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Article ; Online: His majesty's psychosis: the case of emperor Joshua Norton.

Lis, Eric

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

2015 Volume 39, Issue 2, Page(s) 181–185

Abstract: Case studies are a cornerstone of medical education and have been shown to be effective teaching tools. When teaching is entertaining, learning is enhanced and, therefore, strange and unusual cases present the opportunity to illustrate issues of disorder ...

Abstract	Case studies are a cornerstone of medical education and have been shown to be effective teaching tools. When teaching is entertaining, learning is enhanced and, therefore, strange and unusual cases present the opportunity to illustrate issues of disorder and illness in an engaging manner. The author illustrates this concept by presenting the life and character of Joshua Norton, who declared himself Emperor of the USA in 1859 and "reigned" until his death in 1880. Although grandiose claims are not rare among patients, Norton is unlike most self-proclaimed royalty in that his community embraced him and joined in with his fantasy. No psychiatrist or psychologist has ever opined on the matter of whether or not Norton's claims stemmed from mental disorder, and the author therefore presents Emperor Norton as a unique case in psychiatric history to explore first what diagnosis best explains his story and, second, whether he merits a diagnosis at all.
MeSH term(s)	Delusions/diagnosis ; Delusions/history ; History, 19th Century ; Humans ; Psychotic Disorders/diagnosis ; Psychotic Disorders/history ; Psychotic Disorders/psychology ; Social Perception ; Teaching ; Teaching Materials
Language	English
Publishing date	2015-04
Publishing country	United States
Document type	Historical Article ; Journal Article
ZDB-ID	1045331-3
ISSN	1545-7230 ; 1042-9670
ISSN (online)	1545-7230
ISSN	1042-9670
DOI	10.1007/s40596-014-0210-z
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Article: Feasibility and Safety of Cone-Beam Computed Tomography Advanced Navigation to Optimize Intra-arterial Chemotherapy Infusion of Skull Base Tumors

Cornelis, Francois H. / Lis, Eric / Tabar, Viviane / Lin, Andrew

Journal of Neurological Surgery Part B: Skull Base

2024

Abstract: Purpose: To assess the feasibility and safety of cone-beam computed tomography (CBCT) advanced navigation for optimizing intra-arterial chemotherapy infusion (IACI) in patients with skull base tumors.: Materials and Methods: Retrospective review on ... ...

Abstract	Purpose: To assess the feasibility and safety of cone-beam computed tomography (CBCT) advanced navigation for optimizing intra-arterial chemotherapy infusion (IACI) in patients with skull base tumors. Materials and Methods: Retrospective review on 10 consecutive IACI procedures performed in five patients (four women, 1 man) over a 1-year period. The median age of the patients was 71 years (interquartile range: 34–74). During the procedures, a CBCT-based navigation software was employed to evaluate tumor perfusion and guide the infusion methods. Catheterization of the primary tumor feeding vessel was performed in seven cases when it originated from the external carotid artery, whereas a temporary balloon-assisted occlusion technique was utilized in the remaining three cases where the tumor was primarily fed by the internal carotid artery. Carboplatin, topotecan, and melphalan were injected over a 10-minute period. Fluoroscopy time, reference dose, and Kerma area product, which estimates effective dose, were analyzed. Results: The technical success rate was 100%, with a median procedure length of 82 minutes (79–90). The median fluoroscopy time was 11.3 minutes (9.4–16.9), reference dose was 93.5 mGy (62–256.5), and Kerma area product was 11.6 Gy.cm 2 (9.5–25.4). The median effective dose was 3.8 mSv (1.5–5.1). The median follow-up duration was 233.5 days (186.3–432). One severe adverse event was reported, involving a right brachial hematoma and brachiocephalic artery dissection related to catheterization through a type III aortic arch. Three patients exhibited disease progression, but two patients showed stable disease. Conclusion: IACI for skull base tumors guided by CBCT navigation is both feasible and safe.
Keywords	cancer ; IACI ; CBCT ; skull base tumors ; interventional radiology
Language	English
Publishing date	2024-01-30
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/a-2257-5590
Database	Thieme publisher's database

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Article ; Online: Dynamic Contrast Enhanced MR Perfusion and Diffusion-Weighted Imaging of Marrow-Replacing Disorders of the Spine: A Comprehensive Review.

