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  1. Article ; Online: PET/MRI: A New Frontier in Breast Cancer Imaging.

    Ho, Annette M / Kalantari, Babak N

    The breast journal

    2016  Volume 22, Issue 3, Page(s) 261–263

    MeSH term(s) Breast Neoplasms ; Fluorodeoxyglucose F18 ; Humans ; Magnetic Resonance Imaging ; Multimodal Imaging ; Positron-Emission Tomography ; Radiopharmaceuticals
    Chemical Substances Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/tbj.12570
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Determination of Factors Associated with Upstage in Atypical Ductal Hyperplasia to Identify Low-Risk Patients Where Active Surveillance May be an Alternative.

    Greene, Alexandra J E / Davis, Joshua / Moon, Jessica / Dubin, Iram / Cruz, Anastasia / Gupta, Megha / Moazzez, Ashkan / Ozao-Choy, Junko / Gupta, Esha / Manchandia, Tejas / Kalantari, Babak N / Rahbar, Guita / Dauphine, Christine

    Annals of surgical oncology

    2024  Volume 31, Issue 5, Page(s) 3177–3185

    Abstract: Background: Excision is routinely recommended for atypical ductal hyperplasia (ADH) found on core biopsy given cancer upstage rates of near 20%. Identifying a cohort at low-risk for upstage may avoid low-value surgery. Objectives were to elucidate ... ...

    Abstract Background: Excision is routinely recommended for atypical ductal hyperplasia (ADH) found on core biopsy given cancer upstage rates of near 20%. Identifying a cohort at low-risk for upstage may avoid low-value surgery. Objectives were to elucidate factors predictive of upstage in ADH, specifically near-complete core sampling, to potentially define a group at low upstage risk.
    Patients and methods: This retrospective, cross-sectional, multi-institutional study from 2015 to 2019 of 221 ADH lesions in 216 patients who underwent excision or active observation (≥ 12 months imaging surveillance, mean follow-up 32.6 months) evaluated clinical, radiologic, pathologic, and procedural factors for association with upstage. Radiologists prospectively examined imaging for lesional size and sampling proportion.
    Results: Upstage occurred in 37 (16.7%) lesions, 25 (67.6%) to ductal carcinoma in situ (DCIS) and 12 (32.4%) to invasive cancer. Factors independently predictive of upstage were lesion size ≥ 10 mm (OR 5.47, 95% CI 2.03-14.77, p < 0.001), pathologic suspicion for DCIS (OR 12.29, 95% CI 3.24-46.56, p < 0.001), and calcification distribution pattern (OR 8.08, 95% CI 2.04-32.00, p = 0.003, "regional"; OR 19.28, 95% CI 3.47-106.97, p < 0.001, "linear"). Near-complete sampling was not correlated with upstage (p = 0.64). All three significant predictors were absent in 65 (29.4%) cases, with a 1.5% upstage rate.
    Conclusions: The upstage rate among 221 ADH lesions was 16.7%, highest in lesions ≥ 10 mm, with pathologic suspicion of DCIS, and linear/regional calcifications on mammography. Conversely, 30% of the cohort exhibited all low-risk factors, with an upstage rate < 2%, suggesting that active surveillance may be permissible in lieu of surgery.
    MeSH term(s) Female ; Humans ; Biopsy, Large-Core Needle ; Breast/pathology ; Breast Neoplasms/diagnosis ; Breast Neoplasms/surgery ; Breast Neoplasms/pathology ; Calcinosis/pathology ; Carcinoma, Ductal, Breast/surgery ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Intraductal, Noninfiltrating/surgery ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Cross-Sectional Studies ; Hyperplasia/pathology ; Mammography ; Retrospective Studies ; Watchful Waiting
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-024-15041-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Does diagnostic mammography need to be a routine component of the initial evaluation of a breast symptom in women 30-39 years of age?

    Neal, Jasmin C / Saith, Sunita / Khong-McBride, Christine / Kalantari, Babak N / Ho, Annette / Ariazand, Vishtasb / Ozao-Choy, Junko / Dauphine, Christine

    The breast journal

    2021  Volume 27, Issue 4, Page(s) 330–334

    Abstract: Diagnostic mammography is routinely ordered, along with targeted breast ultrasound, to evaluate breast symptoms in women 30-39 years of age. However, in this age group, mammography is often limited by breast density and the probability of detecting an ... ...

