-spectrum light has been reported to be effective for hair removal, and also for treating superficial pigmented lesions like ephelides and solar lentigines. We report complete regression of a pigmented melanocytic nevus, histologically confirmed, after hair removal treatment with IPL. The use of lasers and IPL is a common procedure used by dermatologists and even other professions for the treatment of cosmetically troubling skin conditions. The main advantage of such treatment is a reduction of surgical scars, thus producing a favorable cosmetic outcome, but a major limitation is that histopathologic diagnosis is not usually obtained prior to treatment. Such devices should be carefully used in patients with potentially dangerous melanocytic lesions. We also review the recent literature regarding inadequate treatment of melanocytic lesions with lasers.
    MeSH term(s) Adult ; Female ; Hair Removal/methods ; Humans ; Nevus, Pigmented/diagnosis ; Nevus, Pigmented/pathology ; Nevus, Pigmented/therapy ; Phototherapy/methods ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology ; Skin Neoplasms/therapy ; Treatment Outcome
    Language English
    Publishing date 2012
    Publishing country Switzerland
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000338573
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  5. Article ; Online: Multiple cutaneous angiomyxomas in a child.

    Martí, Nuria / Jordá, Esperanza / Monteagudo, Carlos / Gámez, Lucía / Reig, Irela / Calduch, Luís

    Pediatric dermatology

    2011  Volume 28, Issue 4, Page(s) 462–464

    Abstract: Cutaneous myxomas are rare, benign, connective tissue tumors composed of stellate cells set in a loose mucoid stroma containing delicate reticulin fibers running in various directions. They are also called angiomyxomas to reinforce their vascular ... ...

    Abstract Cutaneous myxomas are rare, benign, connective tissue tumors composed of stellate cells set in a loose mucoid stroma containing delicate reticulin fibers running in various directions. They are also called angiomyxomas to reinforce their vascular component. These lesions have been recognized as part of Carney complex. We report an 11-year-old boy affected by disseminated cutaneous angiomyxomas since the age of 2, without any other component of Carney complex.
    MeSH term(s) Carney Complex/diagnosis ; Carney Complex/pathology ; Child ; Humans ; Male ; Myxoma/diagnosis ; Myxoma/pathology ; Neoplasms, Multiple Primary/diagnosis ; Neoplasms, Multiple Primary/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology ; Treatment Outcome
    Language English
    Publishing date 2011-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/j.1525-1470.2010.01291.x
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  6. Article ; Online: Neurofibromatosis-Noonan syndrome: case report and clinicopathogenic review of the Neurofibromatosis-Noonan syndrome and RAS-MAPK pathway.

    Reig, Irela / Boixeda, Pablo / Fleta, Beatriz / Morenoc, Carmen / Gámez, Lucía / Truchuelo, Mayte

    Dermatology online journal

    2011  Volume 17, Issue 4, Page(s) 4

    Abstract: Neurofibromatosis-Noonan syndrome is an entity that combines both features of Noonan syndrome and Neurofibromatosis type 1. This phenotypic overlap can be explained by the involvement of the RAS-MAPK pathway (mitogen-activated protein kinase) in both ... ...

    Abstract Neurofibromatosis-Noonan syndrome is an entity that combines both features of Noonan syndrome and Neurofibromatosis type 1. This phenotypic overlap can be explained by the involvement of the RAS-MAPK pathway (mitogen-activated protein kinase) in both disorders. We report the case of a 17-year-old boy with Neurofibromatosis 1 with Noonan-like features, who complained of the progressive appearance of blue-gray lesions on his back.
    MeSH term(s) Adolescent ; Back ; Humans ; Male ; Mitogen-Activated Protein Kinases/genetics ; Mitogen-Activated Protein Kinases/metabolism ; Mutation ; Neurofibromatoses/genetics ; Neurofibromatoses/metabolism ; Neurofibromatoses/pathology ; Noonan Syndrome/genetics ; Noonan Syndrome/metabolism ; Noonan Syndrome/pathology ; ras Proteins/genetics ; ras Proteins/metabolism
    Chemical Substances Mitogen-Activated Protein Kinases (EC 2.7.11.24) ; ras Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 1087-2108
    ISSN (online) 1087-2108
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  7. Article ; Online: Cicatricial pemphigoid of the Brunsting-Perry type.