Yildirim, Onur / Peck, Kyung K / Saha, Atin / Karimi, Sasan / Lis, Eric

Radiologic clinics of North America

2023 Volume 62, Issue 2, Page(s) 287–302

Abstract: Significant advancements in cancer treatment have led to improved survival rates for patients, particularly in the context of spinal metastases. However, early detection and monitoring of treatment response remain crucial for optimizing patient outcomes. ...

Abstract	Significant advancements in cancer treatment have led to improved survival rates for patients, particularly in the context of spinal metastases. However, early detection and monitoring of treatment response remain crucial for optimizing patient outcomes. Although conventional imaging methods such as bone scan, PET, MR imaging, and computed tomography are commonly used for diagnosing and monitoring treatment, they present challenges in differential diagnoses and treatment response monitoring. This review article provides a comprehensive overview of the principles, applications, and practical uses of dynamic contrast-enhanced MR imaging and diffusion-weighted imaging in the assessment and monitoring of marrow-replacing disorders of the spine.
MeSH term(s)	Humans ; Bone Marrow ; Spinal Neoplasms ; Spine/pathology ; Diffusion Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/methods ; Diagnosis, Differential ; Perfusion
Language	English
Publishing date	2023-11-02
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	215712-3
ISSN	1557-8275 ; 0033-8389
ISSN (online)	1557-8275
ISSN	0033-8389
DOI	10.1016/j.rcl.2023.09.004
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Article ; Online: Dynamic Contrast-Enhanced MR Perfusion: Role in Diagnosis and Treatment Follow-Up in Patients with Vertebral Body Tumors.

Saha, Atin / Peck, Kyung K / Karimi, Sasan / Lis, Eric / Holodny, Andrei I

Neuroimaging clinics of North America

2023 Volume 33, Issue 3, Page(s) 477–486

Abstract: Recent therapeutic advances have led to increased survival times for patients with metastatic disease. Key to survival is early diagnosis and subsequent treatment as well as early detection of treatment failure allowing for therapy modifications. ... ...

Abstract	Recent therapeutic advances have led to increased survival times for patients with metastatic disease. Key to survival is early diagnosis and subsequent treatment as well as early detection of treatment failure allowing for therapy modifications. Conventional MR imaging techniques of the spine can be at times suboptimal for identifying viable tumor, as structural changes and imaging characteristics may not differ pretreatment and posttreatment. Advanced imaging techniques such as DCE-MRI can allow earlier and more accurate noninvasive assessment of viable disease by characterizing physiologic changes and tumor microvasculature.
MeSH term(s)	Humans ; Vertebral Body/pathology ; Follow-Up Studies ; Contrast Media ; Spinal Neoplasms/diagnostic imaging ; Spinal Neoplasms/therapy ; Magnetic Resonance Imaging/methods ; Perfusion
Chemical Substances	Contrast Media
Language	English
Publishing date	2023-05-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1314594-0
ISSN	1557-9867 ; 1052-5149
ISSN (online)	1557-9867
ISSN	1052-5149
DOI	10.1016/j.nic.2023.03.006
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Article ; Online: Embolization of Middle Meningeal Arteries for Symptomatic Subacute Subdural Hematoma in Patients with Cancer.

O'Gorman, Julianne / Geevarghese, Ruben / Bodard, Sylvain / Petre, Elena N / Brallier, Jess / Brennan, Cameron / Lis, Eric / Cornelis, Francois H

Academic radiology

2024

Abstract: Purpose: The purpose of this study was to evaluate the technical and clinical success of middle meningeal artery (MMA) embolization performed for symptomatic subacute subdural hematoma (SDH) in patients with cancer.: Methods: This study ... ...