    Abstract Diagnostic mammography is routinely ordered, along with targeted breast ultrasound, to evaluate breast symptoms in women 30-39 years of age. However, in this age group, mammography is often limited by breast density and the probability of detecting an occult malignancy is low. We sought to evaluate whether diagnostic mammography detected any new incidental malignancies in women aged 30-39 years presenting with focal breast symptoms. This retrospective study included women 30-39 years of age who had a diagnostic mammogram performed for focal breast symptoms at a single institution from 2002 to 2017. Descriptive analyses were performed to determine the rate of incidental mammographic findings outside of the region of the presenting symptom that 1) led to additional imaging and/or biopsies and 2) were found to be malignant. During the 16-year study period, 1770 evaluations were performed, of which 249 (14.1%) were found to have an additional incidental mammographic abnormality. Further diagnostic imaging was required in 211 (11.3%), core biopsy in 67 (3.8%), and excisional biopsy in 8 (0.5%). None of the mammographically detected incidental findings resulted in a new diagnosis of breast cancer. In the evaluation of focal benign breast symptoms in women 30-39 years of age, diagnostic mammography did not detect any new incidental malignancies outside of the area of interest, but instead led to additional unavailing imaging and biopsy procedures. The mammography component of the diagnostic evaluation of younger average-risk women may potentially be omitted if the presenting symptom is determined to be benign with ultrasound alone.
    MeSH term(s) Breast/diagnostic imaging ; Breast Neoplasms/diagnostic imaging ; Female ; Humans ; Mammography ; Retrospective Studies ; Ultrasonography, Mammary
    Language English
    Publishing date 2021-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/tbj.14199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The role of imaging in the evaluation of focal mastalgia.

    Kalantari, Babak N / Dauphine, Christine E / Khalkhali, Iraj

    The breast journal

    2013  Volume 19, Issue 6, Page(s) 569–570

    MeSH term(s) Breast Diseases/diagnosis ; Female ; Humans ; Mammography ; Ultrasonography, Mammary
    Language English
    Publishing date 2013-11
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/tbj.12179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Squamous Cell Carcinoma Arising in Breast Implant Capsules.

    Goldberg, Mytien Thi / Llaneras, Jason / Willson, Thomas D / Boyd, John Brain / Venegas, Rose J / Dauphine, Christine / Kalantari, Babak N

    Annals of plastic surgery

    2020  Volume 86, Issue 3, Page(s) 268–272

    Abstract: Abstract: Breast augmentation and reconstruction utilizing implants are among the most common plastic surgery procedures performed in the United States. A small proportion of these implants are removed each year. We report 2 cases where routine ... ...

    Abstract Abstract: Breast augmentation and reconstruction utilizing implants are among the most common plastic surgery procedures performed in the United States. A small proportion of these implants are removed each year. We report 2 cases where routine pathologic evaluation of capsulectomy specimens revealed squamous cell carcinoma associated with the breast implant capsule and discuss the possible pathogenesis of this unusual entity. Both patients had long-standing implants (>10 years) and presented with acute unilateral breast erythema and swelling. Intraoperatively, the capsules for both cases appeared thickened and calcified, containing extensive granulomatosis and keratinaceous debris invading into the chest wall. Extensive workup failed to find an occult primary. One patient died from a malignant pleural effusion secondary to tumor invasion during chemotherapy, and the second patient obtained stabilization of the mass after 5 weeks of chemotherapy but subsequently declined further surgical intervention. A thorough literature review was performed, and 5 similar reports were identified, involving 6 patients. All patients presented with similar clinical presentations as ours and had poor outcomes. The mean reporting age at diagnosis was 60 years, and the average time from initial implant to diagnosis was 25 years. Due to the small numbers of squamous cell carcinomas associated with breast implant capsules, the true association between the 2 is unknown. It is postulated that chronic inflammation/irritation from the breast implant and epithelialization of the capsule play a significant role in the disease process. This may represent a new entity of "chronic inflammatory capsular malignancies." Increased awareness of this entity may allow for earlier suspicion, diagnosis, and management.
    MeSH term(s) Breast Implantation ; Breast Implants/adverse effects ; Breast Neoplasms/surgery ; Capsules ; Carcinoma, Squamous Cell/etiology ; Carcinoma, Squamous Cell/surgery ; Humans ; Mammaplasty
    Chemical Substances Capsules
    Language English
    Publishing date 2020-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 423835-7
    ISSN 1536-3708 ; 0148-7043
    ISSN (online) 1536-3708
    ISSN 0148-7043
    DOI 10.1097/SAP.0000000000002524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lymphoepithelioma-like carcinoma of the breast.