    Martín, José M / Pinazo, Isabel / Molina, Inmaculada / Monteagudo, Carlos / Villalón, Guillermo / Reig, Irela / Jordá, Esperanza

    International journal of dermatology

    2009  Volume 48, Issue 3, Page(s) 293–294

    MeSH term(s) Alopecia/etiology ; Female ; Humans ; Middle Aged ; Pemphigoid, Benign Mucous Membrane/complications ; Pemphigoid, Benign Mucous Membrane/pathology ; Scalp Dermatoses/complications ; Scalp Dermatoses/pathology
    Language English
    Publishing date 2009-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/j.1365-4632.2009.03975.x
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  8. Article: Complete Regression of a Melanocytic Nevus under Intense Pulsed Light Therapy for Axillary Hair Removal in a Cosmetic Center

    Martín, José M. / Monteagudo, Carlos / Bella, Rebeca / Reig, Irela / Jordá, Esperanza

    Dermatology

    2012  Volume 224, Issue 3, Page(s) 193–197

    Abstract: Intense pulsed light (IPL) therapy using noncoherent broad-spectrum light has been reported to be effective for hair removal, and also for treating superficial pigmented lesions like ephelides and solar lentigines. We report complete regression of a ... ...

    Institution Departments of Dermatology and Pathology, Hospital Clínico Universitario de Valencia, Valencia, Spain
    Abstract Intense pulsed light (IPL) therapy using noncoherent broad-spectrum light has been reported to be effective for hair removal, and also for treating superficial pigmented lesions like ephelides and solar lentigines. We report complete regression of a pigmented melanocytic nevus, histologically confirmed, after hair removal treatment with IPL. The use of lasers and IPL is a common procedure used by dermatologists and even other professions for the treatment of cosmetically troubling skin conditions. The main advantage of such treatment is a reduction of surgical scars, thus producing a favorable cosmetic outcome, but a major limitation is that histopathologic diagnosis is not usually obtained prior to treatment. Such devices should be carefully used in patients with potentially dangerous melanocytic lesions. We also review the recent literature regarding inadequate treatment of melanocytic lesions with lasers.
    Keywords Regression ; Melanocytic lesions ; Intense pulsed light ; Laser ; Pseudomelanoma
    Language English
    Publishing date 2012-05-07
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Case and Review
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000338573
    Database Karger publisher's database

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  9. Article ; Online: Structural and mechanical analysis on mannuronate-rich alginate gels and xerogels beads based on Calcium, Copper and Zinc as crosslinkers

    Reig-Vano, Belen / Huck-Iriart, Cristian / de la Flor, Silvia / Trojanowska, Anna / Tylkowski, Bartosz / Giamberini, Marta

    International Journal of Biological Macromolecules. 2023 Aug., v. 246 p.125659-

    2023  

    Abstract: ... Fourier-Transform Infra-Red spectroscopy (FT-IR), Thermogravimetric Analysis (TGA), Small-Angle X-ray ... Calculations on Cu²⁺– and Zn²⁺–MM complexes. The results from FT-IR, compositional analysis and EXAFS ...