Abstract	Purpose: The purpose of this study was to evaluate the technical and clinical success of middle meningeal artery (MMA) embolization performed for symptomatic subacute subdural hematoma (SDH) in patients with cancer. Methods: This study retrospectively included 23 consecutive patients (12 men, 11 women; median age 61 years, interquartile range: 55.5-75.5) who underwent 34 MMA angiograms for symptomatic SDH in 2022 and 2023. Median SDH thickness was 10.5 mm (7-12). Median platelet count was 117 K/mcL (54.5-218). 10 patients (43.5%, 10/23) had hematologic malignancies, seven patients (30.4%, 7/23) had surgery. Fluoroscopy time (FT), reference dose (RD), and kerma area product (Kap) were analyzed. Adverse events and outcomes were recorded. Results: The median imaging and clinical follow-up were 65 days (36.5-190.5) and 163 days (86-274), respectively. The technical success rate was 91.2% (31/34) as three MMA were not identified in two patients. Median procedure duration was 61 min (55.5-75.5). Median FT was 21.6 min (15.5-31.8); median RD was 158 mGy (96-256); and median Kap was 32.9 Gy.cm Conclusion: MMA embolization of symptomatic SDH in patients with cancer appears safe and is associated with improvement in clinical symptoms.
Language	English
Publishing date	2024-05-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	1355509-1
ISSN	1878-4046 ; 1076-6332
ISSN (online)	1878-4046
ISSN	1076-6332
DOI	10.1016/j.acra.2024.04.019
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Article ; Online: Chemical roadblocking of DNA transcription for nascent RNA display.

Strobel, Eric J / Lis, John T / Lucks, Julius B

The Journal of biological chemistry

2020 Volume 295, Issue 19, Page(s) 6401–6412

Abstract: Site-specific arrest of RNA polymerases (RNAPs) is fundamental to several technologies that assess RNA structure and function. ... ...

Abstract	Site-specific arrest of RNA polymerases (RNAPs) is fundamental to several technologies that assess RNA structure and function. Current
MeSH term(s)	DNA/chemistry ; DNA-Directed RNA Polymerases/chemistry ; Escherichia coli/enzymology ; Escherichia coli Proteins/chemistry ; RNA/biosynthesis ; RNA/chemistry ; Templates, Genetic ; Transcription, Genetic
Chemical Substances	Escherichia coli Proteins ; RNA (63231-63-0) ; DNA (9007-49-2) ; DNA-Directed RNA Polymerases (EC 2.7.7.6)
Language	English
Publishing date	2020-03-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2997-x
ISSN	1083-351X ; 0021-9258
ISSN (online)	1083-351X
ISSN	0021-9258
DOI	10.1074/jbc.RA120.012641
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Article ; Online: Development and Dark Wizards: Teaching Psychopathology with Lord Voldemort.

Lis, Eric / Tuineag, Maria

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

2017 Volume 41, Issue 2, Page(s) 285–288

Language	English
Publishing date	2017
Publishing country	United States
Document type	Journal Article
ZDB-ID	1045331-3
ISSN	1545-7230 ; 1042-9670
ISSN (online)	1545-7230
ISSN	1042-9670
DOI	10.1007/s40596-017-0676-6
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Article ; Online: Feasibility and Safety of Percutaneous CT-Guided Bone Biopsies in Patients with Cancer Using a Patient-Mounted Robotic System: A Retrospective Analysis of 40 Consecutive Biopsies.

Witkowska, Agnieszka / Petre, Elena N / Moussa, Amgad M / Santos, Ernesto / Sarkar, Debkumar / Lis, Eric / Cornelis, Francois H

Journal of vascular and interventional radiology : JVIR

2023 Volume 34, Issue 12, Page(s) 2174–2179

Abstract: This retrospective study evaluated the feasibility and safety of percutaneous computed tomography (CT)-guided bone biopsies in patients with cancer using a patient-mounted robotic system with steering capabilities. The study included 39 patients (17 ... ...

Abstract	This retrospective study evaluated the feasibility and safety of percutaneous computed tomography (CT)-guided bone biopsies in patients with cancer using a patient-mounted robotic system with steering capabilities. The study included 39 patients (17 women, 22 men; median age, 65.5 years; interquartile range [IQR], 54.8-71.0 years). Forty biopsies were performed in the pelvis, spine, ribs, shoulder, femur, and sternum. The technical success rate was 100%, and the median trajectory length was 55.9 mm (IQR, 47.1-73.6 mm). Intermediate checkpoints were used in 8 biopsies. Median time from the first to final scan was 21 minutes (IQR, 17-37 minutes). The overall procedure time was 30 minutes (IQR, 24-36 minutes). The median dose length product and effective dose were 536.6 mGy⋅cm (IQR, 396.2-837.7 mGy∗cm) and 7.1 mSv (IQR, 4.7-10.8 mSv), respectively. No adverse events occurred. The diagnostic yield for cancer was 72.5%. Percutaneous robotic-assisted bone biopsies demonstrated high technical success, adequate diagnostic yield, and favorable safety profile.
MeSH term(s)	Male ; Humans ; Female ; Aged ; Retrospective Studies ; Feasibility Studies ; Robotic Surgical Procedures/adverse effects ; Image-Guided Biopsy/adverse effects ; Image-Guided Biopsy/methods ; Tomography, X-Ray Computed/methods ; Neoplasms/diagnostic imaging
Language	English
Publishing date	2023-09-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1137756-2
ISSN	1535-7732 ; 1051-0443
ISSN (online)	1535-7732
ISSN	1051-0443
DOI	10.1016/j.jvir.2023.08.040
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Article ; Online: Preoperative Embolization of Metastatic Spinal Cord Compression with n-Butyl Cyanoacrylate: Safety and Effectiveness in Limiting Blood Loss.