    Nankin, Nils L / Gondusky, Christina J / Abasolo, Peter A / Kalantari, Babak N

    Radiology case reports

    2015  Volume 10, Issue 1, Page(s) 963

    Abstract: Lymphoepithelioma-like carcinoma of the breast is a rare malignancy, with fewer than 20 cases documented in the literature. Given the paucity of reported cases, there is limited information available to guide the diagnosis and management of patients with ...

    Abstract Lymphoepithelioma-like carcinoma of the breast is a rare malignancy, with fewer than 20 cases documented in the literature. Given the paucity of reported cases, there is limited information available to guide the diagnosis and management of patients with this tumor. We present a case of a 39-year-old woman with a palpable right breast mass that was initially diagnosed by core needle biopsy as infiltrating carcinoma with prominent lymphoplasmacytic stroma. Subsequent neoadjuvant chemotherapy with docetaxel, doxorubicin, and cyclophosphamide resulted in a marked decrease in the size of the mass. After wide local surgical excision, pathology revealed a lymphoepithelioma-like carcinoma of the breast. Given the excellent treatment response, our experience may help clinicians determine future therapeutic strategies for this rare breast tumor.
    Language English
    Publishing date 2015-12-03
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.2484/rcr.v10i1.963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Neuroimaging of tuberous sclerosis: spectrum of pathologic findings and frontiers in imaging.

    Kalantari, Babak N / Salamon, Noriko

    AJR. American journal of roentgenology

    2008  Volume 190, Issue 5, Page(s) W304–9

    Abstract: Objective: The purpose of this article is to present neuroimaging findings in tuberous sclerosis complex, including recently developed imaging techniques that have demonstrated clinical benefit to this patient population.: Conclusion: Neuroimaging ... ...

    Abstract Objective: The purpose of this article is to present neuroimaging findings in tuberous sclerosis complex, including recently developed imaging techniques that have demonstrated clinical benefit to this patient population.
    Conclusion: Neuroimaging advances have improved the diagnosis of tuberous sclerosis complex and the treatment of children with this condition. Superimposition of functional information from PET onto MRI allows accurate and noninvasive identification of epileptogenic tubers, improving surgical cure rates. Magnetic source imaging can also be used to localize epileptiform activity arising from tubers.
    MeSH term(s) Diffusion Magnetic Resonance Imaging ; Epilepsy/etiology ; Epilepsy/pathology ; Epilepsy/therapy ; Humans ; Magnetoencephalography ; Positron-Emission Tomography ; Tuberous Sclerosis/diagnosis ; Tuberous Sclerosis/pathology ; Tuberous Sclerosis/therapy
    Language English
    Publishing date 2008-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.07.2928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Examining the role of screening mammography in men at moderate risk for breast cancer: two illustrative cases.

    Gondusky, Christina J / Kim, Michelle J / Kalantari, Babak N / Khalkhali, Iraj / Dauphine, Christine E

    The breast journal

    2015  Volume 21, Issue 3, Page(s) 316–317

    MeSH term(s) Breast Neoplasms, Male/diagnostic imaging ; Breast Neoplasms, Male/pathology ; Breast Neoplasms, Male/prevention & control ; Humans ; Klinefelter Syndrome/complications ; Male ; Mass Screening/methods ; Middle Aged ; Radiography ; Risk Factors ; Transgender Persons
    Language English
    Publishing date 2015-05
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/tbj.12411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Utility of short-interval follow-up mammography after a benign-concordant stereotactic breast biopsy result.