    Abstract Beads based on a mannuronate(M)-rich alginate (86 % M units) were prepared by adding the polysaccharide solution to a crosslinking bath containing different concentrations (0.5, 2 and 10 wt%) of XCl₂ where X = Ca, Cu or Zn. Primarily focus was on Zn, due to its antioxidant, anti-inflammatory and anti-microbial capabilities. The beads were characterized by Field-Emission Scanning Electron Microscopy (FESEM), Fourier-Transform Infra-Red spectroscopy (FT-IR), Thermogravimetric Analysis (TGA), Small-Angle X-ray Scattering (SAXS) and compression tests. The crosslinking agent significantly influenced the properties of the resulting beads. Specifically, Ca-based beads exhibited a smoother surface, while Cu- and Zn-based beads appeared rougher. Interestingly, Zn-based beads displayed a core-shell structure. Young moduli ranged from 3500 and 7000 MPa, with the highest values observed for Zn-beads. SAXS investigation at 0.5 wt% XCl₂ suggested increase in the densely packed domains amount in the order: Ca < Cu < Zn. Extended X-ray Absorption Fine Structure (EXAFS) showed that the coordination number was 4.3 ± 0.4 for Cu, and 4.0 ± 0.2 and 1.1 ± 0.1 for Zn in 0.5 wt% XCl₂ alginate xerogels, in agreement with reported Density Functional Calculations on Cu²⁺– and Zn²⁺–MM complexes. The results from FT-IR, compositional analysis and EXAFS collectively suggested a bridging coordination for these systems.
    Keywords X-ray absorption spectroscopy ; alginates ; antioxidants ; calcium ; cross-linking reagents ; crosslinking ; electron microscopy ; small-angle X-ray scattering ; thermogravimetry ; xerogels ; zinc ; Alginate gel ; Encapsulation ; Cation-crosslinking
    Language English
    Dates of publication 2023-08
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.125659
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers.

    Reig, Andres / Franasiak, Jason / Scott, Richard T / Seli, Emre

    Journal of assisted reproduction and genetics

    2020  Volume 37, Issue 3, Page(s) 595–602

    Abstract: ... 41-42 (n = 319), and > 42 (n = 243). Implantation rate (IR), clinical pregnancy rate (CPR), and LBR ... adjusting for confounders, women 38 years or older had a significantly lower IR than those under 35 (OR 0.85 ... did not differ significantly by age group. Other factors observed to affect IR independently were anti ...

    Abstract Purpose: The rate of embryonic aneuploidy increases with increasing female age and is the primary cause of lower pregnancy and live birth rates (LBR) in older reproductive age women. This retrospective cohort study evaluates single euploid embryo transfers to determine whether an age-related decline in reproductive efficiency persists.
    Methods: A total of 8175 non-donor single embryo transfers (SET) after pre-implantation testing for aneuploidy (PGT-A) and cryopreservation were included. These were divided into five groups by patient age: < 35 years old (n = 3789 embryos transferred), 35-37 (n = 2200), 38-40 (n = 1624), 41-42 (n = 319), and > 42 (n = 243). Implantation rate (IR), clinical pregnancy rate (CPR), and LBR were calculated for each group as a percentage of embryos transferred and compared. CPR was also analyzed as a percentage of implanted pregnancies, and LBR as a percentage of clinical pregnancies, to determine when age has the greatest impact. These results were then adjusted for confounding variables via a multivariate logistic regression model.
    Results: Implantation rates negatively correlated with age. After adjusting for confounders, women 38 years or older had a significantly lower IR than those under 35 (OR 0.85, 95%CI 0.73-0.99 for 38-40 years old; 0.69, 0.53-0.91 for 41-42, and 0.69, 0.51-0.94 for > 42). These differences are also apparent in CPR and LBR. The rates of progression to clinical pregnancy and live birth did not differ significantly by age group. Other factors observed to affect IR independently were anti-Müllerian hormone (AMH), day of embryo transfer, and embryo morphology.
    Conclusion: While selection of euploid embryos may be effective in overcoming a significant proportion of the age-related decline in reproductive efficiency, a decrease in IR, CPR, and LBR persists even when analyzing only euploid embryo transfers. The observed impact of aging is, therefore, independent of ploidy, as well as of other variables that affect reproductive efficiency. These results indicate that factors other than aneuploidy contribute to reproductive senescence.
    MeSH term(s) Adult ; Aneuploidy ; Blastocyst/metabolism ; Blastocyst/pathology ; Embryo Implantation/genetics ; Embryonic Development/genetics ; Female ; Fertilization in Vitro/methods ; Humans ; Live Birth/genetics ; Maternal Age ; Middle Aged ; Ovulation Induction/methods ; Ploidies ; Pregnancy ; Pregnancy Rate ; Preimplantation Diagnosis ; Single Embryo Transfer/methods
    Language English
    Publishing date 2020-03-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1112577-9
    ISSN 1573-7330 ; 1058-0468
    ISSN (online) 1573-7330
    ISSN 1058-0468
    DOI 10.1007/s10815-020-01739-0
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