Youssef, Eslam / Santos, Ernesto / Moussa, Amgad M / Lis, Eric / Vaynrub, Maksim / Barzilai, Ori / Bilsky, Mark / Cornelis, Francois H

Journal of vascular and interventional radiology : JVIR

2023 Volume 34, Issue 4, Page(s) 613–618

Abstract: Purpose: To evaluate the safety and effectiveness of preoperative embolization with n-butyl cyanoacrylate (nBCA) performed for metastatic spinal cord compression (MSCC) in limiting blood loss (BL).: Materials and methods: In this institutional review ...

Abstract	Purpose: To evaluate the safety and effectiveness of preoperative embolization with n-butyl cyanoacrylate (nBCA) performed for metastatic spinal cord compression (MSCC) in limiting blood loss (BL). Materials and methods: In this institutional review board-approved retrospective study, clinical records from 2017 to 2022 were reviewed. Twenty consecutive patients (11 men and 9 women; mean age, 65.8 years ± 10.0; range, 45-82 years) underwent 21 preoperative spine tumor embolizations with nBCA. Angiograms were used to calculate the percentage reduction in tumor vascularity, and relevant clinical data (levels studied and embolized, fluoroscopy time [FT], reference dose [RD], and Kerma area product [KAP]) and operative data (BL and operative time [OT]) were analyzed. Adverse events and outcomes were recorded. Results: A median of 2 levels were embolized per procedure (range, 1-5) but 4.9 were studied (range, 1-10). After embolization, tumor blush was reduced by a median of 87.3% (range, 50%-90%). The mean FT was 41 minutes ± 15.4 (range, 16-67 minutes), the mean RD was 1,977.1 mGy ± 1,794.3 (range, 450.2-6,319 mGy), and the mean KAP was 180.5 Gy·cm Conclusions: Preoperative embolization of tumors resected for MSCC with nBCA is a safe procedure allowing for performance of surgery with acceptable BL.
MeSH term(s)	Male ; Humans ; Female ; Aged ; Enbucrilate/adverse effects ; Spinal Cord Compression/diagnostic imaging ; Spinal Cord Compression/etiology ; Spinal Cord Compression/therapy ; Retrospective Studies ; Treatment Outcome ; Blood Loss, Surgical ; Embolization, Therapeutic/adverse effects ; Embolization, Therapeutic/methods
Chemical Substances	Enbucrilate (F8CEP82QNP)
Language	English
Publishing date	2023-01-14
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1137756-2
ISSN	1535-7732 ; 1051-0443
ISSN (online)	1535-7732
ISSN	1051-0443
DOI	10.1016/j.jvir.2023.01.009
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Article: Mixotrophic Growth of

Lacroux, Julien / Seira, Jordan / Trably, Eric / Bernet, Nicolas / Steyer, Jean-Philippe / van Lis, Robert

Frontiers in microbiology

2021 Volume 12, Page(s) 703614

Abstract: Microalgae can be cultivated on waste dark fermentation effluents containing volatile fatty acids (VFA) such as acetate or butyrate. These VFA can however inhibit microalgae growth at concentrations above 0.5-1 ... ...

Abstract	Microalgae can be cultivated on waste dark fermentation effluents containing volatile fatty acids (VFA) such as acetate or butyrate. These VFA can however inhibit microalgae growth at concentrations above 0.5-1 g
Language	English
Publishing date	2021-07-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2021.703614
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