    Maldonado, Sean / Gandhi, Nishant / Ha, Tony / Choi, Patrick / Khalkhali, Iraj / Kalantari, Babak N / Dauphine, Christine

    Breast (Edinburgh, Scotland)

    2018  Volume 42, Page(s) 50–53

    Abstract: ... pathology. The cost of short-interval mammographic follow-up (n = 207) was calculated at $28,541.16 ...

    Abstract Background: There is currently no clear consensus recommendation for the use of short-interval follow-up mammography after a benign-concordant breast biopsy (BCBB), and practice patterns vary widely. The objectives of this study were to evaluate whether a short-interval follow-up mammogram provided clinical utility after stereotactic BCBB and to examine the costs associated with this surveillance strategy.
    Methods: A retrospective review of women who underwent a stereotactic breast biopsy yielding benign-concordant results between January 2005 and October 2014 was performed to evaluate findings on subsequent imaging, to calculate compliance with recommended short-interval imaging, and to examine whether subsequent imaging revealed an abnormality at the site of the initial stereotactic BCBB. A cost analysis was performed utilizing Medicare reimbursement rates to calculate projected and actual costs of short-interval follow-up imaging after stereotactic BCBB.
    Results: Of the 470 stereotactic BCBB performed, a short-interval mammogram was completed in 207 (44.0%), 9 (4.3%) of which had suspicious mammographic findings at the initial biopsy site, and 6 subsequently underwent biopsy, with none resulting in malignant or high-risk pathology. The cost of short-interval mammographic follow-up (n = 207) was calculated at $28,541.16.
    Conclusions: This study provides evidence that 6-month follow-up mammography has low clinical utility and unnecessarily increases costs after stereotactic BCBB. A safe and more cost-effective strategy may be resumption of routine mammography at 12 months post-biopsy.
    MeSH term(s) Adult ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/economics ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Early Detection of Cancer/economics ; Early Detection of Cancer/statistics & numerical data ; Female ; Follow-Up Studies ; Humans ; Image-Guided Biopsy/economics ; Image-Guided Biopsy/statistics & numerical data ; Mammography/economics ; Mammography/statistics & numerical data ; Middle Aged ; Neoplasm Staging ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 2018-08-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1143210-x
    ISSN 1532-3080 ; 0960-9776
    ISSN (online) 1532-3080
    ISSN 0960-9776
    DOI 10.1016/j.breast.2018.08.101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Machine Learning versus Mathematical Model to Estimate the Transverse Shear Stress Distribution in a Rectangular Channel

    Lashkar-Ara, Babak / Kalantari, Niloofar / Khozani, Zohreh Sheikh / Mosavi, Amir

    2021  

    Abstract: One of the most important subjects of hydraulic engineering is the reliable estimation of the transverse distribution in the rectangular channel of bed and wall shear stresses. This study makes use of the Tsallis entropy, genetic programming (GP) and ... ...

    Abstract One of the most important subjects of hydraulic engineering is the reliable estimation of the transverse distribution in the rectangular channel of bed and wall shear stresses. This study makes use of the Tsallis entropy, genetic programming (GP) and adaptive neuro-fuzzy inference system (ANFIS) methods to assess the shear stress distribution (SSD) in the rectangular channel. To evaluate the results of the Tsallis entropy, GP and ANFIS models, laboratory observations were used in which shear stress was measured using an optimized Preston tube. This is then used to measure the SSD in various aspect ratios in the rectangular channel. To investigate the shear stress percentage, 10 data series with a total of 112 different data were used. The results of the sensitivity analysis show that the most influential parameter for the SSD in a smooth rectangular channel is the dimensionless parameter B/H, Where the transverse coordinate is B, and the flow depth is H. With the parameters (b/B), (B/H) for the bed and (z/H), (B/H) for the wall as inputs, the modeling of the GP was better than the other one. Based on the analysis, it can be concluded that the use of GP and ANFIS algorithms is more effective in estimating shear stress in smooth rectangular channels than the Tsallis entropy-based equations.

    Comment: 16 pages, 8 figures
    Keywords Physics - Fluid Dynamics ; Computer Science - Machine Learning ; Computer Science - Neural and Evolutionary Computing ; 68T07
    Publishing date 2021-03-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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